-
1
-
-
34547108380
-
JAK-STAT signaling: from interferons to cytokines
-
10.1074/jbc.R700016200, 17502367
-
Schindler C, Levy DE, Decker T. JAK-STAT signaling: from interferons to cytokines. J Biol Chem 2007, 282(28):20059-20063. 10.1074/jbc.R700016200, 17502367.
-
(2007)
J Biol Chem
, vol.282
, Issue.28
, pp. 20059-20063
-
-
Schindler, C.1
Levy, D.E.2
Decker, T.3
-
2
-
-
7944233465
-
Role of STATs as downstream signal transducers in Src family kinase-mediated tumorigenesis
-
10.1038/sj.onc.1208159, 15489919
-
Silva CM. Role of STATs as downstream signal transducers in Src family kinase-mediated tumorigenesis. Oncogene 2004, 23(48):8017-8023. 10.1038/sj.onc.1208159, 15489919.
-
(2004)
Oncogene
, vol.23
, Issue.48
, pp. 8017-8023
-
-
Silva, C.M.1
-
3
-
-
7244255836
-
Getting the message across, STAT! Design principles of a molecular signaling circuit
-
10.1083/jcb.200407163, 2172545, 15504906
-
Vinkemeier U. Getting the message across, STAT! Design principles of a molecular signaling circuit. J Cell Biol 2004, 167(2):197-201. 10.1083/jcb.200407163, 2172545, 15504906.
-
(2004)
J Cell Biol
, vol.167
, Issue.2
, pp. 197-201
-
-
Vinkemeier, U.1
-
4
-
-
0039115156
-
Transport into and out of the cell nucleus
-
10.1093/emboj/17.10.2721, 1170612, 9582265
-
Gorlich D. Transport into and out of the cell nucleus. Embo J 1998, 17(10):2721-2727. 10.1093/emboj/17.10.2721, 1170612, 9582265.
-
(1998)
Embo J
, vol.17
, Issue.10
, pp. 2721-2727
-
-
Gorlich, D.1
-
5
-
-
0042206459
-
A novel sequence in the coiled-coil domain of Stat3 essential for its nuclear translocation
-
10.1074/jbc.M304196200, 12746441
-
Ma J, Zhang T, Novotny-Diermayr V, Tan AL, Cao X. A novel sequence in the coiled-coil domain of Stat3 essential for its nuclear translocation. J Biol Chem 2003, 278(31):29252-29260. 10.1074/jbc.M304196200, 12746441.
-
(2003)
J Biol Chem
, vol.278
, Issue.31
, pp. 29252-29260
-
-
Ma, J.1
Zhang, T.2
Novotny-Diermayr, V.3
Tan, A.L.4
Cao, X.5
-
6
-
-
34247600538
-
STAT3 as a central mediator of neoplastic cellular transformation
-
10.1016/j.canlet.2006.10.017, 17129668
-
Frank DA. STAT3 as a central mediator of neoplastic cellular transformation. Cancer Lett 2007, 251(2):199-210. 10.1016/j.canlet.2006.10.017, 17129668.
-
(2007)
Cancer Lett
, vol.251
, Issue.2
, pp. 199-210
-
-
Frank, D.A.1
-
7
-
-
0036318564
-
Identification of a nuclear Stat1 protein tyrosine phosphatase
-
10.1128/MCB.22.16.5662-5668.2002, 133976, 12138178
-
ten Hoeve J, de Jesus Ibarra-Sanchez M, Fu Y, Zhu W, Tremblay M, David M, Shuai K. Identification of a nuclear Stat1 protein tyrosine phosphatase. Mol Cell Biol 2002, 22(16):5662-5668. 10.1128/MCB.22.16.5662-5668.2002, 133976, 12138178.
-
(2002)
Mol Cell Biol
, vol.22
, Issue.16
, pp. 5662-5668
-
-
ten Hoeve, J.1
de Jesus Ibarra-Sanchez, M.2
Fu, Y.3
Zhu, W.4
Tremblay, M.5
David, M.6
Shuai, K.7
-
8
-
-
0037327154
-
Regulation of Stat3 nuclear export
-
151917, 12588893
-
Bhattacharya S, Schindler C. Regulation of Stat3 nuclear export. J Clin Invest 2003, 111(4):553-559. 151917, 12588893.
-
(2003)
J Clin Invest
, vol.111
, Issue.4
, pp. 553-559
-
-
Bhattacharya, S.1
Schindler, C.2
-
9
-
-
0035142665
-
Activation of STAT proteins and growth control
-
10.1002/1521-1878(200102)23:2<161::AID-BIES1023>3.0.CO;2-0, 11169589
-
Bromberg JF. Activation of STAT proteins and growth control. Bioessays 2001, 23(2):161-169. 10.1002/1521-1878(200102)23:2<161::AID-BIES1023>3.0.CO;2-0, 11169589.
-
(2001)
Bioessays
, vol.23
, Issue.2
, pp. 161-169
-
-
Bromberg, J.F.1
-
10
-
-
0036251154
-
Stat proteins and oncogenesis
-
150969, 11994401
-
Bromberg J. Stat proteins and oncogenesis. J Clin Invest 2002, 109(9):1139-1142. 150969, 11994401.
-
(2002)
J Clin Invest
, vol.109
, Issue.9
, pp. 1139-1142
-
-
Bromberg, J.1
-
11
-
-
38849199799
-
STAT3 as a target for inducing apoptosis in solid and hematological tumors
-
10.1038/cr.2008.18, 2610254, 18227858
-
Al Zaid Siddiquee K, Turkson J. STAT3 as a target for inducing apoptosis in solid and hematological tumors. Cell Res 2008, 18(2):254-267. 10.1038/cr.2008.18, 2610254, 18227858.
-
(2008)
Cell Res
, vol.18
, Issue.2
, pp. 254-267
-
-
Al Zaid Siddiquee, K.1
Turkson, J.2
-
12
-
-
0033529704
-
Stat3 as an oncogene
-
10.1016/S0092-8674(00)81959-5, 10458605
-
Bromberg JF, Wrzeszczynska MH, Devgan G, Zhao Y, Pestell RG, Albanese C, Darnell JE. Stat3 as an oncogene. Cell 1999, 98(3):295-303. 10.1016/S0092-8674(00)81959-5, 10458605.
-
(1999)
Cell
, vol.98
, Issue.3
, pp. 295-303
-
-
Bromberg, J.F.1
Wrzeszczynska, M.H.2
Devgan, G.3
Zhao, Y.4
Pestell, R.G.5
Albanese, C.6
Darnell, J.E.7
-
13
-
-
0030935260
-
Targeted disruption of the mouse Stat3 gene leads to early embryonic lethality
-
10.1073/pnas.94.8.3801, 20521, 9108058
-
Takeda K, Noguchi K, Shi W, Tanaka T, Matsumoto M, Yoshida N, Kishimoto T, Akira S. Targeted disruption of the mouse Stat3 gene leads to early embryonic lethality. Proc Natl Acad Sci USA 1997, 94(8):3801-3804. 10.1073/pnas.94.8.3801, 20521, 9108058.
-
(1997)
Proc Natl Acad Sci USA
, vol.94
, Issue.8
, pp. 3801-3804
-
-
Takeda, K.1
Noguchi, K.2
Shi, W.3
Tanaka, T.4
Matsumoto, M.5
Yoshida, N.6
Kishimoto, T.7
Akira, S.8
-
14
-
-
21344436180
-
Malignant transformation but not normal cell growth depends on signal transducer and activator of transcription 3
-
10.1158/0008-5472.CAN-05-0317, 2100417, 15994959
-
Schlessinger K, Levy DE. Malignant transformation but not normal cell growth depends on signal transducer and activator of transcription 3. Cancer Res 2005, 65(13):5828-5834. 10.1158/0008-5472.CAN-05-0317, 2100417, 15994959.
-
(2005)
Cancer Res
, vol.65
, Issue.13
, pp. 5828-5834
-
-
Schlessinger, K.1
Levy, D.E.2
-
15
-
-
51349137454
-
Curcumin inhibits proliferation, invasion, angiogenesis and metastasis of different cancers through interaction with multiple cell signaling proteins
-
10.1016/j.canlet.2008.03.009, 18479807
-
Kunnumakkara AB, Anand P, Aggarwal BB. Curcumin inhibits proliferation, invasion, angiogenesis and metastasis of different cancers through interaction with multiple cell signaling proteins. Cancer Lett 2008, 269(2):199-225. 10.1016/j.canlet.2008.03.009, 18479807.
-
(2008)
Cancer Lett
, vol.269
, Issue.2
, pp. 199-225
-
-
Kunnumakkara, A.B.1
Anand, P.2
Aggarwal, B.B.3
-
16
-
-
33750982120
-
Stattic: a small-molecule inhibitor of STAT3 activation and dimerization
-
10.1016/j.chembiol.2006.09.018, 17114005
-
Schust J, Sperl B, Hollis A, Mayer TU, Berg T. Stattic: a small-molecule inhibitor of STAT3 activation and dimerization. Chem Biol 2006, 13(11):1235-1242. 10.1016/j.chembiol.2006.09.018, 17114005.
-
(2006)
Chem Biol
, vol.13
, Issue.11
, pp. 1235-1242
-
-
Schust, J.1
Sperl, B.2
Hollis, A.3
Mayer, T.U.4
Berg, T.5
-
17
-
-
64149102805
-
Efficient killing of SW480 colon carcinoma cells by a STAT3 hairpin decoy oligodeoxynucleotide. Interference with interferon gamma-STAT1-mediated killing
-
10.1111/j.1742-4658.2009.06975.x, 19476491
-
Tadlaoui Hbibi A, Laguillier C, Souissi I, Lesage D, Le Coquil S, Cao A, Metelev V, Baran-Marszak F, Fagard R. Efficient killing of SW480 colon carcinoma cells by a STAT3 hairpin decoy oligodeoxynucleotide. Interference with interferon gamma-STAT1-mediated killing. FEBS Journal 2009, 276:2505-2515. 10.1111/j.1742-4658.2009.06975.x, 19476491.
-
(2009)
FEBS Journal
, vol.276
, pp. 2505-2515
-
-
Tadlaoui Hbibi, A.1
Laguillier, C.2
Souissi, I.3
Lesage, D.4
Le Coquil, S.5
Cao, A.6
Metelev, V.7
Baran-Marszak, F.8
Fagard, R.9
-
18
-
-
0141953974
-
Transcription factors as molecular targets: molecular mechanisms of decoy ODN and their design
-
10.2174/1389450033490803, 14577649
-
Tomita N, Ogihara T, Morishita R. Transcription factors as molecular targets: molecular mechanisms of decoy ODN and their design. Curr Drug Targets 2003, 4(8):603-608. 10.2174/1389450033490803, 14577649.
-
(2003)
Curr Drug Targets
, vol.4
, Issue.8
, pp. 603-608
-
-
Tomita, N.1
Ogihara, T.2
Morishita, R.3
-
19
-
-
64849111865
-
Targeting STAT3 in cancer: how successful are we?
-
10.1517/13543780802565791, 2610472, 19053881
-
Yue P, Turkson J. Targeting STAT3 in cancer: how successful are we?. Expert Opin Investig Drugs 2009, 18(1):45-56. 10.1517/13543780802565791, 2610472, 19053881.
-
(2009)
Expert Opin Investig Drugs
, vol.18
, Issue.1
, pp. 45-56
-
-
Yue, P.1
Turkson, J.2
-
20
-
-
34548707231
-
Selective inactivation of NF-kappaB in the liver using NF-kappaB decoy suppresses CCl4-induced liver injury and fibrosis
-
10.1152/ajpgi.00185.2007, 17640975
-
Son G, Iimuro Y, Seki E, Hirano T, Kaneda Y, Fujimoto J. Selective inactivation of NF-kappaB in the liver using NF-kappaB decoy suppresses CCl4-induced liver injury and fibrosis. Am J Physiol Gastrointest Liver Physiol 2007, 293(3):G631-639. 10.1152/ajpgi.00185.2007, 17640975.
-
(2007)
Am J Physiol Gastrointest Liver Physiol
, vol.293
, Issue.3
-
-
Son, G.1
Iimuro, Y.2
Seki, E.3
Hirano, T.4
Kaneda, Y.5
Fujimoto, J.6
-
21
-
-
33947103197
-
Cell death in NF-kappaB-dependent tumour cell lines as a result of NF-kappaB trapping by linker-modified hairpin decoy oligonucleotide
-
10.1016/j.febslet.2007.02.024, 17328896
-
Laguillier C, Hbibi AT, Baran-Marszak F, Metelev V, Cao A, Cymbalista F, Bogdanov A, Fagard R. Cell death in NF-kappaB-dependent tumour cell lines as a result of NF-kappaB trapping by linker-modified hairpin decoy oligonucleotide. FEBS Lett 2007, 581(6):1143-1150. 10.1016/j.febslet.2007.02.024, 17328896.
-
(2007)
FEBS Lett
, vol.581
, Issue.6
, pp. 1143-1150
-
-
Laguillier, C.1
Hbibi, A.T.2
Baran-Marszak, F.3
Metelev, V.4
Cao, A.5
Cymbalista, F.6
Bogdanov, A.7
Fagard, R.8
-
22
-
-
0037386568
-
Targeted inhibition of Stat3 with a decoy oligonucleotide abrogates head and neck cancer cell growth
-
10.1073/pnas.0534764100, 153061, 12640143
-
Leong PL, Andrews GA, Johnson DE, Dyer KF, Xi S, Mai JC, Robbins PD, Gadiparthi S, Burke NA, Watkins SF, et al. Targeted inhibition of Stat3 with a decoy oligonucleotide abrogates head and neck cancer cell growth. Proc Natl Acad Sci USA 2003, 100(7):4138-4143. 10.1073/pnas.0534764100, 153061, 12640143.
-
(2003)
Proc Natl Acad Sci USA
, vol.100
, Issue.7
, pp. 4138-4143
-
-
Leong, P.L.1
Andrews, G.A.2
Johnson, D.E.3
Dyer, K.F.4
Xi, S.5
Mai, J.C.6
Robbins, P.D.7
Gadiparthi, S.8
Burke, N.A.9
Watkins, S.F.10
-
23
-
-
33947574564
-
Targeting signal-transducer-and-activator-of-transcription-3 for prevention and therapy of cancer: modern target but ancient solution
-
10.1196/annals.1378.063, 17341611
-
Aggarwal BB, Sethi G, Ahn KS, Sandur SK, Pandey MK, Kunnumakkara AB, Sung B, Ichikawa H. Targeting signal-transducer-and-activator-of-transcription-3 for prevention and therapy of cancer: modern target but ancient solution. Ann N Y Acad Sci 2006, 1091:151-169. 10.1196/annals.1378.063, 17341611.
-
(2006)
Ann N Y Acad Sci
, vol.1091
, pp. 151-169
-
-
Aggarwal, B.B.1
Sethi, G.2
Ahn, K.S.3
Sandur, S.K.4
Pandey, M.K.5
Kunnumakkara, A.B.6
Sung, B.7
Ichikawa, H.8
-
24
-
-
40649087829
-
Growth inhibition of human hepatocellular carcinoma cells by blocking STAT3 activation with decoy-ODN
-
10.1016/j.canlet.2007.12.009, 18248786
-
Sun X, Zhang J, Wang L, Tian Z. Growth inhibition of human hepatocellular carcinoma cells by blocking STAT3 activation with decoy-ODN. Cancer Letters 2008, 262(2):201-213. 10.1016/j.canlet.2007.12.009, 18248786.
-
(2008)
Cancer Letters
, vol.262
, Issue.2
, pp. 201-213
-
-
Sun, X.1
Zhang, J.2
Wang, L.3
Tian, Z.4
-
25
-
-
13944250650
-
In vivo antitumor efficacy of STAT3 blockade using a transcription factor decoy approach: implications for cancer therapy
-
10.1038/sj.onc.1208316, 15592503
-
Xi S, Gooding WE, Grandis JR. In vivo antitumor efficacy of STAT3 blockade using a transcription factor decoy approach: implications for cancer therapy. Oncogene 2005, 24(6):970-979. 10.1038/sj.onc.1208316, 15592503.
-
(2005)
Oncogene
, vol.24
, Issue.6
, pp. 970-979
-
-
Xi, S.1
Gooding, W.E.2
Grandis, J.R.3
-
26
-
-
0035794217
-
DNA binding specificity of different STAT proteins. Comparison of in vitro specificity with natural target sites
-
10.1074/jbc.M001748200, 11053426
-
Ehret GB, Reichenbach P, Schindler U, Horvath CM, Fritz S, Nabholz M, Bucher P. DNA binding specificity of different STAT proteins. Comparison of in vitro specificity with natural target sites. J Biol Chem 2001, 276(9):6675-6688. 10.1074/jbc.M001748200, 11053426.
-
(2001)
J Biol Chem
, vol.276
, Issue.9
, pp. 6675-6688
-
-
Ehret, G.B.1
Reichenbach, P.2
Schindler, U.3
Horvath, C.M.4
Fritz, S.5
Nabholz, M.6
Bucher, P.7
-
27
-
-
0033928439
-
Transcription factor decoy for NFkappaB inhibits cytokine and adhesion molecule expressions in synovial cells derived from rheumatoid arthritis
-
10.1093/rheumatology/39.7.749, 10908694
-
Tomita T, Takano H, Tomita N, Morishita R, Kaneko M, Shi K, Takahi K, Nakase T, Kaneda Y, Yoshikawa H, et al. Transcription factor decoy for NFkappaB inhibits cytokine and adhesion molecule expressions in synovial cells derived from rheumatoid arthritis. Rheumatology (Oxford) 2000, 39(7):749-757. 10.1093/rheumatology/39.7.749, 10908694.
-
(2000)
Rheumatology (Oxford)
, vol.39
, Issue.7
, pp. 749-757
-
-
Tomita, T.1
Takano, H.2
Tomita, N.3
Morishita, R.4
Kaneko, M.5
Shi, K.6
Takahi, K.7
Nakase, T.8
Kaneda, Y.9
Yoshikawa, H.10
-
28
-
-
0001611720
-
Dual blockade of cyclic AMP response element- (CRE) and AP-1-directed transcription by CRE-transcription factor decoy oligonucleotide. gene-specific inhibition of tumor growth
-
10.1074/jbc.274.3.1573, 9880535
-
Park YG, Nesterova M, Agrawal S, Cho-Chung YS. Dual blockade of cyclic AMP response element- (CRE) and AP-1-directed transcription by CRE-transcription factor decoy oligonucleotide. gene-specific inhibition of tumor growth. J Biol Chem 1999, 274(3):1573-1580. 10.1074/jbc.274.3.1573, 9880535.
-
(1999)
J Biol Chem
, vol.274
, Issue.3
, pp. 1573-1580
-
-
Park, Y.G.1
Nesterova, M.2
Agrawal, S.3
Cho-Chung, Y.S.4
-
29
-
-
19644380361
-
Subcellular localization as a limiting factor for utilization of decoy oligonucleotides
-
10.1093/nar/gnh139, 528816, 15498923
-
Bene A, Kurten RC, Chambers TC. Subcellular localization as a limiting factor for utilization of decoy oligonucleotides. Nucleic Acids Res 2004, 32(19):e142. 10.1093/nar/gnh139, 528816, 15498923.
-
(2004)
Nucleic Acids Res
, vol.32
, Issue.19
-
-
Bene, A.1
Kurten, R.C.2
Chambers, T.C.3
-
30
-
-
27244436612
-
Targeted disruption of transcriptional regulatory function of p53 by a novel efficient method for introducing a decoy oligonucleotide into nuclei
-
10.1093/nar/gni088, 1140756, 15920103
-
Sakaguchi M, Nukui T, Sonegawa H, Murata H, Futami J, Yamada H, Huh NH. Targeted disruption of transcriptional regulatory function of p53 by a novel efficient method for introducing a decoy oligonucleotide into nuclei. Nucleic Acids Res 2005, 33(9):e88. 10.1093/nar/gni088, 1140756, 15920103.
-
(2005)
Nucleic Acids Res
, vol.33
, Issue.9
-
-
Sakaguchi, M.1
Nukui, T.2
Sonegawa, H.3
Murata, H.4
Futami, J.5
Yamada, H.6
Huh, N.H.7
-
31
-
-
35549007501
-
Nucleocytoplasmic shuttling of persistently activated STAT3
-
10.1242/jcs.03482, 17726064
-
Herrmann A, Vogt M, Monnigmann M, Clahsen T, Sommer U, Haan S, Poli V, Heinrich PC, Muller-Newen G. Nucleocytoplasmic shuttling of persistently activated STAT3. J Cell Sci 2007, 120(Pt 18):3249-3261. 10.1242/jcs.03482, 17726064.
-
(2007)
J Cell Sci
, vol.120
, Issue.PART 18
, pp. 3249-3261
-
-
Herrmann, A.1
Vogt, M.2
Monnigmann, M.3
Clahsen, T.4
Sommer, U.5
Haan, S.6
Poli, V.7
Heinrich, P.C.8
Muller-Newen, G.9
-
32
-
-
20444400857
-
STAT3 nuclear import is independent of tyrosine phosphorylation and mediated by importin-alpha3
-
10.1073/pnas.0501643102, 1149424, 15919823
-
Liu L, McBride KM, Reich NC. STAT3 nuclear import is independent of tyrosine phosphorylation and mediated by importin-alpha3. Proc Natl Acad Sci USA 2005, 102(23):8150-8155. 10.1073/pnas.0501643102, 1149424, 15919823.
-
(2005)
Proc Natl Acad Sci USA
, vol.102
, Issue.23
, pp. 8150-8155
-
-
Liu, L.1
McBride, K.M.2
Reich, N.C.3
-
33
-
-
35348944884
-
STAT nuclear translocation: potential for pharmacological intervention
-
10.1517/14728222.11.10.1355, 17907964
-
Meyer T, Vinkemeier U. STAT nuclear translocation: potential for pharmacological intervention. Expert Opin Ther Targets 2007, 11(10):1355-1365. 10.1517/14728222.11.10.1355, 17907964.
-
(2007)
Expert Opin Ther Targets
, vol.11
, Issue.10
, pp. 1355-1365
-
-
Meyer, T.1
Vinkemeier, U.2
-
34
-
-
40749103000
-
A signal network involving coactivated NF-kappaB and STAT3 and altered p53 modulates BAX/BCL-XL expression and promotes cell survival of head and neck squamous cell carcinomas
-
10.1002/ijc.23324, 18172861
-
Lee TL, Yeh J, Friedman J, Yan B, Yang X, Yeh NT, Van Waes C, Chen Z. A signal network involving coactivated NF-kappaB and STAT3 and altered p53 modulates BAX/BCL-XL expression and promotes cell survival of head and neck squamous cell carcinomas. Int J Cancer 2008, 122(9):1987-1998. 10.1002/ijc.23324, 18172861.
-
(2008)
Int J Cancer
, vol.122
, Issue.9
, pp. 1987-1998
-
-
Lee, T.L.1
Yeh, J.2
Friedman, J.3
Yan, B.4
Yang, X.5
Yeh, N.T.6
Van Waes, C.7
Chen, Z.8
-
35
-
-
77549083560
-
Dangerous liaisons: STAT3 and NF-kappaB collaboration and crosstalk in cancer
-
10.1016/j.cytogfr.2009.11.005, 2834864, 20018552
-
Grivennikov SI, Karin M. Dangerous liaisons: STAT3 and NF-kappaB collaboration and crosstalk in cancer. Cytokine Growth Factor Rev 2010, 21(1):11-19. 10.1016/j.cytogfr.2009.11.005, 2834864, 20018552.
-
(2010)
Cytokine Growth Factor Rev
, vol.21
, Issue.1
, pp. 11-19
-
-
Grivennikov, S.I.1
Karin, M.2
-
36
-
-
0028913109
-
A STAT protein domain that determines DNA sequence recognition suggests a novel DNA-binding domain
-
10.1101/gad.9.8.984, 7774815
-
Horvath CM, Wen Z, Darnell JE. A STAT protein domain that determines DNA sequence recognition suggests a novel DNA-binding domain. Genes Dev 1995, 9(8):984-994. 10.1101/gad.9.8.984, 7774815.
-
(1995)
Genes Dev
, vol.9
, Issue.8
, pp. 984-994
-
-
Horvath, C.M.1
Wen, Z.2
Darnell, J.E.3
-
37
-
-
77953988626
-
STAT1-dependent IgG cell-surface expression in a human B cell line derived from a STAT1-deficient patient
-
Najjar I, Deglesne PA, Schischmanoff PO, Fabre EE, Boisson-Dupuis S, Nimmerjahn F, Bornkamm GW, Dusanter-Fourt I, Fagard R. STAT1-dependent IgG cell-surface expression in a human B cell line derived from a STAT1-deficient patient. J Leukoc Biol 2010,
-
(2010)
J Leukoc Biol
-
-
Najjar, I.1
Deglesne, P.A.2
Schischmanoff, P.O.3
Fabre, E.E.4
Boisson-Dupuis, S.5
Nimmerjahn, F.6
Bornkamm, G.W.7
Dusanter-Fourt, I.8
Fagard, R.9
-
38
-
-
40049093105
-
Inhibition of signal transducer and activator of transcription 3 expression by RNA interference suppresses invasion through inducing anoikis in human colon cancer cells
-
10.3748/wjg.14.428, 2679132, 18200666
-
Fan Y, Zhang YL, Wu Y, Zhang W, Wang YH, Cheng ZM, Li H. Inhibition of signal transducer and activator of transcription 3 expression by RNA interference suppresses invasion through inducing anoikis in human colon cancer cells. World J Gastroenterol 2008, 14(3):428-434. 10.3748/wjg.14.428, 2679132, 18200666.
-
(2008)
World J Gastroenterol
, vol.14
, Issue.3
, pp. 428-434
-
-
Fan, Y.1
Zhang, Y.L.2
Wu, Y.3
Zhang, W.4
Wang, Y.H.5
Cheng, Z.M.6
Li, H.7
-
39
-
-
0025639009
-
The SIF binding element confers sis/PDGF inducibility onto the c-fos promoter
-
552240, 2176154
-
Wagner BJ, Hayes TE, Hoban CJ, Cochran BH. The SIF binding element confers sis/PDGF inducibility onto the c-fos promoter. EMBO J 1990, 9(13):4477-4484. 552240, 2176154.
-
(1990)
EMBO J
, vol.9
, Issue.13
, pp. 4477-4484
-
-
Wagner, B.J.1
Hayes, T.E.2
Hoban, C.J.3
Cochran, B.H.4
-
40
-
-
0036875445
-
In vitro and in vivo transfection of melanoma cells B16-F10 mediated by cholesterol-based cationic liposomes
-
10.1080/1061186021000038049, 12683723
-
Reynier P, Briane D, Cao A, Lievre N, Naejus R, Bissieres P, Salzmann JL, Taillandier E. In vitro and in vivo transfection of melanoma cells B16-F10 mediated by cholesterol-based cationic liposomes. J Drug Target 2002, 10(7):557-566. 10.1080/1061186021000038049, 12683723.
-
(2002)
J Drug Target
, vol.10
, Issue.7
, pp. 557-566
-
-
Reynier, P.1
Briane, D.2
Cao, A.3
Lievre, N.4
Naejus, R.5
Bissieres, P.6
Salzmann, J.L.7
Taillandier, E.8
-
41
-
-
26244463218
-
Constitutive activation of JAK3/STAT3 in colon carcinoma tumors and cell lines: inhibition of JAK3/STAT3 signaling induces apoptosis and cell cycle arrest of colon carcinoma cells
-
10.1016/S0002-9440(10)61187-X, 1603671, 16192633
-
Lin Q, Lai R, Chirieac LR, Li C, Thomazy VA, Grammatikakis I, Rassidakis GZ, Zhang W, Fujio Y, Kunisada K, et al. Constitutive activation of JAK3/STAT3 in colon carcinoma tumors and cell lines: inhibition of JAK3/STAT3 signaling induces apoptosis and cell cycle arrest of colon carcinoma cells. Am J Pathol 2005, 167(4):969-980. 10.1016/S0002-9440(10)61187-X, 1603671, 16192633.
-
(2005)
Am J Pathol
, vol.167
, Issue.4
, pp. 969-980
-
-
Lin, Q.1
Lai, R.2
Chirieac, L.R.3
Li, C.4
Thomazy, V.A.5
Grammatikakis, I.6
Rassidakis, G.Z.7
Zhang, W.8
Fujio, Y.9
Kunisada, K.10
-
42
-
-
33947524972
-
Expression of SOCS1 and SOCS3 genes is differentially regulated in breast cancer cells in response to proinflammatory cytokine and growth factor signals
-
10.1038/sj.onc.1209993, 17001312
-
Evans MK, Yu CR, Lohani A, Mahdi RM, Liu X, Trzeciak AR, Egwuagu CE. Expression of SOCS1 and SOCS3 genes is differentially regulated in breast cancer cells in response to proinflammatory cytokine and growth factor signals. Oncogene 2007, 26(13):1941-1948. 10.1038/sj.onc.1209993, 17001312.
-
(2007)
Oncogene
, vol.26
, Issue.13
, pp. 1941-1948
-
-
Evans, M.K.1
Yu, C.R.2
Lohani, A.3
Mahdi, R.M.4
Liu, X.5
Trzeciak, A.R.6
Egwuagu, C.E.7
-
43
-
-
33845501610
-
Phosphotyrosine profiling identifies the KG-1 cell line as a model for the study of FGFR1 fusions in acute myeloid leukemia
-
10.1182/blood-2006-06-026666, 16946300
-
Gu TL, Goss VL, Reeves C, Popova L, Nardone J, Macneill J, Walters DK, Wang Y, Rush J, Comb MJ, et al. Phosphotyrosine profiling identifies the KG-1 cell line as a model for the study of FGFR1 fusions in acute myeloid leukemia. Blood 2006, 108(13):4202-4204. 10.1182/blood-2006-06-026666, 16946300.
-
(2006)
Blood
, vol.108
, Issue.13
, pp. 4202-4204
-
-
Gu, T.L.1
Goss, V.L.2
Reeves, C.3
Popova, L.4
Nardone, J.5
Macneill, J.6
Walters, D.K.7
Wang, Y.8
Rush, J.9
Comb, M.J.10
-
44
-
-
67649515378
-
Absence of STAT1 disturbs the anticancer effect induced by STAT3 inhibition in head and neck carcinoma cell lines
-
Shim SH, Sung MW, Park SW, Heo DS. Absence of STAT1 disturbs the anticancer effect induced by STAT3 inhibition in head and neck carcinoma cell lines. Int J Mol Med 2009, 23(6):805-810.
-
(2009)
Int J Mol Med
, vol.23
, Issue.6
, pp. 805-810
-
-
Shim, S.H.1
Sung, M.W.2
Park, S.W.3
Heo, D.S.4
-
45
-
-
0032868712
-
Loss of STAT1 expression confers resistance to IFN-gamma-induced apoptosis in ME180 cells
-
10.1016/S0014-5793(99)01283-1, 10526158
-
Lee KY, Anderson E, Madani K, Rosen GD. Loss of STAT1 expression confers resistance to IFN-gamma-induced apoptosis in ME180 cells. FEBS Lett 1999, 459(3):323-326. 10.1016/S0014-5793(99)01283-1, 10526158.
-
(1999)
FEBS Lett
, vol.459
, Issue.3
, pp. 323-326
-
-
Lee, K.Y.1
Anderson, E.2
Madani, K.3
Rosen, G.D.4
-
46
-
-
8544281698
-
STAT1: a modulator of chemotherapy-induced apoptosis
-
10.1158/0008-5472.CAN-04-1864, 15548705
-
Thomas M, Finnegan CE, Rogers KM, Purcell JW, Trimble A, Johnston PG, Boland MP. STAT1: a modulator of chemotherapy-induced apoptosis. Cancer Res 2004, 64(22):8357-8364. 10.1158/0008-5472.CAN-04-1864, 15548705.
-
(2004)
Cancer Res
, vol.64
, Issue.22
, pp. 8357-8364
-
-
Thomas, M.1
Finnegan, C.E.2
Rogers, K.M.3
Purcell, J.W.4
Trimble, A.5
Johnston, P.G.6
Boland, M.P.7
-
47
-
-
2442577024
-
A single residue modulates tyrosine dephosphorylation, oligomerization, and nuclear accumulation of stat transcription factors
-
10.1074/jbc.M400766200, 15010467
-
Meyer T, Hendry L, Begitt A, John S, Vinkemeier U. A single residue modulates tyrosine dephosphorylation, oligomerization, and nuclear accumulation of stat transcription factors. J Biol Chem 2004, 279(18):18998-19007. 10.1074/jbc.M400766200, 15010467.
-
(2004)
J Biol Chem
, vol.279
, Issue.18
, pp. 18998-19007
-
-
Meyer, T.1
Hendry, L.2
Begitt, A.3
John, S.4
Vinkemeier, U.5
-
48
-
-
0032146749
-
Leptomycin B inhibition of signal-mediated nuclear export by direct binding to CRM1
-
10.1006/excr.1998.4136, 9683540
-
Kudo N, Wolff B, Sekimoto T, Schreiner EP, Yoneda Y, Yanagida M, Horinouchi S, Yoshida M. Leptomycin B inhibition of signal-mediated nuclear export by direct binding to CRM1. Exp Cell Res 1998, 242(2):540-547. 10.1006/excr.1998.4136, 9683540.
-
(1998)
Exp Cell Res
, vol.242
, Issue.2
, pp. 540-547
-
-
Kudo, N.1
Wolff, B.2
Sekimoto, T.3
Schreiner, E.P.4
Yoneda, Y.5
Yanagida, M.6
Horinouchi, S.7
Yoshida, M.8
-
49
-
-
73849090217
-
IKK/NF-kappaB and STAT3 pathways: central signalling hubs in inflammation-mediated tumour promotion and metastasis
-
10.1038/embor.2009.243, 2799209, 19893576
-
Bollrath J, Greten FR. IKK/NF-kappaB and STAT3 pathways: central signalling hubs in inflammation-mediated tumour promotion and metastasis. EMBO Rep 2009, 10(12):1314-1319. 10.1038/embor.2009.243, 2799209, 19893576.
-
(2009)
EMBO Rep
, vol.10
, Issue.12
, pp. 1314-1319
-
-
Bollrath, J.1
Greten, F.R.2
-
50
-
-
54349127051
-
Molecular approaches towards the inhibition of the signal transducer and activator of transcription 3 (Stat3) protein
-
10.1002/cmdc.200800123, 2603136, 18683176
-
Fletcher S, Turkson J, Gunning PT. Molecular approaches towards the inhibition of the signal transducer and activator of transcription 3 (Stat3) protein. ChemMedChem 2008, 3(8):1159-1168. 10.1002/cmdc.200800123, 2603136, 18683176.
-
(2008)
ChemMedChem
, vol.3
, Issue.8
, pp. 1159-1168
-
-
Fletcher, S.1
Turkson, J.2
Gunning, P.T.3
-
51
-
-
20844444135
-
Targeting Stat3 in cancer therapy
-
10.1097/00001813-200507000-00002, 15930886
-
Jing N, Tweardy DJ. Targeting Stat3 in cancer therapy. Anticancer Drugs 2005, 16(6):601-607. 10.1097/00001813-200507000-00002, 15930886.
-
(2005)
Anticancer Drugs
, vol.16
, Issue.6
, pp. 601-607
-
-
Jing, N.1
Tweardy, D.J.2
-
52
-
-
33746570647
-
Tracking STAT nuclear traffic
-
10.1038/nri1885, 16868551
-
Reich NC, Liu L. Tracking STAT nuclear traffic. Nat Rev Immunol 2006, 6(8):602-612. 10.1038/nri1885, 16868551.
-
(2006)
Nat Rev Immunol
, vol.6
, Issue.8
, pp. 602-612
-
-
Reich, N.C.1
Liu, L.2
-
53
-
-
33646365075
-
Regulation of Stat3 nuclear import by importin alpha5 and importin alpha7 via two different functional sequence elements
-
10.1016/j.cellsig.2005.06.016, 16298512
-
Ma J, Cao X. Regulation of Stat3 nuclear import by importin alpha5 and importin alpha7 via two different functional sequence elements. Cell Signal 2006, 18(8):1117-1126. 10.1016/j.cellsig.2005.06.016, 16298512.
-
(2006)
Cell Signal
, vol.18
, Issue.8
, pp. 1117-1126
-
-
Ma, J.1
Cao, X.2
-
54
-
-
77956170743
-
Molecular basis for the recognition of phosphorylated STAT1 by importin alpha5
-
10.1016/j.jmb.2010.07.013, 20643137
-
Nardozzi J, Wenta N, Yasuhara N, Vinkemeier U, Cingolani G. Molecular basis for the recognition of phosphorylated STAT1 by importin alpha5. J Mol Biol 2010, 402(1):83-100. 10.1016/j.jmb.2010.07.013, 20643137.
-
(2010)
J Mol Biol
, vol.402
, Issue.1
, pp. 83-100
-
-
Nardozzi, J.1
Wenta, N.2
Yasuhara, N.3
Vinkemeier, U.4
Cingolani, G.5
-
55
-
-
2442504891
-
Real time analysis of STAT3 nucleocytoplasmic shuttling
-
10.1074/jbc.M312530200, 14701810
-
Pranada AL, Metz S, Herrmann A, Heinrich PC, Muller-Newen G. Real time analysis of STAT3 nucleocytoplasmic shuttling. J Biol Chem 2004, 279(15):15114-15123. 10.1074/jbc.M312530200, 14701810.
-
(2004)
J Biol Chem
, vol.279
, Issue.15
, pp. 15114-15123
-
-
Pranada, A.L.1
Metz, S.2
Herrmann, A.3
Heinrich, P.C.4
Muller-Newen, G.5
-
56
-
-
3042552337
-
Nucleocytoplasmic shuttling by nucleoporins Nup153 and Nup214 and CRM1-dependent nuclear export control the subcellular distribution of latent Stat1
-
10.1083/jcb.200403057, 2172394, 15210729
-
Marg A, Shan Y, Meyer T, Meissner T, Brandenburg M, Vinkemeier U. Nucleocytoplasmic shuttling by nucleoporins Nup153 and Nup214 and CRM1-dependent nuclear export control the subcellular distribution of latent Stat1. J Cell Biol 2004, 165(6):823-833. 10.1083/jcb.200403057, 2172394, 15210729.
-
(2004)
J Cell Biol
, vol.165
, Issue.6
, pp. 823-833
-
-
Marg, A.1
Shan, Y.2
Meyer, T.3
Meissner, T.4
Brandenburg, M.5
Vinkemeier, U.6
-
57
-
-
34249868449
-
Unphosphorylated STAT3 accumulates in response to IL-6 and activates transcription by binding to NFkappaB
-
10.1101/gad.1553707, 1877751, 17510282
-
Yang J, Liao X, Agarwal MK, Barnes L, Auron PE, Stark GR. Unphosphorylated STAT3 accumulates in response to IL-6 and activates transcription by binding to NFkappaB. Genes Dev 2007, 21(11):1396-1408. 10.1101/gad.1553707, 1877751, 17510282.
-
(2007)
Genes Dev
, vol.21
, Issue.11
, pp. 1396-1408
-
-
Yang, J.1
Liao, X.2
Agarwal, M.K.3
Barnes, L.4
Auron, P.E.5
Stark, G.R.6
-
58
-
-
41849116690
-
Roles of unphosphorylated STATs in signaling
-
10.1038/cr.2008.41, 18364677
-
Yang J, Stark GR. Roles of unphosphorylated STATs in signaling. Cell Res 2008, 18(4):443-451. 10.1038/cr.2008.41, 18364677.
-
(2008)
Cell Res
, vol.18
, Issue.4
, pp. 443-451
-
-
Yang, J.1
Stark, G.R.2
-
59
-
-
0030659512
-
Defective TNF-alpha-induced apoptosis in STAT1-null cells due to low constitutive levels of caspases
-
10.1126/science.278.5343.1630, 9374464
-
Kumar A, Commane M, Flickinger TW, Horvath CM, Stark GR. Defective TNF-alpha-induced apoptosis in STAT1-null cells due to low constitutive levels of caspases. Science 1997, 278(5343):1630-1632. 10.1126/science.278.5343.1630, 9374464.
-
(1997)
Science
, vol.278
, Issue.5343
, pp. 1630-1632
-
-
Kumar, A.1
Commane, M.2
Flickinger, T.W.3
Horvath, C.M.4
Stark, G.R.5
-
60
-
-
77951025336
-
STAT1 and pathogens, not a friendly relationship
-
10.1016/j.biochi.2010.02.009, 20159032
-
Najjar I, Fagard R. STAT1 and pathogens, not a friendly relationship. Biochimie 2010, 92:425-444. 10.1016/j.biochi.2010.02.009, 20159032.
-
(2010)
Biochimie
, vol.92
, pp. 425-444
-
-
Najjar, I.1
Fagard, R.2
-
61
-
-
0031935499
-
STATs as activators of apoptosis
-
10.1016/S0962-8924(98)01233-1, 9695817
-
Schindler C. STATs as activators of apoptosis. Trends Cell Biol 1998, 8(3):97-98. 10.1016/S0962-8924(98)01233-1, 9695817.
-
(1998)
Trends Cell Biol
, vol.8
, Issue.3
, pp. 97-98
-
-
Schindler, C.1
-
62
-
-
0037264972
-
The anti-proliferative activity of interferon-gamma on ovarian cancer: in vitro and in vivo
-
10.1006/gyno.2002.6707, 12586108
-
Wall L, Burke F, Smyth JF, Balkwill F. The anti-proliferative activity of interferon-gamma on ovarian cancer: in vitro and in vivo. Gynecol Oncol 2003, 88(1 Pt 2):S149-151. 10.1006/gyno.2002.6707, 12586108.
-
(2003)
Gynecol Oncol
, vol.88
, Issue.1 PART 2
-
-
Wall, L.1
Burke, F.2
Smyth, J.F.3
Balkwill, F.4
-
63
-
-
56849116562
-
Interferon-gamma inhibits cellular proliferation and ACTH production in corticotroph tumor cells through a novel janus kinases-signal transducer and activator of transcription 1/nuclear factor-kappa B inhibitory signaling pathway
-
10.1677/JOE-08-0011, 18715881
-
Labeur M, Refojo D, Wolfel B, Stalla J, Vargas V, Theodoropoulou M, Buchfelder M, Paez-Pereda M, Arzt E, Stalla GK. Interferon-gamma inhibits cellular proliferation and ACTH production in corticotroph tumor cells through a novel janus kinases-signal transducer and activator of transcription 1/nuclear factor-kappa B inhibitory signaling pathway. J Endocrinol 2008, 199(2):177-189. 10.1677/JOE-08-0011, 18715881.
-
(2008)
J Endocrinol
, vol.199
, Issue.2
, pp. 177-189
-
-
Labeur, M.1
Refojo, D.2
Wolfel, B.3
Stalla, J.4
Vargas, V.5
Theodoropoulou, M.6
Buchfelder, M.7
Paez-Pereda, M.8
Arzt, E.9
Stalla, G.K.10
-
64
-
-
38149058812
-
Signal transducer and activator of transcription 1 decoy oligodeoxynucleotide suppression of contact hypersensitivity
-
e155, 10.1016/j.jaci.2007.09.015, 17981315
-
Wagner AH, Wittjen I, Stojanovic T, Middel P, Meingassner JG, Hecker M. Signal transducer and activator of transcription 1 decoy oligodeoxynucleotide suppression of contact hypersensitivity. J Allergy Clin Immunol 2008, 121(1):158-165. e155, 10.1016/j.jaci.2007.09.015, 17981315.
-
(2008)
J Allergy Clin Immunol
, vol.121
, Issue.1
, pp. 158-165
-
-
Wagner, A.H.1
Wittjen, I.2
Stojanovic, T.3
Middel, P.4
Meingassner, J.G.5
Hecker, M.6
-
65
-
-
0029799912
-
Transcriptionally active Stat1 is required for the antiproliferative effects of both interferon alpha and interferon gamma
-
10.1073/pnas.93.15.7673, 38805, 8755534
-
Bromberg JF, Horvath CM, Wen Z, Schreiber RD, Darnell JE. Transcriptionally active Stat1 is required for the antiproliferative effects of both interferon alpha and interferon gamma. Proc Natl Acad Sci USA 1996, 93(15):7673-7678. 10.1073/pnas.93.15.7673, 38805, 8755534.
-
(1996)
Proc Natl Acad Sci USA
, vol.93
, Issue.15
, pp. 7673-7678
-
-
Bromberg, J.F.1
Horvath, C.M.2
Wen, Z.3
Schreiber, R.D.4
Darnell, J.E.5
-
66
-
-
52949136974
-
Ups and downs: The STAT1:STAT3 seesaw of Interferon and gp130 receptor signalling
-
Regis G, Pensa S, Boselli D, Novelli F, Poli V. Ups and downs: The STAT1:STAT3 seesaw of Interferon and gp130 receptor signalling. Semin Cell Dev Biol 2008,
-
(2008)
Semin Cell Dev Biol
-
-
Regis, G.1
Pensa, S.2
Boselli, D.3
Novelli, F.4
Poli, V.5
-
67
-
-
63949085226
-
Lack of toxicity of a STAT3 decoy oligonucleotide
-
10.1007/s00280-008-0823-6, 18766340
-
Sen M, Tosca PJ, Zwayer C, Ryan MJ, Johnson JD, Knostman KA, Giclas PC, Peggins JO, Tomaszewski JE, McMurray TP, et al. Lack of toxicity of a STAT3 decoy oligonucleotide. Cancer Chemother Pharmacol 2009, 63(6):983-995. 10.1007/s00280-008-0823-6, 18766340.
-
(2009)
Cancer Chemother Pharmacol
, vol.63
, Issue.6
, pp. 983-995
-
-
Sen, M.1
Tosca, P.J.2
Zwayer, C.3
Ryan, M.J.4
Johnson, J.D.5
Knostman, K.A.6
Giclas, P.C.7
Peggins, J.O.8
Tomaszewski, J.E.9
McMurray, T.P.10
-
68
-
-
63249092765
-
Persistently activated Stat3 maintains constitutive NF-kappaB activity in tumors
-
10.1016/j.ccr.2009.02.015, 2777654, 19345327
-
Lee H, Herrmann A, Deng JH, Kujawski M, Niu G, Li Z, Forman S, Jove R, Pardoll DM, Yu H. Persistently activated Stat3 maintains constitutive NF-kappaB activity in tumors. Cancer Cell 2009, 15(4):283-293. 10.1016/j.ccr.2009.02.015, 2777654, 19345327.
-
(2009)
Cancer Cell
, vol.15
, Issue.4
, pp. 283-293
-
-
Lee, H.1
Herrmann, A.2
Deng, J.H.3
Kujawski, M.4
Niu, G.5
Li, Z.6
Forman, S.7
Jove, R.8
Pardoll, D.M.9
Yu, H.10
|