An endogenous inhibitor of nitric oxide synthase regulates endothelial adhesiveness for monocytes

Journal of the American College of Cardiology

Volumn 36, Issue 7, 2000, Pages 2287-2295

  Böger, Rainer H ^a   Bode Böger, Stefanie M ^a   Tsao, Philip S ^a   Lin, Patrick S ^a   Chan, Jason R ^a   Cooke, John P ^a  

^a STANFORD UNIVERSITY SCHOOL OF MEDICINE   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

ARGININE; ARGININE DERIVATIVE; IMMUNOGLOBULIN ENHANCER BINDING PROTEIN; MONOCLONAL ANTIBODY; MONOCYTE CHEMOTACTIC PROTEIN 1; NITRIC OXIDE; NITRIC OXIDE SYNTHASE INHIBITOR; SUPEROXIDE;

ARTICLE; ATHEROSCLEROSIS; CELL ADHESION; CONCENTRATION RESPONSE; CONTROLLED STUDY; ENDOTHELIUM CELL; HUMAN; HUMAN CELL; HYPERCHOLESTEROLEMIA; MONOCYTE; OXIDATIVE STRESS; PRIORITY JOURNAL; REGULATORY MECHANISM; SIGNAL TRANSDUCTION;

ARGININE; CELL ADHESION; CELLS, CULTURED; CHEMOKINE CCL2; ENDOTHELIUM, VASCULAR; HUMANS; MONOCYTES; NITRIC OXIDE SYNTHASE; OXIDATIVE STRESS;

EID: 0033667562     PISSN: 07351097     EISSN: None     Source Type: Journal    
DOI: 10.1016/S0735-1097(00)01013-5     Document Type: Article

References (54)

1. Impaired vasodilation of forearm resistance vessels in hypercholesterolemic humans
2. L-arginine attenuates platelet reactivity in hypercholesterolemic rabbits
3. Adhesiveness of mononuclear cells in hypercholesterolemic humans is normalized by dietary L-arginine
4. The L-arginine-nitric oxide pathway: Role in atherosclerosis and therapeutic implications
5. Nitric oxide synthase: Role in the genesis of vascular disease
6. Arginine restores cholinergic relaxation of hypercholesterolemic rabbit thoracic aorta
7. Correction of endothelial dysfunction in coronary microcirculation of hypercholesterolemic patients by L-arginine
8. L-arginine improves endothelium-dependent vasodilation in hypercholesterolemic humans
9. Long-term L-arginine supplementation improves small-vessel coronary endothelial function in humans
10. Endogenous dimethylarginine as an inhibitor of nitric oxide synthesis
11. Synthesis of N(G), N(G) dimethylarginine by human endothelial cells
12. Increase of an endogenous inhibitor of nitric oxide synthesis in serum of high cholesterol fed rabbits
13. Elevated L-arginine/dimethylarginine ratio contributes to enhanced systemic NO production by dietary L-arginine in hypercholesterolemic rabbits
14. Biochemical evidence for impaired nitric oxide synthesis in patients with peripheral arterial occlusive disease
15. Asymmetric dimethylarginine (ADMA): A novel risk factor for endothelial dysfunction: Its role in hypercholesterolemia
16. Consequences of hyperhomocyst(e)inemia on vascular function in atherosclerotic monkeys
17. Endogenous nitric oxide synthase inhibitor: A novel marker of atherosclerosis
18. Antiatherosclerotic effects of L-arginine in the hypercholesterolemic rabbit
19. Dietary arginine prevents atherogenesis in the coronary artery of the hypercholesterolemic rabbit
20. Supplementation of hypercholesterolemic rabbits with L-arginine reduces the vascular release of superoxide anions and restores NO production
21. Dietary L-arginine reduces the progression of atherosclerosis in cholesterol-fed rabbits - Comparison with lovastatin
22. Regression or progression: Dependency on vascular nitric oxide
23. Enhanced endothelial adhesiveness in hypercholesterolemia is attenuated by L-arginine
24. Chronic inhibition of nitric oxide production accelerates neointima formation and impairs endothelial function in hypercholesterolemic rabbits
25. Long-term inhibition of NO synthesis promotes atherosclerosis in the hypercholesterolemic rabbit thoracic aorta
26. L-arginine prevents xanthoma development and inhibits atherosclerosis in LDL receptor knockout mice
27. Exposure to shear stress alters endothelial adhesiveness: Role of nitric oxide
28. Intracellular oxidative stress induced by nitric oxide synthesis inhibition increases endothelial cell adhesion to neutrophils
29. Transcriptional regulation of endothelial cell adhesion molecules: NF-κB and cytokine-inducible enhancers
30. Vascular cell adhesion molecule-1 gene transcription and expression are regulated through an antioxidant-sensitive mechanism in human vascular endothelial cells
31. NF-κB and Sp1 regulate transcription of the human monocyte chemoattractant protein-1 gene
32. Fluid flow inhibits endothelial adhesiveness. Nitric oxide and transcriptional regulation of VCAM-1
33. Nitric oxide regulates monocyte chemotactic protein-1
34. Spontaneous transformation and immortalization of human endothelial cells
35. Rare spontaneously transformed human endothelial cell line provides a useful new research tool
36. Native low-density lipoprotein increases endothelial cell nitric oxide synthase generation of superoxide anion
37. Protein measured with the folin phenol reagent
38. Oral L-arginine inhibits platelet aggregation but does not enhance endothelium-dependent dilation in healthy young men
39. Dietary L-arginine supplementation normalizes platelet aggregation in hypercholesterolemic humans
40. L-arginine reduces human monocyte adhesion to vascular endothelium and endothelial expression of cell adhesion molecules
41. Purification and characterization of particulate endothelium-derived relaxing factor synthase from cultured and native bovine aortic endothelial cells
42. L-arginine plasma concentrations in hypercholesterolemia
43. Effects of an endogenous inhibitor of nitric oxide synthesis on postcapillary venules
44. Response of cerebral blood vessels to an endogenous inhibitor of nitric oxide synthase
45. Studies on the catabolilsm of N(G)-methylarginine, N(G), N(G)-dimethylarginine and N(G), N(G')-dimethylarginine in the rabbit
46. Regulation of nitric oxide synthesis by dimethylarginine dimethylaminohydrolase
47. Structural specificity of substrate for S-adenosylmethionine:protein arginine N-methyltransferases
48. Metabolism of methylarginines by human vasculature: Implications for the regulation of nitric oxide synthesis
49. A novel mechanism for endothelial dysfunction: Dysregulation of dimethylarginine dimethylaminohydrolase
50. Multiple receptors on human monocytes are involved in adhesion to cultured human endothelial cells
51. Endothelial expression of a mononuclear leukocyte adhesion molecule during atherogenesis
52. Expression of monocyte chemoattractant protein 1 in macrophage-rich areas of human and rabbit atherosclerotic lesions
53. Nitric oxide modulates the expression of monocyte chemoattractant protein-1 in cultured human endothelial cells
54. Induction and stabilization of I kappa B alpha by nitric oxide mediates inhibition of NF-kappa B