Use of alkaline Comet assay to assess DNA repair after m-THPC-PDT

Journal of Photochemistry and Photobiology B: Biology

Volumn 56, Issue 2-3, 2000, Pages 118-131

  Rousset, Nathalie ^a   Kerninon, Erwann ^a   Eléouet, Sabine ^a   Le Néel, Tanguy ^b   Auget, Jean Louis ^b   Vonarx, Véronique ^a   Carré, Jérome ^a   Lajat, Youenn ^a   Patrice, Thierry ^a  

^a CHU de Nantes   (France)

^b UNIVERSITÉ DE NANTES   (France)

Author keywords

Comet assay; DNA damage; DNA repair; Meta (Tetrahydroxyphenyl) chlorin (m THPC); Nucleus distribution; Photodynamic therapy

Indexed keywords

3 (4,5 DIMETHYL 2 THIAZOLYL) 2,5 DIPHENYLTETRAZOLIUM BROMIDE; AGAROSE; ALCOHOL; AMINOLEVULINIC ACID; DIMETHYL SULFOXIDE; DNA; EDETIC ACID; MACROGOL 400; PHOTOFRIN; PHOTOSENSITIZING AGENT; SILICON DIOXIDE; SODIUM CHLORIDE; TEMOPORFIN; TETRAKIS(3 HYDROXYPHENYL)CHLORIN; TRYPSIN;

ANIMAL CELL; ANTINEOPLASTIC ACTIVITY; ARTICLE; CELL MEMBRANE; CELL NUCLEUS MEMBRANE; COLORIMETRY; COMET ASSAY; CONTROLLED STUDY; CYTOPLASM; CYTOTOXICITY; DNA DAMAGE; DNA REPAIR; DRUG ACTIVITY; DRUG APPROVAL; DRUG DISTRIBUTION; DRUG SAFETY; FRANCE; GENOTOXICITY; GLIOBLASTOMA; INCUBATION TIME; IRRADIATION; JAPAN; LD 50; MICROFLUOROMETRY; MOUSE; MUTAGENICITY; NONHUMAN; PHARMACOKINETICS; PHOTODYNAMIC THERAPY; PHOTODYNAMICS; PHOTOREACTIVITY; PHOTOTOXICITY; PRIORITY JOURNAL; UNITED STATES;

ANIMAL; CELL DEATH; CELL SURVIVAL; COMET ASSAY; DNA DAMAGE; DNA REPAIR; GLIOMA; MESOPORPHYRINS; MICE; PHOTOCHEMOTHERAPY; PHOTOSENSITIZING AGENTS; TUMOR CELLS, CULTURED;

EID: 0033770052     PISSN: 10111344     EISSN: None     Source Type: Journal    
DOI: 10.1016/S1011-1344(00)00053-1     Document Type: Article

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