메뉴 건너뛰기




Volumn 12, Issue 4, 2011, Pages 372-382

An electrochemical outlook on tamoxifen biotransformation: Current and future prospects

Author keywords

Biotransformation; Breast cancer; DNA; Electrochemistry; Sensor; Tamoxifen

Indexed keywords

ANTIESTROGEN; CYTOCHROME P450 2D6; DRUG METABOLITE; GLUTATHIONE; LIPID; PIPENDOXIFENE; TAMOXIFEN;

EID: 79953669463     PISSN: 13892002     EISSN: None     Source Type: Journal    
DOI: 10.2174/138920011795202965     Document Type: Article
Times cited : (13)

References (76)
  • 2
    • 34248350428 scopus 로고    scopus 로고
    • Medicinal chemistry and emerging strategies applied to the development of selective estrogen receptor modulators (SERMs)
    • DOI 10.2174/092986707780598023
    • Musa, M.A.; Khan, M.O.F.; Cooperwood, J.S. Medicinal chemistry and emerging strategies applied to the development of selective estrogen receptor modulators (SERMs). Curr. Med. Chem., 2007, 14, 1249-1261. (Pubitemid 46739325)
    • (2007) Current Medicinal Chemistry , vol.14 , Issue.11 , pp. 1249-1261
    • Musa, M.A.1    Khan, M.O.F.2    Cooperwood, J.S.3
  • 3
    • 0031056093 scopus 로고    scopus 로고
    • Efficacy of tamoxifen as treatment of breast cancer
    • Powles, T.J. Efficacy of tamoxifen as treatment of breast cancer. Semin. Oncol., 1997, 24 (Suppl. 1), 48-54.
    • (1997) Semin. Oncol. , vol.24 , Issue.SUPPL. 1 , pp. 48-54
    • Powles, T.J.1
  • 4
    • 0031778177 scopus 로고    scopus 로고
    • Basic guide to the mechanisms of antiestrogen action
    • MacGregor, J.I.; Jordan, V.C. Basic guide to the mechanisms of antiestrogen action. Pharmacol. Rev., 1998, 50 (2), 151-196 and references herein. (Pubitemid 28305723)
    • (1998) Pharmacological Reviews , vol.50 , Issue.2 , pp. 151-196
    • Macgregor, J.I.1    Jordan, V.C.2
  • 5
    • 33847292423 scopus 로고    scopus 로고
    • Tamoxifen: Important considerations of a multi-functional compound with organ-specific properties
    • DOI 10.1016/j.ctrv.2006.09.008, PII S030573720600185X
    • Singh, M.N.; Stringfellow, H.F.; Paraskevaidis, E.; Martin-Hirsch, P.L.; Martin, F.L. Tamoxifen: important considerations of a multifunctional compound with organ-specific properties. Cancer Treat. Rev., 2007, 33, 91-100. (Pubitemid 46323395)
    • (2007) Cancer Treatment Reviews , vol.33 , Issue.2 , pp. 91-100
    • Singh, M.N.1    Stringfellow, H.F.2    Paraskevaidis, E.3    Martin-Hirsch, P.L.4    Martin, F.L.5
  • 6
    • 0031717236 scopus 로고    scopus 로고
    • Tamoxifen - The treatment of choice. Why look for alternatives?
    • Baum, M. Tamoxifen -the treatment of choice. Why look for alternatives? Br. J. Cancer, 1998, 78 (Suppl. 4), 1-4.
    • (1998) Br. J. Cancer , vol.78 , Issue.SUPPL. 4 , pp. 1-4
    • Baum, M.1
  • 9
    • 0037464769 scopus 로고    scopus 로고
    • Overview of the main outcomes in breast-cancer prevention trials
    • DOI 10.1016/S0140-6736(03)12342-2
    • Cuzick, J.; Powles, T.; Veronesi, U.; Forbes, J.; Edwards, R.; Ashley, S.; Boyle, P. Overview of the main outcomes in breast-cancer prevention trials. Lancet, 2003, 361, 296-300. (Pubitemid 36126189)
    • (2003) Lancet , vol.361 , Issue.9354 , pp. 296-300
    • Cuzick, J.1    Powles, T.2    Veronesi, U.3    Forbes, J.4    Edwards, R.5    Ashley, S.6    Boyle, P.7
  • 11
    • 71949101735 scopus 로고    scopus 로고
    • Is tamoxifen a genotoxic carcinogen in women?
    • Brown, K. Is tamoxifen a genotoxic carcinogen in women? Mutagenesis, 2009, 24, 391-404.
    • (2009) Mutagenesis , vol.24 , pp. 391-404
    • Brown, K.1
  • 13
    • 0028835120 scopus 로고
    • Tamoxifen and toremifene lower serum cholesterol by inhibition of delta 8-cholestenol conversion to lathosterol in women with breast cancer
    • Gylling, H.; Pyrhonen, S.; Mantyla, E.; Maenpaa, H.; Kangas, L.; Miettinen, T. A. Tamoxifen and toremifene lower serum cholesterol by inhibition of delta 8-cholestenol conversion to lathosterol in women with breast cancer. J. Clin. Oncol., 1995, 13, 2900-2905.
    • (1995) J. Clin. Oncol. , vol.13 , pp. 2900-2905
    • Gylling, H.1    Pyrhonen, S.2    Mantyla, E.3    Maenpaa, H.4    Kangas, L.5    Miettinen, T.A.6
  • 14
    • 0029558791 scopus 로고
    • Drugs for osteoporosis prevention: Mechanisms of bone maintenance
    • Ruenitz, P.C. Drugs for osteoporosis prevention: mechanisms of bone maintenance. Curr. Med. Chem., 1995, 2, 791-802. (Pubitemid 26024163)
    • (1995) Current Medicinal Chemistry , vol.2 , Issue.4 , pp. 791-802
    • Ruenitz, P.C.1
  • 15
    • 36849020052 scopus 로고    scopus 로고
    • Tamoxifen resistance and epigenetic modifications in breast cancer cell lines
    • DOI 10.2174/092986707782794023
    • Badia, E.; Oliva, J.; Balaguer, P.; Cavailles, V. Tamoxifen resistance and epigenetic modifications in breast cancer cell lines. Curr. Med. Chem., 2007, 14, 3035-3043. (Pubitemid 350226972)
    • (2007) Current Medicinal Chemistry , vol.14 , Issue.28 , pp. 3035-3043
    • Badia, E.1    Oliva, J.2    Balaguer, P.3    Cavailles, V.4
  • 16
    • 0038147559 scopus 로고    scopus 로고
    • Tamoxifen: Is it safe? comparison of activation and detoxication mechanisms in rodents and in humans
    • DOI 10.2174/1389200033489451
    • White, I.N.H. Tamoxifen: is it safe? Comparison of activation and detoxication mechanisms in rodents and in humans. Curr. Drug Metab., 2003, 4, 223-239 and references herein. (Pubitemid 36656480)
    • (2003) Current Drug Metabolism , vol.4 , Issue.3 , pp. 223-239
    • White, I.N.H.1
  • 17
    • 4243063941 scopus 로고    scopus 로고
    • Comprehensive evaluation of tamoxifen sequential biotransformation by the human cytochrome P450 system in vitro: Prominent roles for CYP3A and CYP2D6
    • DOI 10.1124/jpet.104.065607
    • Desta, Z.; Ward, B.A.; Soukhova, N.V.; Flockhart, D.A. Comprehensive evaluation of tamoxifen sequential biotransformation by the human cytochrome P450 system in vitro: prominent roles for CYP3A and CYP2D6. J. Pharmacol. Exp. Ther., 2004, 310, 1062-1075. (Pubitemid 39108928)
    • (2004) Journal of Pharmacology and Experimental Therapeutics , vol.310 , Issue.3 , pp. 1062-1075
    • Desta, Z.1    Ward, B.A.2    Soukhova, N.V.3    Flockhart, D.A.4
  • 18
    • 27544464442 scopus 로고    scopus 로고
    • Formation of tamoxifen-DNA adducts via O-sulfonation, not O-acetylation, of α-hydroxytamoxifen in rat and human livers
    • DOI 10.1124/dmd.105.005330
    • Kim, S.Y.; Laxmi, Y.R.S.; Suzuki, N.; Ogura, K.; Watabe, T.; Duffel, M.W.; Shibutani, S. Formation of tamoxifen-DNA adducts via o-sulfonation, not o-acetylation, of a-hydroxytamoxifen in rat and human livers. Drug Metab. Dispos. (Pubitemid 41539966)
    • (2005) Drug Metabolism and Disposition , vol.33 , Issue.11 , pp. 1673-1678
    • Sung, Y.K.1    Santosh Laxmi, Y.R.2    Suzuki, N.3    Ogura, K.4    Watabe, T.5    Duffel, M.W.6    Shibutani, S.7
  • 20
    • 0033970909 scopus 로고    scopus 로고
    • Synthesis and reactivity of a potential carcinogenic metabolite of tamoxifen: 3,4-Dihydroxytamoxifen-o-quinone
    • DOI 10.1021/tx990145n
    • Zhang, F.; Fan, P.W.; Liu, X.; Shen, L.; van Breemen, R.B.; Bol-ton, J.L. Synthesis and reactivity of a potential carcinogenic metabolite of tamoxifen: 3,4-dihydroxytamoxifen-o-quinone. Chem. Res. Toxicol., 2000, 13, 53-62. (Pubitemid 30055959)
    • (2000) Chemical Research in Toxicology , vol.13 , Issue.1 , pp. 53-62
    • Zhang, F.1    Fan, P.W.2    Liu, X.3    Shen, L.4    Van Breemen, R.B.5    Bolton, J.L.6
  • 21
    • 0030008422 scopus 로고    scopus 로고
    • Conformational studies and electronic structures of tamoxifen and toremifene and their allylic carbocations proposed as reactive intermediates leading to DNA adduct formation
    • DOI 10.1021/jm960255g
    • Kuramochi, H. Conformational studies and electronic structures of tamoxifen and toremifene and their allylic carbocations proposed as reactive intermediates leading to DNA adduct formation. J. Med. Chem., 1996, 39, 2877-2886. (Pubitemid 26251025)
    • (1996) Journal of Medicinal Chemistry , vol.39 , Issue.15 , pp. 2877-2886
    • Kuramochi, H.1
  • 22
    • 0037350190 scopus 로고    scopus 로고
    • Quantification of tamoxifen DNA adducts using on-line sample preparation and HPLC-electrospray ionization tandem mass spectrometry
    • DOI 10.1021/tx020090g
    • Costa, G.G.; Marques, M.M.; Beland, F.A.; Freeman, J.P.; Churchwell, M.I.; Doerge, D.R. Quantification of tamoxifen DNA adducts using on-line sample preparation and HPLC-electrospray ionization tandem mass spectrometry. Chem. Res. Toxicol., 2003, 16, 357-366. (Pubitemid 36373700)
    • (2003) Chemical Research in Toxicology , vol.16 , Issue.3 , pp. 357-366
    • Da Costa, G.G.1    Marques, M.M.2    Beland, F.A.3    Freeman, J.P.4    Churchwell, M.I.5    Doerge, D.R.6
  • 24
    • 34748865637 scopus 로고    scopus 로고
    • Elimination of antiestrogenic effects of active tamoxifen metabolites by glucuronidation
    • DOI 10.1124/dmd.107.016279
    • Zheng, Y.; Sun, D.; Sharma, A.K.; Chen, G.; Amin, S.; Lazarus, P. Elimination of antiestrogenic effects of active tamoxifen metabolites by glucuronidation. Drug Metab. Dispos. (Pubitemid 47481590)
    • (2007) Drug Metabolism and Disposition , vol.35 , Issue.10 , pp. 1942-1948
    • Zheng, Y.1    Sun, D.2    Sharma, A.K.3    Chen, G.4    Amin, S.5    Lazarus, P.6
  • 25
    • 77952168953 scopus 로고    scopus 로고
    • The impact of CYP2D6 genotyping on tamoxifen treatment
    • Ferraldeschi, R.; Newman, W.G. The impact of CYP2D6 genotyping on tamoxifen treatment. Pharmaceuticals, 2010, 3, 1122-1138.
    • (2010) Pharmaceuticals , vol.3 , pp. 1122-1138
    • Ferraldeschi, R.1    Newman, W.G.2
  • 27
    • 0034885012 scopus 로고    scopus 로고
    • Role of drug metabolism in drug discovery and development
    • DOI 10.1002/med.1016
    • Kumar, G.N.; Surapaneni, S. Role of drug metabolism in drug discovery and development. Med. Res. Rev., 2001, 21, 397-411. (Pubitemid 32751462)
    • (2001) Medicinal Research Reviews , vol.21 , Issue.5 , pp. 397-411
    • Kumar, G.N.1    Surapaneni, S.2
  • 28
    • 4143147349 scopus 로고    scopus 로고
    • Discovering drugs through biological transformation: Role of pharmacologically active metabolites in drug discovery
    • DOI 10.1021/jm040066v
    • Fura, A.; Shu, Y.-Z.; Zhu, M.; Hanson, R.L.; Roongta, V.; Humphreys, W.G. Discovering drugs through biological transformation: role of pharmacologically active metabolites in drug discovery. J. Med. Chem., 2004, 47, 4339-4351. (Pubitemid 39096823)
    • (2004) Journal of Medicinal Chemistry , vol.47 , Issue.18 , pp. 4339-4351
    • Fura, A.1    Shu, Y.-Z.2    Zhu, M.3    Hanson, R.L.4    Roongta, V.5    Humphreys, W.G.6
  • 29
    • 33644859466 scopus 로고    scopus 로고
    • Role of pharmacologically active metabolites in drug discovery and development
    • DOI 10.1016/S1359-6446(05)03681-0, PII S1359644605036810
    • Fura, A. Role of pharmacologically active metabolites in drug discovery and development. Drug Discov. Today, 2006, 11 , 133-142. (Pubitemid 43375964)
    • (2006) Drug Discovery Today , vol.11 , Issue.3-4 , pp. 133-142
    • Fura, A.1
  • 30
    • 33846059783 scopus 로고    scopus 로고
    • Analytical tools and approaches for metabolite identification in early drug discovery
    • Chen, Y.; Monshouwer, M.; Fitch, W.L. Analytical tools and approaches for metabolite identification in early drug discovery. Pharm. Res., 2007, 24, 248-257.
    • (2007) Pharm. Res. , vol.24 , pp. 248-257
    • Chen, Y.1    Monshouwer, M.2    Fitch, W.L.3
  • 31
    • 42449137466 scopus 로고    scopus 로고
    • Biomimetic modeling of oxidative drug metabolism. Strategies, advantages and limitations
    • Lohmann, W.; Karst, U. Biomimetic modeling of oxidative drug metabolism. Strategies, advantages and limitations. Anal. Bioanal. Chem., 2008, 391, 79-96.
    • (2008) Anal. Bioanal. Chem. , vol.391 , pp. 79-96
    • Lohmann, W.1    Karst, U.2
  • 32
    • 51249100615 scopus 로고    scopus 로고
    • Role of biotransformation studies in minimizing metabolism-related liabilities in drug discovery
    • Shu, Y.-Z.; Johnson, B.M.; Yang, T.J. Role of biotransformation studies in minimizing metabolism-related liabilities in drug discovery. AAPS J., 2008, 10, 178-192.
    • (2008) AAPS J. , vol.10 , pp. 178-192
    • Shu, Y.-Z.1    Johnson, B.M.2    Yang, T.J.3
  • 35
    • 0142197899 scopus 로고    scopus 로고
    • Analysis of pharmaceuticals and biological fluids using modern electroanalytical techniques
    • Özkan, S.A.; Uslu, B.; Aboul-Enein, H.Y. Analysis of pharmaceuticals and biological fluids using modern electroanalytical techniques. Crit. Rev. Anal. Chem., 2003, 33, 155-181.
    • (2003) Crit. Rev. Anal. Chem. , vol.33 , pp. 155-181
    • Özkan, S.A.1    Uslu, B.2    Aboul-Enein, H.Y.3
  • 36
    • 34447260978 scopus 로고    scopus 로고
    • Electrochemical and spectroscopic characterisation of amphetamine-like drugs: Application to the screening of 3,4-methylenedioxymethamphetamine (MDMA) and its synthetic precursors
    • DOI 10.1016/j.aca.2007.06.027, PII S0003267007010604
    • Milhazes, N.; Martins, P.; Uriarte, E.; Garrido, J.; Calheiros, R.; Marques, M.P.M.; Borges, F. Electrochemical and spectroscopic characterisation of amphetamine-like drugs: application to the screening of 3,4- methylenedioxymethamphetamine (MDMA) and its synthetic precursors. Anal. (Pubitemid 47039235)
    • (2007) Analytica Chimica Acta , vol.596 , Issue.2 , pp. 231-241
    • Milhazes, N.1    Martins, P.2    Uriarte, E.3    Garrido, J.4    Calheiros, R.5    Marques, M.P.M.6    Borges, F.7
  • 37
    • 77955753851 scopus 로고    scopus 로고
    • Recent updates of chemically modified electrodes in pharmaceutical analysis
    • Radi, A.-E. Recent updates of chemically modified electrodes in pharmaceutical analysis. Comb. Chem. High Throughput Screen., 2010, 13, 728-752.
    • (2010) Comb. Chem. High Throughput Screen. , vol.13 , pp. 728-752
    • Radi, A.-E.1
  • 40
    • 0019882957 scopus 로고
    • An electrochemical interpretation of metabolism
    • Berry, M.N. An electrochemical interpretation of metabolism. FEBS Lett., 1981, 134, 133-138.
    • (1981) FEBS Lett. , vol.134 , pp. 133-138
    • Berry, M.N.1
  • 41
    • 0036002596 scopus 로고    scopus 로고
    • Some applications of electrochemistry in biomedical chemistry. Emphasis on the correlation of electrochemical and bioactive properties
    • Abreu, F.C.; Ferraz, P.A.L.; Goulart, M.O.F. Some applications of electrochemistry in biomedical chemistry. Emphasis on the correlation of electrochemical and bioactive properties. J. Braz. Chem. Soc., 2002, 13, 19-35.
    • (2002) J. Braz. Chem. Soc. , vol.13 , pp. 19-35
    • Abreu, F.C.1    Ferraz, P.A.L.2    Goulart, M.O.F.3
  • 43
    • 3342900320 scopus 로고    scopus 로고
    • Electrochemistry/mass spectrometry (EC/MS) - A new tool to study drug metabolism and reaction mechanisms
    • DOI 10.1002/anie.200301763
    • Karst, U. Electrochemistry/mass spectrometry (EC/MS) -A new tool to study drug metabolism and reaction mechanisms. Angew. Chem. Int. Ed., 2004, 43, 2476-2478. (Pubitemid 39257706)
    • (2004) Angewandte Chemie - International Edition , vol.43 , Issue.19 , pp. 2476-2478
    • Karst, U.1
  • 44
    • 0000634947 scopus 로고    scopus 로고
    • A thin-layer electrochemical flow cell coupled on-line with electrospray-mass spectrometry for the study of biological redox reactions
    • Deng, H.T.; Van Berkel, G.J. A thin-layer electrochemical flow cell coupled on-line with electrospray-mass spectrometry for the study of biological redox reactions. Electroanalysis, 1999, 11, 857-865.
    • (1999) Electroanalysis , vol.11 , pp. 857-865
    • Deng, H.T.1    Van Berkel, G.J.2
  • 45
    • 34547165961 scopus 로고    scopus 로고
    • Mimicry of phase I drug metabolism - Novel methods for metabolite characterization and synthesis
    • DOI 10.1002/rcm.3077
    • Johansson, T.; Weidolf, L.; Jurva, U. Mimicry of phase I drug metabolism -novel methods for metabolite characterization and synthesis. Rapid Commun. Mass Spectrom., 2007, 21, 2323-2331. (Pubitemid 47121164)
    • (2007) Rapid Communications in Mass Spectrometry , vol.21 , Issue.14 , pp. 2323-2331
    • Johansson, T.1    Weidolf, L.2    Jurva, U.3
  • 47
    • 34547344360 scopus 로고    scopus 로고
    • New analytical strategies in studying drug metabolism
    • DOI 10.1007/s00216-007-1367-z, Analytical Toxicol
    • Staack, R.F.; Hopfgartner, G. New analytical strategies in studying drug metabolism. Anal. (Pubitemid 47150867)
    • (2007) Analytical and Bioanalytical Chemistry , vol.388 , Issue.7 , pp. 1365-1380
    • Staack, R.F.1    Hopfgartner, G.2
  • 49
    • 18844373318 scopus 로고    scopus 로고
    • Role of metabolism in drug-induced idiosyncratic hepatotoxicity
    • DOI 10.1080/10408440590935620
    • Walgren, J.L.; Mitchell, M.D.; Thompson, D.C. Role of metabolism in drug-induced idiosyncratic hepatotoxicity. Crit. Rev. Toxi-col., 2005, 35, 325-361. (Pubitemid 40691298)
    • (2005) Critical Reviews in Toxicology , vol.35 , Issue.4 , pp. 325-361
    • Walgren, J.L.1    Mitchell, M.D.2    Thompson, D.C.3
  • 50
    • 18944401259 scopus 로고    scopus 로고
    • Elucidating mechanisms of drug-induced toxicity
    • DOI 10.1038/nrd1720
    • Liebler, D.C.; Guengerich, F.P. Elucidating mechanisms of drug-induced toxicity. Nat. Rev. Drug Discov., 2005, 4, 410-420. (Pubitemid 40704124)
    • (2005) Nature Reviews Drug Discovery , vol.4 , Issue.5 , pp. 410-420
    • Liebler, D.C.1    Guengerich, F.P.2
  • 51
    • 0034100506 scopus 로고    scopus 로고
    • In vitro mimicry of metabolic oxidation reactions by electrochemistry/ mass spectrometry
    • DOI 10.1002/(SICI)1097-0231(20000331)14:6<529::AID-RCM904>3.0.CO;2- H
    • Jurva, U.; Wikstrom, H. V.; Bruins, A. P. In vitro mimicry of metabolic oxidation reactions by electrochemistry/mass spectrome-try. Rapid Commun. Mass Spectrom., 2000, 14, 529-533. (Pubitemid 30153006)
    • (2000) Rapid Communications in Mass Spectrometry , vol.14 , Issue.6 , pp. 529-533
    • Jurva, U.1    Wikstrom, H.V.2    Bruins, A.P.3
  • 52
    • 40049111087 scopus 로고    scopus 로고
    • Electrochemistry-mass spectrometry in drug metabolism and protein research
    • DOI 10.2174/138955708783331586
    • Permentier, H.P.; Bruins, A.P.; Bischoff, R. Electrochemistry-Mass spectrometry in drug metabolism and protein research. Mini Rev. Med. Chem., 2008, 8, 46-56. (Pubitemid 351320929)
    • (2008) Mini-Reviews in Medicinal Chemistry , vol.8 , Issue.1 , pp. 46-56
    • Permentier, H.P.1    Bruins, A.P.2    Bischoff, R.3
  • 53
    • 77955740272 scopus 로고    scopus 로고
    • Stability and drug metabolism assessed by electrochemical methods
    • Alvarez-Lueje, A.; Dragnic, S. B. Stability and drug metabolism assessed by electrochemical methods. Comb. Chem. High Throughput Screen., 2010, 13, 712-727.
    • (2010) Comb. Chem. High Throughput Screen. , vol.13 , pp. 712-727
    • Alvarez-Lueje, A.1    Dragnic, S.B.2
  • 54
    • 67449133537 scopus 로고    scopus 로고
    • Electrochemistry meets enzymes: Instrumental on-line simulation of oxidative and conjugative metabolism reactions of toremifene
    • Lohmann, W.; Karst, U. Electrochemistry meets enzymes: instrumental on-line simulation of oxidative and conjugative metabolism reactions of toremifene. Anal. Bioanal. Chem., 2009, 394, 1341-1348.
    • (2009) Anal. Bioanal. Chem. , vol.394 , pp. 1341-1348
    • Lohmann, W.1    Karst, U.2
  • 56
    • 77952069805 scopus 로고    scopus 로고
    • Electrochemistry and LC-MS for metabolite generation and identification: Tools, technologies and trends
    • Lohmann, W.; Baumann, A; Karst, U. Electrochemistry and LC-MS for metabolite generation and identification: tools, technologies and trends. LC GC Eur., 2010, 23, 8-16.
    • (2010) LC GC Eur. , vol.23 , pp. 8-16
    • Lohmann, W.1    Baumann, A.2    Karst, U.3
  • 57
    • 0036861737 scopus 로고    scopus 로고
    • Electrochemical sensors for DNA interactions and damage
    • Fojta, M. Electrochemical sensors for DNA interactions and damage. Electroanalysis, 2002, 14, 1449-1463.
    • (2002) Electroanalysis , vol.14 , pp. 1449-1463
    • Fojta, M.1
  • 59
    • 1342308239 scopus 로고    scopus 로고
    • Recent trends in electrochemical DNA biosensor technology
    • PII S0957023304569710
    • Kerman, K.; Kobayashi, M.; Tamiya, E. Recent trends in electrochemical DNA biosensor technology. Meas. Sci. Technol., 2004, 15, R1-R11. (Pubitemid 38261613)
    • (2004) Measurement Science and Technology , vol.15 , Issue.2
    • Kerman, K.1    Kobayashi, M.2    Tamiya, E.3
  • 60
    • 38749088409 scopus 로고    scopus 로고
    • Grimes, C.A.; Dickey, E.C.; Pishko, M.V., Eds.; American Scientific Publishers: California
    • Oliveira-Brett, A.M. In: Encyclopedia of Sensors, Grimes, C.A.; Dickey, E.C.; Pishko, M.V., Eds.; American Scientific Publishers: California, 2006; Vol. 3, pp. 301-314.
    • (2006) Encyclopedia of Sensors , vol.3 , pp. 301-314
    • Oliveira-Brett, A.M.1
  • 63
    • 0343623317 scopus 로고
    • Polarographic studies of drugs of triphenylethene derivatives
    • Fijalek, Z.; Chodkowski, J.; Warowna, M. Polarographic studies of drugs of triphenylethene derivatives. J. Electroanal. Chem., 1987, 226, 129-136.
    • (1987) J. Electroanal. Chem. , vol.226 , pp. 129-136
    • Fijalek, Z.1    Chodkowski, J.2    Warowna, M.3
  • 64
    • 0030662988 scopus 로고    scopus 로고
    • Adsorptive potentiometric stripping analysis of trace tamoxifen at a glassy carbon electrode
    • DOI 10.1016/S0039-9140(97)00129-X, PII S003991409700129X
    • Wang, J.; Cai, X.; Fernandes, J.R.; Ozsoz, M.; Grant, D.H. Adsorp-tive potentiometric stripping analysis of trace tamoxifen at a glassy carbon electrode. Talanta, 1997, 45, 273-278. (Pubitemid 27506664)
    • (1997) Talanta , vol.45 , Issue.2 , pp. 273-278
    • Wang, J.1    Cai, X.2    Fernandes, J.R.3    Ozsoz, M.4    Grant, D.H.5
  • 65
    • 47249145599 scopus 로고    scopus 로고
    • Single-sweep voltammetric determination of tamoxifen at carbon paste electrode
    • DOI 10.1080/00032710802052668, PII 794890799
    • Guo, X.-X.; Song, Z.-J.; Tian, X.-J.; Song, J.-F. Single-sweep voltammetric determination of tamoxifen at carbon paste electrode. Anal. (Pubitemid 351990063)
    • (2008) Analytical Letters , vol.41 , Issue.7 , pp. 1225-1235
    • Guo, X.-X.1    Song, Z.-J.2    Tian, X.-J.3    Song, J.-F.4
  • 66
    • 2042518739 scopus 로고
    • Electrochemical oxidation of phen-ylethylenes. I. Conversion of tetraphenylethylene to 9,10-diphenylphenanthrene
    • 36
    • Stuart, J.D.; Ohnesorge, W.E. Electrochemical oxidation of phen-ylethylenes. I. Conversion of tetraphenylethylene to 9,10- diphenylphenanthrene. J. Am. Chem. Soc., 1971, 93, 45 31-45 36.
    • (1971) J. Am. Chem. Soc. , vol.93 , Issue.45 , pp. 31-45
    • Stuart, J.D.1    Ohnesorge, W.E.2
  • 71
    • 69949113190 scopus 로고    scopus 로고
    • And norfluoxetine revisited: New insights into the electrochemical and spectroscopic properties
    • Garrido, E.M.; Garrido, J.; Calheiros, R.; Marques, M.P.M.; Borges, F. Fluoxetine and norfluoxetine revisited: new insights into the electrochemical and spectroscopic properties. J. Phys. Chem. A., 2009, 773, 9934-9944.
    • (2009) J. Phys. Chem. A. , vol.773 , pp. 9934-9944
    • Garrido, E.M.1    Garrido, J.2    Calheiros, R.3    Marques, M.P.M.4    Fluoxetine, B.F.5
  • 72
    • 0024791180 scopus 로고
    • Determination of 2-methyl derivatives of tamoxifen in cell culture medium using high-performance liquid chromatography and electrochemical detection
    • DOI 10.1016/S0378-4347(00)82584-0
    • Chamart, S.; Hanocq, M.; Helson, M.; Devleeschouwer, N.; Le-clercq, G. Determination of 2-methyl derivatives of tamoxifen in cell culture medium using high-performance liquid chromatogra-phy and electrochemical detection. J. Chromatogr. B., 1989, 496, 365-375. (Pubitemid 20010702)
    • (1989) Journal of Chromatography - Biomedical Applications , vol.496 , Issue.2 , pp. 365-375
    • Chamart, S.1    Hanocq, M.2    Helson, M.3    Devleeschouwer, N.4    Leclercq, G.5
  • 73
    • 57049152307 scopus 로고    scopus 로고
    • Ultrasensitive flow-injection electrochemical method for detection of anti-cancer drug tamoxifen
    • Daneshgar, P.; Norouzi, P.; Ganjali, M.R.; Zamani, H.A. Ultrasensitive flow-injection electrochemical method for detection of anti-cancer drug tamoxifen. Talanta, 2009, 77, 1075-1080.
    • (2009) Talanta , vol.77 , pp. 1075-1080
    • Daneshgar, P.1    Norouzi, P.2    Ganjali, M.R.3    Zamani, H.A.4
  • 74
    • 62249123949 scopus 로고    scopus 로고
    • Differences in metabolite-mediated toxicity of tamoxifen in rodents versus humans elucidated with DNA/microsome electro-optical arrays and nanoreactors
    • Zhao, L.; Krishnan, S.; Zhang, Y.; Schenkman, J.B.; Rusling, J.F. Differences in metabolite-mediated toxicity of tamoxifen in rodents versus humans elucidated with DNA/microsome electro-optical arrays and nanoreactors. Chem. Res. Toxicol., 2009, 22, 341-347.
    • (2009) Chem. Res. Toxicol. , vol.22 , pp. 341-347
    • Zhao, L.1    Krishnan, S.2    Zhang, Y.3    Schenkman, J.B.4    Rusling, J.F.5
  • 75
    • 33645232520 scopus 로고    scopus 로고
    • Electrochemical biosensors: Towards point of care cancer diagnostics
    • Wang, J. Electrochemical biosensors: towards point of care cancer diagnostics. Biosens. Bioelectron., 2006, 27, 1887-1892.
    • (2006) Biosens. Bioelectron. , vol.27 , pp. 1887-1892
    • Wang, J.1
  • 76
    • 61849104074 scopus 로고    scopus 로고
    • Biosensors for cancer markers diagnosis
    • Tothill, I.E. Biosensors for cancer markers diagnosis. Semin. Cell Dev. Biol., 2009, 20, 55-62.
    • (2009) Semin. Cell Dev. Biol. , vol.20 , pp. 55-62
    • Tothill, I.E.1


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.