Synthesis of fluorinated purine and 1-deazapurine glycosides as potential inhibitors of adenosine deaminase

Journal of Organic Chemistry

Volumn 76, Issue 8, 2011, Pages 2899-2903

  Iaroshenko, Viktor O ^a,b   Ostrovskyi, Dmytro ^a,b   Petrosyan, Andranik ^a   Mkrtchyan, Satenik ^a   Villinger, Alexander ^a   Langer, Peter ^a  

^a UNIVERSITY OF ROSTOCK   (Germany)

^b TARAS SHEVCHENKO NATIONAL UNIVERSITY OF KYIV   (Ukraine)

Author keywords

[No Author keywords available]

Indexed keywords

ADENOSINE DEAMINASES; CYCLIZATION REACTIONS; DEPROTECTION; DIELECTROPHILES; INOSINE MONOPHOSPHATE DEHYDROGENASE; POTENTIAL INHIBITORS; TRIFLUOROMETHYL;

GLUCOSE; SCAFFOLDS;

CYCLIZATION;

1 DEAZAPURINE; 2 TRIFLUOROMETHYLATED PURINE; 6 TRIFLUOROMETHYLATED PURINE; ADENOSINE DEAMINASE; ADENOSINE DEAMINASE INHIBITOR; GLUCOSE; NUCLEOSIDE; PURINE DERIVATIVE; RHAMNOSE; RIBOSE; UNCLASSIFIED DRUG;

ARTICLE; CYCLIZATION; DRUG SYNTHESIS; FLUORINATION; GLYCOSYLATION;

ADENOSINE DEAMINASE; ADENOSINE DEAMINASE INHIBITORS; CYCLIZATION; GLYCOSIDES; GLYCOSYLATION; HALOGENATION; HUMANS; IMIDAZOLES; IMP DEHYDROGENASE; MOLECULAR MIMICRY; MONOSACCHARIDES; PURINES;

EID: 79953875882     PISSN: 00223263     EISSN: 15206904     Source Type: Journal    
DOI: 10.1021/jo102579g     Document Type: Article

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