Evaluation of antimicrobial activity of new mastoparan derivatives using QSAR and computational mutagenesis

International Journal of Peptide Research and Therapeutics

Volumn 17, Issue 1, 2011, Pages 7-17

  Avram, Speranta ^a   Duda Seiman, Daniel ^b   Borcan, Florin ^b   Radu, Beatrice ^a   Duda Seiman, Corina ^c   Mihailescu, Dan ^a  

^a UNIVERSITY OF BUCHAREST   (Romania)

^b VICTOR BABES UNIVERSITY OF MEDICINE AND PHARMACY   (Romania)

^c WEST UNIVERSITY OF TIMISOARA   (Romania)

Author keywords

Antimicrobial peptides; Computational mutagenesis; QSAR

Indexed keywords

ASPARAGINYLISOLEUCYLTRYPTOPHYLLYSYLSERYLISOLEUCYLPHENYLALANYLGLUTAMYLSERYLVALYLLYSYLASPARAGINYLLEUCYLVALINE; ASPARAGINYLTRYPTOPHYLLYSYLLYSYLISOLEUCYLALANYLSERYLISOLEUCYLGLYCYLSERYLGLUTAMYLVALYLLEUCYLLYSYLALANYLLEUCYLLEUCYLALANYLLEUCINE; ISOLEUCYLASPARAGINYLPHENYLALANYLLEUCYLLYSYLLEUCYLGLYCYLLYSYLLYSYLISOLEUCYLLEUCYLGLYCYLALANYLLEUCINE; ISOLEUCYLASPARAGINYLSERYLLEUCYLLYSYLLEUCYLGLYCYLLYSYLLYSYLISOLEUCYLLEUCYLGLYCYLALANYLLEUCINE; ISOLEUCYLASPARAGINYLTRYPTOPHYLLEUCYLARGINYLLEUCYLGLYCYLARGINYLARGINYLISOLEUCYLLEUCYLGLYCYLALANYLLEUCINE; ISOLEUCYLASPARAGINYLTRYPTOPHYLLEUCYLLYSYLLEUCYLGLCYLLYSYLLYSYLISOLEUCYLLEUCYLGLYCYLALANYLLEUCINE; ISOLEUCYLASPARAGINYLTRYPTOPHYLLEUCYLLYSYLLEUCYLGLYCYLLYSYLLYSYLISOLUCYLLEUCYLGLYCYLALANYLISOLEUCINE; ISOLEUCYLASPARAGINYLTRYPTOPHYLLEUCYLLYSYLLEUCYLGLYCYLLYSYLLYSYLLEUCYLLEUCYLSERYLALANYLLEUCINE; ISOLEUCYLASPARAGINYLTRYPTOPHYLLEUCYLLYSYLLEUCYLGLYCYLLYSYLLYSYLMETHIONYLMETHIONYSERYLALANYLISOLEUCINE; ISOLEUCYLASPARAGINYLTRYPTOPHYLLEUCYLLYSYLLEUCYLGLYCYLLYSYLLYSYLMETHIONYLMETHIONYSERYLALANYLLEUCINE; ISOLEUCYLASPARAGINYLTRYPTOPHYLLYSYLLYSYLISOLEUCYLALANYLSERYLISOLEUCYLGLYCYLSERYLGLUTAMYLVALYLLEUCYLLYSYLALANYLLEUCYLLEUCYLALANYLISOLEUCINE; ISOLEUCYLASPARAGINYLTRYPTOPHYLLYSYLLYSYLISOLEUCYLALANYLSERYLISOLEUCYLGLYCYLSERYLGLUTAMYLVALYLLEUCYLLYSYLALANYLLEUCYLLEUCYLALANYLLEUCINE; ISOLEUCYLASPARAGINYLTRYPTOPHYLLYSYLLYSYLISOLEUCYLPHENYLALANYLGLUTAMINYLLYSYLVALYLLYSYLASPARAGINYLLEUCYLVALINE; ISOLEUCYLASPARAGINYLTRYPTOPHYLLYSYLLYSYLISOLEUCYLPHENYLALANYLGLUTAMYLLYSYLVALYLLYSYLASPARAGINYLLEUCYLVALINE; ISOLEUCYLASPARAGINYLTRYPTOPHYLLYSYLLYSYLISOLEUCYLPHENYLALANYLGLUTAMYLLYSYLVALYLLYSYLASPARTYLLEUCYLVALINE; ISOLEUCYLASPARAGINYLTRYPTOPHYLLYSYLLYSYLISOLEUCYLPHENYLALANYLGLUTAMYLLYSYLVALYLSERYLASPARAGINYLLEUCYLVALINE; ISOLEUCYLASPARAGINYLTRYPTOPHYLLYSYLLYSYLISOLEUCYLPHENYLALANYLGLUTAMYLSERYLVALYLLYSYLASPARAGINYLLEUCYLVALINE; ISOLEUCYLASPARAGINYLTRYPTOPHYLLYSYLLYSYLLEUCYLGLYCYLLYSYLLYSYLISOLEUCYLLEUCYLGLYCYLALANYLLEUCINE; ISOLEUCYLASPARAGINYLTRYPTOPHYLLYSYLSERYLISOLEUCYLPHENYLALANYLGLUTAMYLSERYLVALYLLYSYLASPARAGINYLLEUCYLVALINE; ISOLEUCYLASPARAGINYLTRYPTOPHYLSERYLLYSYLISOLEUCYLPHENYLALANYLGLUTAMYLLYSYLVALYLLYSYLASPARAGINYLLEUCYLVALINE; ISOLEUCYLASPARAGINYLTRYPTOPHYLSERYLSERYLISOLEUCYLPHENYLALANYLGLUTAMYLLYSYLVALYLLYSYLASPARAGINYLLEUCYLVALINE; ISOLEUCYLASPARAGINYLTRYPTOPHYLSERYLSERYLISOLEUCYLPHENYLALANYLGLUTAMYLSERYLVALYLLYSYLASPARAGINYLLEUCYLVALINE; ISOLEUCYLASPARAGINYLTRYPTOPHYLSERYLSERYLISOLEUCYLPHENYLALANYLGLUTAMYLSERYLVALYLSERYLASPARAGINYLLEUCYLVALINE; ISOLEUCYLASPARTYLTRYPTOPHYLLYSYLLYSYLISOLEUCYLPHENYLALANYLGLUTAMYLLYSYLVALYLLYSYLASPARAGINYLLEUCYLVALINE; ISOLEUCYLASPARTYLTRYPTOPHYLLYSYLLYSYLISOLEUCYLPHENYLALANYLGLUTAMYLLYSYLVALYLLYSYLASPARTYLLEUCYLVALINE; MASTOPARAN; POLYPEPTIDE ANTIBIOTIC AGENT; SERYLASPARAGINYLTRYPTOPHYLLEUCYLLYSYLLEUCYLGLYCYLLYSYLLYSYLLEUCYLLEUCYLALANYLLEUCINE; TRYPTOPHYLLYSYLLYSYLISOLEUCYLALANYLSERYLISOLEUCYLGLYCYLSERYLGLUTAMYLVALYLLEUCYLLYSYLALANYLLEUCYLLEUCYLALANYLLEUCINE; UNCLASSIFIED DRUG; UNINDEXED DRUG;

ANTIMICROBIAL ACTIVITY; ARTICLE; BACILLUS SUBTILIS; COMPUTATIONAL MUTAGENESIS; DRUG STRUCTURE; MINIMUM INHIBITORY CONCENTRATION; MUTAGENESIS; NONHUMAN; QUANTITATIVE STRUCTURE ACTIVITY RELATION; STATISTICAL MODEL; STRUCTURE ANALYSIS;

BACILLUS SUBTILIS; CORYNEBACTERINEAE; FUNGI;

EID: 79954437730     PISSN: 15733149     EISSN: 15733904     Source Type: Journal    
DOI: 10.1007/s10989-010-9235-7     Document Type: Article

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