-
1
-
-
33846216449
-
Jak2: Normal function and role in hematopoietic disorders
-
Ihle JN, Gilliland DG. Jak2: normal function and role in hematopoietic disorders. Curr Opin Genet Dev 2007;17:8-14.
-
(2007)
Curr Opin Genet Dev
, vol.17
, pp. 8-14
-
-
Ihle, J.N.1
Gilliland, D.G.2
-
2
-
-
20144363192
-
Acquired mutation of the tyrosine kinase JAK2 in human myeloproliferative disorders
-
Baxter EJ, Scott LM, Campbell PJ, et al. Acquired mutation of the tyrosine kinase JAK2 in human myeloproliferative disorders. Lancet 2005;365:1054-1061.
-
(2005)
Lancet
, vol.365
, pp. 1054-1061
-
-
Baxter, E.J.1
Scott, L.M.2
Campbell, P.J.3
-
3
-
-
17644424955
-
A gain-of-function mutation of JAK2 in myeloproliferative disorders
-
Kralovics R, Passamonti F, Buser AS, et al. A gain-of-function mutation of JAK2 in myeloproliferative disorders. N Engl J Med 2005;352:1779-1790.
-
(2005)
N Engl J Med
, vol.352
, pp. 1779-1790
-
-
Kralovics, R.1
Passamonti, F.2
Buser, A.S.3
-
4
-
-
20244369569
-
Activating mutation in the tyrosine kinase JAK2 in polycythemia vera, essential thrombocythemia, and myeloid metaplasia with myelofibrosis
-
Levine RL, Wadleigh M, Cools J, et al. Activating mutation in the tyrosine kinase JAK2 in polycythemia vera, essential thrombocythemia, and myeloid metaplasia with myelofibrosis. Cancer Cell 2005;7:387-397.
-
(2005)
Cancer Cell
, vol.7
, pp. 387-397
-
-
Levine, R.L.1
Wadleigh, M.2
Cools, J.3
-
5
-
-
33644552449
-
A t(8;9) translocation with PCM1-JAK2 fusion in a patient with T-cell lymphoma
-
Adelaide J, Perot C, Gelsi-Boyer V, et al. A t(8;9) translocation with PCM1-JAK2 fusion in a patient with T-cell lymphoma. Leukemia 2006;20:536-537.
-
(2006)
Leukemia
, vol.20
, pp. 536-537
-
-
Adelaide, J.1
Perot, C.2
Gelsi-Boyer, V.3
-
6
-
-
27944481825
-
The t(8;9)(p22;p24) translocation in atypical chronic myeloid leukaemia yields a new PCM1-JAK2 fusion gene
-
Bousquet M, Quelen C, De M, et al. The t(8;9)(p22;p24) translocation in atypical chronic myeloid leukaemia yields a new PCM1-JAK2 fusion gene. Oncogene 2005;24:7248-7252.
-
(2005)
Oncogene
, vol.24
, pp. 7248-7252
-
-
Bousquet, M.1
Quelen, C.2
De, M.3
-
7
-
-
26644433894
-
Myelodysplastic/ myeloproliferative disease with erythropoietic hyperplasia (erythroid preleukemia) and the unique translocation (8;9)(p23;p24): First description of a case
-
Heiss S, Erdel M, Gunsilius E, et al. Myelodysplastic/ myeloproliferative disease with erythropoietic hyperplasia (erythroid preleukemia) and the unique translocation (8;9)(p23;p24): first description of a case. Hum Pathol 2005;36:1148-1151.
-
(2005)
Hum Pathol
, vol.36
, pp. 1148-1151
-
-
Heiss, S.1
Erdel, M.2
Gunsilius, E.3
-
8
-
-
33750497611
-
Chronic idiopathic myelofibrosis (CIMF) resulting from a unique 3;9 translocation disrupting the Janus kinase 2 (JAK2) gene
-
Mark HF, Sotomayor EA, Nelson M, et al. Chronic idiopathic myelofibrosis (CIMF) resulting from a unique 3;9 translocation disrupting the Janus kinase 2 (JAK2) gene. Exp Mol Pathol 2006;81:217-223.
-
(2006)
Exp Mol Pathol
, vol.81
, pp. 217-223
-
-
Mark, H.F.1
Sotomayor, E.A.2
Nelson, M.3
-
9
-
-
26944481210
-
PCM1-JAK2 fusion in myeloproliferative disorders and acute erythroid leukemia with t(8;9) translocation
-
Murati A, Gelsi-Boyer V, Adelaide J, et al. PCM1-JAK2 fusion in myeloproliferative disorders and acute erythroid leukemia with t(8;9) translocation. Leukemia 2005;19:1692-1696.
-
(2005)
Leukemia
, vol.19
, pp. 1692-1696
-
-
Murati, A.1
Gelsi-Boyer, V.2
Adelaide, J.3
-
10
-
-
20144389913
-
The t(8;9)(p22;p24) is a recurrent abnormality in chronic and acute leukemia that fuses PCM1 to JAK2
-
Reiter A, Walz C, Watmore A, et al. The t(8;9)(p22;p24) is a recurrent abnormality in chronic and acute leukemia that fuses PCM1 to JAK2. Cancer Res 2005;65:2662-2667.
-
(2005)
Cancer Res
, vol.65
, pp. 2662-2667
-
-
Reiter, A.1
Walz, C.2
Watmore, A.3
-
11
-
-
33746043322
-
The role of Janus kinases in haemopoiesis and haematological malignancy
-
Khwaja A. The role of Janus kinases in haemopoiesis and haematological malignancy. Br J Haematol 2006;134:366-384.
-
(2006)
Br J Haematol
, vol.134
, pp. 366-384
-
-
Khwaja, A.1
-
12
-
-
0343820067
-
Genomic imbalances including amplification of the tyrosine kinase gene JAK2 in CD30+ Hodgkin cells
-
Joos S, Kupper M, Ohl S, et al. Genomic imbalances including amplification of the tyrosine kinase gene JAK2 in CD30+ Hodgkin cells. Cancer Res 2000;60:549-552.
-
(2000)
Cancer Res
, vol.60
, pp. 549-552
-
-
Joos, S.1
Kupper, M.2
Ohl, S.3
-
13
-
-
32144453842
-
-
Valentino L, Pierre J. JAK/STAT signal transduction: regulators and implication in hematological malignancies. Biochem Pharmacol 2006;71:713-721.
-
Valentino L, Pierre J. JAK/STAT signal transduction: regulators and implication in hematological malignancies. Biochem Pharmacol 2006;71:713-721.
-
-
-
-
14
-
-
0036731485
-
Stats: Transcriptional control and biological impact
-
Levy DE, Darnell Jr JE. Stats: transcriptional control and biological impact. Nat Rev Mol Cell Biol 2002;3:651-662.
-
(2002)
Nat Rev Mol Cell Biol
, vol.3
, pp. 651-662
-
-
Levy, D.E.1
Darnell Jr, J.E.2
-
15
-
-
33845348577
-
The JAK-STAT pathway: A therapeutic target in hematological malignancies
-
Ferrajoli A, Faderl S, Ravandi F, et al. The JAK-STAT pathway: a therapeutic target in hematological malignancies. Curr Cancer Drug Targets 2006;6:671-679.
-
(2006)
Curr Cancer Drug Targets
, vol.6
, pp. 671-679
-
-
Ferrajoli, A.1
Faderl, S.2
Ravandi, F.3
-
16
-
-
85047699293
-
Anaplastic lymphoma kinase (ALK) activates Stat3 and protects hematopoietic cells from cell death
-
Zamo A, Chiarle R, Piva R, et al. Anaplastic lymphoma kinase (ALK) activates Stat3 and protects hematopoietic cells from cell death. Oncogene 2002;21:1038-1047.
-
(2002)
Oncogene
, vol.21
, pp. 1038-1047
-
-
Zamo, A.1
Chiarle, R.2
Piva, R.3
-
17
-
-
33748341084
-
JSI-124 (cucurbitacin I) inhibits Janus kinase-3/signal transducer and activator of transcription-3 signalling, downregulates nucleophosmin-anaplastic lymphoma kinase (ALK), and induces apoptosis in ALK-positive anaplastic large cell lymphoma cells
-
Shi X, Franko B, Frantz C, et al. JSI-124 (cucurbitacin I) inhibits Janus kinase-3/signal transducer and activator of transcription-3 signalling, downregulates nucleophosmin-anaplastic lymphoma kinase (ALK), and induces apoptosis in ALK-positive anaplastic large cell lymphoma cells. Br J Haematol 2006;135:26-32.
-
(2006)
Br J Haematol
, vol.135
, pp. 26-32
-
-
Shi, X.1
Franko, B.2
Frantz, C.3
-
18
-
-
38949165127
-
Constitutively activated STAT3 promotes cell proliferation and survival in the activated B-cell subtype of diffuse large B-cell lymphomas
-
Ding BB, Yu JJ, Yu RY, et al. Constitutively activated STAT3 promotes cell proliferation and survival in the activated B-cell subtype of diffuse large B-cell lymphomas. Blood 2008;111:1515-1523.
-
(2008)
Blood
, vol.111
, pp. 1515-1523
-
-
Ding, B.B.1
Yu, J.J.2
Yu, R.Y.3
-
19
-
-
33645233157
-
Biallelic deletion within 16p13.13 including SOCS-1 in Karpas1106P mediastinal B-cell lymphoma line is associated with delayed degradation of JAK2 protein
-
Melzner I, Weniger MA, Bucur AJ, et al. Biallelic deletion within 16p13.13 including SOCS-1 in Karpas1106P mediastinal B-cell lymphoma line is associated with delayed degradation of JAK2 protein. Int J Cancer 2006;118:1941-1944.
-
(2006)
Int J Cancer
, vol.118
, pp. 1941-1944
-
-
Melzner, I.1
Weniger, M.A.2
Bucur, A.J.3
-
20
-
-
36148989576
-
Somatic hypermutation of SOCS1 in lymphocyte-predominant Hodgkin lymphoma is accompanied by high JAK2 expression and activation of STAT6
-
Mottok A, Renne C, Willenbrock K, et al. Somatic hypermutation of SOCS1 in lymphocyte-predominant Hodgkin lymphoma is accompanied by high JAK2 expression and activation of STAT6. Blood 2007;110:3387-3390.
-
(2007)
Blood
, vol.110
, pp. 3387-3390
-
-
Mottok, A.1
Renne, C.2
Willenbrock, K.3
-
21
-
-
33646382121
-
Mutations of the tumor suppressor gene SOCS-1 in classical Hodgkin lymphoma are frequent and associated with nuclear phospho-STAT5 accumulation
-
Weniger MA, Melzner I, Menz CK, et al. Mutations of the tumor suppressor gene SOCS-1 in classical Hodgkin lymphoma are frequent and associated with nuclear phospho-STAT5 accumulation. Oncogene 2006;25:2679-2684.
-
(2006)
Oncogene
, vol.25
, pp. 2679-2684
-
-
Weniger, M.A.1
Melzner, I.2
Menz, C.K.3
-
22
-
-
30644470844
-
JAK2 V617F mutation is uncommon in non-Hodgkin lymphomas
-
Lee JW, Soung YH, Kim SY, et al. JAK2 V617F mutation is uncommon in non-Hodgkin lymphomas. Leuk Lymphoma 2006;47:313-314.
-
(2006)
Leuk Lymphoma
, vol.47
, pp. 313-314
-
-
Lee, J.W.1
Soung, Y.H.2
Kim, S.Y.3
-
23
-
-
33644987681
-
Absence of the JAK2 V617F activating mutation in classical Hodgkin lymphoma and primary mediastinal B-cell lymphoma
-
Melzner I,Weniger MA, Menz CK, et al. Absence of the JAK2 V617F activating mutation in classical Hodgkin lymphoma and primary mediastinal B-cell lymphoma. Leukemia 2006;20:157-158.
-
(2006)
Leukemia
, vol.20
, pp. 157-158
-
-
Melzner, I.1
Weniger, M.A.2
Menz, C.K.3
-
24
-
-
0003477486
-
World Health Organization Classification of Tumours
-
Jaffe ES, Harris NL, Stein H, et al, eds, IARC Press: Lyon, France
-
Jaffe ES, Harris NL, Stein H, et al. (eds). World Health Organization Classification of Tumours. Pathology and Genetics of Tumours of Haematopoietic and Lymphoid Tissues. IARC Press: Lyon, France, 2001.
-
(2001)
Pathology and Genetics of Tumours of Haematopoietic and Lymphoid Tissues
-
-
-
25
-
-
40849126992
-
Correlation of high numbers of intratumoral FOXP3+ regulatory T cells with improved survival in germinal center-like diffuse large B-cell lymphoma, follicular lymphoma and classical Hodgkin's lymphoma
-
Tzankov A, Meier C, Hirschmann P, et al. Correlation of high numbers of intratumoral FOXP3+ regulatory T cells with improved survival in germinal center-like diffuse large B-cell lymphoma, follicular lymphoma and classical Hodgkin's lymphoma. Haematologica 2008;93:193-200.
-
(2008)
Haematologica
, vol.93
, pp. 193-200
-
-
Tzankov, A.1
Meier, C.2
Hirschmann, P.3
-
26
-
-
33646262907
-
Diffuse large B-cell lymphoma with over-expression of cyclin E substantiates poor standard treatment response and inferior outcome
-
Tzankov A, Gschwendtner A, Augustin F, et al. Diffuse large B-cell lymphoma with over-expression of cyclin E substantiates poor standard treatment response and inferior outcome. Clin Cancer Res 2006;12:2125-2132.
-
(2006)
Clin Cancer Res
, vol.12
, pp. 2125-2132
-
-
Tzankov, A.1
Gschwendtner, A.2
Augustin, F.3
-
27
-
-
12344325084
-
Aberrant expression of cell cycle regulators in Hodgkin and Reed-Sternberg cells of classical Hodgkin lymphoma
-
Tzankov A, Zimpfer A, Went P, et al. Aberrant expression of cell cycle regulators in Hodgkin and Reed-Sternberg cells of classical Hodgkin lymphoma. Mod Pathol 2005;18:90-96.
-
(2005)
Mod Pathol
, vol.18
, pp. 90-96
-
-
Tzankov, A.1
Zimpfer, A.2
Went, P.3
-
28
-
-
24644520560
-
Tissue microarray technology: Principles, pitfalls and perspectives-lessons learned from hematological malignancies
-
Tzankov A,Went P, Zimpfer A, et al. Tissue microarray technology: principles, pitfalls and perspectives-lessons learned from hematological malignancies. Exp Gerontol 2005;40:737-744.
-
(2005)
Exp Gerontol
, vol.40
, pp. 737-744
-
-
Tzankov, A.1
Went, P.2
Zimpfer, A.3
-
29
-
-
33846577311
-
Receiver operating characteristic curve inference from a sample with a limit of detection
-
Perkins NJ, Schisterman EF, Vexler A. Receiver operating characteristic curve inference from a sample with a limit of detection. Am J Epidemiol 2007;165:325-333.
-
(2007)
Am J Epidemiol
, vol.165
, pp. 325-333
-
-
Perkins, N.J.1
Schisterman, E.F.2
Vexler, A.3
-
30
-
-
44449145063
-
STAT3-mediated up-regulation of BLIMP1 Is coordinated with BCL6 down-regulation to control human plasma cell differentiation
-
Diehl SA, Schmidlin H, Nagasawa M, et al. STAT3-mediated up-regulation of BLIMP1 Is coordinated with BCL6 down-regulation to control human plasma cell differentiation. J Immunol 2008;180:4805-4815.
-
(2008)
J Immunol
, vol.180
, pp. 4805-4815
-
-
Diehl, S.A.1
Schmidlin, H.2
Nagasawa, M.3
-
31
-
-
20144369616
-
STAT5 regulates the self-renewal capacity and differentiation of human memory B cells and controls Bcl-6 expression
-
Scheeren FA, Naspetti M, Diehl S, et al. STAT5 regulates the self-renewal capacity and differentiation of human memory B cells and controls Bcl-6 expression. Nat Immunol 2005;6:303-313.
-
(2005)
Nat Immunol
, vol.6
, pp. 303-313
-
-
Scheeren, F.A.1
Naspetti, M.2
Diehl, S.3
-
32
-
-
10744228934
-
The molecular signature of mediastinal large B-cell lymphoma differs from that of other diffuse large B-cell lymphomas and shares features with classical Hodgkin lymphoma
-
Savage KJ, Monti S, Kutok JL, et al. The molecular signature of mediastinal large B-cell lymphoma differs from that of other diffuse large B-cell lymphomas and shares features with classical Hodgkin lymphoma. Blood 2003;102:3871-3879.
-
(2003)
Blood
, vol.102
, pp. 3871-3879
-
-
Savage, K.J.1
Monti, S.2
Kutok, J.L.3
-
33
-
-
0141672946
-
Molecular diagnosis of primary mediastinal B cell lymphoma identifies a clinically favorable subgroup of diffuse large B cell lymphoma related to Hodgkin lymphoma
-
Rosenwald A, Wright G, Leroy K, et al. Molecular diagnosis of primary mediastinal B cell lymphoma identifies a clinically favorable subgroup of diffuse large B cell lymphoma related to Hodgkin lymphoma. J Exp Med 2003;198:851-862.
-
(2003)
J Exp Med
, vol.198
, pp. 851-862
-
-
Rosenwald, A.1
Wright, G.2
Leroy, K.3
-
34
-
-
0037097818
-
The role of cytokines in classical Hodgkin lymphoma
-
Skinnider BF,Mak TW. The role of cytokines in classical Hodgkin lymphoma. Blood 2002;99:4283-4297.
-
(2002)
Blood
, vol.99
, pp. 4283-4297
-
-
Skinnider, B.F.1
Mak, T.W.2
-
35
-
-
20844433035
-
STAT3 is essential for Hodgkin lymphoma cell proliferation and is a target of tyrphostin AG17 which confers sensitization for apoptosis
-
Holtick U, Vockerodt M, Pinkert D, et al. STAT3 is essential for Hodgkin lymphoma cell proliferation and is a target of tyrphostin AG17 which confers sensitization for apoptosis. Leukemia 2005;19:936-944.
-
(2005)
Leukemia
, vol.19
, pp. 936-944
-
-
Holtick, U.1
Vockerodt, M.2
Pinkert, D.3
-
36
-
-
1942501550
-
Genomic profiling of peripheral T-cell lymphoma, unspecified, and anaplastic large T-cell lymphoma delineates novel recurrent chromosomal alterations
-
Zettl A, Rudiger T, Konrad MA, et al. Genomic profiling of peripheral T-cell lymphoma, unspecified, and anaplastic large T-cell lymphoma delineates novel recurrent chromosomal alterations. Am J Pathol 2004;164:1837-1848.
-
(2004)
Am J Pathol
, vol.164
, pp. 1837-1848
-
-
Zettl, A.1
Rudiger, T.2
Konrad, M.A.3
-
37
-
-
61349188589
-
-
Van Roosbroeck K, Lahortiga I, Cools J, et al. A novel t(4;9)(q21;p24) fuses SEC13A to JAK2 in nodular sclerosis Hodgkin Lymphoma. Haematologica 2007;92(s5):43.
-
Van Roosbroeck K, Lahortiga I, Cools J, et al. A novel t(4;9)(q21;p24) fuses SEC13A to JAK2 in nodular sclerosis Hodgkin Lymphoma. Haematologica 2007;92(s5):43.
-
-
-
-
38
-
-
33845865865
-
The STAT3 oncogene as a predictive marker of drug resistance
-
Barré B, Vigneron A, Perkins N, et al. The STAT3 oncogene as a predictive marker of drug resistance. Trends Mol Med 2007;13:4-11.
-
(2007)
Trends Mol Med
, vol.13
, pp. 4-11
-
-
Barré, B.1
Vigneron, A.2
Perkins, N.3
-
39
-
-
0142244231
-
Phosphorylation state-specific antibodies: Applications in investigative and diagnostic pathology
-
Mandell JW. Phosphorylation state-specific antibodies: applications in investigative and diagnostic pathology. Am J Pathol 2003;163:1687-1698.
-
(2003)
Am J Pathol
, vol.163
, pp. 1687-1698
-
-
Mandell, J.W.1
-
40
-
-
8644252736
-
Prediction of survival in follicular lymphoma based on molecular features of tumor-infiltrating immune cells
-
Dave SS, Wright G, Tan B, et al. Prediction of survival in follicular lymphoma based on molecular features of tumor-infiltrating immune cells. N Engl J Med 2004;351:2159-2169.
-
(2004)
N Engl J Med
, vol.351
, pp. 2159-2169
-
-
Dave, S.S.1
Wright, G.2
Tan, B.3
|