Bioactivity evaluation of eclipta prostrata linn: A potential vasorelaxant

European Journal of Scientific Research

Volumn 44, Issue 2, 2010, Pages 167-176

  Prachayasittikul, Supaluk ^a   Wongsawatkul, Orapin ^b   Suksrichavalit, Thummaruk ^c   Ruchirawat, Somsak ^d   Prachayasittikul, Virapong ^c  

^a SRINAKHARINWIROT UNIVERSITY   (Thailand)

^b Faculty of Medicine Srinakharinwirot University   (Thailand)

^c MAHIDOL UNIVERSITY   (Thailand)

^d CHULABHORN RESEARCH INSTITUTE   (Thailand)

Author keywords

Antimicrobials; Antioxidants; Cytotoxic effect; Eclipta prostrata Linn; Nitric oxide; Thoracic aorta; Vasorelaxation

Indexed keywords

EID: 79953832742     PISSN: 1450216X     EISSN: 1450202X     Source Type: Journal    
DOI: None     Document Type: Article

References (33)

1. Arunachalam, G., N., Subramanian, G.P., Pazhani, V., Ravichandran, 2009. "Antiinflammatory activity of methanolic extract of Eclipta prostrata L (Astearaceae)." African Journal of Pharmacy and Pharmacology 3, pp. 97-100.
2. Bhaskar Rao, D., C.R., Kiran, Y., Madhavi, P., Koteswara Rao, T., Raghava Rao, 2009. "Evaluation of antioxidant potential of Clitoria ternata L. and Eclipta prostrata L." Indian Journal of Biochemistry & Biophysics 46, pp. 247-252.
3. Busarakumtragul, P., P., Tep-areenan, S., Chainakul, O., Wongsawatkul, 2010. "Effects of barakol on vascular functions in rats." International Journal of Pharmacology 6, pp. 257-263.
4. Chang, K.M., and G.H., Kim, 2009. "Constituents of the essential oil from Eclipta prostrata L." Journal of Food Science and Nutrition 14, pp. 168-171.
5. Demirci, B., P.P., McKeown, U., Bayraktutan DVM, 2008. "The bimodal regulation of vascular function by superoxide anion: role of endothelium." Biochemistry and Molecular Biology Reports 41, pp. 223-229. (Pubitemid 351518995)
6. Karthikumar, S., K., Vigneswari, K., Jegatheesan, 2007. "Screening of antibacterial and antioxidant activities of leaves of Eclipta prostrata (L)." Scientific Research and Essays 2, pp. 101-104.
7. Khanna, V.G., and K., Kannabiran, 2008. "Antimicrobial activity of saponin fractions of the leaves of Gymnema sylvestre and Eclipta prostrata." World Journal of Microbiology and Biotechnology 24, pp. 2737-2740.
8. Kim, D.I., S.H., Lee, J.H., Choi, H.S., Lillehoj, M.H., Yu, G.S., Lee, 2008. "The butanol fraction of Eclipta prostrata (Linn) effectively reduces serum lipid levels and improves antioxidant activities in CD rats." Nutrition Researches 28, pp. 550-554. (Pubitemid 352014870)
9. Kriengsak, L., K., Jan-Peter, C., Daranee, S., Chantragan, S., Rudee, S.A., Monnipha, B., Ahnond, D., Gerd, S., Jisnuson, 2008. "Juice of Eclipta prostrata inhibits cell migration in vitro and exhibits anti-angiogenic activity in vivo." In vivo 22, pp. 363-368.
10. Lee, M.K., N.R., Ha, H., Yang, S.H., Sung, G.H., Kim, Y.C., Kim, 2008. "Antiproliferative activity of triterpenoids from Eclipta prostrata on hepatic stellate cells." Phytomedicine 15, pp. 775-780.
11. Lin, X.H., Y.B., Wu, S., Lin, J.W., Zeng, P.Y., Zeng, J.Z., Wu, 2010. "Effects of volatile components and ethanolic extract from Eclipta prostrata on proliferation and differentiation of primary osteoblasts." Molecules 15, pp. 241-250.
12. Melo, P.A., M.C.D., Nascimento, W.B., Mors, G., Suarez-Kurtz, 1994. "Inhibition of the myotoxic and hemorrhagic activities of crotalid venoms by Eclipta prostrata (Asteraceae) extracts and constituents" Toxicon 32, pp. 595-603. (Pubitemid 24162717)
13. Mors, W.B., M.C.D., Nascimento, J., Parente, M.H., Silva, P.A., Melo, G., Suarez-Kurtz, 1989. "Neutralization of lethal and myotoxic activities of South American rattlesnake venom by extracts and constituents of the plant Eclipta prostrata (Asteraceae)." Toxicon 27, pp. 1003- 1009. (Pubitemid 19226954)
14. Ogunbinu A.O., G., Flamini, P.L., Cioni, I.A., Ogunwande, S.O., Okeniyi, 2009. "Essential oil constituents of Eclipta prostrata (L.) L. and Vernonia amygdalina Delile." Natural Product Communications 4, pp. 421-424.
15. Pithayanukul, P., B., Lapett, R., Bavovada, N., Pakmanee, R., Suttisri, 2007. "Inhibition of proteolytic and hemorrhagic activities by ethyl acetate extract of Eclipta prostrata against Malayan pit viper venom." Pharmaceutical Biology 45, pp. 282-288. (Pubitemid 47024403)
16. Pithayanukul, P., S., Laovachirasuwan, R., Bavovada, N., Pakmanee, R., Suttisri, 2004. "Antivenom potential of butanolic extract of Eclipta prostrata against Malayan pit viper venom." Journal of Ethnopharmacology 90, pp. 347-352. (Pubitemid 38180486)
17. Prachayasittikul, S., P., Buraparuangsang, A., Worachartcheewan, C., Isarankura-Na-Ayudhya, S., Ruchirawat, V., Prachayasittikul, 2008. "Antimicrobial and antioxidative activities of bioactive constituents from Hydnophytum formicarum Jack." Molecules 13, pp. 904-921.
18. Prachayasittikul, S., A., Worachartcheewan, R., Lawung, S., Ruchirawat, V., Prachayasittikul, 2009a. "Activities of thiotetrahydropyridines as antioxidant and antimicrobial agents." EXCLI Journal 8, pp. 107-114.
19. Prachayasittikul, S., K., Buttrawong, A., Worachartcheewan, S., Ruchirawat, V., Prachayasittikul, 2009b. "Isolation of bioactive metabolites from root extracts of Polyalthia debilis." European Journal of Scientific Research 38, pp. 596-603.
20. Prachayasittikul, S., P., Limnusont, R., Pingaew, S., Ruchirawat, V., Prachayasittikul, 2009c. "β-(1-Adamantylthio)pyridine analogs as antimicrobials and antimalarials." EXCLI Journal 8, pp. 35-40.
21. Prachayasittikul, S., S., Suphapong, A., Worachartcheewan, R., Lawung, S., Ruchirawat, V., Prachayasittikul, 2009d. "Bioactive metabolites from Spilanthes acmella Murr." Molecules 14, pp. 850-867.
22. Prachayasittikul, S., O., Wongsawatkul, A., Worachartcheewan, C., Nantasenamat, S., Ruchirawat V., Prachayasittikul, 2010a. "Elucidating the structure-activity relationships of the vasorelaxation and antioxidation properties of thionicotinic acid derivatives." Molecules 15, pp. 198-214.
23. Prachayasittikul, S., O., Wongsawatkul, A., Worachartcheewan, S., Ruchirawat, V., Prachayasittikul, 2010b. "Vasorelaxation and superoxide scavenging activities of orotic acid." International Journal of Pharmacology 6, pp. 375-380.
24. Rodríguez-Rodríguez, R., M.D., Herrera, J.S., Perona, V., Ruiz-Gutiérrez, 2004. "Potential vasorelaxant effects of oleanolic acid and erythrodiol two triterpenoids contained in 'orujo' olive oil on rat aorta." British Journal of Nutrition 92, pp. 635-642. (Pubitemid 39409557)
25. Samy, R.P., M.M., Thwin, P., Gopalakrishnakone, S., Ignacimuthu, 2008. "Ethnobotanical survey of folk plants for the treatment of snake bites in Southern part of Tamilnadu, India." Journal of Ethnopharmacology 115, pp. 302-312. (Pubitemid 350266274)
26. Shin, J.I., Y.K., Lee, Y.M., Kim, J.T., Hwang, O.J., Park, 2007. "Possible link between NO concentrations and COX-2 expression in systems treated with soy-isoflavones." Annals of the New York Academy of Sciences 1095, pp. 564-573.
27. Smitinund, T., 2001. "Thai plant names, Prachachon, Bangkok." p. 212.
28. Tewtrakul, S., S., Subhadhirasakul, S., Cheenpracha, C., Karalai, 2007. "HIV-1 protease and HIV-1 integrase inhibitory substances from Eclipta prostrata." Phytotherapy Researches 21, pp. 1092-1095. (Pubitemid 350190308)
29. Tengchaisri T., R., Chawengkirttikul, N., Rachaphaew, V., Reutrakul, R., Sangsuwan, S., Sirisinha, 1998. "Antitumor activity of triptolide against cholangiocarcinoma growth in vitro and in hamsters." Cancer Letters 133, pp. 169-175. (Pubitemid 29069041)
30. Wiart, C., S., Mogana, S., Khalifah, M., Mahan, S., Ismail, M., Buckle, A.K., Narayana, M., Sulaiman, 2004. "Antimicrobial screening of plants used for traditional medicine in the state of Perak, Peninsular Malaysia." Fitoterapia 75, pp. 68-73. (Pubitemid 38010407)
31. Wongsawatkul, O., S., Prachayasittikul, C., Isarankura-Na-Ayudhya, J., Satayavivad, S., Ruchirawat, V., Prachayasittikul, 2008. "Vasorelaxant and antioxidant activities of Spilanthes acmella Murr." International Journal of Molecular Sciences 9, pp. 2724-2744.
32. + channels to acetylcholine-induced dilatation of rat conduit and resistance arteries." Clinical and Experimental Pharmacology and Physiology 27, pp. 34-40. (Pubitemid 30104088)
33. Zenebe, W., O., Pechánová, R., Andriantsitohaina, 2003. "Red wine polyphenols induce vasorelaxation by increased nitric oxide bioactivity." Physiological Research 52, pp. 425-432. (Pubitemid 37039906)