A novel intermediate in the reaction of seleno CYP119 with m -chloroperbenzoic acid

Biochemistry

Volumn 50, Issue 14, 2011, Pages 3014-3024

  Sivaramakrishnan, Santhosh ^a   Ouellet, Hugues ^a   Du, Jing ^b   McLean, Kirsty J ^c   Medzihradszky, Katalin F ^a   Dawson, John H ^b   Munro, Andrew W ^c   Ortiz De Montellano, Paul R ^a  

^a UNIVERSITY OF CALIFORNIA   (United States)

^b UNIVERSITY OF SOUTH CAROLINA   (United States)

^c UNIVERSITY OF MANCHESTER   (United Kingdom)

Author keywords

[No Author keywords available]

Indexed keywords

ABSORBANCES; ACTIVE SITE; ACTIVE SITE STRUCTURE; CATALYTIC CYCLES; CATALYTIC PROPERTIES; COMPOUND I; CRITICAL DETERMINANT; CYTOCHROME P450; M-CHLOROPERBENZOIC ACID; MONOOXYGENATION; NOVEL INTERMEDIATES; OXIDATIVE DAMAGE; OXIDATIVE MODIFICATION; REACTIVE SPECIES; STABLE SPECIES; THIOLATE LIGANDS;

AMINO ACIDS; PORPHYRINS; REACTION INTERMEDIATES; REDUCING AGENTS;

LIGANDS;

3 CHLOROPERBENZOIC ACID; ANION; CYTOCHROME P450; CYTOCHROME P450 119; HEME; LIGAND; SELENIUM DERIVATIVE; SELENO PROTEIN; SELENOLATE; THIOL DERIVATIVE; UNCLASSIFIED DRUG;

ARTICLE; CATALYSIS; CHEMICAL REACTION; CONTROLLED STUDY; ELECTRON; OXIDATIVE STRESS; PRIORITY JOURNAL; PROTEIN STRUCTURE; STOICHIOMETRY; THERMOPHILE; THERMOSTABILITY;

ARCHAEAL PROTEINS; CHLOROBENZOATES; CYTOCHROME P-450 ENZYME SYSTEM; FERRIC COMPOUNDS; FERROUS COMPOUNDS; KINETICS; OXIDATION-REDUCTION; SELENOCYSTEINE; SPECTROMETRY, MASS, ELECTROSPRAY IONIZATION; SPECTROPHOTOMETRY;

EID: 79953683449     PISSN: 00062960     EISSN: 15204995     Source Type: Journal    
DOI: 10.1021/bi101728y     Document Type: Article

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