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Volumn 36, Issue 5, 2011, Pages 856-862

Upregulation of inflammatory mediators in a model of chronic pain after spinal cord injury

Author keywords

Chemokines; Cytokines; Inflammation; Matrix metalloproteinases; Neuropathic pain; Spinal cord injury

Indexed keywords

ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ARTICLE; CHRONIC PAIN; CONTROLLED STUDY; GENE; GENE EXPRESSION; HYPERALGESIA; INTERLEUKIN 1BETA GENE; LATENT PERIOD; LOCOMOTION; MALE; MATRIX METALLOPROTEINASE 9 GENE; MONOCYTE CHEMOTACTIC PROTEIN 1 GENE; NERVOUS SYSTEM INFLAMMATION; NEUROPATHIC PAIN; NONHUMAN; NUCLEOTIDE SEQUENCE; PARAPLEGIA; PRIORITY JOURNAL; RAT; SPINAL CORD INJURY; THERMAL HYPERALGESIA; TISSUE INHIBITOR OF METALLOPROTEINASE 1 GENE; TUMOR NECROSIS FACTOR ALPHA GENE; UPREGULATION;

EID: 79954430475     PISSN: 03643190     EISSN: None     Source Type: Journal    
DOI: 10.1007/s11064-011-0414-5     Document Type: Article
Times cited : (54)

References (42)
  • 1
    • 0035893632 scopus 로고    scopus 로고
    • Epidemiology, demographics, and pathophysiology of acute spinal cord injury
    • LHS Sekhon MG Fehlings 2001 Epidemiology, demographics, and pathophysiology of acute spinal cord injury Spine 26 24S S2 S12 11805601 10.1097/00007632-200112151-00002 1:STN:280:DC%2BD38%2FotVaqsw%3D%3D (Pubitemid 34019773)
    • (2001) Spine , vol.26 , Issue.24 SUPPL.
    • Sekhon, L.H.S.1    Fehlings, M.G.2
  • 2
    • 50349093251 scopus 로고    scopus 로고
    • Locomotor dysfunction and pain: The scylla and charybdis of fiber sprouting after spinal cord injury
    • 18415034 10.1007/s12035-008-8016-1 1:CAS:528:DC%2BD1cXmsVOjs7w%3D
    • R Deumens EA Joosten SG Waxman BC Hains 2008 Locomotor dysfunction and pain: the scylla and charybdis of fiber sprouting after spinal cord injury Mol Neurobiol 37 52 63 18415034 10.1007/s12035-008-8016-1 1:CAS:528: DC%2BD1cXmsVOjs7w%3D
    • (2008) Mol Neurobiol , vol.37 , pp. 52-63
    • Deumens, R.1    Joosten, E.A.2    Waxman, S.G.3    Hains, B.C.4
  • 4
    • 0034973293 scopus 로고    scopus 로고
    • Pain and dysesthesia in patients with spinal cord injury: A postal survey
    • DOI 10.1038/sj.sc.3101161
    • NB Finnerup IL Johannesen SH Sindrup FW Bach TS Jensen 2001 Pain and dysesthesia in patients with spinal cord injury: a postal survey Spinal Cord 39 256 262 11438841 10.1038/sj.sc.3101161 1:STN:280:DC%2BD3MznvFOjsA%3D%3D (Pubitemid 32566072)
    • (2001) Spinal Cord , vol.39 , Issue.5 , pp. 256-262
    • Finnerup, N.B.1    Johannesen, I.L.2    Sindrup, S.H.3    Bach, F.W.4    Jensen, T.S.5
  • 5
    • 49049093990 scopus 로고    scopus 로고
    • Propentofylline attenuates allodynia, glial activation and modulates GABAergic tone after spinal cord injury in the rat
    • 18353556 10.1016/j.pain.2008.01.021 1:CAS:528:DC%2BD1cXhtVSisLbN
    • YS Gwak ED Crown GC Unabia CE Hulsebosch 2008 Propentofylline attenuates allodynia, glial activation and modulates GABAergic tone after spinal cord injury in the rat Pain 138 410 422 18353556 10.1016/j.pain.2008.01.021 1:CAS:528:DC%2BD1cXhtVSisLbN
    • (2008) Pain , vol.138 , pp. 410-422
    • Gwak, Y.S.1    Crown, E.D.2    Unabia, G.C.3    Hulsebosch, C.E.4
  • 6
    • 7244242234 scopus 로고    scopus 로고
    • Targeting recovery: Priorities of the spinal cord-injured population
    • DOI 10.1089/neu.2004.21.1371
    • KD Anderson 2004 Targeting recovery: priorities of the spinal cord-injured population J Neurotrauma 21 1371 1383 15672628 10.1089/neu.2004.21. 1371 (Pubitemid 39435314)
    • (2004) Journal of Neurotrauma , vol.21 , Issue.10 , pp. 1371-1383
    • Anderson, K.D.1
  • 7
    • 0033526651 scopus 로고    scopus 로고
    • Neuropathic pain: Aetiology, symptoms, mechanisms, and management
    • DOI 10.1016/S0140-6736(99)01307-0
    • CJ Woolf RJ Mannion 1999 Neuropathic pain: aetiology, symptoms, mechanisms, and management Lancet 353 1959 1964 10371588 10.1016/S0140-6736(99) 01307-0 1:STN:280:DyaK1M3psl2qug%3D%3D (Pubitemid 29255720)
    • (1999) Lancet , vol.353 , Issue.9168 , pp. 1959-1964
    • Woolf, C.J.1    Mannion, R.J.2
  • 9
    • 57749200564 scopus 로고    scopus 로고
    • Pathological and protective roles of glia in chronic pain
    • 19096368 10.1038/nrn2533 1:CAS:528:DC%2BD1MXpt1ek
    • ED Milligan LR Watkins 2009 Pathological and protective roles of glia in chronic pain Nat Rev Neurosci 10 23 36 19096368 10.1038/nrn2533 1:CAS:528:DC%2BD1MXpt1ek
    • (2009) Nat Rev Neurosci , vol.10 , pp. 23-36
    • Milligan, E.D.1    Watkins, L.R.2
  • 10
    • 33745153343 scopus 로고    scopus 로고
    • Immune and inflammatory mechanisms in neuropathic pain
    • DOI 10.1016/j.brainresrev.2005.11.004, PII S0165017305001700
    • G Moalem DJ Tracey 2006 Immune and inflammatory mechanisms in neuropathic pain Brain Res Rev 51 240 264 16388853 10.1016/j.brainresrev.2005.11.004 1:CAS:528:DC%2BD28XlvFGgu7Y%3D (Pubitemid 43902971)
    • (2006) Brain Research Reviews , vol.51 , Issue.2 , pp. 240-264
    • Moalem, G.1    Tracey, D.J.2
  • 11
    • 54049134709 scopus 로고    scopus 로고
    • Gliopathy ensures persistent inflammation and chronic pain after spinal cord injury
    • 18708053 10.1016/j.expneurol.2008.07.016 1:CAS:528:DC%2BD1cXht12ns7zJ
    • CE Hulsebosch 2008 Gliopathy ensures persistent inflammation and chronic pain after spinal cord injury Exp Neurol 214 6 9 18708053 10.1016/j.expneurol. 2008.07.016 1:CAS:528:DC%2BD1cXht12ns7zJ
    • (2008) Exp Neurol , vol.214 , pp. 6-9
    • Hulsebosch, C.E.1
  • 12
    • 33846840997 scopus 로고    scopus 로고
    • Subacute human spinal cord contusion: Few lymphocytes and many macrophages
    • DOI 10.1038/sj.sc.3101910, PII 3101910
    • HT Chang 2007 Subacute human spinal cord contusion: few lymphocytes and many macrophages Spinal Cord 45 174 182 16505827 10.1038/sj.sc.3101910 1:STN:280:DC%2BD2s%2FmtleqsA%3D%3D (Pubitemid 46204266)
    • (2007) Spinal Cord , vol.45 , Issue.2 , pp. 174-182
    • Chang, H.T.1
  • 13
    • 33847337984 scopus 로고    scopus 로고
    • 2 contributes to pain after spinal cord injury
    • DOI 10.1523/JNEUROSCI.0138-07.2007
    • P Zhao SG Waxman BC Hains 2007 Extracellular signal-regulated kinase-regulated microglia-neuron signaling by prostaglandin E2 contributes to pain after spinal cord injury J Neurosci 27 2357 2368 17329433 10.1523/JNEUROSCI.0138-07.2007 1:CAS:528:DC%2BD2sXjsVymsLo%3D (Pubitemid 46340975)
    • (2007) Journal of Neuroscience , vol.27 , Issue.9 , pp. 2357-2368
    • Zhao, P.1    Waxman, S.G.2    Hains, B.C.3
  • 14
    • 34548295757 scopus 로고    scopus 로고
    • Distinct types of microglial activation in white and grey matter of rat lumbosacral cord after mid-thoracic spinal transection
    • DOI 10.1097/nen.0b013e3181256b32, PII 0000507220070800000004
    • SM McKay DJ Brooks P Hu EM McLachlan 2007 Distinct types of microglial activation in white and grey matter of rat lumbosacral cord after mid-thoracic spinal transection J Neuropathol Exp Neurol 66 698 710 17882014 10.1097/nen.0b013e3181256b32 (Pubitemid 47344249)
    • (2007) Journal of Neuropathology and Experimental Neurology , vol.66 , Issue.8 , pp. 698-710
    • McKay, S.M.1    Brooks, D.J.2    Hu, P.3    McLachlan, E.M.4
  • 15
    • 34548096949 scopus 로고    scopus 로고
    • Modulation of thalamic nociceptive processing after spinal cord injury through remote activation of thalamic microglia by cysteine-cysteine chemokine ligand 21
    • DOI 10.1523/JNEUROSCI.2209-07.2007
    • P Zhao SG Waxman BC Hains 2007 Modulation of thalamic nociceptive processing after spinal cord injury through remote activation of thalamic microglia by cysteine cysteine chemokine ligand 21 J Neurosci 27 8893 8902 17699671 10.1523/JNEUROSCI.2209-07.2007 1:CAS:528:DC%2BD2sXhtVegt7bJ (Pubitemid 47292772)
    • (2007) Journal of Neuroscience , vol.27 , Issue.33 , pp. 8893-8902
    • Zhao, P.1    Waxman, S.G.2    Hains, B.C.3
  • 16
    • 34249795149 scopus 로고    scopus 로고
    • Glial-cytokine-neuronal interactions underlying the mechanisms of persistent pain
    • DOI 10.1523/JNEUROSCI.0176-07.2007
    • W Guo H Wang M Watanabe K Shimizu S Zou SC LaGraize, et al. 2007 Glial-cytokine-neuronal interactions underlying the mechanisms of persistent pain J Neurosci 27 6006 6018 17537972 10.1523/JNEUROSCI.0176-07.2007 1:CAS:528:DC%2BD2sXmsVWkt7k%3D (Pubitemid 46849761)
    • (2007) Journal of Neuroscience , vol.27 , Issue.22 , pp. 6006-6018
    • Guo, W.1    Wang, H.2    Watanabe, M.3    Shimizu, K.4    Zou, S.5    LaGraize, S.C.6    Wei, F.7    Dubner, R.8    Ren, K.9
  • 17
    • 49349110301 scopus 로고    scopus 로고
    • Modulation of microglia can attenuate neuropathic pain symptoms and enhance morphine effectiveness
    • 18622054 1:CAS:528:DC%2BD1cXhtF2rt7rF
    • J Mika 2008 Modulation of microglia can attenuate neuropathic pain symptoms and enhance morphine effectiveness Pharmacol Rep 60 297 307 18622054 1:CAS:528:DC%2BD1cXhtF2rt7rF
    • (2008) Pharmacol Rep , vol.60 , pp. 297-307
    • Mika, J.1
  • 18
    • 34249667153 scopus 로고    scopus 로고
    • Cytokine regulation of MMP-9 in peripheral glia: Implications for pathological processes and pain in injured nerve
    • DOI 10.1016/j.bbi.2006.10.015, PII S0889159106003515, Neuropathic Pain, Glia and Cytokines
    • S Chattopadhyay RR Myers J Janes V Shubayev 2007 Cytokine regulation of MMP-9 in peripheral glia: implications for pathological processes and pain in injured nerve Brain, Behavior, Immun 21 561 568 10.1016/j.bbi.2006.10.015 1:CAS:528:DC%2BD2sXmtVOmtbg%3D (Pubitemid 46829772)
    • (2007) Brain, Behavior, and Immunity , vol.21 , Issue.5 , pp. 561-568
    • Chattopadhyay, S.1    Myers, R.R.2    Janes, J.3    Shubayev, V.4
  • 19
    • 68049098298 scopus 로고    scopus 로고
    • Neuroinflammation in spinal cord injury: Therapeutic targets for neuroprotection and regeneration
    • 19660652 10.1016/S0079-6123(09)17508-8 1:CAS:528:DC%2BD1MXhsVeht7vN
    • JK Alexander PG Popovich 2009 Neuroinflammation in spinal cord injury: therapeutic targets for neuroprotection and regeneration Prog Brain Res 175 125 137 19660652 10.1016/S0079-6123(09)17508-8 1:CAS:528:DC%2BD1MXhsVeht7vN
    • (2009) Prog Brain Res , vol.175 , pp. 125-137
    • Alexander, J.K.1    Popovich, P.G.2
  • 20
    • 69449092398 scopus 로고    scopus 로고
    • Early microglial inhibition preemptively mitigates chronic pain development after experimental spinal cord injury
    • 19533525 10.1682/JRRD.2008.03.0048
    • AM Tan P Zhao SG Waxman BC Hains 2009 Early microglial inhibition preemptively mitigates chronic pain development after experimental spinal cord injury J Rehabil Res Dev 46 123 133 19533525 10.1682/JRRD.2008.03.0048
    • (2009) J Rehabil Res Dev , vol.46 , pp. 123-133
    • Tan, A.M.1    Zhao, P.2    Waxman, S.G.3    Hains, B.C.4
  • 21
    • 33750480849 scopus 로고    scopus 로고
    • Functional magnetic resonance imaging in rodents: Methodology and application to spinal cord injury
    • DOI 10.1002/jnr.21030
    • J Ramu KH Bockhorst KV Mogatadakala PA Narayana 2006 Functional magnetic resonance imaging in rodents: methodology and application to spinal cord injury J Neurosci Res 84 1235 1244 16941500 10.1002/jnr.21030 1:CAS:528: DC%2BD28XhtF2rs7vN (Pubitemid 44654447)
    • (2006) Journal of Neuroscience Research , vol.84 , Issue.6 , pp. 1235-1244
    • Ramu, J.1    Bockhorst, K.H.2    Mogatadakala, K.V.3    Narayana, P.A.4
  • 22
    • 24044458211 scopus 로고    scopus 로고
    • A new device for experimental modeling of central nervous system injuries
    • DOI 10.1177/1545968305278635
    • M Bilgen 2005 A new device for experimental modeling of central nervous system injuries Neurorehabil Neural Repair 19 219 226 16093412 10.1177/1545968305278635 (Pubitemid 41216297)
    • (2005) Neurorehabilitation and Neural Repair , vol.19 , Issue.3 , pp. 219-226
    • Bilgen, M.1
  • 23
    • 0028919411 scopus 로고
    • A sensitive and reliable locomotor rating scale for open field testing in rats
    • 7783230 10.1089/neu.1995.12.1 1:STN:280:DyaK2Mzgt1GhtQ%3D%3D
    • DM Basso MS Beattie JC Bresnahan 1995 A sensitive and reliable locomotor rating scale for open field testing in rats J Neurotrauma 12 1 21 7783230 10.1089/neu.1995.12.1 1:STN:280:DyaK2Mzgt1GhtQ%3D%3D
    • (1995) J Neurotrauma , vol.12 , pp. 1-21
    • Basso, D.M.1    Beattie, M.S.2    Bresnahan, J.C.3
  • 24
    • 0036581160 scopus 로고    scopus 로고
    • Relative expression software tool (REST) for group-wise comparison and statistical analysis of relative expression results in real-time PCR
    • 11972351 10.1093/nar/30.9.e36
    • MW Pfaffl GW Horgan L Dempfle 2002 Relative expression software tool (REST) for group-wise comparison and statistical analysis of relative expression results in real-time PCR Nucleic Acids Res 30 e36 11972351 10.1093/nar/30.9.e36
    • (2002) Nucleic Acids Res , vol.30
    • Pfaffl, M.W.1    Horgan, G.W.2    Dempfle, L.3
  • 25
    • 75149173405 scopus 로고    scopus 로고
    • Intensity of pain and biochemical changes in blood plasma in spinal cord trauma
    • 19546874 10.1038/sc.2009.71 1:STN:280:DC%2BC3c%2FgvFWhtQ%3D%3D
    • A Yamamotova T Sramkova R Rokyta 2010 Intensity of pain and biochemical changes in blood plasma in spinal cord trauma Spinal Cord 48 21 26 19546874 10.1038/sc.2009.71 1:STN:280:DC%2BC3c%2FgvFWhtQ%3D%3D
    • (2010) Spinal Cord , vol.48 , pp. 21-26
    • Yamamotova, A.1    Sramkova, T.2    Rokyta, R.3
  • 26
    • 2442436386 scopus 로고    scopus 로고
    • Locomotor recovery and mechanical hyperalgesia following spinal cord injury depend on age at time of injury in rat
    • DOI 10.1016/j.neulet.2004.03.019, PII S0304394004003131
    • YS Gwak BC Hains KM Johnson CE Hulsebosch 2004 Locomotor recovery and mechanical hyperalgesia following spinal cord injury depend on age at time of injury in rat Neurosci Lett 362 232 235 15158021 10.1016/j.neulet.2004.03.019 1:CAS:528:DC%2BD2cXkt1Sls7Y%3D (Pubitemid 38648948)
    • (2004) Neuroscience Letters , vol.362 , Issue.3 , pp. 232-235
    • Gwak, Y.S.1    Hains, B.C.2    Johnson, K.M.3    Hulsebosch, C.E.4
  • 27
    • 47349092661 scopus 로고    scopus 로고
    • Remote activation of microglia and pro-inflammatory cytokines predict the onset and severity of below-level neuropathic pain after spinal cord injury in rats
    • 18511041 10.1016/j.expneurol.2008.04.009 1:CAS:528:DC%2BD1cXptVCjtrY%3D
    • MR Detloff LC Fisher V McGaughy EE Longbrake PG Popovich DM Basso 2008 Remote activation of microglia and pro-inflammatory cytokines predict the onset and severity of below-level neuropathic pain after spinal cord injury in rats Exp Neurol 212 337 347 18511041 10.1016/j.expneurol.2008.04.009 1:CAS:528:DC%2BD1cXptVCjtrY%3D
    • (2008) Exp Neurol , vol.212 , pp. 337-347
    • Detloff, M.R.1    Fisher, L.C.2    McGaughy, V.3    Longbrake, E.E.4    Popovich, P.G.5    Basso, D.M.6
  • 28
    • 35448945675 scopus 로고    scopus 로고
    • Mice overexpressing chemokine ligand 2 (CCL2) in astrocytes display enhanced nociceptive responses
    • DOI 10.1016/j.neuroscience.2007.08.014, PII S0306452207010172
    • J Menetski S Mistry M Lu JS Mudgett RM Ransohoff JA Demartino, et al. 2007 Mice overexpressing chemokine ligand 2 (CCL2) in astrocytes display enhanced nociceptive responses Neuroscience 149 706 714 17870246 10.1016/j.neuroscience.2007.08.014 1:CAS:528:DC%2BD2sXht1ahu7bP (Pubitemid 47633032)
    • (2007) Neuroscience , vol.149 , Issue.3 , pp. 706-714
    • Menetski, J.1    Mistry, S.2    Lu, M.3    Mudgett, J.S.4    Ransohoff, R.M.5    DeMartino, J.A.6    MacIntyre, D.E.7    Abbadie, C.8
  • 29
    • 36048991728 scopus 로고    scopus 로고
    • Expression of CCR2 in both resident and bone marrow-derived microglia plays a critical role in neuropathic pain
    • DOI 10.1523/JNEUROSCI.3016-07.2007
    • J Zhang XQ Shi S Echeverry JS Mogil Y De Koninck S Rivest 2007 Expression of CCR2 in both resident and bone marrow-derived microglia plays a critical role in neuropathic pain J Neurosci 27 12396 12406 17989304 10.1523/JNEUROSCI. 3016-07.2007 1:CAS:528:DC%2BD2sXhtlartLbI (Pubitemid 350085465)
    • (2007) Journal of Neuroscience , vol.27 , Issue.45 , pp. 12396-12406
    • Zhang, J.1    Xiang, Q.S.2    Echeverry, S.3    Mogil, J.S.4    De Koninck, Y.5    Rivest, S.6
  • 30
    • 65249114367 scopus 로고    scopus 로고
    • JNK-induced MCP-1 production in spinal cord astrocytes contributes to central sensitization and neuropathic pain
    • 19339605 10.1523/JNEUROSCI.3623-08.2009 1:CAS:528:DC%2BD1MXktlaktLw%3D
    • YJ Gao L Zhang OA Samad MR Suter K Yasuhiko ZZ Xu, et al. 2009 JNK-induced MCP-1 production in spinal cord astrocytes contributes to central sensitization and neuropathic pain J Neurosci 29 4096 4108 19339605 10.1523/JNEUROSCI.3623-08.2009 1:CAS:528:DC%2BD1MXktlaktLw%3D
    • (2009) J Neurosci , vol.29 , pp. 4096-4108
    • Gao, Y.J.1    Zhang, L.2    Samad, O.A.3    Suter, M.R.4    Yasuhiko, K.5    Xu, Z.Z.6
  • 31
    • 25144515027 scopus 로고    scopus 로고
    • Monocyte chemoattractant protein-1 level in serum of patients with acute spinal cord injury
    • SQ Liu YG Ma H Peng L Fan 2005 Monocyte chemoattractant protein-1 level in serum of patients with acute spinal cord injury Chin J Traumatol 8 216 219 16042867 1:CAS:528:DC%2BD2MXpvVWqt7Y%3D (Pubitemid 41335109)
    • (2005) Chinese Journal of Traumatology - English Edition , vol.8 , Issue.4 , pp. 216-219
    • Liu, S.-Q.1    Ma, Y.-G.2    Peng, H.3    Fan, L.4
  • 32
    • 39049085666 scopus 로고    scopus 로고
    • Delayed functional expression of neuronal chemokine receptors following focal nerve demyelination in the rat: A mechanism for the development of chronic sensitization of peripheral nociceptors
    • DOI 10.1186/1744-8069-3-38
    • S Bhangoo D Ren RJ Miller KJ Henry J Lineswala C Hamdouchi, et al. 2007 Delayed functional expression of neuronal chemokine receptors following focal nerve demyelination in the rat: a mechanism for the development of chronic sensitization of peripheral nociceptors Mol Pain 3 38 18076762 10.1186/1744-8069-3-38 (Pubitemid 351234176)
    • (2007) Molecular Pain , vol.3 , pp. 38
    • Bhangoo, S.1    Ren, D.2    Miller, R.J.3    Henry, K.J.4    Lineswala, J.5    Hamdouchi, C.6    Li, B.7    Monahan, P.E.8    Chan, D.M.9    Ripsch, M.S.10    White, F.A.11
  • 33
    • 43649096224 scopus 로고    scopus 로고
    • Force-dependent development of neuropathic central pain and time-related CCL2/CCR2 expression after graded spinal cord contusion injuries of the rat
    • DOI 10.1089/neu.2007.0431
    • F Knerlich-Lukoschus M Juraschek U Blomer R Lucius HM Mehdorn J Held-Feindt 2008 Force-dependent development of neuropathic central pain and time-related CCL2/CCR2 expression after graded spinal cord contusion injuries of the rat J Neurotrauma 25 427 448 18338959 10.1089/neu.2007.0431 (Pubitemid 351685487)
    • (2008) Journal of Neurotrauma , vol.25 , Issue.5 , pp. 427-448
    • Knerlich-Lukoschus, F.1    Juraschek, M.2    Blomer, U.3    Lucius, R.4    Mehdorn, H.M.5    Held-Feindt, J.6
  • 34
    • 69749104787 scopus 로고    scopus 로고
    • Chemokine signaling and the management of neuropathic pain
    • 19720751 10.1124/mi.9.4.7 1:CAS:528:DC%2BD1MXht1WhtrjK
    • FA White P Feldman RJ Miller 2009 Chemokine signaling and the management of neuropathic pain Mol Interv 9 188 195 19720751 10.1124/mi.9.4.7 1:CAS:528:DC%2BD1MXht1WhtrjK
    • (2009) Mol Interv , vol.9 , pp. 188-195
    • White, F.A.1    Feldman, P.2    Miller, R.J.3
  • 35
    • 67649394340 scopus 로고    scopus 로고
    • Matrix metalloprotease regulation of neuropathic pain
    • 19523695 10.1016/j.tips.2009.04.002 1:CAS:528:DC%2BD1MXotFClsr8%3D
    • R-R Ji Z-Z Xu X Wang EH Lo 2009 Matrix metalloprotease regulation of neuropathic pain Trends Pharmacol Sci 30 336 340 19523695 10.1016/j.tips.2009. 04.002 1:CAS:528:DC%2BD1MXotFClsr8%3D
    • (2009) Trends Pharmacol Sci , vol.30 , pp. 336-340
    • Ji, R.-R.1    Xu, Z.-Z.2    Wang, X.3    Lo, E.H.4
  • 37
    • 0141497935 scopus 로고    scopus 로고
    • Differential temporal expression of matrix metalloproteinases after spinal cord injury: Relationship to revascularization and wound healing
    • 12956462 10.3171/jns.2003.99.1.0188 1:CAS:528:DC%2BD3sXnsVSnu74%3D
    • S Goussev JY Hsu Y Lin T Tjoa N Maida Z Werb, et al. 2003 Differential temporal expression of matrix metalloproteinases after spinal cord injury: relationship to revascularization and wound healing J Neurosurg 99 188 197 12956462 10.3171/jns.2003.99.1.0188 1:CAS:528:DC%2BD3sXnsVSnu74%3D
    • (2003) J Neurosurg , vol.99 , pp. 188-197
    • Goussev, S.1    Hsu, J.Y.2    Lin, Y.3    Tjoa, T.4    Maida, N.5    Werb, Z.6
  • 38
    • 75449117953 scopus 로고    scopus 로고
    • Neuroprotective effects of over-expressing tissue inhibitor of metalloproteinase TIMP-1
    • 19469687 10.1089/neu.2009.0959
    • E Tejima S Guo Y Murata K Arai J Lok K van Leyen, et al. 2009 Neuroprotective effects of over-expressing tissue inhibitor of metalloproteinase TIMP-1 J Neurotrauma 26 1935 1941 19469687 10.1089/neu.2009.0959
    • (2009) J Neurotrauma , vol.26 , pp. 1935-1941
    • Tejima, E.1    Guo, S.2    Murata, Y.3    Arai, K.4    Lok, J.5    Van Leyen, K.6
  • 39
    • 48849107531 scopus 로고    scopus 로고
    • Tissue inhibitors of metalloproteinases in cell signaling: Metalloproteinase-independent biological activities
    • 18612141 10.1126/scisignal.127re6
    • WG Stetler-Stevenson 2008 Tissue inhibitors of metalloproteinases in cell signaling: metalloproteinase-independent biological activities Sci Signal 1 re6 18612141 10.1126/scisignal.127re6
    • (2008) Sci Signal , vol.1 , pp. 6
    • Stetler-Stevenson, W.G.1
  • 40
    • 33646541350 scopus 로고    scopus 로고
    • Novel functions of TIMPs in cell signaling
    • DOI 10.1007/s10555-006-7893-x, Metalloproteinases and Cancer
    • R Chirco XW Liu KK Jung HR Kim 2006 Novel functions of TIMPs in cell signaling Cancer Metastasis Rev 25 99 113 16680576 10.1007/s10555-006-7893-x 1:CAS:528:DC%2BD28Xktlaksro%3D (Pubitemid 43723986)
    • (2006) Cancer and Metastasis Reviews , vol.25 , Issue.1 , pp. 99-113
    • Chirco, R.1    Liu, X.-W.2    Jung, K.-K.3    Kim, H.-R.C.4
  • 41
    • 35448987983 scopus 로고    scopus 로고
    • Clinical Correlates of Elevated Serum Concentrations of Cytokines and Autoantibodies in Patients With Spinal Cord Injury
    • DOI 10.1016/j.apmr.2007.08.004, PII S0003999307013421
    • AL Davies KC Hayes GA Dekaban 2007 Clinical correlates of elevated serum concentrations of cytokines and autoantibodies in patients with spinal cord injury Arch Phys Med Rehabil 88 1384 1393 17964877 10.1016/j.apmr.2007.08.004 (Pubitemid 47625318)
    • (2007) Archives of Physical Medicine and Rehabilitation , vol.88 , Issue.11 , pp. 1384-1393
    • Davies, A.L.1    Hayes, K.C.2    Dekaban, G.A.3
  • 42
    • 79951652761 scopus 로고    scopus 로고
    • Spinal astrocytes as therapeutic targets for pathological pain
    • 21081837 10.1254/jphs.10R04CP 1:CAS:528:DC%2BC3MXisFOnuw%3D%3D
    • T Nakagawa 2010 Spinal astrocytes as therapeutic targets for pathological pain J Pharmacol Sci 114 347 353 21081837 10.1254/jphs.10R04CP 1:CAS:528:DC%2BC3MXisFOnuw%3D%3D
    • (2010) J Pharmacol Sci , vol.114 , pp. 347-353
    • Nakagawa, T.1


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.