Antioxidant and NO-scavenging activities of Acanthopanax senticosus var. subinermis leaf extracts prepared using ethanol and extrusion processing

Food Science and Biotechnology

Volumn 18, Issue 5, 2009, Pages 1124-1131

  Lee, Sung Hee ^a   Oh, Hea Young ^a   Leem, Jae Yoon ^b   Yoon, Sun ^a  

^a Yonsei University   (South Korea)

^b Woosuk University   (South Korea)

Author keywords

Acanthopanax senticosus var. subinermis; Antioxidant; Extrusion; Inducible nitric oxide synthase; Nitric oxide

Indexed keywords

ACANTHOPANAX SENTICOSUS VAR. SUBINERMIS; ANTI-INFLAMMATORY ACTIVITY; ANTIOXIDANT; ANTIOXIDANT ACTIVITIES; CELL VIABILITY; DOWN-REGULATION; EAST ASIA; EXTRACTION METHOD; EXTRUSION PROCESS; EXTRUSION PROCESSING; INDUCIBLE NITRIC OXIDE SYNTHASE; INTERLEUKIN1; LEAF EXTRACTS; LIPOPOLYSACCHARIDES; MACROPHAGE CELLS; PROINFLAMMATORY CYTOKINES; RADICAL SCAVENGING ACTIVITY; SCAVENGING ACTIVITIES; SYNTHASES; TUMOR NECROSIS FACTORS; ULTRAHIGH PRESSURE;

ETHANOL; EXTRUSION; MACROPHAGES; NITRIC OXIDE; VALUE ENGINEERING;

SOLVENT EXTRACTION;

ELEUTHEROCOCCUS SENTICOSUS;

EID: 79954623881     PISSN: 12267708     EISSN: None     Source Type: Journal    
DOI: None     Document Type: Article

References (50)

1. Lee SH, Kim BK, Cho SH, Shin KH. Phytochemical constituents from the fruits of Acanthopnax sessiliflorus. Pharm. Res. Bull. 25: 280-284 (2002)
2. Han SB, Yoon YD, Ahn HJ, Lee HS, Lee CW, Yoon WK, Park SK, Kim HM. Toll-like receptor-mediated activation of B cells and macrophages by polysaccharide isolated from cell culture of Acanthopanax senticosus. Int. Immunopharmacol. 3: 1301-1312 (2003)
3. Jung HJ, Park HJ, Kim RG, Shin KM, Ha J, Choi JW, Kim HJ, Lee YS, Lee KT. In vivo anti-inflammatory and antinociceptive effects of liriodendrin isolated from the stem bark of Acanthopanax senticosus. Planta Med. 69: 610-616 (2003)
4. Jung SM, Schumacher HR, Kim H, Kim M, Lee SH, Pessler F. Reduction of urate crystal-induced inflammation by root extracts from traditional oriental medicinal plants: Elevation of prostaglandin D2 levels. Arthritis Res. Ther. 9: R64 (2007)
5. Lee S, Son D, Ryu J, Lee YS, Jung SH, Kang J, Lee SY, Kim HS, Shin KH. Anti-oxidant activities of Acanthopanax senticosus stems and their lignan components. Arch. Pharm Res. 27: 106-110 (2004)
6. Kim HY, Kim K. Protein glycation inhibitory and antioxidative activities of some plant extracts in vitro. J. Agr. Food Chem. 51: 1586-1591 (2003)
7. Xi M, Hai C, Tang H, Chen M, Fang K, Liang X. Antioxidant and antiglycation properties of total saponins extracted from traditional Chinese medicine used to treat diabetes mellitus. Phytother. Res. 22: 228-237 (2008)
8. Park SH, Lee SG, Kang SK, Chung SH. Acanthopanax senticosus reverses fatty liver disease and hyperglycemia in ob/ob mice. Arch. Pharm. Res. 29: 768-776 (2006)
9. Lee S, Shin DS, Oh KB, Shin KH. Antibacterial compounds from the leaves of Acanthopanax senticosus. Arch. Pharm Res. 26: 40-42 (2003)
10. Deyama T, Nishibe S, Nakazawa Y. Constituents and pharmacological effects of Eucommia and Siberian ginseng. Acta Pharmacol. Sin. 22: 1057-1070 (2001)
11. Apers S, Naessens T, Van Miert S, Pieters L, Vlietinck A. Quality control of roots of Eleutherococcus senticosus by HPLC. Phytochem. Anal. 16: 55-60 (2005)
12. Kimura Y, Sumiyoshi M. Effects of various Eleutherococcus senticosus cortex on swimming time, natural killer activity, and corticosterone level in forced swimming stressed mice. J. Ethnopharmacol. 95: 447-453 (2004)
13. Bae EA, Yook OJ, Chang SY, Nohara T, Kim DH. Metabolism of chiisanoside from Acanthopanax divaricatus var. albeofructus by human intestinal bacteria and its relation to some biological activities. Biol. Pharm. Bull. 24: 582-585 (2001)
14. Jung HJ, Nam JH, Choi JW, Lee KT, Park HJ, Antiinflammatory effects of chiisanoside and chiisanogenin obtained from the leaves of Acanthopanax chiisanensis in the carrageenan- and Freund's complete adjuvant-induced rats. J. Ethnopharmacol. 97: 359-367 (2005)
15. Won JH, Park SY, Nam SG, Park HJ, Choi JW, Lee KT. Inhibition of lipopolysaccharide-induced expression of inducible nitric oxide and cyclooxygenase-2 by chiisanoside via suppression of nuclear factor-κb activation in RAW 264.7 macrophage cells. Biol. Pharm. Bull. 28: 1919-1924 (2005)
16. Yi JM, Kim MS, Seo SE, Lee KN, Yook CS, Kim HM. Acanthopanax senticosus root inhibit mast cell-dependent anaphylaxis. Clin. Chim. Acta 312: 163-168 (2001)
17. Ha ES, Hwang SH, Shin KS, Yu KW, Lee KH, Choi JS, Park WM, Yoon TJ. Anti-metastatic activity of Acanthopanax senticosus extract and its possible immunological mechanism of action. J. Ethnopharmacol. 93: 247-253 (2004)
18. Lin QY, Jin LJ, Ma YS, Shi M, Xu YP. Acanthopanax senticosus inhibits nitric oxide production in murine macrophages in vitro and in vivo. Phytother. Res. 21: 879-883 (2007)
19. Lin QY, Jin LJ, Cao ZH, Lu YN, Xue HY, Xu YP. Acanthopanax senticosus suppresses reactive oxygen species production by mouse peritoneal macrophages in vitro and in vivo. Phytother. Res. 22: 740-745 (2008)
20. Lin QY, Jin LJ, Cao ZH, Xu YP. Inhibition of inducible nitric oxide synthase by Acanthopanax senticosus extract in RAW 264.7 macrophages. J. Ethnopharmacol. 118: 231-236 (2008)
21. Lim SY, Leem JY, Lee CS, Jang YJ, Park JW, Yoon S. Antioxidant and cell proliferation effects of Acanthopanax senticosus extract in human osteoblast-like MG-63 cell line. Korean J. Food Sci. Technol. 39: 694-700 (2007)
22. Tohda C, Ichimura M, Bai Y, Tanaka K, Zhu S, Komatsu K. Inhibitory effects of Eleutherococcus senticosus extracts on amyloid β (25-35)-induced neuritic atrophy and synaptic loss. J. Pharmacol. Sci. 107: 329-339 (2008)
23. Lee SH, Son DW, Ryu JY, Lee YS, Jung SH, Kang JG, Lee SY, Ki HS, Shin KH. Anti-oxidant activities of Acanthopanax senticosus stems and their lignan components. Arch. Pharm. Res. 27: 106-110 (2004)
24. Kim IH, Kim SH, Kwon JH. Optimizing the hot-water extraction conditions for Acanthopanacis cortex using response surface methodology. J. Korean Soc. Food Sci. Nutr. 37: 512-520 (2008)
25. Lim S, Leem JY, Lee C, Jang Y, Park J, Yoon S. Antioxidant and cell proliferation effects of Acanthopanax senticosus extract in human osteoblast-like MG-63 cell line. J. Korean Soc. Food Sci. Nutr. 39: 694-700 (2007)
26. Masuda T, Yonemori S, Oyama Y, Takeda T, Tanaka T, Andoh T, Sinohara A, Nakata M. Evaluation of the antioxidant activity of environmental plants: Activity of the leaf extracts from seashore plants. J. Agr. Food Chem. 47: 1749-1754 (1999)
27. Williams B, Cuvelier ME, Berset C. Use of a free radical method to evaluate antioxidant activity. LWT-Food Sci. Technol. 28: 25-30 (1995)
28. Benzie IF, Strain JJ. The ferric reducing ability of plasma (FRAP) as a measure of "antioxidant power": The FRAP assay. Anal. Biochem. 139: 70-76 (1996)
29. Tute'yan AV, Klebanoc GI, Il'ina SE, Lyubitskii OB. Comparative study of antioxidant properties of immunoregulatory peptides. B. Exp. Biol. Med+. 136: 155-158 (2003)
30. Chen TS, Liou SY, Chang YL. Antioxidant evaluation of three adaptogen extracts. Am. J. Chinese Med. 36: 1209-1217 (2008)
31. Nishible S, Kinoshita H, Takeda H, Okano G. Phenolic compounds from stem bark of Acanthopanax senticosus and their pharmacological effect in chronic swimming stressed rats. Chem. Pharm. Bull. 38: 1763-1765 (1990)
32. Li Q, Jia Y, Xu L, Wang X, Shen Z, Liu Y, Bi K. A new lignan glycoside from Eleutherococcus senticosus. Planta Med. 67: 776-778 (2001)
33. Lee S, Shin DS, Oh KB, Shin KH. Antibacterial compounds fromthe leaves of Acanthopanax senticosus. Arch. Pharm. Res. 26: 106-110 (2003)
34. Li Q, Jia Y, Xu L, Wang X, Shen Z, Liu Y, Bi K. Simultaneous determination of protocatechiuc acid, syringin, chlorogenic acid, caffeic acid, liriodendrin, and isofraxidin in Acanthopanax senticosus Harms by HPLC-DAD. Biol. Pharm. Bull. 29: 532-534 (2006)
35. Ha DC, Lee JW, Ryu GH. Change in ginsenosides and maltol in dried raw ginseng during extrusion process. Food Sci. Biotechnol. 14: 363-376 (2005)
36. Na K, Yun JM, Choi MJ, Hwang JK. Extraction of pectic polysaccharides form extruded ginseng fiber. Food Sci. Biotechnol. 13: 486-489 (2004)
37. Moncada S, Higgs A. The L-arginine-nitric oxide pathway. New Eng. J. Med. 329: 2002-2012 (1999)
38. Busse, R, Mulch A. Induction of nitric oxide synthase by cytokines in vascular smooth muscle cell. FEBS Lett. 275: 87-90 (1990)
39. Zhang X, Morrison DC. Lipopolysaccharide-induced selective priming effects on tumor necrosis factor a and nitric oxide production in mouse peritoneal macrophages. J. Exp. Med. 177: 511-516 (1993)
40. Kim MS, Kim SO, Lim WK, Lee JM, Hwang CY, Cho KH, Kim HM. Novel effects on On-Chung-Eum, the traditional plant medicine, on cytokine production in human mononuclear cells from Behçet's. Immunopharm. Immunot. 25: 65-72 (2003)
41. Amirzargar A, Khosravi F, Dianat S, Hushmand F, Maryousef P, Foroushani AR, Lotfi J, Nikbin B. Profile of cytokines gene polymorphisms in Iranian multiple sclerosis patients. Mult. Scler. 13: 253-255 (2007)
42. Hutchison S, Choo-kang BS, Bundick RV, Leishman AJ, Brewer J, Mcinnes IB, Garside P. Tumour necrosis factor-alpha blockade suppresses murine allergic airways inflammation. Clin. Exp. Immunol. 151: 114-122 (2008)
43. Laduca JR, Gaspari AA. Targeting tumor necrosis factor alpha. New drugs used to modulate inflammatory diseases. Dermatol. Clin. 19: 617-635 (2001)
44. Morgan MM, Clayton CC, Heinricher MM. Dissociation of hyperalgesia from fever following intracerebroventricular administration of interleukin-1beta in the rat. Brain Res. 1022: 96-100 (2004)
45. Laranjinha J, Alemeida L, Madeira V. Reactivity of dietary phenolic acids with peroxyl radicals: Antioxidant activity upon low-density lipoprotein peroxidation. Biochem. Pharm. 48: 487-494 (1994)
46. Ness AR, Powles JW. Fruit and vegetables, and cardiovascular disease. Inter. J. Epidemiol. 26: 1-13 (1997)
47. Meng QH, Lewis P, Wahala K, Adlercreutz H, Tikkanen MJ. Incorporation of esterified soybean isoflavones with antioxidant activity into low-density lipoprotein. Biochem. Biophys. Acta 1438: 369-376 (1999)
48. Lee YJ, Chun HY, Kwak HK, Yoon S. The effects of A. senticosus supplementation on serum lipid profiles, biomarkers of oxidative stress, and lymphocyte DNA damage in postmenopausal women. Biochem. Bioph. Res. Co. 375: 44-48 (2008)
49. Won JH, Park SY, Nam SG, Park HJ, Choi JW, Lee KT. Biologically active triterpenoid saponins from Acanthopanax senticosus. J. Nat. Prod. 69: 1577-1581 (2006)
50. Jin JL, Lee S, Lee YY, Kim JM, Heo JE, Yun-Choi HS. Platelet anti-aggregating triterpenoids from the leaves of Acanthopanax senticosus and the fruits of A. sessiliflorus. Planta Med. 70: 564-566 (2004)