Platelet protein kinase C-θ deficiency with human RUNX1 mutation: PRKCQ is a transcriptional target of RUNX1

Arteriosclerosis, Thrombosis, and Vascular Biology

Volumn 31, Issue 4, 2011, Pages 921-927

  Jalagadugula, Gauthami ^a   Mao, Guangfen ^a   Kaur, Gurpreet ^a   Dhanasekaran, Danny N ^a   Rao, A Koneti ^a  

^a TEMPLE UNIVERSITY SCHOOL OF MEDICINE   (United States)

Author keywords

megakaryocytes; PKC ; Platelets; PRKCQ; RUNX1; transcriptional regulation

Indexed keywords

PLECKSTRIN; PROTEIN KINASE C THETA; SMALL INTERFERING RNA; TRANSCRIPTION FACTOR RUNX1;

ADULT; ARTICLE; CHROMATIN IMMUNOPRECIPITATION; CONTROLLED STUDY; DOWN REGULATION; ENZYME DEFICIENCY; GENE SILENCING; HUMAN; HUMAN CELL; IN VIVO STUDY; MALE; MEGAKARYOCYTE; PRIORITY JOURNAL; PROMOTER REGION; PROTEIN BINDING; PROTEIN EXPRESSION; PROTEIN PHOSPHORYLATION; THROMBOCYTE AGGREGATION; THROMBOCYTOPENIA;

BINDING SITES; BLOOD PLATELETS; CELL LINE, TUMOR; CHROMATIN IMMUNOPRECIPITATION; CONSENSUS SEQUENCE; CORE BINDING FACTOR ALPHA 2 SUBUNIT; ELECTROPHORETIC MOBILITY SHIFT ASSAY; GENE EXPRESSION REGULATION, ENZYMOLOGIC; GENES, REPORTER; HUMANS; ISOENZYMES; MALE; MEGAKARYOCYTES; MUTATION; PROMOTER REGIONS, GENETIC; PROTEIN KINASE C; RECOMBINANT PROTEINS; RNA INTERFERENCE; THROMBOCYTOPENIA; TRANSCRIPTION, GENETIC; TRANSFECTION; YOUNG ADULT;

EID: 79953738438     PISSN: 10795642     EISSN: None     Source Type: Journal    
DOI: 10.1161/ATVBAHA.110.221879     Document Type: Article

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