Transmembrane helix 7 in the Na+/dicarboxylate cotransporter 1 is an outer helix that contains residues critical for function

Biochimica et Biophysica Acta - Biomembranes

Volumn 1808, Issue 6, 2011, Pages 1454-1461

  Pajor, Ana M ^a   Sun, Nina N ^a   Joshi, Aditya D ^b   Randolph, Kathleen M ^c  

^a UNIVERSITY OF CALIFORNIA SAN DIEGO   (United States)

^b BAYLOR COLLEGE OF MEDICINE   (United States)

^c UNIVERSITY OF TEXAS MEDICAL BRANCH   (United States)

Author keywords

Cysteine substitution; Methanethiosulfonate reagents; Site directed mutagenesis; SLC13 family; Sodium; Succinate

Indexed keywords

AMINO ACID; CITRIC ACID; CYSTEINE; MEMBRANE PROTEIN; SODIUM DICARBOXYLATE COTRANSPORTER 1; SUCCINIC ACID; UNCLASSIFIED DRUG;

ARTICLE; CELL MEMBRANE; CELL STRAIN COS7; CELL SURFACE; CONTROLLED STUDY; MUTANT; NUCLEOTIDE SEQUENCE; PRIORITY JOURNAL; PROTEIN EXPRESSION; PROTEIN FUNCTION; PROTEIN SECONDARY STRUCTURE; PROTEIN TRANSPORT; SITE DIRECTED MUTAGENESIS; TRANSMEMBRANE HELIX 7;

AMINO ACID SEQUENCE; AMINO ACID SUBSTITUTION; ANIMALS; BIOLOGICAL TRANSPORT; CELL MEMBRANE; CERCOPITHECUS AETHIOPS; COS CELLS; DICARBOXYLIC ACID TRANSPORTERS; HELA CELLS; HUMANS; IMMUNOBLOTTING; KINETICS; MESYLATES; MOLECULAR SEQUENCE DATA; MUTATION; ORGANIC ANION TRANSPORTERS, SODIUM-DEPENDENT; PROTEIN STRUCTURE, SECONDARY; RABBITS; SEQUENCE HOMOLOGY, AMINO ACID; SUCCINIC ACID; SULFHYDRYL REAGENTS; SYMPORTERS;

EID: 79954734126     PISSN: 00052736     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.bbamem.2010.11.007     Document Type: Article

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