Contribution of a common variant in the promoter of the 1-α-hydroxylase gene (CYP27B1) to fracture risk in the elderly

Calcified Tissue International

Volumn 88, Issue 2, 2011, Pages 109-116

  Clifton Bligh, Roderick J ^a   Nguyen, Tuan V ^d,e   Au, Amy ^a   Bullock, Martyn ^a   Cameron, Ian ^b   Cumming, Robert ^c   Chen, Jian Sheng ^a   March, Lyn M ^a   Seibel, Markus J ^b   Sambrook, Philip N ^a  

^a ROYAL NORTH SHORE HOSPITAL   (Australia)

^b UNIVERSITY OF SYDNEY   (Australia)

^c UNIVERSITY OF SYDNEY   (Australia)

^d ST VINCENT S HOSPITAL   (Australia)

^e UNIVERSITY OF NEW SOUTH WALES   (Australia)

Author keywords

1 hydroxylase; CYP27B1; Fracture; Osteoporosis; Vitamin D

Indexed keywords

25 HYDROXYVITAMIN D; OXYGENASE; PARATHYROID HORMONE;

AGED; ARTICLE; BINDING SITE; CONTROLLED STUDY; CYP27B1 GENE; ELDERLY CARE; FEMALE; FRACTURE; FRAGILITY FRACTURE; GENE; GENE EXPRESSION; GENE FREQUENCY; GENE LINKAGE DISEQUILIBRIUM; GENETIC ASSOCIATION; GENETIC POLYMORPHISM; GENETIC RISK; GENETIC SUSCEPTIBILITY; GENETIC TRANSFECTION; GENETIC VARIABILITY; GENOTYPE; HETEROZYGOSITY; HOMOZYGOSITY; HUMAN; MAJOR CLINICAL STUDY; MALE; PRIORITY JOURNAL; PROMOTER REGION; PROTEIN BINDING; REPORTER GENE; RESTRICTION FRAGMENT LENGTH POLYMORPHISM; RISK ASSESSMENT; SINGLE NUCLEOTIDE POLYMORPHISM; VITAMIN D DEFICIENCY;

25-HYDROXYVITAMIN D3 1-ALPHA-HYDROXYLASE; AGED; AGED, 80 AND OVER; ALLELES; FEMALE; FRACTURES, BONE; GENETIC PREDISPOSITION TO DISEASE; GENETIC VARIATION; GENOTYPE; HUMANS; MALE; POLYMORPHISM, GENETIC; PROMOTER REGIONS, GENETIC; RISK; VITAMIN D;

EID: 79954429497     PISSN: 0171967X     EISSN: None     Source Type: Journal    
DOI: 10.1007/s00223-010-9434-4     Document Type: Article

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