Organophosphorus pesticide degradation product in vitro metabolic stability and time-course uptake and elimination in rats following oral and intravenous dosing

Xenobiotica

Volumn 41, Issue 5, 2011, Pages 422-429

  Forsberg, N D ^a   Rodriguez Proteau, R ^a   Ma, L ^a   Morre J ^a   Christensen, J M ^a   Maier, C S ^a   Jenkins, J J ^a   Anderson, K A ^a  

^a OREGON STATE UNIVERSITY   (United States)

Author keywords

biomarker; biomonitoring; Dialkylphosphate; dimethylphosphate; exposure assessment; microsomes; pharmacokinetics

Indexed keywords

O,O DIMETHYLPHOSPHATE; O,O DIMETHYLTHIOPHOSPHATE; ORGANOPHOSPHATE PESTICIDE; TRAMADOL; UNCLASSIFIED DRUG;

ABSORPTION; ANIMAL CELL; ANIMAL EXPERIMENT; ARTICLE; BIOAVAILABILITY; BIOLOGICAL MONITORING; BLOOD ANALYSIS; HALF LIFE TIME; HUMAN; HUMAN CELL; IN VITRO STUDY; LIQUID CHROMATOGRAPHY; LIVER MICROSOME METABOLISM; MALE; MASS SPECTROMETRY; MAXIMUM PLASMA CONCENTRATION; NONHUMAN; RAT; TIME TO MAXIMUM PLASMA CONCENTRATION; URINALYSIS; URINARY EXCRETION;

ADMINISTRATION, ORAL; ANIMALS; ENVIRONMENTAL MONITORING; HUMANS; INJECTIONS, INTRAVENOUS; MALE; MASS SPECTROMETRY; ORGANOPHOSPHORUS COMPOUNDS; PESTICIDES; RATS; RATS, SPRAGUE-DAWLEY; TIME FACTORS;

RATTUS;

EID: 79954539273     PISSN: 00498254     EISSN: 13665928     Source Type: Journal    
DOI: 10.3109/00498254.2010.550656     Document Type: Article

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