Conformational difference in HMGB1 proteins of human neutrophils and lymphocytes revealed by epitope mapping of a monoclonal antibody

Journal of Biochemistry

Volumn 136, Issue 2, 2004, Pages 155-162

  Ito, Ichiaki ^a   Mitsuoka, Nobuyoshi ^a   Sobajima, Junko ^b   Uesugi, Hiroko ^c   Ozaki, Shoichi ^d   Ohya, Kazuhiko ^e   Yoshida, Michiteru ^a  

^a TOKYO UNIVERSITY OF SCIENCE   (Japan)

^b KYOTO UNIVERSITY GRADUATE SCHOOL OF MEDICINE   (Japan)

^c Saiseikai Noe Hospital   (Japan)

^d ST MARIANNA UNIVERSITY SCHOOL OF MEDICINE   (Japan)

^e Medical & Biological Laboratories Co Ltd   (Japan)

Author keywords

Epitope mapping; HMGB1; Neutrophil; Nonhistone chromosomal protein; Protein conformation

Indexed keywords

EPITOPE; HIGH MOBILITY GROUP B1 PROTEIN; HIGH MOBILITY GROUP B1 PROTEIN ANTIBODY; HIGH MOBILITY GROUP B2 PROTEIN; HIGH MOBILITY GROUP B2 PROTEIN ANTIBODY; MONOCLONAL ANTIBODY; UNCLASSIFIED DRUG;

AMINO ACID SEQUENCE; ANTIBODY DETECTION; ANTIGEN ANTIBODY REACTION; ANTIGEN RECOGNITION; ARTICLE; AUTOIMMUNE HEPATITIS; CONFORMATIONAL TRANSITION; CONTROLLED STUDY; EPITOPE MAPPING; HUMAN; HUMAN CELL; IMMUNOREACTIVITY; LYMPHOCYTE; NEUTROPHIL; PROTEIN CONFORMATION; PROTEIN LOCALIZATION; PROTEIN STRUCTURE; RHEUMATIC DISEASE; ULCERATIVE COLITIS;

AMINO ACID SEQUENCE; ANIMALS; ANTIBODIES, MONOCLONAL; BINDING, COMPETITIVE; BLOTTING, NORTHERN; BLOTTING, WESTERN; CHROMOSOMES; CYTOPLASM; DOSE-RESPONSE RELATIONSHIP, DRUG; ELECTROPHORESIS, POLYACRYLAMIDE GEL; ENZYME-LINKED IMMUNOSORBENT ASSAY; EPITOPE MAPPING; EPITOPES; ESCHERICHIA COLI; HMGB1 PROTEIN; HUMANS; LYMPHOCYTES; MODELS, MOLECULAR; MOLECULAR SEQUENCE DATA; MUTATION; NEUTROPHILS; PEPTIDE LIBRARY; PEPTIDES; PROTEIN CONFORMATION; SWINE;

EUKARYOTA;

EID: 4644281311     PISSN: 0021924X     EISSN: None     Source Type: Journal    
DOI: 10.1093/jb/mvh107     Document Type: Article

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