Control of the stereo-selectivity of styrene epoxidation by cytochrome P450 BM3 using structure-based mutagenesis

Metallomics

Volumn 3, Issue 4, 2011, Pages 410-416

  Huang, Wei Cheng ^a   Cullis, Paul M ^a   Raven, Emma Lloyd ^a   Roberts, Gordon C K ^a  

^a UNIVERSITY OF LEICESTER   (United Kingdom)

Author keywords

[No Author keywords available]

Indexed keywords

ACTIVE SITE; BACILLUS MEGATERIUM; BIOCATALYSIS; BIOTECHNOLOGICAL APPLICATIONS; CYTOCHROME P450 BM3; FLAVOCYTOCHROME P450 BM3; HYDROPHOBIC POCKETS; LAURATE; RATIONAL DESIGN; SMALL MOLECULES; STRUCTURE-BASED; STYRENE EPOXIDATIONS;

BACTERIOLOGY; CATALYST ACTIVITY; OXYGENATION; STRUCTURAL ANALYSIS;

STYRENE;

CYTOCHROME P450 BM3; LAURIC ACID; STYRENE;

AMINO ACID SUBSTITUTION; ARTICLE; BACILLUS MEGATERIUM; ENZYME ACTIVITY; ENZYME BINDING; ENZYME SPECIFICITY; ENZYME STRUCTURE; ENZYME SUBSTRATE; EPOXIDATION; MUTAGENESIS; NONHUMAN; PRIORITY JOURNAL; STEREOCHEMISTRY;

BACILLUS MEGATERIUM; BACTERIAL PROTEINS; CYTOCHROME P-450 ENZYME SYSTEM; EPOXY COMPOUNDS; INDUSTRIAL MICROBIOLOGY; MODELS, MOLECULAR; MUTAGENESIS, SITE-DIRECTED; MUTANT PROTEINS; MUTATION; NADPH-FERRIHEMOPROTEIN REDUCTASE; PROTEIN BINDING; PROTEIN CONFORMATION; STYRENE;

BACILLUS MEGATERIUM;

EID: 79953795900     PISSN: 17565901     EISSN: 1756591X     Source Type: Journal    
DOI: 10.1039/c0mt00082e     Document Type: Article

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