Juice of Eclipta prostrata inhibits cell migration in vitro and exhibits anti-angiogenic activity in vivo

In Vivo

Volumn 22, Issue 3, 2008, Pages 363-368

  Lirdprapamongkol, Kriengsak ^a,b   Kramb, Jan Peter ^c   Chokchaichamnankit, Daranee ^a   Srisomsap, Chantragan ^a   Surarit, Rudee ^a,b   Sila Asna, Monnipha ^d   Bunyaratvej, Ahnond ^d   Danhardt, Gerd ^c   Svasti, Jisnuson ^a,b  

^a Krung Thep Maha Nakhon   (Thailand)

^b Mahidol Uiversity ^*  (Thailand)

^c JOHANNES GUTENBERG UNIVERSITY   (Germany)

^d MAHIDOL UNIVERSITY   (Thailand)

Author keywords

Anti angiogenic; Anti metastatic; Cell migration; Medicinal plants

Indexed keywords

ANGIOGENESIS INHIBITOR; ECLIPTA PROSTRATA EXTRACT; METHANOL; WATER;

ANIMAL TISSUE; ANTIANGIOGENIC ACTIVITY; ARTICLE; CELL ADHESION; CELL INVASION; CELL MIGRATION; CHICK EMBRYO; CHORIOALLANTOIS; CONCENTRATION RESPONSE; CONTROLLED STUDY; CYTOTOXICITY; EMBRYO; HUMAN; HUMAN CELL; IC 50; IN VITRO STUDY; METASTASIS INHIBITION; NONHUMAN; SOLVENT EXTRACTION;

EID: 45949087186     PISSN: 0258851X     EISSN: None     Source Type: Journal    
DOI: None     Document Type: Article

References (18)

1. Price JT and Thompson EW: Mechanisms of tumour invasion and metastasis: emerging targets for therapy. Expert Opin Ther Targets 6: 217-233, 2002.
2. Kohn EC and Liotta LA: Molecular insights into cancet invasion: strategies for prevention and intervention. Cancer Res 55: 1856-1862, 1995.
3. Folkman J: What is the evidence that tumors are angiogenesis dependent? J Natl Cancer Inst 82: 4-6, 1990.
4. Bunyapraphatsara N and Chokchaijaroenporn A: Medicinal Plants Indigenous to Thailand. Vol. 1. Bangkok, Medicinal Plant Information Center, Faculty of Pharmaceutical Sciences, Mahidol University. pp. 154-159, 1996.
5. Chuakul W, Saralamp P, Paonil W, Temsiririrkkul R and Clayton T: Medicinal Plants in Thailand. Vol.2. Bangkok, Amarin Printing and Publishing Public. p 107, 1997.
6. Kobori M, Yang Z, Gong D, Heissmeyer V, Zhu H, Jung YK, Angelica M Gakidis M, Rao A, Sekine T, Ikegami F, Yuan C and Yaun J: Wedelolactone suppresses LPS-induced caspase-11 expression by directly inhibiting the IKK complex. Cell Death Differ 11: 123-130, 2004.
7. Tewtrakul S, Subhadhirasakul S, Cheenpracha S and Karalai C: HIV-1 protease and HIV-1 integrase inhibitory substances from Eclipta prostrata. Phytother Res 21: 1092-1095, 2007.
8. Lirdprapamongkol K, Mahidol C, Thongnest S, Prawat H, Ruchirawat S, Srisomsap C, Surarit R, Punyarit P and Svasti J: Anti-metastatic effects of aqueous extract of Helixanthera parasitica. J Ethnopharmacol 86: 253-256, 2003.
9. Rust WL, Huff JL and Plopper GE: Screening assay for promigratory/ antimigratory compounds. Anal Biochem 280: 11-19, 2000.
10. Peifer C and Dannhardt G: A novel quantitative chick embryo assay as an angiogenesis model using digital image analysis. Anticancer Res 24: 1545-1552, 2004.
11. Ma-Ma K, Nyunt N and Tin KM: The protective effect of Eclipta alba on carbon tetrachloride-induced acute liver damage. Toxicol Appl Pharmacol 45: 723-728, 1978.
12. Jayathirtha MG and Mishra SH: Preliminary immunomodulatory activities of methanol extracts of Eclipta alba and Centella asiatica. Phytomedicine 11: 361-365, 2004.
13. Karthikumar S, Vigneswari K and Jegatheesan K: Screening of antibacterial and antioxidant activities of leaves of Eclipta prostrata (L). Sci Res Essay 2: 101-104, 2007.
14. Sawant M, Isaac JC and Narayanan S: Analgesic studies on total alkaloids and alcohol extracts of Eclipta alba (Linn.) Hassk. Phytother Res 18: 111-113, 2004.
15. Kumari CS, Govindasamy S and Sukumar E: Lipid lowering activity of Eclipta prostrata in experimental hyperlipidemia. J Ethnopharmacol 105: 332-335, 2006.
16. Thakur VD and Mengi SA: Neuropharmacological profile of Eclipta alba (Linn.) Hassk. J Ethnopharmacol 102: 23-31, 2005.
17. Anand-Apte B and Zetter B: Signaling mechanisms in growth factors-stimulated cell motility. Stem Cells 15: 259-267, 1997.
18. Heo JC, Park JY, Lee JM, Kwon TK, Kim SU, Chung SK and Lee SH: Wisteria floribunda gall extract inhibits cell migration in mouse B16F1 melanoma cells by regulating CD44 expression and GTP-RhoA activity. J Ethnopharmacol 102: 10-14, 2005.