-
1
-
-
0041821836
-
A perspective on enzyme catalysis
-
Benkovic SJ, Hammes-Schiffer S: A perspective on enzyme catalysis. Science 2003, 301:1196-1202.
-
(2003)
Science
, vol.301
, pp. 1196-1202
-
-
Benkovic, S.J.1
Hammes-Schiffer, S.2
-
2
-
-
0016624901
-
Binding energy, specificity, and enzymic catalysis: The Circe effect
-
Jencks WP: Binding energy, specificity, and enzymic catalysis: the Circe effect. Adv Enzymol 1975, 43:219-410.
-
(1975)
Adv Enzymol
, vol.43
, pp. 219-410
-
-
Jencks, W.P.1
-
3
-
-
0024381294
-
Role of substrate binding forces in exchange-only transport systems: I. Transition-state theory
-
Krupka RM: Role of substrate binding forces in exchange-only transport systems: I. Transition-state theory. J Membr Biol 1989, 109:151-158.
-
(1989)
J Membr Biol
, vol.109
, pp. 151-158
-
-
Krupka, R.M.1
-
4
-
-
0842271085
-
Stabilization of Transition States and Exclusion of Water
-
London, New Science Press
-
Petsko GA, Ringe D: Stabilization of Transition States and Exclusion of Water. In Protein Structure and Function London, New Science Press; 2004:68.
-
(2004)
Protein Structure and Function
, pp. 68
-
-
Petsko, G.A.1
Ringe, D.2
-
5
-
-
0346843109
-
Use of the "Transport Specificity Ratio" and Cysteine-Scanning Mutagenesis to Identify Multiple Substrate Specificity Determinants within the "Consensus Amphipathic Region" of the Escherichia coli GABA Transporter encoded by gabP
-
King SC, Brown-Istvan L: Use of the "Transport Specificity Ratio" and Cysteine-Scanning Mutagenesis to Identify Multiple Substrate Specificity Determinants within the "Consensus Amphipathic Region" of the Escherichia coli GABA Transporter encoded by gabP. Biochem J 2003, 376:633-644.
-
(2003)
Biochem J
, vol.376
, pp. 633-644
-
-
King, S.C.1
Brown-Istvan, L.2
-
6
-
-
0346843111
-
Induction of Substrate Specificity Shifts by Placement of Alanine Insertions within the Consensus Amphipathic Region of the Escherichia coli GABA Transporter encoded by gabP
-
King SC, Hu LA, Pugh A: Induction of Substrate Specificity Shifts by Placement of Alanine Insertions within the Consensus Amphipathic Region of the Escherichia coli GABA Transporter encoded by gabP. Biochem J 2003, 376:645-653.
-
(2003)
Biochem J
, vol.376
, pp. 645-653
-
-
King, S.C.1
Hu, L.A.2
Pugh, A.3
-
7
-
-
0009478466
-
Enzyme-substrate complementarity and the use of binding energy in catalysis
-
New York, W. H. Freeman and Company
-
Fersht A: Enzyme-substrate complementarity and the use of binding energy in catalysis. In Enzyme Structure and Mechanism second edition. New York, W. H. Freeman and Company; 1985:311-346.
-
(1985)
Enzyme Structure and Mechanism Second Edition
, pp. 311-346
-
-
Fersht, A.1
-
8
-
-
0029128145
-
Ligand recognition properties of the Escherichia coli 4-aminobutyrate transporter encoded by gabP. Specificity of Gab permease for heterocyclic inhibitors
-
King SC, Fleming SR, Brechtel CE: Ligand recognition properties of the Escherichia coli 4-aminobutyrate transporter encoded by gabP. Specificity of Gab permease for heterocyclic inhibitors. J Biol Chem 1995, 270:19893-19897.
-
(1995)
J Biol Chem
, vol.270
, pp. 19893-19897
-
-
King, S.C.1
Fleming, S.R.2
Brechtel, C.E.3
-
9
-
-
0030044990
-
Substrate specificity of the Escherichia coli 4-aminobutyrate carrier encoded by gabP. Uptake and counterflow of structurally diverse molecules
-
Brechtel CE, Hu L, King SC: Substrate specificity of the Escherichia coli 4-aminobutyrate carrier encoded by gabP. Uptake and counterflow of structurally diverse molecules. J Biol Chem 1996, 271:783-788.
-
(1996)
J Biol Chem
, vol.271
, pp. 783-788
-
-
Brechtel, C.E.1
Hu, L.2
King, S.C.3
-
10
-
-
0032142758
-
4-Aminobutyrate (GABA) transporters from the amine-polyamine-choline superfamily: Substrate specificity and ligand recognition profile of the 4-aminobutyrate permease from Bacillus subtilis
-
Brechtel CE, King SC: 4-Aminobutyrate (GABA) transporters from the amine-polyamine-choline superfamily: substrate specificity and ligand recognition profile of the 4-aminobutyrate permease from Bacillus subtilis. Biochem J 1998, 333:565-571.
-
(1998)
Biochem J
, vol.333
, pp. 565-571
-
-
Brechtel, C.E.1
King, S.C.2
-
11
-
-
0037022683
-
Network of coupled promoting motions in enzyme catalysis
-
Agarwal PK, Billeter SR, Rajagopalan PT, Benkovic SJ, Hammes-Schiffer S: Network of coupled promoting motions in enzyme catalysis. Proc Natl Acad Sci U S A 2002, 99:2794-2799.
-
(2002)
Proc Natl Acad Sci U S A
, vol.99
, pp. 2794-2799
-
-
Agarwal, P.K.1
Billeter, S.R.2
Rajagopalan, P.T.3
Benkovic, S.J.4
Hammes-Schiffer, S.5
-
12
-
-
0035928796
-
Backbone dynamics in dihydrofolate reductase complexes: Role of loop flexibility in the catalytic mechanism
-
Osborne MJ, Schnell J, Benkovic SJ, Dyson HJ, Wright PE: Backbone dynamics in dihydrofolate reductase complexes: role of loop flexibility in the catalytic mechanism. Biochemistry 2001, 40:9846-9859.
-
(2001)
Biochemistry
, vol.40
, pp. 9846-9859
-
-
Osborne, M.J.1
Schnell, J.2
Benkovic, S.J.3
Dyson, H.J.4
Wright, P.E.5
-
13
-
-
0035969953
-
Interloop contacts modulate ligand cycling during catalysis by Escherichia coli dihydrofolate reductase
-
Miller GP, Wahnon DC, Benkovic SJ: Interloop contacts modulate ligand cycling during catalysis by Escherichia coli dihydrofolate reductase. Biochemistry 2001, 40:867-875.
-
(2001)
Biochemistry
, vol.40
, pp. 867-875
-
-
Miller, G.P.1
Wahnon, D.C.2
Benkovic, S.J.3
-
14
-
-
0037159205
-
Coupling interactions of distal residues enhance dihydrofolate reductase catalysis: Mutational effects on hydride transfer rates
-
Rajagopalan PT, Lutz S, Benkovic SJ: Coupling interactions of distal residues enhance dihydrofolate reductase catalysis: mutational effects on hydride transfer rates. Biochemistry 2002, 41:12618-12628.
-
(2002)
Biochemistry
, vol.41
, pp. 12618-12628
-
-
Rajagopalan, P.T.1
Lutz, S.2
Benkovic, S.J.3
-
15
-
-
0033593453
-
Redesigning the substrate specificity of an enzyme by cumulative effects of the mutations of non-active site residues
-
Oue S, Okamoto A, Yano T, Kagamiyama H: Redesigning the substrate specificity of an enzyme by cumulative effects of the mutations of non-active site residues. J Biol Chem 1999, 274:2344-2349.
-
(1999)
J Biol Chem
, vol.274
, pp. 2344-2349
-
-
Oue, S.1
Okamoto, A.2
Yano, T.3
Kagamiyama, H.4
-
16
-
-
0035148603
-
A (13)C NMR study on [3-(13)C]-, [1-(13)C]Ala-, or [1-(13)C]Val-labeled transmembrane peptides of bacteriorhodopsin in lipid bilayers: Insertion, rigid-body motions, and local conformational fluctuations at ambient temperature
-
Kimura S, Naito A, Tuzi S, Saito H: A (13)C NMR study on [3-(13)C]-, [1-(13)C]Ala-, or [1-(13)C]Val-labeled transmembrane peptides of bacteriorhodopsin in lipid bilayers: insertion, rigid-body motions, and local conformational fluctuations at ambient temperature. Biopolymers 2001, 58:78-88.
-
(2001)
Biopolymers
, vol.58
, pp. 78-88
-
-
Kimura, S.1
Naito, A.2
Tuzi, S.3
Saito, H.4
-
17
-
-
0029907599
-
Requirement of rigid-body motion of transmembrane helices for light activation of rhodopsin
-
Farrens DL, Altenbach C, Yang K, Hubbell WL, Khorana HG: Requirement of rigid-body motion of transmembrane helices for light activation of rhodopsin. Science 1996, 274:768-770.
-
(1996)
Science
, vol.274
, pp. 768-770
-
-
Farrens, D.L.1
Altenbach, C.2
Yang, K.3
Hubbell, W.L.4
Khorana, H.G.5
-
18
-
-
0041489951
-
Structure and mechanism of the glycerol-3-phosphate transporter from Escherichia coli
-
Huang Y, Lemieux MJ, Song J, Auer M, Wang DN: Structure and mechanism of the glycerol-3-phosphate transporter from Escherichia coli. Science 2003, 301:616-620.
-
(2003)
Science
, vol.301
, pp. 616-620
-
-
Huang, Y.1
Lemieux, M.J.2
Song, J.3
Auer, M.4
Wang, D.N.5
-
19
-
-
0041353145
-
Structure and mechanism of the lactose permease of Escherichia coli
-
Abramson J, Smirnova I, Kasho V, Verner G, Kaback HR, Iwata S: Structure and mechanism of the lactose permease of Escherichia coli. Science 2003, 301:610-615.
-
(2003)
Science
, vol.301
, pp. 610-615
-
-
Abramson, J.1
Smirnova, I.2
Kasho, V.3
Verner, G.4
Kaback, H.R.5
Iwata, S.6
-
20
-
-
2742579818
-
Simple model for the chemical potential change of a transported ion in active transport
-
Tanford C: Simple model for the chemical potential change of a transported ion in active transport. Proc Natl Acad Sci USA 1982, 79:2882-2884.
-
(1982)
Proc Natl Acad Sci USA
, vol.79
, pp. 2882-2884
-
-
Tanford, C.1
-
21
-
-
0348100913
-
Chemical potential of bound ligand, an important parameter for free energy transduction
-
Tanford C: Chemical potential of bound ligand, an important parameter for free energy transduction. Proc Natl Acad Sci USA 1981, 78:270-273.
-
(1981)
Proc Natl Acad Sci USA
, vol.78
, pp. 270-273
-
-
Tanford, C.1
-
22
-
-
0025185116
-
Toward understanding the structural basis of "forbidden" transport pathways in the Escerichia coli lactose carrier: Mutations probing the energy barriers to uncoupled transport
-
King SC, Wilson TH: Toward understanding the structural basis of "forbidden" transport pathways in the Escerichia coli lactose carrier: mutations probing the energy barriers to uncoupled transport. Mol Microbiol 1990, 4:1433-1438.
-
(1990)
Mol Microbiol
, vol.4
, pp. 1433-1438
-
-
King, S.C.1
Wilson, T.H.2
-
23
-
-
0032199006
-
Binding, gating, affinity and efficacy: The interpretation of structure-activity relationships for agonists and of the effects of mutating receptors
-
Colquhoun D: Binding, gating, affinity and efficacy: the interpretation of structure-activity relationships for agonists and of the effects of mutating receptors. Br J Pharmacol 1998, 125:924-947.
-
(1998)
Br J Pharmacol
, vol.125
, pp. 924-947
-
-
Colquhoun, D.1
-
24
-
-
0032031494
-
Functional sensitivity of polar surfaces on transmembrane helix 8 and cytoplasmic loop 8-9 of the Escherichia coli GABA (4-aminobutyrate) transporter encoded by gabP: Mutagenic analysis of a consensus amphipathic region found in transporters from bacteria to mammals
-
Hu LA, King SC: Functional sensitivity of polar surfaces on transmembrane helix 8 and cytoplasmic loop 8-9 of the Escherichia coli GABA (4-aminobutyrate) transporter encoded by gabP: mutagenic analysis of a consensus amphipathic region found in transporters from bacteria to mammals. Biochem J 1998, 330:771-776.
-
(1998)
Biochem J
, vol.330
, pp. 771-776
-
-
Hu, L.A.1
King, S.C.2
-
25
-
-
0032493639
-
Functional significance of the "signature cysteine" in helix 8 of the Escherichia coli 4-aminobutyrate transporter from the amine-polyamine-choline superfamily: Restoration of Cys-300 to the Cys-less GabP
-
Hu LA, King SC: Functional significance of the "signature cysteine" in helix 8 of the Escherichia coli 4-aminobutyrate transporter from the amine-polyamine-choline superfamily: Restoration of Cys-300 to the Cys-less GabP. J Biol Chem 1998, 273:20162-20167.
-
(1998)
J Biol Chem
, vol.273
, pp. 20162-20167
-
-
Hu, L.A.1
King, S.C.2
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