Cellular and molecular effects of the liposomal mTHPC derivative Foslipos in prostate carcinoma cells in vitro

Photodiagnosis and Photodynamic Therapy

Volumn 8, Issue 2, 2011, Pages 86-96

  Gyenge, Emina Besic ^a   Hiestand, Seraina ^a   Graefe, Susanna ^b   Walt, Heinrich ^c   Maake, Caroline ^a  

^a UNIVERSITY OF ZURICH   (Switzerland)

^b Biolitec AG   (Germany)

^c UNIVERSITY HOSPITAL ZURICH   (Switzerland)

Author keywords

Cell line; Nucleic acids; Photodynamic therapy; Photosensitizer; Prostate cancer

Indexed keywords

ALPHA B CRYSTALLIN; ALPHA CRYSTALLIN; CATALASE; COPPER ZINC SUPEROXIDE DISMUTASE; CYCLIN C; CYCLIN D1; CYCLIN G1; CYTOCHROME P450 REDUCTASE; DIMETHYLANILINE MONOOXYGENASE; DIPALMITOYLPHOSPHATIDYLCHOLINE; DIPALMITOYLPHOSPHATIDYLGLYCEROL; FLAVIN CONTAINING MONOOXYGENASE 5; FOSLIPOS; GLUTATHIONE REDUCTASE; GLUTATHIONE TRANSFERASE M3; HEAT SHOCK 10KDA PROTEIN 1; HEAT SHOCK 60KDA PROTEIN 1; HEAT SHOCK 70KDA PROTEIN 1; HEAT SHOCK 70KDA PROTEIN 1 LIKE; HEAT SHOCK 70KDA PROTEIN 1A; HEAT SHOCK 70KDA PROTEIN 2; HEAT SHOCK 70KDA PROTEIN 4; HEAT SHOCK 70KDA PROTEIN 5; HEAT SHOCK 70KDA PROTEIN 6; HEAT SHOCK 90KDA PROTEIN ALPHA CLASS B MEMBER 1; HEME OXYGENASE 1; MANGANESE SUPEROXIDE DISMUTASE; PEROXIREDOXIN 2; PHOTOSENSITIZING AGENT; TRANSCRIPTION FACTOR E2F1; UNCLASSIFIED DRUG;

APOPTOSIS; ARTICLE; CANCER INHIBITION; CARCINOGENESIS; CARCINOMA CELL; CELL COUNT; CELL DEATH; CELL PROLIFERATION; CONTROLLED STUDY; DNA DAMAGE; DNA REPAIR; DRUG MECHANISM; GENE EXPRESSION; GENE EXPRESSION PROFILING; HEAT SHOCK; HUMAN; HUMAN CELL; ILLUMINATION; IN VITRO STUDY; INFLAMMATION; LIPOSOMAL DELIVERY; METABOLIC STRESS; NUCLEIC ACID ANALYSIS; OXIDATIVE STRESS; PHOTODYNAMIC THERAPY; PHOTODYNAMICS; POLYMERASE CHAIN REACTION; PRIORITY JOURNAL; PROSTATE CARCINOMA;

APOPTOSIS; CELL LINE, TUMOR; CELL SURVIVAL; DNA REPAIR; DNA, NEOPLASM; GENE EXPRESSION; HUMANS; LIPOSOMES; MALE; MESOPORPHYRINS; OXIDATIVE STRESS; PHOTOCHEMOTHERAPY; PHOTOSENSITIZING AGENTS; PROSTATIC NEOPLASMS; RNA, NEOPLASM;

TETRA;

EID: 79954622181     PISSN: 15721000     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.pdpdt.2011.02.001     Document Type: Article

References (61)

1. Allison R.R., Bagnato V.S., Sibata C.H. Future of oncologic photodynamic therapy. Future Oncol 2010, 6:929-940.
2. Brown S.B., Brown E.A., Walker I. The present and future role of photodynamic therapy in cancer treatment. Lancet Oncol 2004, 5:497-508.
3. Sasnouski S., Pic E., Dumas D., et al. Influence of incubation time and sensitizer localization on meta-tetra(hydroxyphenyl)chlorin (mTHPC)-induced photoinactivation of cells. Radiat Res 2007, 168:209-217.
4. Triesscheijn M., Ruevekamp M., Out R., et al. The pharmacokinetic behavior of the photosensitizer meso-tetra-hydroxyphenyl-chlorin in mice and men. Cancer Chemother Pharmacol 2007, 60:113-122.
5. Buchholz J., Kaser-Hotz B., Khan T., et al. Optimizing photodynamic therapy: in vivo pharmacokinetics of liposomal meta-(tetrahydroxyphenyl)chlorin in feline squamous cell carcinoma. Clin Cancer Res 2005, 11:7538-7544.
6. Svensson J., Johansson A., Grafe S., et al. Tumor selectivity at short times following systemic administration of a liposomal temoporfin formulation in a murine tumor model. Photochem Photobiol 2007, 83:1211-1219.
7. Hansch A., Frey O., Gajda M., et al. Photodynamic treatment as a novel approach in the therapy of arthritic joints. Lasers Surg Med 2008, 40:265-272.
8. Lassalle H.P., Dumas D., Grafe S., D'Hallewin M.A., Guillemin F., Bezdetnaya L. Correlation between in vivo pharmacokinetics, intratumoral distribution and photodynamic efficiency of liposomal mTHPC. J Control Rel 2009, 134:118-124.
9. Kirveliene V., Sadauskaite A., Kadziauskas J., Sasnauskiene S., Juodka B. Correlation of death modes of photosensitized cells with intracellular ATP concentration. FEBS Lett 2003, 553:167-172.
10. Marchal S., Francois A., Dumas D., Guillemin F., Bezdetnaya L. Relationship between subcellular localisation of Foscan and caspase activation in photosensitised MCF-7 cells. Br J Cancer 2007, 96:944-951.
11. Bressenot A., Marchal S., Bezdetnaya L., Garrier J., Guillemin F., Plenat F. Assessment of apoptosis by immunohistochemistry to active caspase-3, active caspase-7, or cleaved PARP in monolayer cells and spheroid and subcutaneous xenografts of human carcinoma. J Histochem Cytochem 2009, 57:289-300.
12. Yow C.M., Mak N.K., Leung A.W., Huang Z. Induction of early apoptosis in human nasopharyngeal carcinoma cells by mTHPC-mediated photocytotoxicity. Photodiagnosis Photodyn Ther 2009, 6:122-127.
13. Gharehbaghi K., Kubin A., Grusch M., et al. Photodynamic action of meta-tetrahydroxyphenylchlorin (mTHPC) on an ovarian cancer cell line. Anticancer Res 2000, 20:2647-2652.
14. Sasnauskiene A., Kadziauskas J., Vezelyte N., Jonusiene V., Kirveliene V. Apoptosis, autophagy and cell cycle arrest following photodamage to mitochondrial interior. Apoptosis 2009, 14:276-286.
15. Merchant S., Sun J., Korbelik M. Dying cells program their expedient disposal: serum amyloid P component upregulation in vivo and in vitro induced by photodynamic therapy of cancer. Photochem Photobiol Sci 2007, 6:1284-1289.
16. Mitra S., Goren E.M., Frelinger J.G., Foster T.H. Activation of heat shock protein 70 promoter with meso-tetrahydroxyphenyl chlorin photodynamic therapy reported by green fluorescent protein in vitro and in vivo. Photochem Photobiol 2003, 78:615-622.
17. Schouwink H., Oppelaar H., Ruevekamp M., et al. Oxygen depletion during and after mTHPC-mediated photodynamic therapy in RIF1 and H-MESO1 tumors. Radiat Res 2003, 159:190-198.
18. Sharwani A., Jerjes W., Hopper C., et al. Photodynamic therapy down-regulates the invasion promoting factors in human oral cancer. Arch Oral Biol 2006, 51:1104-1111.
19. Yom S.S., Busch T.M., Friedberg J.S., et al. Elevated serum cytokine levels in mesothelioma patients who have undergone pleurectomy or extrapleural pneumonectomy and adjuvant intraoperative photodynamic therapy. Photochem Photobiol 2003, 78:75-81.
20. Muller S., Walt H., Dobler-Girdziunaite D., Fiedler D., Haller U. Enhanced photodynamic effects using fractionated laser light. J Photochem Photobiol B 1998, 42:67-70.
21. Bombelli C., Caracciolo G., Di Profio P., et al. Inclusion of a photosensitizer in liposomes formed by DMPC/gemini surfactant: correlation between physicochemical and biological features of the complexes. J Med Chem 2005, 48:4882-4891.
22. Pegaz B., Debefve E., Ballini J.P., et al. Photothrombic activity of m-THPC-loaded liposomal formulations: pre-clinical assessment on chick chorioallantoic membrane model. Eur J Pharm Sci 2006, 28:134-140.
23. D'Hallewin M.A., Kochetkov D., Viry-Babel Y., et al. Photodynamic therapy with intratumoral administration of lipid-based mTHPC in a model of breast cancer recurrence. Lasers Surg Med 2008, 40:543-549.
24. Dragicevic-Curic N., Scheglmann D., Albrecht V., Fahr A. Temoporfin-loaded invasomes: development, characterization and in vitro skin penetration studies. J Control Rel 2008, 127:59-69.
25. Teiten M.H., Bezdetnaya L., Merlin J.L., et al. Effect of meta-tetra(hydroxyphenyl)chlorin (mTHPC)-mediated photodynamic therapy on sensitive and multidrug-resistant human breast cancer cells. J Photochem Photobiol B 2001, 62:146-152.
26. Leung W.N., Sun X., Mak N.K., Yow C.M. Photodynamic effects of mTHPC on human colon adenocarcinoma cells: photocytotoxicity, subcellular localization and apoptosis. Photochem Photobiol 2002, 75:406-411.
27. Kiesslich T., Berlanda J., Plaetzer K., Krammer B., Berr F. Comparative characterization of the efficiency and cellular pharmacokinetics of Foscan- and Foslip-based photodynamic treatment in human biliary tract cancer cell lines. Photochem Photobiol Sci 2007, 6:619-627.
28. Sehgal I., Sibrian-Vazquez M., Vicente M.G. Photoinduced cytotoxicity and biodistribution of prostate cancer cell-targeted porphyrins. J Med Chem 2008, 51:6014-6020.
29. Foster T.H., Pearson B.D., Mitra S., Bigelow C.E. Fluorescence anisotropy imaging reveals localization of meso-tetrahydroxyphenyl chlorin in the nuclear envelope. Photochem Photobiol 2005, 81:1544-1547.
30. Rousset N., Keminon E., Eleouet S., et al. Use of alkaline Comet assay to assess DNA repair after m-THPC-PDT. J Photochem Photobiol B 2000, 56:118-131.
31. Ricci F., Pucci S., Sesti F., Missiroli F., Cerulli L., Spagnoli L.G. Modulation of Ku70/80, clusterin/ApoJ isoforms and Bax expression in indocyanine-green-mediated photo-oxidative cell damage. Ophthalmic Res 2007, 39:164-173.
32. Yang Z.Z., Li M.X., Zhang Y.S., et al. Knock down of the dual functional protein apurinic/apyrimidinic endonuclease 1 enhances the killing effect of hematoporphrphyrin derivative-mediated photodynamic therapy on non-small cell lung cancer cells in vitro and in a xenograft model. Cancer Sci 2009.
33. Akramiene D., Aleksandraviciene C., Grazeliene G., et al. Potentiating effect of beta-glucans on photodynamic therapy of implanted cancer cells in mice. Tohoku J Exp Med 2010, 220:299-306.
34. McNair F.I., Marples B., West C.M., Moore J.V. A comet assay of DNA damage and repair in K562 cells after photodynamic therapy using haematoporphyrin derivative, methylene blue and meso-tetrahydroxyphenylchlorin. Br J Cancer 1997, 75:1721-1729.
35. Yow C.M., Chen J.Y., Mak N.K., Cheung N.H., Leung A.W. Cellular uptake, subcellular localization and photodamaging effect of temoporfin (mTHPC) in nasopharyngeal carcinoma cells: comparison with hematoporphyrin derivative. Cancer Lett 2000, 157:123-131.
36. Du H.Y., Olivo M., Tan B.K., Bay B.H. Photoactivation of hypericin down-regulates glutathione S-transferase activity in nasopharyngeal cancer cells. Cancer Lett 2004, 207:175-181.
37. Luo J., Li L., Zhang Y., et al. Inactivation of primary antioxidant enzymes in mouse keratinocytes by photodynamically generated singlet oxygen. Antioxid Redox Signal 2006, 8:1307-1314.
38. El-Missiry M.A., Abou-Seif M. Photosensitization induced reactive oxygen species and oxidative damage in human erythrocytes. Cancer Lett 2000, 158:155-163.
39. Krusekopf S., Roots I. St. John's wort and its constituent hyperforin concordantly regulate expression of genes encoding enzymes involved in basic cellular pathways. Pharmacogenet Genomics 2005, 15:817-829.
40. Hirakawa K., Mori M., Yoshida M., Oikawa S., Kawanishi S. Photo-irradiated titanium dioxide catalyzes site specific DNA damage via generation of hydrogen peroxide. Free Radic Res 2004, 38:439-447.
41. Chekulayeva L.V., Shevchuk I.N., Chekulayev V.A., Ilmarinen K. Hydrogen peroxide, superoxide, and hydroxyl radicals are involved in the phototoxic action of hematoporphyrin derivative against tumor cells. J Environ Pathol Toxicol Oncol 2006, 25:51-77.
42. Golab J., Nowis D., Skrzycki M., et al. Antitumor effects of photodynamic therapy are potentiated by 2-methoxyestradiol. A superoxide dismutase inhibitor. J Biol Chem 2003, 278:407-414.
43. Nowis D., Legat M., Grzela T., et al. Heme oxygenase-1 protects tumor cells against photodynamic therapy-mediated cytotoxicity. Oncogene 2006, 25:3365-3374.
44. Frank J., Lornejad-Schafer M.R., Schoffl H., Flaccus A., Lambert C., Biesalski H.K. Inhibition of heme oxygenase-1 increases responsiveness of melanoma cells to ALA-based photodynamic therapy. Int J Oncol 2007, 31:1539-1545.
45. Parcellier A., Schmitt E., Brunet M., Hammann A., Solary E., Garrido C. Small heat shock proteins HSP27 and alphaB-crystallin: cytoprotective and oncogenic functions. Antioxid Redox Signal 2005, 7:404-413.
46. Kocanova S., Buytaert E., Matroule J.Y., et al. Induction of heme-oxygenase 1 requires the p38MAPK and PI3K pathways and suppresses apoptotic cell death following hypericin-mediated photodynamic therapy. Apoptosis 2007, 12:731-741.
47. Hanlon J.G., Adams K., Rainbow A.J., Gupta R.S., Singh G. Induction of Hsp60 by photofrin-mediated photodynamic therapy. J Photochem Photobiol B 2001, 64:55-61.
48. Verwanger T., Sanovic R., Aberger F., Frischauf A.M., Krammer B. Gene expression pattern following photodynamic treatment of the carcinoma cell line A-431 analysed by cDNA arrays. Int J Oncol 2002, 21:1353-1359.
49. Jalili A., Makowski M., Switaj T., et al. Effective photoimmunotherapy of murine colon carcinoma induced by the combination of photodynamic therapy and dendritic cells. Clin Cancer Res 2004, 10:4498-4508.
50. Kuzelova K., Grebenova D., Pluskalova M., Marinov I., Hrkal Z. Early apoptotic features of K562 cell death induced by 5-aminolaevulinic acid-based photodynamic therapy. J Photochem Photobiol B 2004, 73:67-78.
51. Yanase S., Nomura J., Matsumura Y., et al. Enhancement of the effect of 5-aminolevulinic acid-based photodynamic therapy by simultaneous hyperthermia. Int J Oncol 2005, 27:193-201.
52. Prasmickaite L., Cekaite L., Hellum M., Hovig E., Hogset A., Berg K. Transcriptome changes in a colon adenocarcinoma cell line in response to photochemical treatment as used in photochemical internalisation (PCI). FEBS Lett 2006, 580:5739-5746.
53. Sugiyama M., Sakahara H., Sato K., et al. Evaluation of 3′-deoxy-3′-18F-fluorothymidine for monitoring tumor response to radiotherapy and photodynamic therapy in mice. J Nucl Med 2004, 45:1754-1758.
54. Romanko Y.S., Tsyb A.F., Kaplan M.A., Popuchiev V.V. Relationship between antitumor efficiency of photodynamic therapy with photoditasine and photoenergy density. Bull Exp Biol Med 2005, 139:460-464.
55. Togashi H., Uehara M., Ikeda H., Inokuchi T. Fractionated photodynamic therapy for a human oral squamous cell carcinoma xenograft. Oral Oncol 2006, 42:526-532.
56. Park C., Lee I., Kang W.K. Lovastatin-induced E2F-1 modulation and its effect on prostate cancer cell death. Carcinogenesis 2001, 22:1727-1731.
57. Finlan L.E., Kernohan N.M., Thomson G., Beattie P.E., Hupp T.R., Ibbotson S.H. Differential effects of 5-aminolaevulinic acid photodynamic therapy and psoralen+ultraviolet A therapy on p53 phosphorylation in normal human skin in vivo. Br J Dermatol 2005, 153:1001-1010.
58. Crescenzi E., Varriale L., Iovino M., Chiaviello A., Veneziani B.M., Palumbo G. Photodynamic therapy with indocyanine green complements and enhances low-dose cisplatin cytotoxicity in MCF-7 breast cancer cells. Mol Cancer Ther 2004, 3:537-544.
59. Lu M., Xia L., Hua H., Jing Y. Acetyl-keto-beta-boswellic acid induces apoptosis through a death receptor 5-mediated pathway in prostate cancer cells. Cancer Res 2008, 68:1180-1186.
60. Bach L.A. IGFBP-6 five years on; not so 'forgotten'?. Growth Horm IGF Res 2005, 15:185-192.
61. Koike H., Ito K., Takezawa Y., Oyama T., Yamanaka H., Suzuki K. Insulin-like growth factor binding protein-6 inhibits prostate cancer cell proliferation: implication for anticancer effect of diethylstilbestrol in hormone refractory prostate cancer. Br J Cancer 2005, 92:1538-1544.