Tyrosine radical formation in the reaction of wild type and mutant cytochrome P450cam with peroxy acids: A multifrequency EPR study of intermediates on the millisecond time scale

Journal of Biological Chemistry

Volumn 279, Issue 12, 2004, Pages 10919-10930

  Schünemann, Volker ^a   Lendzian, Friedhelm ^b   Jung, Christiane ^c   Contzen, Jörg ^c   Barra, Anne Laure ^d   Sligar, Stephen G ^e   Trautwein, Alfred X ^a  

^a UNIVERSITY OF LÜBECK   (Germany)

^b TECHNISCHE UNIVERSITÄT BERLIN   (Germany)

^c MAX DELBRÜCK CENTER FOR MOLECULAR MEDICINE   (Germany)

^d CNRS   (France)

^e UNIVERSITY OF ILLINOIS AT URBANA CHAMPAIGN   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

COMPUTER SIMULATION; MICROWAVES; PARAMAGNETIC RESONANCE; PROTEINS;

ELECTRON TRANSFER; FREEZE-QUENCHED INTERMEDIATES;

AMINO ACIDS;

CATION; CYTOCHROME P450; CYTOCHROME P450 101; PEROXIDE; PHENYLALANINE; PORPHYRIN; RADICAL; TYROSINE; UNCLASSIFIED DRUG;

AMINO ACID SUBSTITUTION; ARTICLE; CONTROLLED STUDY; ELECTRON SPIN RESONANCE; ELECTRON TRANSPORT; FREQUENCY MODULATION; MICROWAVE RADIATION; MOLECULAR DYNAMICS; NONHUMAN; PRIORITY JOURNAL; REACTION ANALYSIS;

BASE SEQUENCE; CAMPHOR 5-MONOOXYGENASE; DNA PRIMERS; ELECTRON SPIN RESONANCE SPECTROSCOPY; FREE RADICALS; MUTATION; PEROXIDES; TYROSINE;

EID: 1642483708     PISSN: 00219258     EISSN: None     Source Type: Journal    
DOI: 10.1074/jbc.M307884200     Document Type: Article

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