CP-MLR/PLS directed QSAR study on apical sodium-codependent bile acid transporter inhibition activity of benzothiepines

Molecular Diversity

Volumn 15, Issue 1, 2011, Pages 135-147

  Sharma, Brij Kishore ^a   Singh, Prithvi ^a   Pilania, Pradeep ^a   Sarbhai, Kirti ^a   Prabhakar, Yenamandra S ^b  

^a SK Government College   (India)

^b CENTRAL DRUG RESEARCH INSTITUTE   (India)

Author keywords

Apical sodium codependent bile acid transporter (ASBT) inhibitors; Benzothiepines; Combinatorial protocol in multiple linear regression; Dragon descriptors; QSAR

Indexed keywords

APICAL SODIUM CODEPENDENT BILE ACID TRANSPORTER; AROMATIC AMINE; DIBENZOTHIEPIN DERIVATIVE; FUNCTIONAL GROUP; ORGANIC ANION TRANSPORTER; UNCLASSIFIED DRUG;

ACF; ARTICLE; BELM2; BELM4; BELV2; BIOLOGICAL ACTIVITY; CHEMICAL ANALYSIS; CHEMICAL STRUCTURE; ELECTRON; ENZYME LOCALIZATION; GATS4V; GATS6E; GG12; INHIBITION KINETICS; JG12; JG15; JG16; MASS; MATS4M; MATS4P; MATS5M; MATS7V; MATS8M; MOLECULAR MODEL; MULTIPLE LINEAR REGRESSION ANALYSIS; NNR2PH; PARTIAL LEAST SQUARES REGRESSION; POL; POLARIZATION; PRIORITY JOURNAL; PW3; PW5; QUANTITATIVE STRUCTURE ACTIVITY RELATION; RAM; RANDIC SHAPE INDEX; STATISTICAL ANALYSIS; VOLUMETRY; X5V;

COMBINATORIAL CHEMISTRY TECHNIQUES; CYCLIC N-OXIDES; LINEAR MODELS; ORGANIC ANION TRANSPORTERS, SODIUM-DEPENDENT; QUANTITATIVE STRUCTURE-ACTIVITY RELATIONSHIP; SYMPORTERS;

EID: 79953320730     PISSN: 13811991     EISSN: None     Source Type: Journal    
DOI: 10.1007/s11030-009-9220-2     Document Type: Article

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