Toll-like receptor-mediated activation of B cells and macrophages by polysaccharide isolated from cell culture of Acanthopanax senticosus

International Immunopharmacology

Volumn 3, Issue 9, 2003, Pages 1301-1312

  Han, S B ^a   Yoon, Y D ^a   Ahn, H J ^a   Lee, H S ^a   Lee, C W ^a   Yoon, W K ^a   Park, S K ^a   Kim, H M ^a  

^a Korea Research Institute of Bioscience and Biotechnology (KRIBB)   (South Korea)

Author keywords

B cells; Macrophages; Plant polysaccharide; Toll like receptor

Indexed keywords

ACANTHOPANAX SENTICOSUS EXTRACT; ANTIBODY; CYTOKINE; IMMUNOGLOBULIN ENHANCER BINDING PROTEIN; MITOGEN ACTIVATED PROTEIN KINASE 1; PLANT EXTRACT; POLYSACCHARIDE; STRESS ACTIVATED PROTEIN KINASE; TOLL LIKE RECEPTOR 2; TOLL LIKE RECEPTOR 4; UNCLASSIFIED DRUG;

ANIMAL CELL; ARTICLE; B LYMPHOCYTE; BINDING AFFINITY; CELL ACTIVITY; CELL CULTURE; CELL DIFFERENTIATION; CELL MEMBRANE; CELL PROLIFERATION; CONTROLLED STUDY; CYTOKINE PRODUCTION; DRUG BINDING; DRUG EFFECT; DRUG ISOLATION; DRUG MECHANISM; DRUG PENETRATION; ELEUTHEROCOCCUS SENTICOSUS; IMMUNE RESPONSE; IMMUNOMODULATION; MACROPHAGE; MEDICINAL PLANT; MOLECULAR WEIGHT; MOUSE; NONHUMAN; PLANT CELL; PRIORITY JOURNAL; PROTEIN EXPRESSION; PROTEIN FUNCTION; SIGNAL TRANSDUCTION; STATISTICAL SIGNIFICANCE; T LYMPHOCYTE;

EID: 0042703167     PISSN: 15675769     EISSN: None     Source Type: Journal    
DOI: 10.1016/S1567-5769(03)00118-8     Document Type: Article

References (33)

1. Medzhitov R., Janeway C.A. Jr. Innate immunity: the virtues of a nonclonal system of recognition. Cell. 91(3):1997;295-298.
2. Brightbill H.D., Libraty D.H., Krutzik S.R., Yang R.B., Belisle J.T.et al. Host defense mechanisms triggered by microbial lipoproteins through Toll-like receptors. Science. 285(5428):1999;732-736.
3. Imler J.L., Hoffmann J.A. Toll receptors in innate immunity. Trends Cell Biol. 11(7):2001;304-311.
4. Kobayashi K., Hernandez L.D., Galan J.E., Janeway C.A. Jr., Medzhitov R.et al. IRAK-M is a negative regulator of Toll-like receptor signaling. Cell. 110(2):2002;191-202.
5. Rehli M. Of mice and men: species variations of Toll-like receptor expression. Trends Immunol. 23(8):2002;375-378.
6. Kawai T., Adachi O., Ogawa T., Takeda K., Akira S. Unresponsiveness of MyD88-deficient mice to endotoxin. Immunity. 11(1):1999;115-122.
7. Medzhitov R., Preston-Hurlburt P., Kopp E., Stadlen A., Chen C.et al. MyD88 is an adaptor protein in the hToll/IL-1 receptor family signaling pathways. Mol. Cell. 2(2):1998;253-258.
8. Wesche H., Henzel W.J., Shillinglaw W., Li S., Cao Z. MyD88: an adaptor that recruits IRAK to the IL-1 receptor complex. Immunity. 7(6):1997;837-847.
9. Zhang F.X., Kirschning C.J., Mancinelli R., Xu X.P., Jin Y.et al. Bacterial lipopolysaccharide activates nuclear factor-kappa B through interleukin-1 signaling mediators in cultured human dermal endothelial cells and mononuclear phagocytes. J. Biol. Chem. 274(12):1999;7611-7614.
10. Ogata H., Su I., Miyake K., Nagai Y., Akashi S.et al. The toll-like receptor protein RP105 regulates lipopolysaccharide signaling in B cells. J. Exp. Med. 192(1):2000;23-29.
11. Akashi S., Shimazu R., Ogata H., Nagai Y., Takeda K.et al. Cutting edge: cell surface expression and lipopolysaccharide signaling via the toll-like receptor 4-MD-2 complex on mouse peritoneal macrophages. J. Immunol. 164(7):2000;3471-3475.
12. Borchers A.T., Stern J.S., Hackman R.M., Keen C.L., Gershwin M.E. Mushrooms, tumors, and immunity. Proc. Soc. Exp. Biol. Med. 221(4):1999;281-293.
13. Ooi V.E., Liu F. Immunomodulation and anti-cancer activity of polysaccharide-protein complexes. Curr. Med. Chem. 7(7):2000;715-729.
14. Jeon Y.J., Kim H.M. Experimental evidences and signal transduction pathways involved in the activation of NF-kappa B/Rel by angelan in murine macrophages. Int. Immunopharmacol. 1(7):2001;1331-1339.
15. Han S.B., Lee C.W., Jeon Y.J., Hong N.D., Yoo I.D.et al. The inhibitory effect of polysaccharides isolated from Phellinus linteus on tumor growth and metastasis. Immunopharmacology. 41(2):1999;157-164.
16. Han S.B., Park S.H., Lee K.H., Lee C.W., Lee S.H.et al. Polysaccharide isolated from the radix of Platycodon grandiflorum selectively activates B cells and macrophages but not T cells. Int. Immunopharmacol. 1(11):2001;1969-1978.
17. Kang J.S., Linh P.T., Cai X.F., Kim H.S., Lee J.J.et al. Quantitative determination of eleutheroside B and E from Acanthopanax species by high performance liquid chromatography. Arch. Pharm. Res. 24(5):2001;407-411.
18. Park S.Y., Chang S.Y., Yook C.S., Nohara T. New 3,4-seco-lupane-type triterpene glycosides from Acanthopanax senticosus forma inermis. J. Nat. Prod. 63(12):2000;1630-1633.
19. Yi J.M., Hong S.H., Kim J.H., Kim H.K., Song H.J.et al. Effect of Acanthopanax senticosus stem on mast cell-dependent anaphylaxis. J. Ethnopharmacol. 79(3):2002;347-352.
20. Yi J.M., Kim M.S., Seo S.W., Lee K.N., Yook C.S.et al. Acanthopanax senticosus root inhibits mast cell-dependent anaphylaxis. Clin. Chim. Acta. 312(1-2):2001;163-168.
21. Shen M.L., Zhai S.K., Chen H.L., Luo Y.D., Tu G.R.et al. Immunomopharmacological effects of polysaccharides from Acanthopanax senticosus on experimental animals. Int. J. Immunopharmacol. 13(5):1991;549-554.
22. Han S.B., Park S.H., Jeon Y.J., Kim Y.K., Kim H.M.et al. Prodigiosin blocks T cell activation by inhibiting interleukin-2R alpha expression and delays progression of autoimmune diabetes and collagen-induced arthritis. J. Pharmacol. Exp. Ther. 299(2):2001;415-425.
23. Morrison D.C., Jacobs D.M. Binding of polymyxin B to the lipid A portion of bacterial lipopolysaccharides. Immunochemistry. 13(10):1976;813-818.
24. Ninomiya-Tsuji J., Kishimoto K., Kiyama A., Inoue J., Cao Z., Mataumoto K. The kinase TAK1 can activate the NIK-IkB as well as the MAP kinase cascade in the IL-1 signaling pathway. Nature. 398(6724):1999;252.
25. Maeda Y.Y., Chihara G. Lentinan, a new immuno-accelerator of cell-mediated responses. Nature. 229(5287):1971;634.
26. Haba S., Hamaoka T., Takatsu K., Kitagawa M. Selective suppression of T-cell activity in tumor-bearing mice and its improvement by lentinan, a potent anti-tumor polysaccharide. Int. J. Cancer. 18(1):1976;93-104.
27. Maeda Y.Y., Watanabe S.T., Chihara C., Rokutanda M. Denaturation and renaturation of a beta-1,6;1,3-glucan, lentinan, associated with expression of T-cell-mediated responses. Cancer Res. 48(3):1988;671-675.
28. Suzuki M., Iwashiro M., Takatsuki F., Kuribayashi K., Hamuro J. Reconstitution of anti-tumor effects of lentinan in nude mice: roles of delayed-type hypersensitivity reaction triggered by CD4-positive T cell clone in the infiltration of effector cells into tumor. Jpn. J. Cancer Res. 85(4):1994;409-417.
29. Figueras A., Santarem M.M., Novoa B. Influence of the sequence of administration of beta-glucans and a Vibrio damsela vaccine on the immune response of turbot (Scophthalmus maximus L.). Vet. Immunol. Immunopathol. 64(1):1998;59-68.
30. Song K.S., Cho S.M., Lee J.H., Kim H.M., Han S.B.et al. B-lymphocyte-stimulating polysaccharide from mushroom Phellinus linteus. Chem. Pharm. Bull. (Tokyo). 43(12):1995;2105-2108.
31. Kim H.M., Han S.B., Oh G.T., Kim Y.H., Hong D.H.et al. Stimulation of humoral and cell mediated immunity by polysaccharide from mushroom Phellinus linteus. Int. J. Immunopharmacol. 18(5):1996;295-303.
32. Modlin R.L. Mammalian toll-like receptors. Ann. Allergy, Asthma, & Immun. 88(6):2002;543-547. [quiz 48-50, 83].
33. Lehner M.D., Morath S., Michelsen K.S., Schumann R.R., Hartung T. Induction of cross-tolerance by lipopolysaccharide and highly purified lipoteichoic acid via different Toll-like receptors independent of paracrine mediators. J. Immunol. 166(8):2001;5161-5167.