Topological descriptors in modeling malonyl coenzyme A decarboxylase inhibitory activity: N-Alkyl-N-(1,1,1,3,3,3-hexafluoro-2-hydroxypropylphenyl) amide derivatives

Journal of Enzyme Inhibition and Medicinal Chemistry

Volumn 24, Issue 1, 2009, Pages 77-85

  Singh, P ^a   Kumar, R ^a   Sharma, B K ^a   Prabhakar, Y S ^b  

^a Department of Chemistry ^*  (India)

^b CENTRAL DRUG RESEARCH INSTITUTE   (India)

Author keywords

Combinatorial protocol in multiple linear regression (CP MLR); Malonyl CoA decarboxylase inhibitors (MCD); N alkyl N (1,1,1,3,3,3 hexafluoro 2 hydroxypropylphenyl)amides; Quantitative structure activity relationship (QSAR); Topological descriptors

Indexed keywords

AMIDE; MALONYL COENZYME A DECARBOXYLASE; N ALKYL N (1,1,1,3,3,3 HEXAFLUORO 2 HYDROXYPROPYLPHENYL)AMIDE DERIVATIVE; UNCLASSIFIED DRUG;

ARTICLE; COMBINATORIAL CHEMISTRY; COMPUTER PROGRAM; CONTROLLED STUDY; DRUG ACTIVITY; DRUG STRUCTURE; ENZYME INHIBITION; IC 50; MOLECULAR MODEL; PRIORITY JOURNAL; QUANTITATIVE STRUCTURE ACTIVITY RELATION;

ANILINE COMPOUNDS; CARBOXY-LYASES; COMPUTER SIMULATION; HUMANS; MALONYL COENZYME A; MODELS, MOLECULAR; SOFTWARE;

EID: 58949092759     PISSN: 14756366     EISSN: 14756374     Source Type: Journal    
DOI: 10.1080/14756360801915336     Document Type: Article

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