9-oxo-10(E),12(E)-octadecadienoic acid derived from tomato is a potent PPAR α agonist to decrease triglyceride accumulation in mouse primary hepatocytes

Molecular Nutrition and Food Research

Volumn 55, Issue 4, 2011, Pages 585-593

  Kim, Young Il ^a   Hirai, Shizuka ^a   Takahashi, Haruya ^a   Goto, Tsuyoshi ^a   Ohyane, Chie ^a   Tsugane, Taneaki ^b   Konishi, Chiaki ^c   Fujii, Takashi ^c   Inai, Shuji ^c   Iijima, Yoko ^d   Aoki, Koh ^d   Shibata, Daisuke ^d   Takahashi, Nobuyuki ^a   Kawada, Teruo ^a  

^a KYOTO UNIVERSITY   (Japan)

^b Chiba Prefectural Agriculture and Forestry Research Center 1762   (Japan)

^c Nippon Del Monte Corporation   (Japan)

^d Kazusa DNA Research Institutes   (Japan)

Author keywords

Dyslipidemia; Fatty acid oxidation; Oxylipin; PPAR ; Tomato

Indexed keywords

9 OXO 10,12 OCTADECADIENOIC ACID; 9-OXO-10,12-OCTADECADIENOIC ACID; LINOLENIC ACID; MESSENGER RNA; PEROXISOME PROLIFERATOR ACTIVATED RECEPTOR ALPHA; PLANT EXTRACT; TRIACYLGLYCEROL;

ANIMAL; ARTICLE; C57BL MOUSE; CELL CULTURE; CHEMISTRY; DRUG ANTAGONISM; DRUG EFFECT; DRUG POTENTIATION; DYSLIPIDEMIA; FRUIT; GENE EXPRESSION REGULATION; GENETICS; ISOLATION AND PURIFICATION; ISOMERISM; LIPID METABOLISM; LIVER CELL; MALE; METABOLISM; MOUSE; OXYGEN CONSUMPTION; REPORTER GENE; TOMATO;

ANIMALS; CELLS, CULTURED; DYSLIPIDEMIAS; FRUIT; GENE EXPRESSION REGULATION; GENES, REPORTER; HEPATOCYTES; ISOMERISM; LINOLENIC ACIDS; LIPID METABOLISM; LYCOPERSICON ESCULENTUM; MALE; MICE; MICE, INBRED C57BL; OXYGEN CONSUMPTION; PLANT EXTRACTS; PPAR ALPHA; RNA, MESSENGER; TRIGLYCERIDES;

LYCOPERSICON ESCULENTUM;

EID: 79953297693     PISSN: 16134125     EISSN: 16134133     Source Type: Journal    
DOI: 10.1002/mnfr.201000264     Document Type: Article

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