Bent oligonucleotide duplexes as HMGB1 inhibitors: A comparative study

Nucleosides, Nucleotides and Nucleic Acids

Volumn 26, Issue 10-12, 2007, Pages 1447-1450

  Musumeci, D ^a   Roviello, G N ^a   Moccia, M ^a   Pedone, C ^a   Bucci, E M ^b   Sapio, R ^b   Valente, M ^b   Fumero, S ^c  

^a CNR   (Italy)

^b Bionucleon Srl   (Italy)

^c Creabilis Therapeutics SpA   (Italy)

Author keywords

Bent duplexes; HMGB1 inhibition; LNA

Indexed keywords

ADENINE; CURVED DNA; DOUBLE STRANDED DNA; HIGH MOBILITY GROUP B1 PROTEIN; HIGH MOBILITY GROUP B1 PROTEIN INHIBITOR; OLIGONUCLEOTIDE; POLYNUCLEOTIDE; PROTEIN INHIBITOR; UNCLASSIFIED DRUG;

ARTICLE; CHIMERA; CIRCULAR DICHROISM; COMPARATIVE STUDY; DNA HELIX; DRUG ACTIVITY; IC 50; INFLAMMATION; INHIBITION KINETICS; MOLECULE; SPECTROSCOPY; THERMODYNAMICS; TITRIMETRY;

DNA; HMGB1 PROTEIN; HUMANS; OLIGONUCLEOTIDES;

EID: 36949017074     PISSN: 15257770     EISSN: 15322335     Source Type: Journal    
DOI: 10.1080/15257770701542330     Document Type: Article

References (4)

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4. Kurreck, J.; Wyszko, E.; Gillen, C.; Erdmann, V.A. Design of antisense oligonucleotides stabilized by locked nucleic acids. Nucleic Acids Res. 2002, 30(9), 1911-1918.