Amphetamine selectively blocks inhibitory glutamate transmission in dopamine neurons

Nature Neuroscience

Volumn 4, Issue 3, 2001, Pages 275-281

  Paladini, Carlos A ^a   Fiorillo, Christopher D ^a,b   Morikawa, Hitoshi ^a   Williams, John T ^a  

^a OREGON HEALTH AND SCIENCE UNIVERSITY   (United States)

^b UNIVERSITY OF FRIBOURG   (Switzerland)

Author keywords

[No Author keywords available]

Indexed keywords

4 AMINOBUTYRIC ACID A RECEPTOR; 4 AMINOBUTYRIC ACID B RECEPTOR; ALPHA 1 ADRENERGIC RECEPTOR; AMPA RECEPTOR; AMPHETAMINE; CALCIUM ION; DOPAMINE; DOPAMINE 2 RECEPTOR; DOPAMINE AUTORECEPTOR; GLUTAMIC ACID; INOSITOL TRISPHOSPHATE; METABOTROPIC RECEPTOR; N METHYL DEXTRO ASPARTIC ACID RECEPTOR; NORADRENALIN;

ANIMAL TISSUE; ARTICLE; CALCIUM TRANSPORT; CONTROLLED STUDY; DOPAMINE RELEASE; DOPAMINERGIC NERVE CELL; DOPAMINERGIC TRANSMISSION; HYPERPOLARIZATION; INHIBITORY POSTSYNAPTIC POTENTIAL; MALE; MESENCEPHALON; NONHUMAN; PRIORITY JOURNAL; RAT; RECEPTOR DOWN REGULATION; REWARD; SUBSTANTIA NIGRA; VENTRAL TEGMENTUM; VOLTAGE CLAMP;

AMPHETAMINE; ANIMALS; CALCIUM; CALCIUM SIGNALING; CARRIER PROTEINS; DOPAMINE; DOPAMINE PLASMA MEMBRANE TRANSPORT PROTEINS; GLUTAMIC ACID; MALE; MEMBRANE GLYCOPROTEINS; MEMBRANE TRANSPORT PROTEINS; NERVE TISSUE PROTEINS; NEURAL INHIBITION; NEURONS; POTASSIUM CHANNELS; RATS; RATS, WISTAR; RECEPTORS, ADRENERGIC, ALPHA-1; RECEPTORS, AMPA; RECEPTORS, METABOTROPIC GLUTAMATE; SYNAPTIC TRANSMISSION; VENTRAL TEGMENTAL AREA;

EID: 0035119780     PISSN: 10976256     EISSN: None     Source Type: Journal    
DOI: 10.1038/85124     Document Type: Article

References (44)

1. Vesicular transport regulates monoamine storage and release but is not essential for amphetamine action
2. Repeated cocaine modifies the mechanism by which amphetamine releases dopamine
3. Mechanisms of amphetamine action revealed in mice lacking the dopamine transporter
4. Neurotransmitter transporters as molecular targets for addictive drugs
5. Self-inhibition by dopaminergic neurons
6. The mechanism of amphetamine-induced inhibition of rat substantia nigra compacta neurones investigated with intracellular recording in vitro
7. Locally application of amphetamine into the ventral tegmental area enhances dopamine release in the nucleus accumbens and the medial prefrontal cortex through noradrenergic neurotransmission
8. Importance of the noradrenaline-dopamine coupling in the locomotor activating effects of D-amphetamine
9. Dual effects of D-amphetamine on dopamine neurons mediated by dopamine and nondopamine receptors
10. Amphetamine blocks long-term synaptic depression in the ventral tegmental area
11. Phasic versus tonic dopamine release and the modulation of dopamine system responsivity: A hypothesis for the etiology of schizophrenia
12. Predictive reward signal of dopamine neurons
13. Burst firing in midbrain dopaminergic neurons
14. Nonlinear relationship between impulse flow and dopamine released by rat midbrain dopaminergic neurons as studied by in vivo electrochemistry
15. Relationship between dopamine release in the rat nucleus accumbens and the discharge activity of dopaminergic neurons during local in vivo application of amino acids in the ventral tegmental area
16. Glutamate mediates an inhibitory postsynaptic potential in dopamine neurons
17. Amphetamine levels in brain microdialysate, caudate/putamen, substantial nigra and plasma after dosage that produces either behavioral or neurotoxic effects
18. Drug level of D- And L-amphetamine during intravenous self-administration
19. Selective inhibition by adenosine of mGluR IPSPs in dopamine neurons following cocaine treatment
20. Amphetamine depresses excitatory synaptic transmission via serotonin receptors in the ventral tegmental area
21. 1-adrenergic effects on dopamine neurons recorded intracellularly in the rat midbrain slice
22. Interactions of epinephrine, noradrenaline, dopamine, and their corresponding alphamethyl-substituted derivatives with alpha and beta adrenoceptors in the pithed rat
23. 3H]idazoxan
24. Inositol 1,4,5-triphosphate-evoked responses in midbrain dopamine neurons
25. Group 1 metabotropic glutamate receptors mediate an inward current in rat substantia nigra dopamine neurons that is independent from calcium mobilization
26. Electrophysiological evidence for a reciprocal interaction between amphetamine and cocaine-related drugs on rat midbrain dopaminergic neurons
27. Noradrenergic modulation of midbrain dopamine cell firing elicited by stimulation of the locus coeruleus in the rat
28. Psychostimulants depress excitatory synaptic transmission in the nucleus accumbens via presynaptic D1 -like dopamine receptors
29. Endogenous and exogenous dopamine depress EPSCs in rat nucleus accumbens in vitro via D1 receptor activation
30. Endogenous monoamines inhibit glutamate transmission in the spinal trigeminal nucleus of the guinea-pig
31. Cholinergic inhibition of ventral midbrain dopamine neurons
32. The inositol trisphosphate calcium channel is inactivated by inositol trisphosphate
33. The control of firing pattern in nigral dopamine neurons: Burst firing
34. Enhanced vulnerability to cocaine self-administration is associated with elevated impulse activity of midbrain dopamine neurons
35. Modulation of long-term depression by dopamine in the mesolimbic system
36. Blockade of prefronto-cortical alpha 1-adrenergic receptors prevents locomotor hyperactivity induced by subcortical D-amphetamine injection
37. Alpha 1- And alpha 2-adrenoreceptor antagonists differentially influence locomotor and stereotyped behaviour induced by d-amphetamine and apomorphine in the rat
38. Differential modulation of (+)-amphetamine-induced rotation in unilateral substantia nigra lesioned rats by alpha 1 as compared to alpha 2 agonists and antagonists
39. The progressive ratio schedule as a model for studying the psychomotor stimulant activity of drugs in the rat
40. Prazosin: Effect on psychomotor-stimulant cues and locomotor activity in mice
41. Antagonism of the behavioral effects of cocaine and d-amphetamine by prazosin
42. Prazosin modulates the firing pattern of dopamine neurons in rat ventral tegmental area
43. Membrane properties of rat locus coeruleus neurones
44. Two types of neurone in the rat ventral tegmental area and their synaptic inputs