1,4,8-Trimethylfuro[2,3-H]quinolin-2(1H)-one, a new furocoumarin bioisoster

European Journal of Medicinal Chemistry

Volumn 39, Issue 5, 2004, Pages 411-419

  Marzano, Cristina ^a   Chilin, Adriana ^a   Baccichetti, Francarosa ^a   Bettio, Frazia ^a   Guiotto, Adriano ^a   Miolo, Giorgia ^a   Bordin, Franco ^a  

^a UNIVERSITY OF PADOVA   (Italy)

Author keywords

Furoquinolinones; Phototoxicity; Reactive oxygen species; RNA protein cross links

Indexed keywords

1,4,6,8 TETRAMETHYLFURO[2,3 H]QUINOLIN 2(1H) ONE; 1,4,8 TRIMETHYLFURO[2,3 H]QUINOLIN 2(1H) ONE; DEOXYRIBONUCLEOPROTEIN; FUROCOUMARIN; FUROCOUMARIN DERIVATIVE; METHOXSALEN; PHOTOSENSITIZING AGENT; REACTIVE OXYGEN METABOLITE; RNA; UNCLASSIFIED DRUG;

ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL MODEL; ARTICLE; CONCENTRATION RESPONSE; CONTROLLED STUDY; DRUG ACTIVITY; DRUG EFFECT; DRUG MECHANISM; ERYTHEMA; GENOTOXICITY; GUINEA PIG; HUMAN; HUMAN CELL; MAMMAL CELL; NONHUMAN; PHOTOSENSITIZATION; PHOTOTOXICITY; PROTEIN RNA BINDING; PROTEIN SYNTHESIS; REACTION ANALYSIS;

ANIMALS; CELL DIVISION; CELL LINE, TUMOR; CRICETINAE; DNA; DNA REPLICATION; DOSE-RESPONSE RELATIONSHIP, RADIATION; DRUG EVALUATION, PRECLINICAL; FURANS; HELA CELLS; HUMANS; MICE; MOLECULAR STRUCTURE; PHOTOBIOLOGY; PHOTOSENSITIZING AGENTS; PROTEINS; PSORALENS; QUINOLONES; REACTIVE OXYGEN SPECIES; RNA; SKIN; ULTRAVIOLET RAYS;

EID: 1942487856     PISSN: 02235234     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.ejmech.2004.01.008     Document Type: Article

References (28)

1. Parrish J.A., Stern R.S., Pathak M.A., Fitzpatrick T.B. Regan J.D., Parrish J.A. The Science of Photomedicine. 1982;595-624 Plenum Press, New York.
2. Gasparro F.P. 1994;Landes Press, Georgetown, TX.
3. Kirkland D.J., Creed K.L., Mannisto P. Mutat. Res. 116:1983;73-82.
4. Venturini S., Tamaro M., Monti-Bragadin C., Carlassare F. Mutat. Res. 88:1981;17-22.
5. Hook G.J., Heddle J.A., Marshall R.R. Cytogenet. Cell Genet. 35:1983;100-103.
6. Stern R.S. Photodermatol. Photoimmunol. Photomed. 15:1999;37-38.
7. Ben-Hur E., Song P.S. Adv. Rad. Biol. 11:1984;131-171.
8. Bordin F., Carlassare F., Busulini L., Baccichetti F. Photochem. Photobiol. 58:1993;133-136.
9. Bordin F., Dall'Acqua F., Guiotto A. Pharm. Ther. 52:1991;331-363.
10. Rodighiero P., Guiotto A., Chilin A., Bordin F., Baccichetti F., Carlassare F., Vedaldi D., Caffieri S., Pozzan A., Dall'Acqua F. J. Med. Chem. 39:1996;1293-1302.
11. Bordin F., Marzano C., Carlassare F., Rodighiero P., Guiotto A., Caffieri S., Baccichetti F. J. Photochem. Photobiol. B:Biol. 34:1996;159-168.
12. Bordin F., Baccichetti F., Marzano C., Carlassare F., Miolo G., Chilin A., Guiotto A. Photochem. Photobiol. 71:2000;254-262.
13. Fossa P., Mosti L., Menozzi G., Marzano C., Baccichetti F., Bordin F. Bioorg. Med. Chem. 10:2002;743-751.
14. Marzano C., Baccichetti F., Carlassare F., Chilin A., Lora S., Bordin F. Photochem. Photobiol. 71:2000;263-272.
15. Chilin A., Rodighiero P., Pastorini G., Guiotto A. J. Org. Chem. 56:1991;980-983.
16. Kanne D., Straub K., Rapoport H., Hearst J.E. Biochemistry. 21:1982;861-871.
17. Brent T.P. Cancer Research. 44:1984;1887-1892.
18. Musajo L., Rodighiero G. Giese A.C. Photophisiology. VII:1972;115-147 Academic Press, London and New York.
19. Vedaldi D., Dall'Acqua F., Baccichetti F., Carlassare F., Bordin F., Rodighiero P. Il Farmaco. 46:1991;1381-1406.
20. Bianchi L., Bianchi A., Dall'Acqua F., Santamaria L. Mutat. Res. 235:1990;1-7.
21. Dall'Acqua F., Vedaldi D., Baccichetti F., Rodighiero G., Gennaro A. Prous J.R. QSAR in design of bioactive compounds. 1984;87-95. Barcelona.
22. Pathak M.A., Joshi P.C. Biochim. Biophys. Acta. 798:1984;115-126.
23. Baccichetti F., Carlassare F., Marzano C., Guiotto A., Rodighiero P., Chilin A., Bordin F. J. Photochem. Photobiol., B:Biol. 24:1994;101-108.
24. Kraljic I., El Mohsni S. Photochem. Photobiol. 28:1978;577-581.
25. Bridges B.A., Mottershead R.P., Rothwell M.A., Green M.H.L. Chem.-Biol. Interact. 5:1972;77-84.
26. Chilin A., Marzano C., Guiotto A., Manzini P., Baccichetti F., Carlassare F., Bordin F. J. Med. Chem. 42:1999;2936-2945.
27. Kohn K.W. Pharm. Ther. 49:1991;55-77.
28. Allen A.O. "The Radiation Chemistry of Water and Aqueous Solutions". 1961;20-23 Van Nostrand-Reinhold, Princeton, New Jersey.