DNA-based strategies for blocking HMGB1 cytokine activity: Design, synthesis and preliminary in vitro/in vivo assays of DNA and DNA-like duplexes

Molecular BioSystems

Volumn 7, Issue 5, 2011, Pages 1742-1752

  Musumeci, Domenica ^a   Bucci, Enrico M ^a   Roviello, Giovanni N ^a   Sapio, Roberto ^b   Valente, Margherita ^b   Moccia, Maria ^a   Bianchi, Marco E ^c   Pedone, Carlo ^a  

^a CNR   (Italy)

^b Bionucleon Srl   (Italy)

^c SAN RAFFAELE HOSPITAL   (Italy)

Author keywords

[No Author keywords available]

Indexed keywords

CIRCULAR DNA; DNA; HETERODUPLEX; HIGH MOBILITY GROUP B1 PROTEIN; KINKED DNA; LIPOPOLYSACCHARIDE; PEPTIDE NUCLEIC ACID;

ANIMAL; ARTICLE; BAGG ALBINO MOUSE; BINDING SITE; CELL LINE; CELL MOTION; CELL PROLIFERATION; CHEMICAL STRUCTURE; CHEMICALLY INDUCED DISORDER; CHEMISTRY; CONFORMATION; DRUG ANTAGONISM; DRUG EFFECT; ENDOTOXEMIA; MALE; METABOLISM; MORTALITY; MOUSE; NUCLEOTIDE SEQUENCE; PROTEIN BINDING; PROTEIN TERTIARY STRUCTURE; SURVIVAL RATE; TIME;

ANIMALS; BASE SEQUENCE; BINDING SITES; CELL LINE; CELL MOVEMENT; CELL PROLIFERATION; DNA; DNA, CIRCULAR; ENDOTOXEMIA; HMGB1 PROTEIN; LIPOPOLYSACCHARIDES; MALE; MICE; MICE, INBRED BALB C; MODELS, MOLECULAR; MOLECULAR STRUCTURE; NUCLEIC ACID CONFORMATION; NUCLEIC ACID HETERODUPLEXES; PEPTIDE NUCLEIC ACIDS; PROTEIN BINDING; PROTEIN STRUCTURE, TERTIARY; SURVIVAL RATE; TIME FACTORS;

MUS;

EID: 79954550870     PISSN: 1742206X     EISSN: 17422051     Source Type: Journal    
DOI: 10.1039/c1mb05009e     Document Type: Article

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