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Volumn 40, Issue 18, 2011, Pages 4855-4864
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Impact of metal binding on the antitumor activity and cellular imaging of a metal chelator cationic imidazopyridine derivative
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Author keywords
[No Author keywords available]
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Indexed keywords
ANTI-TUMOR ACTIVITIES;
ANTICANCER ACTIVITIES;
APOPTOSIS;
CASPASES;
CELL CYCLE;
CELL CYCLE ANALYSIS;
CELLULAR IMAGING;
DEAD CELLS;
DNA CLEAVAGE;
ENHANCED UPTAKE;
FLUORESCENCE IMAGING;
FLUORESCENCE QUANTUM YIELD;
HOECHST 33258;
IMIDAZOPYRIDINES;
IN-CELL;
JURKAT CELL;
LIFE-TIMES;
METAL BINDING;
METAL CHELATOR;
MINOR GROOVES;
NUCLEAR MORPHOLOGY;
PHOTODYNAMIC EFFECT;
SINGLET OXYGEN;
UV-A LIGHT;
WATERSOLUBLE;
BROMINE COMPOUNDS;
CELL CULTURE;
CELL DEATH;
CELL PROLIFERATION;
CHELATION;
DYES;
FLUORESCENCE;
METAL IONS;
NUCLEIC ACIDS;
OXYGEN;
QUANTUM YIELD;
ZINC;
METALS;
(1E) 1 ((PYRIDIN 2 YL)METHYLENEAMINO) 3 (3 (PYRIDIN 2 YL)IMIDAZO(1,5 A)PYRIDIN 2(3H) YL)PROPAN 2 OL;
(1E)-1-((PYRIDIN-2-YL)METHYLENEAMINO)-3-(3-(PYRIDIN-2-YL)IMIDAZO(1,5-A)PYRIDIN-2(3H)-YL)PROPAN-2-OL;
ANTINEOPLASTIC AGENT;
CATION;
CHELATING AGENT;
FLUORESCENT DYE;
IMIDAZOLE DERIVATIVE;
IRON;
PYRIDINE;
PYRIDINE DERIVATIVE;
REACTIVE OXYGEN METABOLITE;
ZINC;
APOPTOSIS;
ARTICLE;
CELL CYCLE G1 PHASE;
CHEMISTRY;
DNA CLEAVAGE;
FLUORESCENCE MICROSCOPY;
HUMAN;
METABOLISM;
NEOPLASM;
TUMOR CELL LINE;
ANTINEOPLASTIC AGENTS;
APOPTOSIS;
CATIONS;
CELL LINE, TUMOR;
CHELATING AGENTS;
DNA CLEAVAGE;
FLUORESCENT DYES;
G1 PHASE;
HUMANS;
IMIDAZOLES;
IRON;
MICROSCOPY, FLUORESCENCE;
NEOPLASMS;
PYRIDINES;
REACTIVE OXYGEN SPECIES;
ZINC;
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EID: 79954992380
PISSN: 14779226
EISSN: 14779234
Source Type: Journal
DOI: 10.1039/c0dt01717e Document Type: Article |
Times cited : (43)
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References (57)
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