Helicobacter hepaticus-induced liver tumor promotion is associated with increased serum bile acid and a persistent microbial-induced immune response

Cancer Research

Volumn 71, Issue 7, 2011, Pages 2529-2540

  García, Alexis ^a   Zeng, Yu ^b   Muthupalani, Sureshkumar ^a   Ge, Zhongming ^a   Potter, Amanda ^a   Mobley, Melissa W ^a   Boussahmain, Chakib ^a   Feng, Yan ^a   Wishnok, John S ^a   Fox, James G ^a,b  

^a MASSACHUSETTS INSTITUTE OF TECHNOLOGY   (United States)

^b Massachusetts Institute of Technology Cambridge   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

BILE ACID; CHENODEOXYCHOLIC ACID; CONSTITUTIVE ANDROSTANE RECEPTOR; CYTOCHROME P450; CYTOCHROME P450 2B10; CYTOCHROME P450 3A11; DIETHYLNITROSAMINE; TOLL LIKE RECEPTOR 2; TUMOR NECROSIS FACTOR ALPHA; UNCLASSIFIED DRUG;

ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ARTICLE; BILE ACID BLOOD LEVEL; CANCER GROWTH; CONTROLLED STUDY; DYSPLASIA; GENE EXPRESSION; HELICOBACTER HEPATICUS; HELICOBACTER INFECTION; HEPATITIS; HISTOPATHOLOGY; IMMUNE RESPONSE; KNOCKOUT MOUSE; LIVER CANCER; LIVER CARCINOGENESIS; MALE; MICROBIOLOGICAL EXAMINATION; MOUSE; NONHUMAN; PRIORITY JOURNAL; UPREGULATION; WILD TYPE;

ANIMALS; ARYL HYDROCARBON HYDROXYLASES; BETA CATENIN; BILE ACIDS AND SALTS; CYTOCHROME P-450 CYP3A; DOWN-REGULATION; GENE EXPRESSION REGULATION, ENZYMOLOGIC; GENE EXPRESSION REGULATION, NEOPLASTIC; HELICOBACTER HEPATICUS; HELICOBACTER INFECTIONS; LIVER NEOPLASMS, EXPERIMENTAL; MALE; MEMBRANE PROTEINS; MICE; MICE, INBRED C3H; MICE, INBRED C57BL; MICE, KNOCKOUT; RECEPTORS, CYTOPLASMIC AND NUCLEAR; STEROID HYDROXYLASES; TOLL-LIKE RECEPTOR 2; TUMOR NECROSIS FACTOR-ALPHA;

EID: 79953311870     PISSN: 00085472     EISSN: 15387445     Source Type: Journal    
DOI: 10.1158/0008-5472.CAN-10-1975     Document Type: Article

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