Silencing tissue inhibitors of metalloproteinases (TIMPs) with short interfering RNA reveals a role for TIMP-1 in hepatic stellate cell proliferation

Biochemical and Biophysical Research Communications

Volumn 407, Issue 2, 2011, Pages 277-282

  Fowell, Andrew J ^a   Collins, Jane E ^a   Duncombe, Dale R ^a   Pickering, Judith A ^a   Rosenberg, William M C ^b   Benyon, R Christopher ^a  

^a UNIVERSITY OF SOUTHAMPTON   (United Kingdom)

^b UNIVERSITY COLLEGE LONDON   (United Kingdom)

Author keywords

Akt; Liver fibrosis; RNA interference

Indexed keywords

MITOGEN ACTIVATED PROTEIN KINASE 1; MITOGEN ACTIVATED PROTEIN KINASE 3; PROTEIN KINASE B; RECOMBINANT PROTEIN; SMALL INTERFERING RNA; TISSUE INHIBITOR OF METALLOPROTEINASE; TISSUE INHIBITOR OF METALLOPROTEINASE 1; TISSUE INHIBITOR OF METALLOPROTEINASE 2;

ANIMAL CELL; APOPTOSIS; ARTICLE; AUTOCRINE EFFECT; CELL ACTIVATION; CELL NUCLEUS; CELL PROLIFERATION; CELL TYPE; CONTROLLED STUDY; CYTOPLASM; ENZYME PHOSPHORYLATION; LIVER FIBROSIS; MALE; MITOGENESIS; MOUSE; MYOFIBROBLAST; NONHUMAN; PRIORITY JOURNAL; RAT; STELLATE CELL;

ANIMALS; CELL PROLIFERATION; CELLS, CULTURED; GENE SILENCING; HEPATIC STELLATE CELLS; LIVER CIRRHOSIS; MALE; MICE; MICE, KNOCKOUT; RATS; RATS, SPRAGUE-DAWLEY; RNA, SMALL INTERFERING; TISSUE INHIBITOR OF METALLOPROTEINASE-2; TISSUE INHIBITOR OF METALLOPROTEINASE-3;

EID: 79953685584     PISSN: 0006291X     EISSN: 10902104     Source Type: Journal    
DOI: 10.1016/j.bbrc.2011.02.009     Document Type: Article

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