Photo-irradiated titanium dioxide catalyzes site specific DNA damage via generation of hydrogen peroxide

Free Radical Research

Volumn 38, Issue 5, 2004, Pages 439-447

  Hirakawa, Kazutaka ^a   Mori, Masafumi ^a   Yoshida, Mami ^a   Oikawa, Shinji ^a   Kawanishi, Shosuke ^a  

^a MIE UNIVERSITY   (Japan)

Author keywords

Copper; Free hydroxyl radicals; Hydrogen; Oxidative DNA damage; Superoxide; Titanium dioxide

Indexed keywords

8 HYDROXYDEOXYGUANOSINE; ALCOHOL; CATALASE; CHELATING AGENT; COPPER; DNA; DNA FRAGMENT; DNA GLYCOSYLTRANSFERASE; FORMIC ACID; GUANINE; HYDROGEN PEROXIDE; HYDROXYL RADICAL; MANNITOL; PHOSPHORUS 32; PHOTOSENSITIZING AGENT; PIPERIDINE; PROTEIN P16; PROTEIN P53; PYRIMIDINE; SCAVENGER; SUPEROXIDE; SUPEROXIDE DISMUTASE; THYMIDINE; TITANIUM DIOXIDE;

ARTICLE; CONTROLLED STUDY; CYTOTOXICITY; DNA CLEAVAGE; DNA DAMAGE; ESCHERICHIA COLI; HUMAN; HUMAN CELL; INHIBITION KINETICS; LIGHT; PHOTOCATALYSIS; PHOTODYNAMIC THERAPY;

CATALASE; COPPER; CYCLIN-DEPENDENT KINASE INHIBITOR P16; DNA DAMAGE; DNA-FORMAMIDOPYRIMIDINE GLYCOSYLASE; ESCHERICHIA COLI; FREE RADICAL SCAVENGERS; GENES, RAS; HUMANS; HYDROGEN PEROXIDE; HYDROXYL RADICAL; LIGHT; PHENANTHROLINES; PHOTOSENSITIZING AGENTS; SUPEROXIDE DISMUTASE; SUPEROXIDES; TITANIUM; TUMOR SUPPRESSOR PROTEIN P53; WATER POLLUTANTS, CHEMICAL;

LETHRINIDAE;

EID: 2442478632     PISSN: 10715762     EISSN: None     Source Type: Journal    
DOI: 10.1080/1071576042000206487     Document Type: Article

References (44)

1. Fujishima, A., Rao, T.N. and Tryk, D.A. (2000) "Titanium dioxide photoatalysis", J. Photochem. Photobiol. C Photochem. Rev. 1, 1-21.
2. Konaka, R., Kasahara, E., Dunlap, W.C., Yamamoto, Y., Chien, K.C. and Inoue, M. (1999) "Irradiation of titanium dioxide generates both singlet oxygen and superoxide anion", Free Radic. Biol. Med. 27, 294-300.
3. Konaka, R., Kasahara, E., Dunlap, W.C., Yamamoto, Y., Chien, K.C. and Inoue, M. (2001) "Ultraviolet irradiation of titanium dioxide in aqueous dispersion generates singlet oxygen", Redox Rep. 6, 319-325.
4. 2 thin films: dynamic view of the active oxygen species responsible for the effect", J. Photochem. Photobiol. A Chem. 106, 51-56.
5. 2 thin film photocatalysts", Environ. Sci. Technol. 32, 726-728.
6. 2 photocatalyst on selected food-borne pathogenic bacteria", Chemosphere 52, 277-281.
7. 2 powder", Bull. Chem. Soc. Jpn. 64, 1268-1273.
8. 2 with the aid of superoxide dismutase", Chem. Lett., 427-430.
9. 2 semiconducting microelectrode under irradiation", Chem. Lett., 185-186.
10. 2 particles", Cancer Res. 52, 2346-2348.
11. Ackroyd, R., Kelty, C., Brown, N. and Reed, M. (2001) "The history of photodetection and photodynamic therapy", Photochem. Photobiol. 74, 656-669.
12. Wamer, W.G., Yin, J.J. and Wei, R.R. (1997) "Oxidative damage to nucleic acids photosensitized by titanium dioxide", Free Radic. Biol. Med. 23, 851-858.
13. 2 on mutans streptococci", J. Photochem. Photobiol. B 14, 369-379.
14. Dunford, R., Salinaro, A., Cai, L., Serpone, N., Horikoshi, S., Hidaka, H. and Knowland, J. (1997) "Chemical oxidation and DNA damage catalysed by inorganic sunscreen ingredients", FEBS Lett. 418, 87-90.
15. Nakagawa, Y., Wakuri, S., Sakamoto, K. and Tanaka, N. (1997) "The photogenotoxicity of titanium dioxide particles", Mutat. Res. 394, 125-132.
16. Kashige, N., Kakita, Y., Nakashima, Y., Miake, F. and Watanabe, K. (2001) "Mechanism of the photocatalytic inactivation of Lactobacillus casei phage PL-1 by titania thin film", Curr. Microbiol. 42, 184-189.
17. Chumakov, P. (1990) EMBL Data Library, accession number X54156.
18. Serrano, M., Hannon, G.J. and Beach, D.A. (1993) "A new regulatory motif in cell-cycle control causing specific inhibition of cyclin D/CDK4", Nature 366, 704-707.
19. Capon, D.J., Chen, E.Y., Levinson, A.D., Seeburg, P.H. and Goeddel, D.V. (1983) "Complete nucleotide sequences of the T24 human bladder carcinoma oncogene and its normal homologue", Nature 302, 33-37.
20. Yamashita, N., Murata, M., Inoue, S., Hiraku, Y., Yoshinaga, T. and Kawanishi, S. (1998) "Superoxide formation and DNA damage induced by a fragrant furanone in the presence of copper(II)", Mutat. Res. 397, 191-201.
21. Oikawa, S., Murakami, K. and Kawanishi, S. (2003) "Oxidative damage to cellular and isolated DNA by homocysteine: implications for carcinogenesis", Oncogene 22, 3530-3538.
22. Yamamoto, K. and Kawanishi, S. (1989) "Hydroxyl free radical is not the main active species in site specific DNA damage induced by copper(II) ion and hydrogen peroxide", J. Biol. Chem. 264, 15435-15440.
23. Maxam, A.M. and Gilbert, W. (1980) "Sequencing end-labeled DNA with base-specific chemical cleavages", Meth. Enzymol. 65, 499-560.
24. Kasai, H., Grain, P.F., Kuchino, Y., Nishimura, S., Ootsuyama, A. and Tanooka, H. (1986) "Formation of 8-hydroxyguanine moiety in cellular DNA by agents producing oxygen radicals and evidence for its repair", Carcinogenesis 7, 1849-1851.
25. Ito, K., Inoue, S., Yamamoto, K. and Kawanishi, S. (1993) "8-Hydroxydeoxyguanosine formation at the 5′ site of 5′ -GG-3′ sequence in double-stranded DNA by UV radiation with riboflavin", J. Biol. Chem. 268, 13221-13227.
26. Blair, D. and Diel, H. (1961) "Bathophenanthrolinedisulphonic acid and bathocuproinedisulphonic acid, water soluble reagents for iron and copper", Talanta 7, 163-174.
27. David-Cordonnier, M.H., Laval, J. and O'Neill, P. (2000) "Clustered DNA damage, influence on damage excision by XRS5 nuclear extracts and Escherichia coli Nth and Fpg proteins", J. Biol. Chem. 275, 11865-11873.
28. D'Ham, C., Romieu, A., Jaquinod, M., Gasparutto, D. and Cadet, J. (1999) "Excision of 5,6-dihydroxy-5,6-dihydrothymine, 5,6-dihydrothymine, and 5-hydroxycytosine from defined sequence oligonucleotides by Escherichia coli endonuclease III and Fpg proteins: kinetic and mechanistic aspects", Biochemistry 38, 3335-3344.
29. Bourdat, A.-G., Douki, T., Frelon, S., Gasparutto, D. and Cadet, J. (2000) "Tandem base lesions are generated by hydroxyl radical within isolated DNA in aerated aqueous solution", J. Am. Chem. Soc. 122, 4549-4556.
30. Box, H.C., Budzinski, E.E., Dawidzik, J.B., Gobey, J.S. and Freund, H.G. (1997) "Free radical-induced tandem base damage in DNA oligomers", Free Radic. Biol. Med. 23, 1021-1030.
31. Frelon, S., Douki, T., Favier, A. and Cadet, J. (2003) "Hydroxyl radical is not the main reactive species involved in the degradation of DNA bases by copper in the presence of hydrogen peroxide", Chem. Res. Toxicol. 16, 191-197.
32. Lee, D.H., O'Connor, T.R. and Pfeifer, G.P. (2002) "Oxidative DNA damage induced by copper and hydrogen peroxide promotes CG ⇒ TT tandem mutations at methylated CpG dinucleotides in nucleotide excision repair-deficient cells", Nucleic Acids Res. 30, 3566-3573.
33. Blaisdell, J.O. and Wallace, S.S. (2001) "Abortive base-excision repair of radiation-induced clustered DNA lesions in Escherichia coli", Proc. Natl Acad. Sci. USA 98, 7426-7430.
34. Youngman, R.J. and Elstner, E.F. (1981) "Oxygen species in paraquat toxicity: the crypto-OH radical", FEBS Lett. 129, 265-268.
35. Kawanishi, S., Hiraku, Y. and Oikawa, S. (2001) "Mechanism of guanine-specific DNA damage by oxidative stress and its role in carcinogenesis and aging", Mutat. Res. 488, 65-76.
36. Hirakawa, K., Oikawa, S., Hirkaku, Y., Hirosawa, I. and Kawanishi, S. (2002) "Catechol and hydroquinone have different redox properties responsible for their differential DNA-damaging ability", Chem. Res. Toxicol. 15, 76-82.
37. Dijkwel, P.A. and Wenink, P.W. (1986) "Structural integrity of the nuclear matrix: differential effects of thiol agents and metal chelators", J. Cell Sci. 84, 53-67.
38. Saucier, M.A., Wang, X., Re, R.N., Brown, J. and Bryan, S.E. (1991) "Effects of ionic strength on endogenous nuclease activity in chelated and nonchelated chromatin", J. Inorg. Biochem. 41, 117-124.
39. Theophanides, T. and Anastassopoulou, J. (2002) "Copper and carcinogenesis", Crit. Rev. Oncol. Hematol. 42, 57-64.
40. Bar-Or, D., Thomas, G.W., Rael, L.T., Lau, E.P. and Winkler, J.V. (2001) "Asp-Ala-His-Lys (DAHK) inhibits copper-induced oxidative DNA double strand breaks and telomere shortening", Biochem. Biophys. Res. Commun. 282, 356-360.
41. Linder, M.C. (2001) "Copper and genomic stability in mammals", Mutat. Res. 475, 141-152.
42. 2 photocatalyst", J. Photochem. Photobiol. A Chem. 134, 139-142.
43. Akhlynina, T.V., Jans, D.A., Rosenkranz, A.A., Statsyuk, N.V., Balashova, I.Y., Toth, G., Pavo, I., Rubin, A.B. and Sobolev, A.S. (1997) "Nuclear targeting of chlorin e6 enhances its photosensitizing activity", J. Biol. Chem. 272, 20328-20331.
44. Bisland, S.K., Singh, D. and Gariepy, J. (1999) "Potentiation of chlorin e6 photodynamic activity in vitro with peptide-based intracellular vehicles", Bioconjug. Chem. 10, 982-992.