Different regulation of rat 5-HT2A and rat 5-HT2C receptors in NIH 3T3 cells upon exposure to 5-HT and pipamperone

European Journal of Pharmacology

Volumn 425, Issue 1, 2001, Pages 21-32

  Oekelen, Dirk Van ^a   Jurzak, Mirek ^a   Van de Wiel, Danielle ^a   Van Hecke, Geert ^a   Luyten, Walter H M L ^a   Leysen, Josée E ^a  

^a JANSSEN RESEARCH FOUNDATION   (Belgium)

Author keywords

5 HT2A receptor; 5 HT2C receptor; Agonist binding site; Antagonist binding site; Desensitisation; Down regulation; Inositol phosphate formation; Rat; Up regulation

Indexed keywords

2 ANILINO N [2 (3 CHLOROPHENOXY)PROPYL]ACETAMIDINE; CISAPRIDE; G PROTEIN COUPLED RECEPTOR; INOSITOL PHOSPHATE; IODINE 125; MESULERGINE; METHYSERGIDE; N [[3 (4 FLUOROPHENYL) 1 PROPYL] 4 METHYL 4 PIPERIDINYL] 4 AMINO 5 IODO 2 METHOXYBENZAMIDE; PIPAMPERONE; R 93274; RADIOLIGAND; RITANSERIN; SEROTONIN; SEROTONIN 2A RECEPTOR; SEROTONIN 2C RECEPTOR; TRITIUM; UNCLASSIFIED DRUG;

ANIMAL CELL; ARTICLE; CONCENTRATION RESPONSE; CONTROLLED STUDY; DRUG ACTIVITY; DRUG EFFECT; DRUG LABELING; DRUG POTENCY; DRUG RECEPTOR BINDING; HOST CELL; MOUSE; NONHUMAN; PRIORITY JOURNAL; PROTEIN BINDING; PROTEIN EXPRESSION; RAT; RECEPTOR DENSITY; RECEPTOR DOWN REGULATION; SIGNAL TRANSDUCTION;

3T3 CELLS; ANIMALS; BENZAMIDES; BINDING SITES; BINDING, COMPETITIVE; BUTYROPHENONES; DOSE-RESPONSE RELATIONSHIP, DRUG; ERGOLINES; GENE EXPRESSION; INOSITOL PHOSPHATES; IODINE RADIOISOTOPES; MEMBRANES; MICE; PIPERIDINES; RADIOLIGAND ASSAY; RATS; RECEPTOR, SEROTONIN, 5-HT2A; RECEPTOR, SEROTONIN, 5-HT2C; RECEPTORS, SEROTONIN; SEROTONIN; SEROTONIN AGENTS; SEROTONIN ANTAGONISTS; TIME FACTORS; TRITIUM;

EID: 0035800592     PISSN: 00142999     EISSN: None     Source Type: Journal    
DOI: 10.1016/S0014-2999(01)01170-0     Document Type: Article

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