-
2
-
-
33646033137
-
A lentiviral RNAi library for human and mouse genes applied to an arrayed viral high-content screen
-
J. Moffat A lentiviral RNAi library for human and mouse genes applied to an arrayed viral high-content screen Cell 124 2006 1283 1298
-
(2006)
Cell
, vol.124
, pp. 1283-1298
-
-
Moffat, J.1
-
3
-
-
33747794587
-
Genome-scale loss-of-function screening with a lentiviral RNAi library
-
DOI 10.1038/nmeth924, PII NMETH924
-
D.E. Root, N. Hacohen, W.C. Hahn, E.S. Lander, and D.M. Sabatini Genome-scale loss-of-function screening with a lentiviral RNAi library Nat. Methods 3 2006 715 719 (Pubitemid 44275739)
-
(2006)
Nature Methods
, vol.3
, Issue.9
, pp. 715-719
-
-
Root, D.E.1
Hacohen, N.2
Hahn, W.C.3
Lander, E.S.4
Sabatini, D.M.5
-
4
-
-
34249993765
-
Integrative Genomic Approaches Identify IKBKE as a Breast Cancer Oncogene
-
DOI 10.1016/j.cell.2007.03.052, PII S0092867407005326
-
J.S. Boehm Integrative genomic approaches identify IKBKE as a breast cancer oncogene Cell 129 2007 1065 1079 (Pubitemid 46891036)
-
(2007)
Cell
, vol.129
, Issue.6
, pp. 1065-1079
-
-
Boehm, J.S.1
Zhao, J.J.2
Yao, J.3
Kim, S.Y.4
Firestein, R.5
Dunn, I.F.6
Sjostrom, S.K.7
Garraway, L.A.8
Weremowicz, S.9
Richardson, A.L.10
Greulich, H.11
Stewart, C.J.12
Mulvey, L.A.13
Shen, R.R.14
Ambrogio, L.15
Hirozane-Kishikawa, T.16
Hill, D.E.17
Vidal, M.18
Meyerson, M.19
Grenier, J.K.20
Hinkle, G.21
Root, D.E.22
Roberts, T.M.23
Lander, E.S.24
Polyak, K.25
Hahn, W.C.26
more..
-
5
-
-
52949111487
-
CDK8 is a colorectal cancer oncogene that regulates beta-catenin activity
-
R. Firestein CDK8 is a colorectal cancer oncogene that regulates beta-catenin activity Nature 455 2008 547 551
-
(2008)
Nature
, vol.455
, pp. 547-551
-
-
Firestein, R.1
-
6
-
-
38349088899
-
Identification of RPS14 as a 5q-syndrome gene by RNA interference screen
-
B.L. Ebert Identification of RPS14 as a 5q-syndrome gene by RNA interference screen Nature 451 2008 335 339
-
(2008)
Nature
, vol.451
, pp. 335-339
-
-
Ebert, B.L.1
-
7
-
-
67149115119
-
Transfection of small RNAs globally perturbs gene regulation by endogenous microRNAs
-
A.A. Khan, D. Betel, M.L. Miller, C. Sander, C.S. Leslie, and D.S. Marks Transfection of small RNAs globally perturbs gene regulation by endogenous microRNAs Nat. Biotechnol. 27 2009 549 555
-
(2009)
Nat. Biotechnol.
, vol.27
, pp. 549-555
-
-
Khan, A.A.1
Betel, D.2
Miller, M.L.3
Sander, C.4
Leslie, C.S.5
Marks, D.S.6
-
8
-
-
34250354423
-
Identification of host genes involved in hepatitis C virus replication by small interfering RNA technology
-
DOI 10.1002/hep.21608
-
T.I. Ng Identification of host genes involved in hepatitis C virus replication by small interfering RNA technology Hepatology 45 2007 1413 1421 (Pubitemid 46918325)
-
(2007)
Hepatology
, vol.45
, Issue.6
, pp. 1413-1421
-
-
Ng, T.I.1
Mo, H.2
Pilot-Matias, T.3
He, Y.4
Koev, G.5
Krishnan, P.6
Mondal, R.7
Pithawalla, R.8
He, W.9
Dekhtyar, T.10
Packer, J.11
Schurdak, M.12
Molla, A.13
-
9
-
-
34547913440
-
Cellular cofactors affecting hepatitis C virus infection and replication
-
DOI 10.1073/pnas.0704894104
-
G. Randall Cellular cofactors affecting hepatitis C virus infection and replication Proc. Natl. Acad. Sci. USA 104 2007 12884 12889 (Pubitemid 47255249)
-
(2007)
Proceedings of the National Academy of Sciences of the United States of America
, vol.104
, Issue.31
, pp. 12884-12889
-
-
Randall, G.1
Panis, M.2
Cooper, J.D.3
Tellinghuisen, T.L.4
Sukhodolets, K.E.5
Pfeffer, S.6
Landthaler, M.7
Landgraf, P.8
Kan, S.9
Lindenbach, B.D.10
Chien, M.11
Weir, D.B.12
Russo, J.J.13
Ju, J.14
Brownstein, M.J.15
Sheridan, R.16
Sander, C.17
Zavolan, M.18
Tuschl, T.19
Rice, C.M.20
more..
-
10
-
-
61849160363
-
A functional genomic screen identifies cellular cofactors of hepatitis C virus replication
-
A.W. Tai, Y. Benita, L.F. Peng, S.S. Kim, N. Sakamoto, R.J. Xavier, and R.T. Chung A functional genomic screen identifies cellular cofactors of hepatitis C virus replication Cell Host Microbe 5 2009 298 307
-
(2009)
Cell Host Microbe
, vol.5
, pp. 298-307
-
-
Tai, A.W.1
Benita, Y.2
Peng, L.F.3
Kim, S.S.4
Sakamoto, N.5
Xavier, R.J.6
Chung, R.T.7
-
11
-
-
70349513508
-
A genome-wide genetic screen for host factors required for hepatitis C virus propagation
-
Q. Li, A.L. Brass, A. Ng, Z. Hu, R.J. Xavier, T.J. Liang, and S.J. Elledge A genome-wide genetic screen for host factors required for hepatitis C virus propagation Proc. Natl. Acad. Sci. USA 106 2009 16410 16415
-
(2009)
Proc. Natl. Acad. Sci. USA
, vol.106
, pp. 16410-16415
-
-
Li, Q.1
Brass, A.L.2
Ng, A.3
Hu, Z.4
Xavier, R.J.5
Liang, T.J.6
Elledge, S.J.7
-
12
-
-
33748081146
-
Simultaneous targeting of HCV replication and viral binding with a single lentiviral vector containing multiple RNA interference expression cassettes
-
DOI 10.1016/j.ymthe.2006.04.012, PII S1525001606002024
-
S.D. Henry, P. van der Wegen, H.J. Metselaar, H.W. Tilanus, B.J. Scholte, and L.J. van der Laan Simultaneous targeting of HCV replication and viral binding with a single lentiviral vector containing multiple RNA interference expression cassettes Mol. Ther. 14 2006 485 493 (Pubitemid 44296093)
-
(2006)
Molecular Therapy
, vol.14
, Issue.4
, pp. 485-493
-
-
Henry, S.D.1
Van Der Wegen, P.2
Metselaar, H.J.3
Tilanus, H.W.4
Scholte, B.J.5
Van Der Laan, L.J.W.6
-
13
-
-
67649442530
-
Combined antiviral activity of interferon-alpha and RNA interference directed against hepatitis C without affecting vector delivery and gene silencing
-
Q. Pan, S.D. Henry, H.J. Metselaar, B. Scholte, J. Kwekkeboom, H.W. Tilanus, H.L. Janssen, and L.J. van der Laan Combined antiviral activity of interferon-alpha and RNA interference directed against hepatitis C without affecting vector delivery and gene silencing J. Mol. Med. 87 2009 713 722
-
(2009)
J. Mol. Med.
, vol.87
, pp. 713-722
-
-
Pan, Q.1
Henry, S.D.2
Metselaar, H.J.3
Scholte, B.4
Kwekkeboom, J.5
Tilanus, H.W.6
Janssen, H.L.7
Van Der Laan, L.J.8
-
14
-
-
77955886412
-
Lentiviral gene therapy of murine hematopoietic stem cells ameliorates the Pompe disease phenotype
-
N.P. van Til Lentiviral gene therapy of murine hematopoietic stem cells ameliorates the Pompe disease phenotype Blood 115 2010 5329 5337
-
(2010)
Blood
, vol.115
, pp. 5329-5337
-
-
Van Til, N.P.1
-
16
-
-
33750219537
-
Hepatitis C virus RNA replication is regulated by FKBP8 and Hsp90
-
DOI 10.1038/sj.emboj.7601367, PII 7601367
-
T. Okamoto, Y. Nishimura, T. Ichimura, K. Suzuki, T. Miyamura, T. Suzuki, K. Moriishi, and Y. Matsuura Hepatitis C virus RNA replication is regulated by FKBP8 and Hsp90 EMBO J. 25 2006 5015 5025 (Pubitemid 44607045)
-
(2006)
EMBO Journal
, vol.25
, Issue.20
, pp. 5015-5025
-
-
Okamoto, T.1
Nishimura, Y.2
Ichimura, T.3
Suzuki, K.4
Miyamura, T.5
Suzuki, T.6
Moriishi, K.7
Matsuura, Y.8
-
17
-
-
27144479794
-
Dissecting the interferon-induced inhibition of hepatitis C virus replication by using a novel host cell line
-
DOI 10.1128/JVI.79.21.13778-13793.2005
-
M.P. Windisch, M. Frese, A. Kaul, M. Trippler, V. Lohmann, and R. Bartenschlager Dissecting the interferon-induced inhibition of hepatitis C virus replication by using a novel host cell line J. Virol. 79 2005 13778 13793 (Pubitemid 41508189)
-
(2005)
Journal of Virology
, vol.79
, Issue.21
, pp. 13778-13793
-
-
Windisch, M.P.1
Frese, M.2
Kaul, A.3
Trippier, M.4
Lohmann, V.5
Bartenschlager, R.6
-
18
-
-
33646237345
-
Stable RNA interference. Comparison of U6 and H1 promoters in endothelial cells and in mouse brain
-
P.I. Makinen, J.K. Koponen, A.M. Karkkainen, T.M. Malm, K.H. Pulkkinen, J. Koistinaho, M.P. Turunen, and S. Yla-Herttuala Stable RNA interference. Comparison of U6 and H1 promoters in endothelial cells and in mouse brain J. Gene Med. 8 2006 433 441
-
(2006)
J. Gene Med.
, vol.8
, pp. 433-441
-
-
Makinen, P.I.1
Koponen, J.K.2
Karkkainen, A.M.3
Malm, T.M.4
Pulkkinen, K.H.5
Koistinaho, J.6
Turunen, M.P.7
Yla-Herttuala, S.8
-
19
-
-
39849108343
-
Lentiviral vector design for multiple shRNA expression and durable HIV-1 inhibition
-
DOI 10.1038/sj.mt.6300382, PII 6300382
-
O. ter Brake, K. t Hooft, Y.P. Liu, M. Centlivre, K.J. von Eije, and B. Berkhout Lentiviral vector design for multiple shRNA expression and durable HIV-1 inhibition Mol. Ther. 16 2008 557 564 (Pubitemid 351314996)
-
(2008)
Molecular Therapy
, vol.16
, Issue.3
, pp. 557-564
-
-
Ter Brake, O.1
'T Hooft, K.2
Liu, Y.P.3
Centlivre, M.4
Von Eije, K.J.5
Berkhout, B.6
-
20
-
-
33745299723
-
Fatality in mice due to oversaturation of cellular microRNA/short hairpin RNA pathways
-
DOI 10.1038/nature04791, PII NATURE04791
-
D. Grimm Fatality in mice due to oversaturation of cellular microRNA/short hairpin RNA pathways Nature 441 2006 537 541 (Pubitemid 44050158)
-
(2006)
Nature
, vol.441
, Issue.7092
, pp. 537-541
-
-
Grimm, D.1
Streetz, K.L.2
Jopling, C.L.3
Storm, T.A.4
Pandey, K.5
Davis, C.R.6
Marion, P.7
Salazar, F.8
Kay, M.A.9
-
21
-
-
24644483623
-
Molecular biology: Modulation of hepatitis C virus RNA abundance by a liver-specific MicroRNA
-
DOI 10.1126/science.1113329
-
C.L. Jopling, M. Yi, A.M. Lancaster, S.M. Lemon, and P. Sarnow Modulation of hepatitis C virus RNA abundance by a liver-specific MicroRNA Science 309 2005 1577 1581 (Pubitemid 41266486)
-
(2005)
Science
, vol.309
, Issue.5740
, pp. 1577-1581
-
-
Jopling, C.L.1
Yi, M.2
Lancaster, A.M.3
Lemon, S.M.4
Sarnow, P.5
-
22
-
-
77953315225
-
Regulation of hepatitis C virus translation and infectious virus production by the microRNA miR-122
-
R.K. Jangra, M. Yi, and S.M. Lemon Regulation of hepatitis C virus translation and infectious virus production by the microRNA miR-122 J. Virol. 84 2010 6615 6625
-
(2010)
J. Virol.
, vol.84
, pp. 6615-6625
-
-
Jangra, R.K.1
Yi, M.2
Lemon, S.M.3
-
23
-
-
74249112787
-
Therapeutic silencing of microRNA-122 in primates with chronic hepatitis C virus infection
-
R.E. Lanford, E.S. Hildebrandt-Eriksen, A. Petri, R. Persson, M. Lindow, M.E. Munk, S. Kauppinen, and H. Orum Therapeutic silencing of microRNA-122 in primates with chronic hepatitis C virus infection Science 327 2010 198 201
-
(2010)
Science
, vol.327
, pp. 198-201
-
-
Lanford, R.E.1
Hildebrandt-Eriksen, E.S.2
Petri, A.3
Persson, R.4
Lindow, M.5
Munk, M.E.6
Kauppinen, S.7
Orum, H.8
-
24
-
-
67651007766
-
MiR-122/cyclin G1 interaction modulates p53 activity and affects doxorubicin sensitivity of human hepatocarcinoma cells
-
F. Fornari MiR-122/cyclin G1 interaction modulates p53 activity and affects doxorubicin sensitivity of human hepatocarcinoma cells Cancer Res. 69 2009 5761 5767
-
(2009)
Cancer Res.
, vol.69
, pp. 5761-5767
-
-
Fornari, F.1
-
25
-
-
77956355233
-
Argonaute proteins are key determinants of RNAi efficacy, toxicity, and persistence in the adult mouse liver
-
D. Grimm, L. Wang, J.S. Lee, N. Schurmann, S. Gu, K. Borner, T.A. Storm, and M.A. Kay Argonaute proteins are key determinants of RNAi efficacy, toxicity, and persistence in the adult mouse liver J. Clin. Invest. 120 2010 3106 3119
-
(2010)
J. Clin. Invest.
, vol.120
, pp. 3106-3119
-
-
Grimm, D.1
Wang, L.2
Lee, J.S.3
Schurmann, N.4
Gu, S.5
Borner, K.6
Storm, T.A.7
Kay, M.A.8
|