A model for human cytochrome P450 2D6 based on homology modeling and NMR studies of substrate binding

Biochemistry

Volumn 35, Issue 14, 1996, Pages 4540-4550

  Modi, S ^a   Paine, M J ^b   Sutcliffe, M J ^a   Lian, L Y ^a   Primrose, W U ^a   Wolf, C R ^b   Roberts, G C K ^a  

^a UNIVERSITY OF LEICESTER   (United Kingdom)

^b UNIVERSITY OF DUNDEE   (United Kingdom)

Author keywords

[No Author keywords available]

Indexed keywords

CYTOCHROME P450;

ARTICLE; BINDING AFFINITY; CRYSTAL STRUCTURE; DEMETHYLATION; ENZYME BINDING; ENZYME SUBSTRATE; NONHUMAN; NUCLEAR MAGNETIC RESONANCE; OXYGENATION; PRIORITY JOURNAL; PROTEIN PROTEIN INTERACTION; PROTEIN PURIFICATION; SEQUENCE HOMOLOGY; XENOBIOTIC METABOLISM;

AMINO ACID SEQUENCE; ANIMALS; BACULOVIRIDAE; BASE SEQUENCE; BINDING SITES; CELL LINE; CYTOCHROME P-450 CYP2D6; CYTOCHROME P-450 ENZYME SYSTEM; DNA PRIMERS; DNA, COMPLEMENTARY; HEME; HUMANS; MAGNETIC RESONANCE SPECTROSCOPY; MIXED FUNCTION OXYGENASES; MODELS, MOLECULAR; MOLECULAR SEQUENCE DATA; MOLECULAR STRUCTURE; RECOMBINANT PROTEINS; SEQUENCE HOMOLOGY, AMINO ACID; SPECTROPHOTOMETRY; SPODOPTERA; SUBSTRATE SPECIFICITY;

EID: 0029914807     PISSN: 00062960     EISSN: None     Source Type: Journal    
DOI: 10.1021/bi952742o     Document Type: Article

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