Genetic study of families affected with aggressive periodontitis

Periodontology 2000

Volumn 56, Issue 1, 2011, Pages 87-101

  Meng, Huanxin ^a   Ren, Xiuyun ^a   Tian, Yu ^a   Feng, Xianghui ^a   Xu, Li ^a   Zhang, Li ^a   Lu, Ruifang ^a   Shi, Dong ^a   Chen, Zhibing ^a  

^a NONE

Author keywords

[No Author keywords available]

Indexed keywords

AGGRESSIVE PERIODONTITIS; FAMILY HEALTH; FEMALE; GENETIC LINKAGE; GENETIC PREDISPOSITION; GENETICS; HUMAN; MALE; MICROBIOLOGY; PEDIGREE; REVIEW; TWINS;

AGGRESSIVE PERIODONTITIS; FAMILY HEALTH; FEMALE; GENETIC LINKAGE; GENETIC PREDISPOSITION TO DISEASE; HUMANS; MALE; PEDIGREE; TWIN STUDIES AS TOPIC;

EID: 79954583071     PISSN: 09066713     EISSN: 16000757     Source Type: Journal    
DOI: 10.1111/j.1600-0757.2010.00367.x     Document Type: Review

References (100)

1. Alaluusua S, Asikainen S, Lai CH. Intrafamilial transmission of Actinobacillus actinomycetemcomitans. J Periodontol 1991: 62: 207-210.
2. Arai H, Chihara T, Takahashi K, Nagai A, Akutsu I, Takashiba S, Nishimura F, Kurihara H, Murayama Y. Host defensive functions in a family manifesting early-onset periodontitis. J Periodontol 1996: 67: 433-442.
3. Asano H, Ishihara K, Nakagawa T, Yamada S, Okuda K. Relationship between transmission of Porphyromonas gingivalis and fimA type in spouses. J Periodontol 2003: 74: 1355-1360.
4. Asikainen S, Chen C, Slots J. Likelihood of transmitting Actinobacillus actinomycetemcomitans and Porphyromonas gingivalis in families with periodontitis. Oral Microbiol Immunol 1996: 11: 387-394.
5. Baer PN. The case for periodontosis as a clinical entity. J Periodontol 1971: 42: 516-520.
6. Beaty TH, Boughman JA, Yang P, Astemborski JA, Suzuki JB. Genetic analysis of juvenile periodontitis in families ascertained through an affected proband. Am J Hum Genet 1987: 40: 443-452.
7. Benjamin SD, Baer PN. Familial patterns of advanced alveolar bone loss in adolescence (periodontosis). Periodontics 1967: 5: 82-88.
8. Boughman JA, Astemborski JA, Suzuki JB. Phenotypic assessment of early onset periodontitis in sibships. J Clin Periodontol 1992: 19: 233-239.
9. Boughman JA, Beaty TH, Yang P, Goodman SB, Wooten RK, Suzuki JB. Problems of genetic model testing in early onset periodontitis. J Periodontol 1988: 59: 332-337.
10. Boughman JA, Halloran SL, Roulston D, Schwartz S, Suzuki JB, Weitkamp LR, Wenk RE, Wooten R, Cohen MM. An autosomal-dominant form of juvenile periodontitis: its localization to chromosome 4 and linkage to dentinogenesis imperfecta and Gc. J Craniofac Genet Dev Biol 1986: 6: 341-350.
11. Butler JH. A familial pattern of juvenile periodontitis (periodontosis). J Periodontol 1969: 40: 115-118.
12. Cohen DW, Goldman HM. Clinical observations on the modification of human oral tissue metabolism by local intraoral factors. Ann N Y Acad Sci 1960: 85: 68-95.
13. Corey LA, Nance WE, Hofstede P, Schenkein HA. Self-reported periodontal disease in a Virginia twin population. J Periodontol 1993: 64: 1205-1208.
14. Cortelli SC, Feres M, Rodrigues AA, Aquino DR, Shibli JA, Cortelli JR. Detection of Actinobacillus actinomycetemcomitans in unstimulated saliva of patients with chronic periodontitis. J Periodontol 2005: 76: 204-209.
15. Devlin B, Risch N. A comparison of linkage disequilibrium measures for fine-scale mapping. Genomics 1995: 29: 311-322.
16. Diehl SR, Wang Y, Brooks CN, Burmeister JA, Califano JV, Wang S, Schenkein HA. Linkage disequilibrium of interleukin-1 genetic polymorphisms with early-onset periodontitis. J Periodontol 1999: 70: 418-430.
17. Diehl SR, Wu T, Burmeister JA, Califano JV, Brooks CN, Tew JG, Schenkein HA. Evidence of a substantial genetic basis for IgG2 levels in families with aggressive periodontitis. J Dent Res 2003: 82: 708-712.
18. DiRienzo JM, Slots J. Genetic approach to the study of epidemiology and pathogenesis of Actinobacillus actinomycetemcomitans in localized juvenile periodontitis. Arch Oral Biol 1990: 35 (Suppl.): 79S-84S.
19. Dogan B, Kipalev AS, Okte E, Sultan N, Asikainen SE. Consistent intrafamilial transmission of Actinobacillus actinomycetemcomitans despite clonal diversity. J Periodontol 2008: 79: 307-315.
20. Drozdzik A, Kurzawski M, Safronow K, Banach J. Polymorphism in interleukin-1beta gene and the risk of periodontitis in a Polish population. Adv Med Sci 2006: 51 (Suppl. 1): 13-17.
21. Eger T, Zoller L, Müller HP, Hoffmann S, Lobinsky D. Potential diagnostic value of sampling oral mucosal surfaces for Actinobacillus actinomycetemcomitans in young adults. Eur J Oral Sci 1996: 104: 112-117.
22. Falconer DS. An introduction to quantitative genetics, 3rd edn. New York, NY: Longman Scientific and Technical, 1983: 163.
23. Feng X, Zhang L, Meng H, Xu L, Chen ZB, Shi D. Prevalence of putative periodontal microorganisms in Chinese patients with aggressive periodontitis. Zhonghua Kou Qiang Yi Xue Za Zhi 2006: 41: 344-347.
24. Fourel J. Periodontosis: a periodontal syndrome. J Periodontol 1972: 43: 240-255.
25. Fourel J. Periodontosis, juvenile periodontitis or Gottlieb syndrome? Report of 4 cases. J Periodontol 1974: 45: 234-237.
26. Fretwell LD, Leinbach TE, Wiley DO. Juvenile periodontitis: report of cases. J Am Dent Assoc 1982: 105: 1022-1025.
27. Fu Y, Korostoff JM, Fine DH, Wilson ME. Fc gamma receptor genes as risk markers for localized aggressive periodontitis in African-Americans. J Periodontol 2002: 73: 517-523.
28. Genco RJ, Van Dyke TE, Levine MJ, Nelson RD, Wilson ME. 1985 Kreshover lecture. Molecular factors influencing neutrophil defects in periodontal disease. J Dent Res 1986: 65: 1379-1391.
29. Glazier AM, Nadeau JH, Aitman TJ. Finding genes that underlie complex traits. Science 2002: 298: 2345-2349.
30. Hart TC, Kornman KS. Genetic factors in the pathogenesis of periodontitis. Periodontol 2000 1997: 14: 202-215.
31. Hart TC, Marazita ML, McCanna KM, Schenkein HA, Diehl SR. Reevaluation of the chromosome 4q candidate region for early onset periodontitis. Hum Genet 1993: 91: 416-422.
32. Hart TC, Marazita ML, Schenkein HA, Brooks CN, Gunsolley JG, Diehl SR. No female preponderance in juvenile periodontitis after correction for ascertainment bias. J Periodontol 1991: 62: 745-749.
33. Hart TC, Marazita ML, Schenkein HA, Diehl SR. Re-interpretation of the evidence for X-linked dominant inheritance of juvenile periodontitis. J Periodontol 1992: 63: 169-173.
34. Hodge SE. Linkage analysis versus association analysis: distinguishing between two models that explain disease-marker associations. Am J Hum Genet 1993: 53: 367-384.
35. Hodge SE. What association analysis can and cannot tell us about the genetics of complex disease. Am J Med Genet 1994: 54: 318-323.
36. Hodge PJ, Riggio MP, Kinane DF. No association with HLA-DQB1 in European Caucasians with early-onset periodontitis. Tissue Antigens 1999: 54: 205-207.
37. Hodge PJ, Teague PW, Wright AF, Kinane DF. Clinical and genetic analysis of a large North European Caucasian family affected by early-onset periodontitis. J Dent Res 2000: 79: 857-863.
38. Huang Y, Umeda M, Takeuchi Y, Ishizuka M, Yano-Higuchi K, Ishikawa I. Distribution of Bacteroides forsythus genotypes in a Japanese periodontitis population. Oral Microbiol Immunol 2003: 18: 208-214.
39. Johnson NW, Griffiths GS, Wilton JM, Maiden MF, Curtis MA, Gillett IR, Wilson DT, Sterne JA. Detection of high-risk groups and individuals for periodontal diseases. Evidence for the existence of high-risk groups and individuals and approaches to their detection. J Clin Periodontol 1988: 15: 276-282.
40. Jorgenson RJ, Levin LS, Hutcherson ST, Salinas CF. Periodontosis in sibs. Oral Surg Oral Med Oral Pathol 1975: 39: 396-402.
41. Kinane DF, Hodge P, Eskdale J, Ellis R, Gallagher G. Analysis of genetic polymorphisms at the interleukin-10 and tumour necrosis factor loci in early-onset periodontitis. J Periodontal Res 1999: 34: 379-386.
42. Kinane DF, Shiba H, Hart TC. The genetic basis of periodontitis. Periodontol 2000 2005: 39: 91-117.
43. Kobayashi N, Ishihara K, Sugihara N, Kusumoto M, Yakushiji M, Okuda K. Colonization pattern of periodontal bacteria in Japanese children and their mothers. J Periodontal Res 2008: 43: 156-161.
44. Kornman KS, Crane A, Wang HY, di Giovine FS, Newman MG, Pirk FW, Wilson TG Jr, Higginbottom FL, Duff GW. The interleukin-1 genotype as a severity factor in adult periodontal disease. J Clin Periodontol 1997: 24: 72-77.
45. Li Q, Meng H, Zhang L, Xu L, Chen Z, Shi D, Feng X, Zhu X, Zhao H, Cao C. Correlation between single nucleotide polymorphisms in a calprotectin subunit gene and risk of periodontitis in a Chinese population. Ann Hum Genet 2007: 71: 312-324.
46. Li Y, Xu L, Hasturk H, Kantarci A, DePalma SR, Van Dyke TE. Localized aggressive periodontitis is linked to human chromosome 1q25. Hum Genet 2004: 114: 291-297.
47. Li QY, Zhao HS, Meng HX, Zhang L, Xu L, Chen ZB. [The relationship between a nucleotide substitution of S100A8 gene and aggressive periodontitis]. Zhonghua Kou Qiang Yi Xue Za Zhi 2004: 39: 181-184 (Chinese).
48. Liu Z. Problems in autosomo recessive inheritance. Guoji Yi Chuan Xue Za Zhi 1979: 4: 231-236.
49. Long JC, Nance WE, Waring P, Burmeister JA, Ranney RR. Early onset periodontitis: a comparison and evaluation of two proposed modes of inheritance. Genet Epidemiol 1987: 4: 13-24.
50. Lopez NJ. Clinical, laboratory, and immunological studies of a family with a high prevalence of generalized prepubertal and juvenile periodontitis. J Periodontol 1992: 63: 457-468.
51. Manson JD. Juvenile periodontitis (periodontosis). Int Dent J 1977: 27: 114-118.
52. Marazita ML, Burmeister JA, Gunsolley JC, Koertge TE, Lake K, Schenkein HA. Evidence for autosomal dominant inheritance and race-specific heterogeneity in early-onset periodontitis. J Periodontol 1994: 65: 623-630.
53. Marazita ML, Lu H, Cooper ME, Quinn SM, Zhang J, Burmeister JA, Califano JV, Pandey JP, Schenkein HA, Tew JG. Genetic segregation analyses of serum IgG2 levels. Am J Hum Genet 1996: 58: 1042-1049.
54. Melnick M, Shields ED, Bixler D. Periodontosis: a phenotypic and genetic analysis. Oral Surg Oral Med Oral Pathol 1976: 42: 32-41.
55. Meng H, Xu L, Li Q, Han J, Zhao Y. Determinants of host susceptibility in aggressive periodontitis. Periodontol 2000 2007: 43: 133-159.
56. Michalowicz BS, Aeppli DP, Kuba RK, Bereuter JE, Conry JP, Segal NL, Bouchard TJ Jr, Pihlstrom BL. A twin study of genetic variation in proportional radiographic alveolar bone height. J Dent Res 1991: 70: 1431-1435.
57. Michalowicz BS, Aeppli D, Virag JG, Klump DG, Hinrichs JE, Segal NL, Bouchard TJ Jr, Pihlstrom BL. Periodontal findings in adult twins. J Periodontol 1991: 62: 293-299.
58. Michalowicz BS, Diehl SR, Gunsolley JC, Sparks BS, Brooks CN, Koertge TE, Califano JV, Burmeister JA, Schenkein HA. Evidence of a substantial genetic basis for risk of adult periodontitis. J Periodontol 2000: 71: 1699-1707.
59. Michalowicz BS, Wolff LF, Klump D, Hinrichs JE, Aeppli DM, Bouchard TJ Jr, Pihlstrom BL. Periodontal bacteria in adult twins. J Periodontol 1999: 70: 263-273.
60. Michel J, Gonzales JR, Wunderlich D, Diete A, Herrmann JM, Meyle J. Interleukin-4 polymorphisms in early onset periodontitis. J Clin Periodontol 2001: 28: 483-488.
61. Monaghan F, Corcos A. On the origins of the Mendelian laws. J Hered 1984: 75: 67-69.
62. Müller HP, Lange DE, Müller RF. Actinobacillus actinomycetemcomitans recovery from extracrevicular locations of the mouth. Oral Microbiol Immunol 1993: 8: 344-348.
63. Nishimura F, Nagai A, Kurimoto K, Isoshima O, Takashiba S, Kobayashi M, Akutsu I, Kurihara H, Nomura Y, Murayama Y, Ohta H, Kato K. A family study of a mother and daughter with increased susceptibility to early-onset periodontitis: microbiological, immunological, host defensive, and genetic analyses. J Periodontol 1990: 61: 755-762.
64. Okada M, Hayashi F, Soda Y, Zhong X, Miura K, Kozai K. Intra-familial distribution of nine putative periodontopathogens in dental plaque samples analyzed by PCR. J Oral Sci 2004: 46: 149-156.
65. Page RC, Altman LC, Ebersole JL, Vandesteen GE, Dahlberg WH, Williams BL, Osterberg SK. Rapidly progressive periodontitis. A distinct clinical condition. J Periodontol 1983: 54: 197-209.
66. Page RC, Beck JD. Risk assessment for periodontal diseases. Int Dent J 1997: 47: 61-87.
67. Page RC, Bowen T, Altman L, Vandesteen E, Ochs H, Mackenzie P, Osterberg S, Engel LD, Williams BL. Prepubertal periodontitis. I. Definition of a clinical disease entity. J Periodontol 1983: 54: 257-271.
68. Page RC, Vandesteen GE, Ebersole JL, Williams BL, Dixon IL, Altman LC. Clinical and laboratory studies of a family with a high prevalence of juvenile periodontitis. J Periodontol 1985: 56: 602-610.
69. Preus HR, Zambon JJ, Dunford RG, Genco RJ. The distribution and transmission of Actinobacillus actinomycetemcomitans in families with established adult periodontitis. J Periodontol 1994: 65: 2-7.
70. Pritchard JK, Przeworski M. Linkage disequilibrium in humans: models and data. Am J Hum Genet 2001: 69: 1-14.
71. Ren XY, Xu L, Meng HX, Zhao HS, Lu RF, Chen ZB, Feng XH, Shi D, Zhang L, Tian Y. Family-based association analysis of S100A8 genetic polymorphisms with aggressive periodontitis. J Periodontal Res 2009: 44: 184-192.
72. Risch N, Merikangas K. The future of genetic studies of complex human diseases. Science 1996: 273: 1516-1517.
73. Saarela M, von Troil-Linden B, Torkko H, Stucki AM, Alaluusua S, Jousimies-Somer H, Asikainen S. Transmission of oral bacterial species between spouses. Oral Microbiol Immunol 1993: 8: 349-354.
74. Saxén L. Heredity of juvenile periodontitis. J Clin Periodontol 1980: 7: 276-288.
75. Saxén L, Nevanlinna HR. Autosomal recessive inheritance of juvenile periodontitis: test of a hypothesis. Clin Genet 1984: 25: 332-335.
76. Sbordone L, Ramaglia L, Bucci E. Generalized juvenile periodontitis: report of a familial case followed for 5years. J Periodontol 1990: 61: 590-596.
77. Shapira L, Schlesinger M, Bimstein E. Possible autosomal-dominant inheritance of prepubertal periodontitis in an extended kindred. J Clin Periodontol 1997: 24: 388-393.
78. Shapira L, Stabholz A, Rieckmann P, Kruse N. Genetic polymorphism of the tumor necrosis factor (TNF)-alpha promoter region in families with localized early-onset periodontitis. J Periodontal Res 2001: 36: 183-186.
79. Slots J, Ting M. Actinobacillus actinomycetemcomitans and Porphyromonas gingivalis in human periodontal disease: occurrence and treatment. Periodontol 2000 1999: 20: 82-121.
80. Spektor MD, Vandesteen GE, Page RC. Clinical studies of one family manifesting rapidly progressive, juvenile and prepubertal periodontitis. J Periodontol 1985: 56: 93-101.
81. Spielman RS, McGinnis RE, Ewens WJ. Transmission test for linkage disequilibrium: the insulin gene region and insulin-dependent diabetes mellitus (IDDM). Am J Hum Genet 1993: 52: 506-516.
82. van Steenbergen TJ, Petit MD, Scholte LH, van der Velden U, de Graaff J. Transmission of Porphyromonas gingivalis between spouses. J Clin Periodontol 1993: 20: 340-345.
83. Sun JL, Meng HX, Cao CF, Tachi Y, Shinohara M, Ueda M, Imai H, Ohura K. Relationship between vitamin D receptor gene polymorphism and periodontitis. J Periodontal Res 2002: 37: 263-267.
84. Sussman HI, Baer PN. Three generations of periodontosis: case report. Ann Dent 1978: 37: 8-11.
85. Takahashi K, Takigawa M, Hara H, Nagai A, Takashiba S, Nishimura F, Chihara T, Ohyama H, Satoh N, Kurihara H, Murayama Y. Clinical and laboratory studies on a patient with early onset periodontitis and her family members. A case report. J Periodontol 1995: 66: 403-412.
86. Tamura K, Nakano K, Hayashibara T, Nomura R, Fujita K, Shintani S, Ooshima T. Distribution of 10 periodontal bacteria in saliva samples from Japanese children and their mothers. Arch Oral Biol 2006: 51: 371-377.
87. Tinoco EM, Sivakumar M, Preus HR. The distribution and transmission of Actinobacillus actinomycetemcomitans in families with localized juvenile periodontitis. J Clin Periodontol 1998: 25: 99-105.
88. Townsend GC, Aldred MJ, Bartold PM. Genetic aspects of dental disorders. Aust Dent J 1998: 43: 269-286.
89. Trevilatto PC, Tramontina VA, Machado MA, Goncalves RB, Sallum AW, Line SR. Clinical, genetic and microbiological findings in a Brazilian family with aggressive periodontitis. J Clin Periodontol 2002: 29: 233-239.
90. Tuite-McDonnell M, Griffen AL, Moeschberger ML, Dalton RE, Fuerst PA, Leys EJ. Concordance of Porphyromonas gingivalis colonization in families. J Clin Microbiol 1997: 35: 455-461.
91. Umeda M, Miwa Z, Takeuchi Y, Ishizuka M, Huang Y, Noguchi K, Tanaka M, Takagi Y, Ishikawa I. The distribution of periodontopathic bacteria among Japanese children and their parents. J Periodontal Res 2004: 39: 398-404.
92. Van Dyke TE, Schweinebraten M, Cianciola LJ, Offenbacher S, Genco RJ. Neutrophil chemotaxis in families with localized juvenile periodontitis. J Periodontal Res 1985: 20: 503-514.
93. Vandesteen GE, Altman LC, Page RC. Peripheral blood leukocyte abnormalities and periodontal disease. A family study. J Periodontol 1981: 52: 174-180.
94. Vandesteen GE, Altman LC, Spektor M, Williams BL, Ebersole J, Page RC. Leukocyte function, microflora, and antibody studies of four families with periodontitis. J Periodontal Res 1982: 17: 498-499.
95. Vandesteen GE, Williams BL, Ebersole JL, Altman LC, Page RC. Clinical, microbiological and immunological studies of a family with a high prevalence of early-onset periodontitis. J Periodontol 1984: 55: 159-169.
96. Williams BL, Ebersole JL, Spektor MD, Page RC. Assessment of serum antibody patterns and analysis of subgingival microflora of members of a family with a high prevalence of early-onset periodontitis. Infect Immun 1985: 49: 742-750.
97. Wilton JM, Griffiths GS, Curtis MA, Maiden MF, Gillett IR, Wilson DT, Sterne JA, Johnson NW. Detection of high-risk groups and individuals for periodontal diseases. Systemic predisposition and markers of general health. J Clin Periodontol 1988: 15: 339-346.
98. van Winkelhoff AJ, Rijnsburger MC, van der Velden U. Clonal stability of Porphyromonas gingivalis in untreated periodontitis. J Clin Periodontol 2008: 35: 674-679.
99. Ximenez-Fyvie LA, Haffajee AD, Socransky SS. Microbial composition of supra- and subgingival plaque in subjects with adult periodontitis. J Clin Periodontol 2000: 27: 722-732.
100. Xu L, Meng HX, Tian Y, Zhang L, Feng XH, Zhang G. Evaluation of root abnormity in patients with aggressive periodontitis. Zhonghua Kou Qiang Yi Xue Za Zhi 2009: 44: 266-269.