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Volumn 300, Issue 4, 2011, Pages 1017-1025

Blocking core fucosylation of TGF-β1 receptors downregulates their functions and attenuates the epithelial-mesenchymal transition of renal tubular cells

Author keywords

6 fucosyltransferase; A 1; Renal fibrosis; Renal tubular epithelial

Indexed keywords

ALPHA 1,6 FUCOSYLTRANSFERASE; FUCOSYLTRANSFERASE; SMAD2 PROTEIN; SMAD3 PROTEIN; SMALL INTERFERING RNA; TRANSFORMING GROWTH FACTOR BETA RECEPTOR 1; TRANSFORMING GROWTH FACTOR BETA RECEPTOR 2; TRANSFORMING GROWTH FACTOR BETA1; UNCLASSIFIED DRUG;

EID: 79954546159     PISSN: 1931857X     EISSN: 15221466     Source Type: Journal    
DOI: 10.1152/ajprenal.00426.2010     Document Type: Article
Times cited : (65)

References (38)
  • 1
    • 0028109801 scopus 로고
    • Transforming growth factor beta in tissue fibrosis
    • Border WA, Noble NA. Transforming growth factor beta in tissue fibrosis. N Engl J Med 331: 1286-1292, 1994.
    • (1994) N Engl J Med , vol.331 , pp. 1286-1292
    • Border, W.A.1    Noble, N.A.2
  • 3
    • 0036786834 scopus 로고    scopus 로고
    • TGF-fj signaling in renal disease
    • Bottinger EP, Bitzer M. TGF-fj signaling in renal disease. J Am Soc Nephrol 13: 2600-2610, 2002.
    • (2002) J Am Soc Nephrol , vol.13 , pp. 2600-2610
    • Bottinger, E.P.1    Bitzer, M.2
  • 4
    • 34250733867 scopus 로고    scopus 로고
    • The role of tubular epithelial-mesenchymal transition in progressive kidney disease
    • Burns WC, Kantharidis P, Thomas MC. The role of tubular epithelial-mesenchymal transition in progressive kidney disease. Cells Tissues Organs 185: 222-223, 2007.
    • (2007) Cells Tissues Organs , vol.185 , pp. 222-223
    • Burns, W.C.1    Kantharidis, P.2    Thomas, M.C.3
  • 5
    • 0028946013 scopus 로고
    • Glycobiology: "towards understanding the function of sugars"
    • Dwek RA. Glycobiology: "towards understanding the function of sugars." Biochem Soc Trans 23: 1-25, 1995.
    • (1995) Biochem Soc Trans , vol.23 , pp. 1-25
    • Dwek, R.A.1
  • 6
    • 0032842887 scopus 로고    scopus 로고
    • Transforming growth factor- fj regulates tubular epithelial-myofibro-blast transdifferentiation in vitro
    • Fan JM, Ng YY, Hill PA, Nikolic-Paterson DJ, Mu W, Atkins RC, Lan HY. Transforming growth factor- fj regulates tubular epithelial-myofibro-blast transdifferentiation in vitro. Kidney Int 56: 1455-1467, 1999.
    • (1999) Kidney Int , vol.56 , pp. 1455-1467
    • Fan, J.M.1    Ng, Y.Y.2    Hill, P.A.3    Nikolic-Paterson, D.J.4    Mu, W.5    Atkins, R.C.6    Lan, H.Y.7
  • 8
    • 0036677372 scopus 로고    scopus 로고
    • Glycosylation defining cancer malignancy: New wine in an old bottle
    • Hakomori S. Glycosylation defining cancer malignancy: new wine in an old bottle. Proc Natl Acad Sci USA 99: 10231-10233, 2002.
    • (2002) Proc Natl Acad Sci USA , vol.99 , pp. 10231-10233
    • Hakomori, S.1
  • 9
    • 0002779849 scopus 로고    scopus 로고
    • Therapy with antisense TGF-fj1 oligodeoxynucleotides reduces kidney weight and matrix mRNAs in diabetic mice
    • Han DC, Hoffman BB, Hong SW, Guo J, Ziyadeh FN. Therapy with antisense TGF-fj1 oligodeoxynucleotides reduces kidney weight and matrix mRNAs in diabetic mice. Am J Physiol Renal Physiol 278: F628-F634, 2000.
    • (2000) Am J Physiol Renal Physiol , vol.278
    • Han, D.C.1    Hoffman, B.B.2    Hong, S.W.3    Guo, J.4    Ziyadeh, F.N.5
  • 10
    • 0035014583 scopus 로고    scopus 로고
    • Increased glomerular and tubular expression of transforming growth factor-31, its type II receptor, and activation of the Smad signaling pathway in the db/db mouse
    • Hong SW, Isono M, Chen S, Iglesiasde la Cruz MC, Han DC, Ziyadeh FN. Increased glomerular and tubular expression of transforming growth factor-31, its type II receptor, and activation of the Smad signaling pathway in the db/db mouse. Am J Pathol 158: 1653-1663, 2001.
    • (2001) Am J Pathol , vol.158 , pp. 1653-1663
    • Hong, S.W.1    Isono, M.2    Chen, S.3    la Cruz, M.C.I.4    Han, D.C.5    Ziyadeh, F.N.6
  • 11
    • 56949098199 scopus 로고    scopus 로고
    • E-cadherin core fucosylation regulates nuclear beta-catenin accumulation in lung cancer cells
    • Hu P, Shi B, Geng F, Zhang C, Wu W, Wu XZ. E-cadherin core fucosylation regulates nuclear beta-catenin accumulation in lung cancer cells. Glycoconj J 25: 843-850, 2008.
    • (2008) Glycoconj J , vol.25 , pp. 843-850
    • Hu, P.1    Shi, B.2    Geng, F.3    Zhang, C.4    Wu, W.5    Wu, X.Z.6
  • 12
    • 2342650030 scopus 로고    scopus 로고
    • Neilson EG. Mechanisms of tubulointerstitial fibrosis
    • Iwano M, Neilson EG. Mechanisms of tubulointerstitial fibrosis. Curr Opin Nephrol Hypertens 13: 279-284, 2004.
    • (2004) Curr Opin Nephrol Hypertens , vol.13 , pp. 279-284
    • Iwano, M.1
  • 13
    • 40449103715 scopus 로고    scopus 로고
    • Identification of target proteins of glycosyltransferases using functional glycomics by gene expression regulation
    • Kondo A. Identification of target proteins of glycosyltransferases using functional glycomics by gene expression regulation. Trends Glycosci Glycotechnol 19: 247-256, 2007.
    • (2007) Trends Glycosci Glycotechnol , vol.19 , pp. 247-256
    • Kondo, A.1
  • 14
    • 59849109196 scopus 로고    scopus 로고
    • Facile construction of unmarked deletion mutants in Burkholderia pseudomallei using sacB counter-selection in sucrose-resistant and sucrose-sensitive isolates
    • Logue CA, Peak IR, Beacham IR. Facile construction of unmarked deletion mutants in Burkholderia pseudomallei using sacB counter-selection in sucrose-resistant and sucrose-sensitive isolates. J Microbiol Methods 76: 320-323, 2009.
    • (2009) J Microbiol Methods , vol.76 , pp. 320-323
    • Logue, C.A.1    Peak, I.R.2    Beacham, I.R.3
  • 16
    • 49749141107 scopus 로고    scopus 로고
    • N-glycan fucosylation of epidermal growth factor receptor modulates receptor activity and sensitivity to epidermal growth factor receptor tyrosine kinase inhibitor
    • Matsumoto K, Yokote H, Arao T, Maegawa M, Tanaka K, Fujita Y, Shimizu C, Hanafusa T, Fujiwara Y, Nishio K. N-glycan fucosylation of epidermal growth factor receptor modulates receptor activity and sensitivity to epidermal growth factor receptor tyrosine kinase inhibitor. Cancer Sci 99: 1611-1617, 2008.
    • (2008) Cancer Sci , vol.99 , pp. 1611-1617
    • Matsumoto, K.1    Yokote, H.2    Arao, T.3    Maegawa, M.4    Tanaka, K.5    Fujita, Y.6    Shimizu, C.7    Hanafusa, T.8    Fujiwara, Y.9    Nishio, K.10
  • 17
    • 0026557672 scopus 로고
    • Production of extracellular matrix by glomerular epithelial cells is regulated by transforming growth factor-31
    • Nakamura T, Miller D, Ruoslahti E, Border WA. Production of extracellular matrix by glomerular epithelial cells is regulated by transforming growth factor-31. Kidney Int 41: 1213-1221, 1992.
    • (1992) Kidney Int , vol.41 , pp. 1213-1221
    • Nakamura, T.1    Miller, D.2    Ruoslahti, E.3    Border, W.A.4
  • 19
    • 33748195979 scopus 로고    scopus 로고
    • Glycosylation in cellular mechanisms of health and disease
    • Ohtsubo K, Marth JD. Glycosylation in cellular mechanisms of health and disease. Cell 126: 855-867, 2006.
    • (2006) Cell , vol.126 , pp. 855-867
    • Ohtsubo, K.1    Marth, J.D.2
  • 22
    • 30744478450 scopus 로고    scopus 로고
    • The differential role of Smad2 and Smad3 in the regulation of pro-fibrotic TGFfj1 responses in human proximal-tubule epithelial cells
    • Phanish MK, Wahab NA, Colville-Nash P, Hendry BM, Dockrell MEC. The differential role of Smad2 and Smad3 in the regulation of pro-fibrotic TGFfj1 responses in human proximal-tubule epithelial cells. Biochem J 393: 601-607, 2006.
    • (2006) Biochem J , vol.393 , pp. 601-607
    • Phanish, M.K.1    Wahab, N.A.2    Colville-Nash, P.3    Hendry, B.M.4    Dockrell, M.E.C.5
  • 23
    • 0346727324 scopus 로고    scopus 로고
    • Targeted disruption of TGF-fj1/Smad3 signaling protects against renal tubulointerstitial fibrosis induced by unilateral ureteral obstruction
    • Sato M, Muragaki Y, Saika S, Roberts AB, Ooshima A. Targeted disruption of TGF-fj1/Smad3 signaling protects against renal tubulointerstitial fibrosis induced by unilateral ureteral obstruction. J Clin Invest 112: 1486-1494, 2003.
    • (2003) J Clin Invest , vol.112 , pp. 1486-1494
    • Sato, M.1    Muragaki, Y.2    Saika, S.3    Roberts, A.B.4    Ooshima, A.5
  • 24
    • 0035179085 scopus 로고    scopus 로고
    • Chemical and biological strategies for engineering cell surface glycosylation
    • Saxon E, Bertozzi CR. Chemical and biological strategies for engineering cell surface glycosylation. Annu Rev Cell Dev Biol 17: 1-23, 2001.
    • (2001) Annu Rev Cell Dev Biol , vol.17 , pp. 1-23
    • Saxon, E.1    Bertozzi, C.R.2
  • 25
    • 66149154666 scopus 로고    scopus 로고
    • Inhibition of glycosyltransferase activities as the basis for drug development
    • Schutzbach J, Brockhausen I. Inhibition of glycosyltransferase activities as the basis for drug development. Methods Mol Biol 534: 359-373, 2009.
    • (2009) Methods Mol Biol , vol.534 , pp. 359-373
    • Schutzbach, J.1    Brockhausen, I.2
  • 26
    • 0029924637 scopus 로고    scopus 로고
    • Neutralization of TGF-beta by anti-TGF-beta antibody attenuates kidney hypertrophy and the enhanced extracellular matrix gene expression in STZ-induced diabetic mice
    • Sharma K, Jin Y, Guo J, Ziyadeh FN. Neutralization of TGF-beta by anti-TGF-beta antibody attenuates kidney hypertrophy and the enhanced extracellular matrix gene expression in STZ-induced diabetic mice. Diabetes 45: 522-530, 1996.
    • (1996) Diabetes , vol.45 , pp. 522-530
    • Sharma, K.1    Jin, Y.2    Guo, J.3    Ziyadeh, F.N.4
  • 27
    • 0028965480 scopus 로고
    • On the progression of chronic disease
    • Strutz F, Muller GA. On the progression of chronic disease. Nephron 69: 371-379, 1995.
    • (1995) Nephron , vol.69 , pp. 371-379
    • Strutz, F.1    Muller, G.A.2
  • 29
    • 68249103612 scopus 로고    scopus 로고
    • Core fucose and bisecting GlcNAc, the direct modifiers of the N-glycan core: Their functions and target proteins
    • Takahashi M, Kuroki Y, Ohtsubo K, Taniguchi N. Core fucose and bisecting GlcNAc, the direct modifiers of the N-glycan core: their functions and target proteins. Carbohydr Res 344: 1387-1390, 2009.
    • (2009) Carbohydr Res , vol.344 , pp. 1387-1390
    • Takahashi, M.1    Kuroki, Y.2    Ohtsubo, K.3    Taniguchi, N.4
  • 30
    • 0035260226 scopus 로고    scopus 로고
    • A glycomic approach to the identification and characterization of glycoprotein function in cells trans-fected with glycosyltransferase genes
    • Taniguchi N, Ekuni A, Ko JH, Miyoshi E, Ikeda Y, Ihara Y, Ni-shikawa A, Honke K, Takahashi M. A glycomic approach to the identification and characterization of glycoprotein function in cells trans-fected with glycosyltransferase genes. Proteomics 1: 239-247, 2001.
    • (2001) Proteomics , vol.1 , pp. 239-247
    • Taniguchi, N.1    Ekuni, A.2    Ko, J.H.3    Miyoshi, E.4    Ikeda, Y.5    Ihara, Y.6    Ni-Shikawa, A.7    Honke, K.8    Takahashi, M.9
  • 31
    • 61849122930 scopus 로고    scopus 로고
    • The second golden age of glycomics: From functional glycomics to clinical applications
    • Taniguchi N, Hancock W, Lubman DM, Rudd PM. The second golden age of glycomics: from functional glycomics to clinical applications. J Proteome Res 8: 425-426, 2009.
    • (2009) J Proteome Res , vol.8 , pp. 425-426
    • Taniguchi, N.1    Hancock, W.2    Lubman, D.M.3    Rudd, P.M.4
  • 33
    • 0027318961 scopus 로고
    • Biological roles of oligosaccharides: All of the theories are correct
    • Varki A. Biological roles of oligosaccharides: all of the theories are correct. Glycobiology 3: 97-130, 1993.
    • (1993) Glycobiology , vol.3 , pp. 97-130
    • Varki, A.1
  • 35
    • 0030897673 scopus 로고    scopus 로고
    • Purification and cDNA cloning of GDP-L-Fuc:N-acetyl-beta-D-glucosaminide alpha1^6fucosyltransferase-1-6 FucT) from human gastric cancer MKN45 cells
    • Yanagidani S, Uozumi N, Ihara Y, Miyoshi E, Yamaguchi N, Taniguchi N. Purification and cDNA cloning of GDP-L-Fuc:N-acetyl-beta-D-glucosaminide alpha1^6fucosyltransferase-1-6 FucT) from human gastric cancer MKN45 cells. J Biochem 121: 626-632, 1997.
    • (1997) J Biochem , vol.121 , pp. 626-632
    • Yanagidani, S.1    Uozumi, N.2    Ihara, Y.3    Miyoshi, E.4    Yamaguchi, N.5    Taniguchi, N.6
  • 38
    • 0034608948 scopus 로고    scopus 로고
    • Long-term prevention of renal insufficiency, excess matrix gene expression, and glomerular mesangial matrix expansion by treatment with monoclonal antitransform-ing growth factor- fj antibody in db/db diabetic mice
    • Ziyadeh FN, Hoffman BB, Han DC, Iglesiasde la Cruz MC, Hong SW, Isono M, Chen S, McGowan TA, Sharma K. Long-term prevention of renal insufficiency, excess matrix gene expression, and glomerular mesangial matrix expansion by treatment with monoclonal antitransform-ing growth factor- fj antibody in db/db diabetic mice. Proc Natl Acad Sci USA 97: 8015-8020, 2000.
    • (2000) Proc Natl Acad Sci USA , vol.97 , pp. 8015-8020
    • Ziyadeh, F.N.1    Hoffman, B.B.2    Han, D.C.3    la Cruz, M.C.I.4    Hong, S.W.5    Isono, M.6    Chen, S.7    McGowan, T.A.8    Sharma, K.9


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.