Differences between human wild-type and C23S variant 5-HT2C receptors in inverse agonist-induced resensitization

Pharmacological Reports

Volumn 63, Issue 1, 2011, Pages 45-53

  Walstab, Jutta ^a   Steinhagen, Folkert ^a   Brüss, Michael ^a   Göthert, Manfred ^a   Bönisch, Heinz ^a  

^a UNIVERSITY OF BONN   (Germany)

Author keywords

Aequorin; C23S variant; Calcium; HEK293 cells; Inverse agonist; Receptor desensitization; SB 206553

Indexed keywords

1,2,3,5 TETRAHYDRO 5 METHYL 1 (3 PYRIDYLCARBAMOYL)PYRROLO[2,3 F]INDOLE; CALCIUM ION; SEROTONIN; SEROTONIN 2C RECEPTOR;

ARTICLE; CALCIUM CELL LEVEL; CELL STRAIN HEK293; CONTROLLED STUDY; DRUG EXPOSURE; DRUG MECHANISM; HUMAN; HUMAN CELL; NUCLEOTIDE SEQUENCE; PROTEIN EXPRESSION; PROTEIN VARIANT; RECEPTOR DOWN REGULATION; RESENSITIZATION; SENSITIZATION; WILD TYPE;

EID: 79953210123     PISSN: 22995684     EISSN: 22995684     Source Type: Journal    
DOI: 10.1016/S1734-1140(11)70397-8     Document Type: Article

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