메뉴 건너뛰기




Volumn 117, Issue 15, 2011, Pages 4056-4064

JAK2 rearrangements, including the novel SEC31A-JAK2 fusion, are recurrent in classical Hodgkin lymphoma

Author keywords

[No Author keywords available]

Indexed keywords

4 [N [1 (2 CYANO 1 OXOETHYL) 4 METHYL 3 PIPERIDINYL] N METHYLAMINO]PYRROLO[2,3 D]PYRIMIDINE; BLEOMYCIN; DACARBAZINE; DOXORUBICIN; JANUS KINASE 2; PROTEIN TYROSINE KINASE; STAT PROTEIN; VINBLASTINE;

EID: 79954606783     PISSN: 00064971     EISSN: 15280020     Source Type: Journal    
DOI: 10.1182/blood-2010-06-291310     Document Type: Article
Times cited : (93)

References (52)
  • 6
    • 50249116142 scopus 로고    scopus 로고
    • Novel SSBP2-JAK2 fusion gene resulting from at (5;9) (q14.1;p24.1) in pre-B acute lymphocytic leukemia
    • Poitras JL, Dal Cin P, Aster JC, Deangelo DJ, Morton CC. Novel SSBP2-JAK2 fusion gene resulting from at (5;9) (q14.1;p24.1) in pre-B acute lymphocytic leukemia. Genes Chromosomes Cancer. 2008;47(10):884-889.
    • (2008) Genes Chromosomes Cancer , vol.47 , Issue.10 , pp. 884-889
    • Poitras, J.L.1    Cin, P.D.2    Aster, J.C.3    Deangelo, D.J.4    Morton, C.C.5
  • 7
    • 78649731391 scopus 로고    scopus 로고
    • Next generation transcriptomic resequencing identifies novel genetic alterations in high-risk (HR) childhood acute lymphoblastic leukemia (ALL): A report from the children's oncology group (COG) HR ALLTARGET project [abstract]
    • Abstract 704
    • Mullighan CG, Morin R, Zhang J, et al. Next generation transcriptomic resequencing identifies novel genetic alterations in high-risk (HR) childhood acute lymphoblastic leukemia (ALL): a report from the Children's Oncology Group (COG) HR ALLTARGET Project [abstract]. Blood (ASH Annual Meeting Abstracts). 2009;114(22):293-294. Abstract 704.
    • (2009) Blood (ASH Annual Meeting Abstracts) , vol.114 , Issue.22 , pp. 293-294
    • Mullighan, C.G.1    Morin, R.2    Zhang, J.3
  • 8
    • 58249118804 scopus 로고    scopus 로고
    • Incidence and diversity of PAX5 fusion genes in childhood acute lymphoblastic leukemia
    • Nebral K, Denk D, Attarbaschi A, et al. Incidence and diversity of PAX5 fusion genes in childhood acute lymphoblastic leukemia. Leukemia. 2009;23(1):134-143.
    • (2009) Leukemia , vol.23 , Issue.1 , pp. 134-143
    • Nebral, K.1    Denk, D.2    Attarbaschi, A.3
  • 9
    • 34147176683 scopus 로고    scopus 로고
    • A novel PAX5-ELN fusion protein identified in B-cell acute lymphoblastic leukemia acts as a dominant negative on wild-type PAX5
    • DOI 10.1182/blood-2006-05-025221
    • Bousquet M, Broccardo C, Quelen C, et al. A novel PAX5-ELN fusion protein identified in B-cell acute lymphoblastic leukemia acts as a dominant negative on wild-type PAX5. Blood. 2007;109(8):3417-3423. (Pubitemid 46572531)
    • (2007) Blood , vol.109 , Issue.8 , pp. 3417-3423
    • Bousquet, M.1    Broccardo, C.2    Quelen, C.3    Meggetto, F.4    Kuhlein, E.5    Delsol, G.6    Dastugue, N.7    Brousset, P.8
  • 10
    • 39149096620 scopus 로고    scopus 로고
    • PAX5/TEL acts as a transcriptional repressor causing down-modulation of CD19, enhances migration to CXCL12, and confers survival advantage in pre-BI cells
    • DOI 10.1158/0008-5472.CAN-07-2778
    • Fazio G, Palmi C, Rolink A, Biondi A, Cazzaniga G. PAX5/TEL acts as a transcriptional repressor causing down-modulation of CD19, enhances migration to CXCL12, and confers survival advantage in pre-BI cells. Cancer Res. 2008;68(1):181-189. (Pubitemid 351380119)
    • (2008) Cancer Research , vol.68 , Issue.1 , pp. 181-189
    • Fazio, G.1    Palmi, C.2    Rolink, A.3    Biondi, A.4    Cazzaniga, G.5
  • 11
    • 77950915903 scopus 로고    scopus 로고
    • The current status and the future of JAK2 inhibitors for the treatment of myeloproliferative diseases
    • Hitoshi Y, Lin N, Payan DG, Markovtsov V. The current status and the future of JAK2 inhibitors for the treatment of myeloproliferative diseases. Int J Hematol. 2010;91(2):189-200.
    • (2010) Int. J. Hematol , vol.91 , Issue.2 , pp. 189-200
    • Hitoshi, Y.1    Lin, N.2    Payan, D.G.3    Markovtsov, V.4
  • 12
    • 0028007479 scopus 로고
    • Hodgkin disease: Hodgkin and Reed-Sternberg cells picked from histological sections show clonal immunoglobulin gene rearrangements and appear to be derived from B cells at various stages of development
    • Kuppers R, Rajewsky K, Zhao M, et al. Hodgkin disease: Hodgkin and Reed-Sternberg cells picked from histological sections show clonal immunoglobulin gene rearrangements and appear to be derived from B cells at various stages of development. Proc Natl Acad Sci U S A. 1994;91(23):10962- 10966.
    • (1994) Proc. Natl. Acad. Sci. U S A , vol.91 , Issue.23 , pp. 10962-10966
    • Kuppers, R.1    Rajewsky, K.2    Zhao, M.3
  • 14
    • 57749171165 scopus 로고    scopus 로고
    • The biology of Hodgkin's lymphoma
    • Kuppers R. The biology of Hodgkin's lymphoma. Nat Rev Cancer. 2009;9(1):15-27.
    • (2009) Nat. Rev. Cancer , vol.9 , Issue.1 , pp. 15-27
    • Kuppers, R.1
  • 15
    • 33646382121 scopus 로고    scopus 로고
    • Mutations of the tumor suppressor gene SOCS-1 in classical Hodgkin lymphoma are frequent and associated with nuclear phospho-STAT5 accumulation
    • Weniger MA, Melzner I, Menz CK, et al. Mutations of the tumor suppressor gene SOCS-1 in classical Hodgkin lymphoma are frequent and associated with nuclear phospho-STAT5 accumulation. Oncogene. 2006;25(18):2679-2684.
    • (2006) Oncogene , vol.25 , Issue.18 , pp. 2679-2684
    • Weniger, M.A.1    Melzner, I.2    Menz, C.K.3
  • 16
    • 50849089966 scopus 로고    scopus 로고
    • Detection of genomic imbalances in microdissected Hodgkin and Reed-Sternberg cells of classical Hodgkin's lymphoma by array-based comparative genomic hybridization
    • Hartmann S, Martin-Subero JI, Gesk S, et al. Detection of genomic imbalances in microdissected Hodgkin and Reed-Sternberg cells of classical Hodgkin's lymphoma by array-based comparative genomic hybridization. Haematologica. 2008;93(9):1318-1326.
    • (2008) Haematologica , vol.93 , Issue.9 , pp. 1318-1326
    • Hartmann, S.1    Martin-Subero, J.I.2    Gesk, S.3
  • 18
    • 61349087903 scopus 로고    scopus 로고
    • Recurrent numerical aberrations of JAK2 and deregulation of the JAK2-STAT cascade in lymphomas
    • Meier C, Hoeller S, Bourgau C, et al. Recurrent numerical aberrations of JAK2 and deregulation of the JAK2-STAT cascade in lymphomas. Mod Pathol. 2009;22(3):476-487.
    • (2009) Mod Pathol. , vol.22 , Issue.3 , pp. 476-487
    • Meier, C.1    Hoeller, S.2    Bourgau, C.3
  • 19
    • 33644987681 scopus 로고    scopus 로고
    • Absence of the JAK2 V617F activating mutation in classical Hodgkin lymphoma and primary mediastinal B-cell lymphoma
    • Melzner I, Weniger MA, Menz CK, Moller P. Absence of the JAK2 V617F activating mutation in classical Hodgkin lymphoma and primary mediastinal B-cell lymphoma. Leukemia. 2006;20(1):157-158.
    • (2006) Leukemia , vol.20 , Issue.1 , pp. 157-158
    • Melzner, I.1    Weniger, M.A.2    Menz, C.K.3    Moller, P.4
  • 22
    • 85081504409 scopus 로고    scopus 로고
    • Ensembl Genome Browser: Release 57, March 2010, Accessed April 2010
    • Ensembl Genome Browser: Release 57, March 2010. http://www.ensembl.org. Accessed April 2010.
  • 23
    • 85081512253 scopus 로고    scopus 로고
    • UCSC Genome Browser: NCBI37/mm assembly 7/07 update, Accessed April 2010
    • UCSC Genome Browser: NCBI37/mm assembly 7/07 update. http://genome.ucsc. edu. Accessed April 2010.
  • 24
    • 77949725060 scopus 로고    scopus 로고
    • ALK-positive large B-cell lymphomas with cryptic SEC31A-ALK and NPM1-ALK fusions
    • Van Roosbroeck K, Cools J, Dierickx D, et al. ALK-positive large B-cell lymphomas with cryptic SEC31A-ALK and NPM1-ALK fusions. Haematologica. 2010;95(3):509-513.
    • (2010) Haematologica , vol.95 , Issue.3 , pp. 509-513
    • Van Roosbroeck, K.1    Cools, J.2    Dierickx, D.3
  • 27
    • 0036093475 scopus 로고    scopus 로고
    • FLT3 internal tandem duplication mutations associated with human acute myeloid leukemias induce myeloproliferative disease in a murine bone marrow transplant model
    • Kelly LM, Liu Q, Kutok JL, et al. FLT3 internal tandem duplication mutations associated with human acute myeloid leukemias induce myeloproliferative disease in a murine bone marrow transplant model. Blood. 2002;99(1):310-318.
    • (2002) Blood , vol.99 , Issue.1 , pp. 310-318
    • Kelly, L.M.1    Liu, Q.2    Kutok, J.L.3
  • 34
    • 0010182347 scopus 로고    scopus 로고
    • Mammalian homologues of yeast Sec31p. An ubiquitously expressed form is localized to endoplasmic reticulum (ER) exit sites and is essential for ER- Golgi transport
    • DOI 10.1074/jbc.275.18.13597
    • Tang BL, Zhang T, Low DY, et al. Mammalian homologues of yeast sec31p. An ubiquitously expressed form is localized to endoplasmic reticulum (ER) exit sites and is essential for ER-Golgi transport. J Biol Chem. 2000;275(18):13597- 13604. (Pubitemid 30257427)
    • (2000) Journal of Biological Chemistry , vol.275 , Issue.18 , pp. 13597-13604
    • Tang, B.L.1    Zhang, T.2    Low, D.Y.H.3    Wong, E.T.4    Horstmann, H.5    Hong, W.6
  • 35
    • 33750534358 scopus 로고    scopus 로고
    • 2+-binding protein ALG-2 is recruited to endoplasmic reticulum exit sites by Sec31A and stabilizes the localization of Sec31A
    • DOI 10.1091/mbc.E06-05-0444
    • Yamasaki A, Tani K, Yamamoto A, Kitamura N, Komada M. The Ca2+-binding protein ALG-2 is recruited to endoplasmic reticulum exit sites by Sec31A and stabilizes the localization of Sec31A. Mol Biol Cell. 2006;17(11):4876-4887. (Pubitemid 44665756)
    • (2006) Molecular Biology of the Cell , vol.17 , Issue.11 , pp. 4876-4887
    • Yamasaki, A.1    Tani, K.2    Yamamoto, A.3    Kitamura, N.4    Komada, M.5
  • 36
    • 35549004893 scopus 로고    scopus 로고
    • Insights into COPII Coat Nucleation from the Structure of Sec23•Sar1 Complexed with the Active Fragment of Sec31
    • DOI 10.1016/j.devcel.2007.10.006, PII S153458070700384X
    • Bi X, Mancias JD, Goldberg J. Insights into COPII coat nucleation from the structure of Sec23. Sar1 complexed with the active fragment of Sec31. Dev Cell. 2007;13(5):635-645. (Pubitemid 350011990)
    • (2007) Developmental Cell , vol.13 , Issue.5 , pp. 635-645
    • Bi, X.1    Mancias, J.D.2    Goldberg, J.3
  • 40
    • 33644976909 scopus 로고    scopus 로고
    • Atransgenic mouse model for TEL-JAK2-induced B-cell lymphoma/leukemia
    • dos Santos NR, Ghysdael J. Atransgenic mouse model for TEL-JAK2-induced B-cell lymphoma/leukemia. Leukemia. 2006;20(1):182-185.
    • (2006) Leukemia , vol.20 , Issue.1 , pp. 182-185
    • Dos Santos, N.R.1    Ghysdael, J.2
  • 41
    • 0033230394 scopus 로고    scopus 로고
    • Frequent expression of the B-cell-specific activator protein in Reed- Sternberg cells of classical Hodgkin's disease provides further evidence for its B-cell origin
    • Foss HD, Reusch R, Demel G, et al. Frequent expression of the B-cell specific activator protein in Reed-Sternberg cells of classical Hodgkin's disease provides further evidence for its B-cell origin. Blood. 1999;94(9):3108-3113. (Pubitemid 29512717)
    • (1999) Blood , vol.94 , Issue.9 , pp. 3108-3113
    • Foss, H.-D.1    Reusch, R.2    Demel, G.3    Lenz, G.4    Anagnostopoulos, I.5    Hummel, M.6    Stein, H.7
  • 43
    • 0026518130 scopus 로고
    • Hodgkin's disease, lymphomatoid papulosis, and cutaneous T-cell lymphoma derived from a common T-cell clone
    • Davis TH, Morton CC, Miller-Cassman R, Balk SP, Kadin ME. Hodgkin's disease, lymphomatoid papulosis, and cutaneous T-cell lymphoma derived from a common T-cell clone. N Engl J Med. 1992;326(17):1115-1122.
    • (1992) N. Engl. J. Med. , vol.326 , Issue.17 , pp. 1115-1122
    • Davis, T.H.1    Morton, C.C.2    Miller-Cassman, R.3    Balk, S.P.4    Kadin, M.E.5
  • 44
    • 0035180858 scopus 로고    scopus 로고
    • Hodgkin's lymphoma of T-cell type: Clonal association with a CD30+ cutaneous lymphoma
    • DOI 10.1053/hupa.2001.28963
    • Kadin ME, Drews R, Samel A, Gilchrist A, Kocher O. Hodgkin's lymphoma of T-cell type: clonal association with a CD30+ cutaneous lymphoma. Hum Pathol. 2001;32(11):1269-1272. (Pubitemid 33104440)
    • (2001) Human Pathology , vol.32 , Issue.11 , pp. 1269-1272
    • Kadin, M.E.1    Drews, R.2    Samel, A.3    Gilchrist, A.4    Kocher, O.5
  • 46
    • 0034658050 scopus 로고    scopus 로고
    • Detection of clonal T-cell receptor gamma-chain gene rearrangements Reed-Sternberg cells of classic Hodgkin disease
    • Seitz V, Hummel M, Marafioti T, et al. Detection of clonal T-cell receptor gamma-chain gene rearrangements in Reed-Sternberg cells of classic Hodgkin disease. Blood. 2000;95(10):3020-3024. (Pubitemid 30321149)
    • (2000) Blood , vol.95 , Issue.10 , pp. 3020-3024
    • Seitz, V.1    Hummel, M.2    Marafioti, T.3    Anagnostopoulos, I.4    Assaf, C.5    Stein, H.6
  • 51
    • 4644275423 scopus 로고    scopus 로고
    • BCL11B rearrangements probably target T-cell neoplasia rather than acute myelocytic leukemia [4]
    • DOI 10.1016/j.cancergencyto.2004.02.020, PII S0165460804001074
    • Macleod RA, Nagel S, Drexler HG. BCL11B rearrangements probably target T-cell neoplasia rather than acute myelocytic leukemia. Cancer Genet Cytogenet. 2004;153(1):88-89. (Pubitemid 39592139)
    • (2004) Cancer Genetics and Cytogenetics , vol.153 , Issue.1 , pp. 88-89
    • MacLeod, R.A.F.1    Nagel, S.2    Drexler, H.G.3


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.