Influence of incubation time and sensitizer localization on meta-tetra(hydroxyphenyl)chlorin (mTHPC)-lnduced photoinactivation of cells

Radiation Research

Volumn 168, Issue 2, 2007, Pages 209-217

  Sasnouski, Siarhei ^a,b   Pic, Emilie ^a   Dumas, Dominique ^c,d   Zorin, Vladimir ^b   D'Hallewin, Marie Ange ^a   Guillemin, François ^a   Bezdetnaya, Lina ^a  

^a CENTRE DE RECHERCHE EN AUTOMATIQUE DE NANCY   (France)

^b BELARUSIAN STATE UNIVERSITY   (Belarus)

^c NANCY UNIVERSITÉ   (France)

^d UNIVERSITÉ DE LORRAINE   (France)

Author keywords

[No Author keywords available]

Indexed keywords

TETRAKIS(3 HYDROXYPHENYL)CHLORIN; MESOPORPHYRIN; PHOTOSENSITIZING AGENT; TEMOPORFIN;

ARTICLE; BLEACHING; CLONOGENIC ASSAY; CONTROLLED STUDY; FLUORESCENCE ANALYSIS; FLUORESCENCE MICROSCOPY; HUMAN; HUMAN CELL; INCUBATION TIME; MATHEMATICAL MODEL; PHOTODYNAMIC THERAPY; PRIORITY JOURNAL; PROTEIN FUNCTION; PROTEIN LOCALIZATION; ABSORPTION; PHOTOCHEMOTHERAPY; TIME; TUMOR CELL LINE;

TETRA;

ABSORPTION; CELL LINE, TUMOR; HUMANS; MESOPORPHYRINS; PHOTOCHEMOTHERAPY; PHOTOSENSITIZING AGENTS; TIME FACTORS;

EID: 34548383838     PISSN: 00337587     EISSN: None     Source Type: Journal    
DOI: 10.1667/0033-7587(2007)168[209:IOITAS]2.0.CO;2     Document Type: Article

References (48)

1. T. J. Dougherty, C. J. Gomer, B. W. Henderson, G. Jori, D. Kessel, M. Korbelik, J. Moan and Q. Peng, Photodynamic therapy. J. Natl. Cancer Inst. 90, 889-905 (1998).
2. Q. Peng and J. M. Nesland, Effects of photodynamic therapy on tumor stroma. Ultrastruct. Pathol. 28, 333-340 (2004).
3. R. Bonnett, R. D. White, U. J. Winfield and M. C. Berenbaum, Hydroporphyrins of the meso-tetra(hydroxyphenyl)porphyrin series as tumour photosensitizers. Biochem. J. 261, 277-280 (1989).
4. V. O. Melnikova, L. N. Bezdetnaya, A. Y. Potapenko and F. Guillemin, Photodynamic properties of meta-tetra(hydroxyphenyl)chlorin in human tumor cells. Radiat. Res. 152, 428-435 (1999).
5. S. Coutier, L. N. Bezdetnaya, T. H. Foster, R. M. Parache and F. Guillemin, Effect of irradiation fluence rate on the efficacy of photodynamic therapy and tumor oxygenation in meta-tetra (hydroxyphenyl) chlorin (mTHPC)-sensitized HT29 xenografts in nude mice. Radiat. Res. 158, 339-345 (2002).
6. S. Coutier, S. Mitra, L. N. Bezdetnaya, R. M. Parache, I. Georgakoudi, T. H. Foster and F. Guillemin, Effects of fluence rate on cell survival and photobleaching in meta-tetra-(hydroxyphenyl)chlorinphotosensitized Colo 26 multicell tumor spheroids. Photochem. Photobiol. 73, 297-303 (2001).
7. T. H. Foster, B. D. Pearson, S. Mitra and C. E. Bigelow, Fluorescence anisotropy imaging reveals localization of meso-tetrahydroxyphenyl chlorin in the nuclear envelope. Photochem. Photobiol. 81, 1544-1547 (2005).
8. M. H. Teiten, S. Marchal, M. A. D'Hallewin, F. Guillemin and L. Bezdetnaya, Primary photodamage sites and mitochondrial events after Foscan photosensitization of MCF-7 human breast cancer cells. Photochem. Photobiol. 78, 9-14 (2003).
9. L. B. Lovat, N. F. Jamieson, M. R. Novelli, C. A. Mosse, C. Selvasekar, G. D. Mackenzie, S. M. Thorpe and S. G. Bown, Photodynamic therapy with m-tetrahydroxyphenyl chlorin for high-grade dysplasia and early cancer in Barrett's columnar lined esophagus. Gastrointest. Endosc. 62, 617-623 (2005).
10. C. Hopper, A. Kubler, H. Lewis, I. B. Tran and G. Putman, mTHPC-mediated photodynamic therapy for early oral squamous cell carcinoma. Int. J. Cancer 111, 138-146 (2004).
11. R. W. Redmond, E. J. Land and T. G. Truscott, Aggregation effects on the photophysical properties of porphyrins in relation to mechanisms involved in photodynamic therapy. Adv. Exp. Med. Biol. 193, 293-302 (1985).
12. C. Tanielian, C. Schweitzer, R. Mechin and C. Wolff, Quantum yield of singlet oxygen production by monomeric and aggregated forms of hematoporphyrin derivative. Free Radic. Biol. Med. 30, 208-212 (2001).
13. M. Ambroz, A. J. MacRobert, J. Morgan, G. Rumbles, M. S. Foley and D. Phillips, Time-resolved fluorescence spectroscopy and intracellular imaging of disulphonated aluminium phthalocyanine. J. Photochem. Photobiol. B 22, 105-117 (1994).
14. D. J. Ball, S. R. Wood, D. I. Vernon, J. Griffiths, T. M. Dubbelman and S. B. Brown, The characterisation of three substituted zinc phthalocyanines of differing charge for use in photodynamic therapy. A comparative study of their aggregation and photosensitising ability in relation to mTHPC and polyhaematoporphyrin. J. Photochem. Photobiol. B 45, 28-35 (1998).
15. T. Theodossiou, M. D. Spiro, J. Jacobson, J. S. Hothersall and A. J. Macrobert, Evidence for intracellular aggregation of hypericin and the impact on its photocytotoxicity in PAM 212 murine keratinocytes. Photochem. Photobiol. 80, 438-443 (2004).
16. F. Ricchelli, Photophysical properties of porphyrins in biological membranes. J. Photochem. Photobiol. B 29, 109-118 (1995).
17. V. V. Borovkov, M. Anikin, K. Wasa and Y. Y. Sakata, Structurally controlled porphyrin-aggregation process in phospholipid membranes. Photochem. Photobiol. 63, 477-482 (1996).
18. M. F. Grahn, A. McGuinness, R. Benzie, R. Boyle, M. L. de Jode, M. G. Dilkes, B. Abbas and N. S. Williams, Intracellular uptake, absorption spectrum and stability of the bacteriochlorin photosensitizer 5,10,15,20-tetrakis (m-hydroxyphenyl)bacteriochlorin (mTHPBC). Comparison with 5,10,15,20- tetrakis(m-hydroxyphenyl)chlorin (mTHPC). J. Photochem. Photobiol. B 37, 261-266 (1997).
19. S. Marchal, A. François, D. Dumas, F. Guillemin and L. Bezdetnaya, Relationship between subcellular localisation of Foscan® and caspase activation in photosensitised MCF-7 cells. Br. J. Cancer 96, 944-951 (2007).
20. R. Bonnett, B. D. Djelal and N. Angelina, Physical and chemical studies related to the development of m-THPC (FOSCAN®) for the photodynamic therapy (PDT) of tumours. J. Porphyrins Phthalocyanines 5, 652-661 (2001).
21. M. N. Merzlyak and K. R. Naqvi, On recording the true absorption spectrum and the scattering spectrum of a turbid sample: application to cell suspensions of the cyanobacterium Anabaena variabilis. J. Photochem. Photobiol. B 58, 123-129 (2000).
22. T. Theodossiou and A. J. MacRobert, Comparison of the photodynamic effect of exogenous photoprotoporphyrin and protoporphyrin IX on PAM 212 murine keratinocytes. Photochem. Photobiol. 76, 530-537 (2002).
23. J. S. Dysart and M. S. Patterson, Characterization of Photofrin photobleaching for singlet oxygen dose estimation during photodynamic therapy of MLL cells in vitro. Phys. Med. Biol. 50, 2597-2616 (2005).
24. J. R. Lakowicz, Principles of Fluorescence Spectroscopy. Kluwer, New York, 1999.
25. J. F. Fowler, Differences in survival curve shapes for formal multi-target and multi-hit models. Phys. Med. Biol. 9, 177-188 (1964).
26. S. B. Brown, M. Shillcock and P. Jones, Equilibrium and kinetic studies of the aggregation of porphyrins in aqueous solution. Biochem. J. 153, 279-285 (1976).
27. L. Ma, J. Moan and K. Berg, Evaluation of a new photosensitizer, meso-tetra-hydroxyphenyl-chlorin, for use in photodynamic therapy: A comparison of its photobiological properties with those of two other photosensitizers. Int. J. Cancer 57, 883-888 (1994).
28. J. P. Connelly, S. W. Botchway, D. P. L. Kunz, A. W. Parker and A. J. MacRobert, Time-resolved fluorescence imaging of photosensitiser distributions in mammalian cells using a picosecond laser line-scanning microscope. J. Photochem. Photobiol. A 142, 169-175 (2001).
29. M. Kress, T. Meier, R. Steiner, F. Dolp, R. Erdmann, U. Ortmann and A. Ruck, Time-resolved microspectrofluorometry and fluorescence lifetime imaging of photosensitizers using picosecond pulsed diode lasers in laser scanning microscopes. J. Biomed. Opt. 8, 26-32 (2003).
30. A. D. Scully, R. B. Ostler, A. J. MacRobert, A. W. Parker, C. de Lara, P. O'Neill and D. Phillips, Laser line-scanning confocal fluorescence imaging of the photodynamic action of aluminum and zinc phthalocyanines in V79-4 Chinese hamster fibroblasts. Photochem. Photobiol. 68, 199-204 (1998).
31. A. D. Scully, R. B. Ostler, D. Phillips, P. O'Neill, A. W. Parker and A. J. MacRobert, Application of fluorescence lifetime imaging microscopy to the investigation of intracellular PDT mechanisms. Bioimaging 5, 9-18 (1997).
32. L. Howe, A. Sucheta, O. Einarsdottir and J. Z. Zhang, Time-resolved studies of the excited-state dynamics of meso-tetra(hydroxylphenyl)chlorin in solution. Photochem. Photobiol. 69, 617-623 (1999).
33. R. Bonnett, B. D. Djelal, P. A. Hamilton, G. Martinez and F. Wierrani, Photobleaching of 5,10,15,20-tetrakis(m-hydroxyphenyl)porphyrin (m-THPP) and the corresponding chlorin (m-THPC) and bacteriochlorin (m-THPBC). A comparative study. J. Photochem. Photobiol. B 53, 136-143 (1999).
34. C. Hadjur, N. Lange, J. Rebstein, P. Monnier, H. van den Bergh and G. Wagnières, Spectroscopic studies of photobleaching and photo-product formation of meta(tetrahydroxyphenyl) chlorin (m-THPC) used in photodynamic therapy. The production of singlet oxygen by m-THPC. J. Photochem. Photobiol. B 45, 170-178 (1998).
35. I. Belitchenko, V. Melnikova, L. Bezdetnaya, H. Rezzoug, J. L. Merlin, A. Potapenko and F. Guillemin, Characterization of photodegradation of meta-tetra(hydroxyphenyl)chlorin (mTHPC) in solution: Biological consequences in human tumor cells. Photochem. Photobiol. 67, 584-590 (1998).
36. M. H. Teiten, L. Bezdetnaya, P. Morliere, R. Santus and F. Guillemin, Endoplasmic reticulum and Golgi apparatus are the preferential sites of Foscan localisation in cultured tumour cells. Br. J. Cancer 88, 146-152 (2003).
37. A. Ruck, G. Beck, R. Bachor, N. Akgun, M. H. Gschwend and R. Steiner, Dynamic fluorescence changes during photodynamic therapy in vivo and in vitro of hydrophilic A1(III) phthalocyanine tetrasulphonate and lipophilic Zn(II) phthalocyanine administered in liposomes. J. Photochem. Photobiol. B 36, 127-133 (1996).
38. B. M. Aveline, R. M. Sattler and R. W. Redmond, Environmental effects on cellular photosensitization: Correlation of phototoxicity mechanism with transient absorption spectroscopy measurements. Photochem. Photobiol. 68, 51-62 (1998).
39. L. Lindqvist, A flash photolysis study of fluorescein. Arkiv Kemi. 16, 79-138 (1960).
40. Y. Usui, K. Itoh and M. Koizumi, Switch-over of the mechanism of the primary rocesses in the photo-oxidation of xanthene dyes as revealed by the oxygen consumption experiments. Bull. Chem. Soc. Jpn. 38, 1015-1022 (1965).
41. L. Song, E. J. Hennink, I. T. Young and H. J. Tanke, Photobleaching kinetics of fluorescein in quantitative fluorescence microscopy. Biophys. J. 68, 2588-2600 (1995).
42. R. Rotomskis, S. Bagdonas and G. Streckyte, Spectroscopic studies of photobleaching and photoproduct formation of porphyrins used in tumour therapy. J. Photochem. Photobiol. B 33, 61-67 (1996).
43. T. G. Gantchev, I. J. Urumov and J. E. Van Lier, On the relationship between rate of uptake of Photofrin and cellular responses to photodynamic treatment in vitro. Cancer Biochem. Biophys. 14, 23-34 (1994).
44. E. Maugain, S. Sasnouski, V. Zorin, J. L. Merlin, F. Guillemin and L. Bezdetnaya, Foscan-based photodynamic treatment in vivo: Cor-relation between efficacy and Foscan accumulation in tumor, plasma and leukocytes. Oncol. Rep. 12, 639-645 (2004).
45. M. Triesscheijn, M. Ruevekamp, N. Antonini, H. Neering, F. A. Stewart and P. Baas, Optimizing meso-tetra-hydroxyphenyl-chlorin-mediated photodynamic therapy for basal cell carcinoma. Photochem. Photobiol. 82, 1686-1690 (2006).
46. M. Triesscheijn, M. Ruevekamp, R. Out, T. J. C. Van Berkel, J. Schellens, P. Baas and F. A. Stewart, The pharmacokinetic behavior of the photosensitizer meso-tetra-hydroxyphenyl-chlorin in mice and men. Cancer Chemother. Pharmacol. 60, 113-122 (2007).
47. S. Andrejevic Blant, P. Grosjean, J-P. Ballini, G. Wagnières, H. van den Bergh, Ch. Fontolliet and Ph. Monnier, Localization of tetra(m-hydroxyphenyl)chlorin (Foscan) in human healthy tissues and squamous cell carcinomas of the upper aero-digestive tract, the esophagus and the bronchi: A fluorescence microscopy study. J. Photochem. Photobiol. B 61, 1-9 (2001).
48. B. W. Henderson, T. M. Busch, L. A. Vaughan, N. P. Frawley, D. Babich, T. A. Sosa, J. D. Zollo, A. S. Dee, M. T. Cooper and A. R. Oseroff, Photofrin photodynamic therapy can significantly deplete or preserve oxygenation in human basal cell carcinomas during treatment, depending on fluence rate. Cancer Res. 60, 525-529 (2000).