Phosphoester modified poly(ethylenimine) as efficient and low cytotoxic genevectors

Science China Chemistry

Volumn 54, Issue 2, 2011, Pages 351-358

  Du, Jinzhi ^a   Tang, Lingyan ^b   Yuan, Youyong ^b   Wang, Jun ^b  

^a UNIVERSITY OF SCIENCE AND TECHNOLOGY OF CHINA   (China)

^b UNIVERSITY OF SCIENCE AND TECHNOLOGY OF CHINA   (China)

Author keywords

gene delivery; gene vector; PEI; phosphoester

Indexed keywords

CYTOTOXIC; GENE DELIVERY; GENE VECTOR; HEK-293; HELA CELL; IN-VITRO; MODIFICATION DEGREES; NONVIRAL GENE THERAPY; PEI; PHOSPHOESTER; PHYSIO-CHEMICAL; POLY(ETHYLENIMINE); POLYETHYLENIMINES; TRANSFECTION ABILITY; TRANSFECTION EFFICIENCY; ZETA POTENTIAL MEASUREMENTS;

BODY FLUIDS; CHEMICAL MODIFICATION; CYTOTOXICITY; EFFICIENCY; ETHYLENE; GENE TRANSFER; NUCLEAR MAGNETIC RESONANCE SPECTROSCOPY; NUCLEIC ACIDS; POLYETHYLENES; POLYMERS; ZETA POTENTIAL;

GENE THERAPY;

EID: 79954479671     PISSN: 16747291     EISSN: None     Source Type: Journal    
DOI: 10.1007/s11426-010-4210-x     Document Type: Article

References (36)

1. P.L. Felgner T.R. Gadek M. Holm R. Roman H.W. Chan M. Wenz J.P. Northrop G.M. Ringold M. Danielsen 1987 Lipofection: A highly efficient, lipid-mediated DNA-transfection procedure Proc Natl Acad Sci USA 84 21 7413 7417 10.1073/pnas.84.21.7413 1:CAS:528:DyaL1cXjtlSgug%3D%3D
2. P.L. Felgner G.M. Ringold 1989 Cationic liposome-mediated transfection Nature 337 6205 387 388 10.1038/337387a0 1:STN:280:DyaL1M%2Fpsleitw%3D%3D
3. X. Gao L. Huang 1991 A novel cationic liposome reagent for efficient transfection of mammalian cells Biochem Biophys Res Commun 179 1 280 285 10.1016/0006-291X(91)91366-K 1:CAS:528:DyaK3MXmt1Ggu74%3D
4. A. Baker M. Saltik H. Lehrmann I. Killisch V. Mautner G. Lamm G. Christofori M. Cotten 1997 Polyethylenimine (PEI) is a simple, inexpensive and effective reagent for condensing and linking plasmid DNA to adenovirus for gene delivery Gene Ther 4 8 773 782 10.1038/sj.gt.3300471 1:CAS:528: DyaK2sXltVaqtrc%3D (Pubitemid 27380159)
5. W.T. Godbey K.K. Wu A.G. Mikos 1999 Poly(ethylenimine) and its role in gene delivery J Controlled Release 60 2-3 149 160 10.1016/S0168-3659(99)00090-5 1:CAS:528:DyaK1MXks1Cqu7s%3D (Pubitemid 29335941)
6. U.K. Laemmli 1975 Characterization of DNA condensates induced by poly(ethylene oxide) and polylysine Proc Natl Acad Sci USA 72 11 4288 4292 10.1073/pnas.72.11.4288 1:CAS:528:DyaE28XislSmsQ%3D%3D
7. P. van de Wetering E.E. Moret N.M. Schuurmans-Nieuwenbroek M.J. van Steenbergen W.E. Hennink 1999 Structure-activity relationships of water-soluble cationic methacrylate/methacrylamide polymers for nonviral gene delivery Bioconjug Chem 10 4 589 597 10.1021/bc980148w (Pubitemid 29355237)
8. G. Borchard 2001 Chitosans for gene delivery Adv Drug Deliv Rev 52 2 145 150 10.1016/S0169-409X(01)00198-3 1:CAS:528:DC%2BD3MXosFKltbY%3D (Pubitemid 33079170)
9. J. Haensler F.C. Szoka Jr 1993 Polyamidoamine cascade polymers mediate efficient transfection of cells in culture Bioconjug Chem 4 5 372 379 10.1021/bc00023a012 1:CAS:528:DyaK3sXlslCqt7w%3D
10. A.U. Bielinska J.F. Kukowska-Latallo J.R. Baker Jr 1997 The interaction of plasmid DNA with polyamidoamine dendrimers: Mechanism of complex formation and analysis of alterations induced in nuclease sensitivity and transcriptional activity of the complexed DNA Biochim Biophys Acta 1353 2 180 190 1:CAS:528:DyaK2sXksFans7s%3D (Pubitemid 27360174)
11. B.H. Zinselmeyer S.P. Mackay A.G. Schatzlein I.F. Uchegbu 2002 The lower-generation polypropylenimine dendrimers are effective gene-transfer agents Pharm Res 19 7 960 967 10.1023/A:1016458104359 1:CAS:528:DC%2BD38Xltl2isLw%3D (Pubitemid 34808705)
12. O. Boussif F. Lezoualch M.A. Zanta M.D. Mergny D. Scherman B. Demeneix J.P. Behr 1995 A versatile vector for gene and oligonucleotide transfer into cells in culture and in vivo polyethylenimine Proc Natl Acad Sci USA 92 16 7297 7301 10.1073/pnas.92.16.7297 1:CAS:528:DyaK2MXntlKmt7s%3D
13. A. Zintchenko A. Philipp A. Dehshahri E. Wagner 2008 Simple modifications of branched PEI lead to highly efficient siRNA carriers with low toxicity Bioconjug Chem 19 7 1448 1455 10.1021/bc800065f 1:CAS:528:DC%2BD1cXnt1CmsLg%3D (Pubitemid 352032345)
14. A. Akinc M. Thomas A.M. Klibanov R. Langer 2005 Exploring polyethylenimine-mediated DNA transfection and the proton sponge hypothesis J Gene Med 7 5 657 663 10.1002/jgm.696 1:CAS:528:DC%2BD2MXltlGjsL8%3D (Pubitemid 40744532)
15. R. Kircheis L. Wightman E. Wagner 2001 Design and gene delivery activity of modified polyethylenimines Adv Drug Deliv Rev 53 3 341 358 10.1016/S0169-409X(01)00202-2 1:CAS:528:DC%2BD3MXovFyrtbk%3D (Pubitemid 34024914)
16. M.A. Mintzer E.E. Simanek 2009 Nonviral vectors for gene delivery Chem Rev 109 2 259 302 10.1021/cr800409e 1:CAS:528:DC%2BD1cXhsVOjsL3L
17. H. Petersen P.M. Fechner A.L. Martin K. Kunath S. Stolnik C.J. Roberts D. Fischer M.C. Davies T. Kissel 2002 Polyethylenimine-graft-poly (ethylene glycol) copolymers: Influence of copolymer block structure on DNA complexation and biological activities as gene delivery system Bioconjug Chem 13 4 845 854 10.1021/bc025529v 1:CAS:528:DC%2BD38Xks12rsrk%3D (Pubitemid 34801128)
18. H. Petersen K. Kunath T. Kissel A.L. Martin S. Stolnik C.J. Roberts M.C. Davies 2003 Star-shaped poly(ethylene glycol)-block-polyethylenimine copolymers enhance DNA condensation of low molecular weight polyethylenimines J Controlled Release 87 1-3 286 288
19. M.R. Park K.O. Han I.K. Han M.H. Cho J.W. Nah Y.J. Choi C.S. Cho 2005 Degradable polyethylenimine-alt-poly(ethylene glycol) copolymers as novel gene carriers J Controlled Release 105 3 367 380 10.1016/j.jconrel.2005.04.008 1:CAS:528:DC%2BD2MXlvVyrtbk%3D (Pubitemid 40942000)
20. A. Swami R.K. Kurupati A. Pathak Y. Singh P. Kumar K.C. Gupta 2007 A unique and highly efficient non-viral DNA/siRNA delivery system based on PEI-bisepoxide nanoparticles Biochem Bioph Res Co 362 4 835 841 10.1016/j.bbrc.2007.08.073 1:CAS:528:DC%2BD2sXhtVGisbfE (Pubitemid 47390649)
21. B. Liang M.L. He Z.P. Xiao Y. Li C.Y. Chan H.F. Kung X.T. Shuai Y. Peng 2008 Synthesis and characterization of folate-PEG-grafted-hyperbranched-PEI for tumor-targeted gene delivery Biochem Bioph Res Co 367 4 874 880 10.1016/j.bbrc.2008.01.024 1:CAS:528:DC%2BD1cXhsFylt7w%3D
22. M. Thomas A.M. Klibanov 2002 Enhancing polyethylenimine's delivery of plasmid DNA into mammalian cells Proc Natl Acad Sci USA 99 23 14640 14645 10.1073/pnas.192581499 1:CAS:528:DC%2BD38XovFOmsL4%3D (Pubitemid 35334537)
23. M.L. Forrest G.E. Meister J.T. Koerber D.W. Pack 2004 Partial acetylation of polyethylenimine enhances in vitro gene delivery Pharm Res 21 2 365 371 10.1023/B:PHAM.0000016251.42392.1e 1:CAS:528:DC%2BD2cXhtlWqsbY%3D (Pubitemid 38221984)
24. A.M. Doody J.N. Korley K.P. Dang P.N. Zawaneh D. Putnam 2006 Characterizing the structure/function parameter space of hydrocarbon-conjugated branched polyethylenimine for DNA delivery in vitro J Controlled Release 116 2 227 237 10.1016/j.jconrel.2006.07.019 1:CAS:528:DC%2BD28Xht12jtL3P (Pubitemid 44854283)
25. C.S. Xiao Y.C. Wang J.Z. Du X.S. Chen J. Wang 2006 Kinetics and mechanism of 2-ethoxy-2-oxo-1,3,2-dioxaphospholane polymerization initiated by stannous octoate Macromolecules 39 20 6825 6831 10.1021/ma0615396 1:CAS:528: DC%2BD28XptFagsbg%3D (Pubitemid 44625913)
26. J.M. Benns J.S. Choi R.I. Mahato J.S. Park S.W. Kim 2000 pH-sensitive cationic polymer gene delivery vehicle: N-Ac-poly(L-histidine)-graft-poly(L- lysine) comb shaped polymer Bioconjug Chem 11 5 637 645 10.1021/bc0000177 1:CAS:528:DC%2BD3cXmsV2jsbk%3D
27. N. Ashkenazi S.S. Zade Y. Segall Y. Karton M. Bendikov 2005 Selective site controlled nucleophilic attacks in 5-membered ring phosphoester esters: unusual C-O vs. common P-O bond cleavage Chem Commun 47 5879 5881 10.1039/b512117e (Pubitemid 43021903)
28. D.A. Wang A.S. Narang M. Kotb A.O. Gaber D.D. Miller S.W. Kim R.I. Mahato 2002 Novel branched poly(ethylenimine)-cholesterol water-soluble lipopolymers for gene delivery Biomacromolecules 3 6 1197 1207 10.1021/bm025563c 1:CAS:528:DC%2BD38XmslGns74%3D (Pubitemid 35423019)
29. S.C. De Smedt J. Demeester W.E. Hennink 2000 Cationic polymer based gene delivery systems Pharm Res 17 2 113 126 10.1023/A:1007548826495 (Pubitemid 30158358)
30. A. Kichler 2004 Gene transfer with modified polyethylenimines J Gene Med 6 S3 S10 10.1002/jgm.507 1:CAS:528:DC%2BD2cXislOmsrs%3D (Pubitemid 40228012)
31. Y.X. Sun W. Xiao S.X. Cheng X.Z. Zhang R.X. Zhuo 2008 Synthesis of (Dex-HMDI)-g-PEIs as effective and low cytotoxic nonviral gene vectors J Controlled Release 128 2 171 178 10.1016/j.jconrel.2008.03.004 1:CAS:528:DC%2BD1cXlvFKqtLw%3D
32. N. Wiradharma M. Khan Y.W. Tong S. Wang Y.Y. Yang 2008 Self-assembled cationic peptide nanoparticles capable of inducing efficient gene expression in vitro Adv Funct Mater 18 6 943 951 10.1002/adfm.200700884 1:CAS:528: DC%2BD1cXkslyhs7Y%3D (Pubitemid 351473708)
33. Y.T. Wen S.R. Pan X. Luo X. Zhang W. Zhang M. Feng 2009 A Biodegradable low molecular weight polyethylenimine derivative as low toxicity and efficient gene vector Bioconjug Chem 20 2 322 332 10.1021/bc800428y 1:CAS:528: DC%2BD1MXmvVWqtQ%3D%3D
34. C.K. Goldman L. Soroceanu N. Smith G.Y. Gillespie W. Shaw S. Burgess G. Bilbao D.T. Curiel 1997 In vitro and in vivo gene delivery mediated by a synthetic polycationic amino polymer Nat Biotechnol 15 5 462 466 10.1038/nbt0597-462 1:CAS:528:DyaK2sXivVyntrs%3D (Pubitemid 27197645)
35. T. Sato T. Ishii Y. Okahata 2001 In vitro gene delivery mediated by chitosan Effect of pH, serum, and molecular mass of chitosan on the transfection efficiency. Biomaterials 22 15 2075 2080 1:CAS:528:DC%2BD3MXlt1Kmt7s%3D
36. Y.C. Wang L.Y. Tang Y. Li J. Wang 2009 Thermoresponsive block copolymers of poly(ethylene glycol) and polyphosphoester: Thermo-induced self-assembly, biocompatibility, and hydrolytic degradation Biomacromolecules 10 66 73 10.1021/bm800808q 1:CAS:528:DC%2BD1cXhsVCrurbP