Homology model versus X-ray structure in receptor-based drug design: A retrospective analysis with the dopamine D3 receptor

ACS Medicinal Chemistry Letters

Volumn 2, Issue 4, 2011, Pages 293-297

  Levoin, Nicolas ^a   Calmels, Thierry ^a   Krief, Stéphane ^a   Danvy, Denis ^a   Berrebi Bertrand, Isabelle ^a   Lecomte, Jeanne Marie ^a   Schwartz, Jean Charles ^a   Capet, Marc ^a  

^a Bioprojet Biotech   (France)

Author keywords

docking; Dopamine D3 receptor; G protein coupled receptors; homology model; lead optimization

Indexed keywords

DOPAMINE 3 RECEPTOR; G PROTEIN COUPLED RECEPTOR;

ARTICLE; BINDING SITE; CRYSTAL STRUCTURE; MOLECULAR DOCKING; PRIORITY JOURNAL; PROTEIN CONFORMATION; RETROSPECTIVE STUDY; X RAY CRYSTALLOGRAPHY;

EID: 79954578394     PISSN: None     EISSN: 19485875     Source Type: Journal    
DOI: 10.1021/ml100288q     Document Type: Article

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