Functional reduction of SK3-mediated currents precedes AMPA-receptor- mediated excitotoxicity in dopaminergic neurons

Neuropharmacology

Volumn 60, Issue 7-8, 2011, Pages 1176-1186

  Benítez, Bruno A ^a   Belálcazar, Helen M ^a   Anastasía, Agustín ^b   Mamah, Daniel T ^b   Zorumski, Charles F ^b   Mascó, Daniel H ^b   Herrera, Daniel G ^a   De Erausquin, Gabriel A ^a,c  

^a BRIGHAM AND WOMEN S HOSPITAL   (United States)

^b WASHINGTON UNIVERSITY   (United States)

^c HARVARD INSTITUTES OF MEDICINE   (United States)

Author keywords

1 Ebio; Apamin; CyPPA; Dopaminergic; Excitotoxicity; Neuroprotection; NS8593 AMPA; SK channels

Indexed keywords

AMPA RECEPTOR; APAMIN; CALCIUM; SMALL CONDUCTANCE CALCIUM ACTIVATED POTASSIUM CHANNEL; 1 ETHYL 2 BENZIMIDAZOLINONE; N (BENZIMIDAZOL 2 YL) 1,2,3,4 TETRAHYDRO 1 NAPHTYLAMINE; N CYCLOHEXYL N 2 (3,5 DIMETHYL PYRAZOL 1 YL) 6 METHYL 4 PYRIMIDINAMINE; NAPHTHALENE DERIVATIVE; POTASSIUM CHANNEL STIMULATING AGENT; SMALL CONDUCTANCE CALCIUM ACTIVATED POTASSIUM CHANNEL 3; UNCLASSIFIED DRUG;

ANIMAL CELL; ARTICLE; CALCIUM MOBILIZATION; CELL SURVIVAL; CHANNEL GATING; CONTROLLED STUDY; DOPAMINERGIC NERVE CELL; EMBRYO; EXCITOTOXICITY; NEGATIVE FEEDBACK; NERVE CELL DIFFERENTIATION; NEUROPROTECTION; NONHUMAN; POTASSIUM CONDUCTANCE; PRIORITY JOURNAL; RAT; ANIMAL TISSUE; CELL DIFFERENTIATION; CELL PROTECTION; CONCENTRATION RESPONSE; ENZYME ACTIVITY; ENZYME INHIBITION; IN VITRO STUDY; NERVE CELL STIMULATION; PROTEIN EXPRESSION; PROTEIN FUNCTION; TREATMENT RESPONSE;

1-NAPHTHYLAMINE; ACTION POTENTIALS; ALPHA-AMINO-3-HYDROXY-5-METHYL-4-ISOXAZOLEPROPIONIC ACID; ANIMALS; APAMIN; BENZIMIDAZOLES; CALCIUM CHANNEL AGONISTS; CELL CULTURE TECHNIQUES; DOPAMINE; EXCITATORY AMINO ACID AGONISTS; INTERMEDIATE-CONDUCTANCE CALCIUM-ACTIVATED POTASSIUM CHANNELS; MESENCEPHALON; NEURONS; NEUROTOXINS; PATCH-CLAMP TECHNIQUES; PYRAZOLES; PYRIMIDINES; RATS; RATS, SPRAGUE-DAWLEY; RECEPTORS, AMPA; RECEPTORS, DOPAMINE; SMALL-CONDUCTANCE CALCIUM-ACTIVATED POTASSIUM CHANNELS;

EID: 79954608902     PISSN: 00283908     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.neuropharm.2010.10.024     Document Type: Article

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