A fungal nonribosomal peptide synthetase module that can synthesize thiopyrazines

Organic Letters

Volumn 13, Issue 7, 2011, Pages 1758-1761

  Qiao, Kangjian ^a   Zhou, Hui ^a   Xu, Wei ^a   Zhang, Wenjun ^a   Garg, Neil ^a   Tang, Yi ^a  

^a UNIVERSITY OF CALIFORNIA   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

PEPTIDE SYNTHASE; PYRAN DERIVATIVE; THIOL DERIVATIVE; THIOPYRAN;

ARTICLE; ASPERGILLUS; CHEMICAL STRUCTURE; ENZYME SPECIFICITY; ENZYMOLOGY; GENETICS; METABOLISM; MULTIGENE FAMILY; SYNTHESIS;

ASPERGILLUS; MOLECULAR STRUCTURE; MULTIGENE FAMILY; PEPTIDE SYNTHASES; PYRANS; SUBSTRATE SPECIFICITY; SULFHYDRYL COMPOUNDS;

EID: 79953197967     PISSN: 15237060     EISSN: 15237052     Source Type: Journal    
DOI: 10.1021/ol200288w     Document Type: Article

References (27)

1. Hoffmeister, D.; Keller, N. P. Nat. Prod. Rep. 2007, 24, 393
2. Tobert, J. A. Nat. Rev. Drug. Discovery 2003, 2, 517
3. Cox, R. J. Org. Biomol. Chem. 2007, 5, 2010
4. Finking, R.; Marahiel, M. A. Annu. Rev. Microbiol. 2004, 58, 453
5. Bergmann, S.; Schumann, J.; Scherlach, K.; Lange, C.; Brakhage, A. A.; Hertweck, C. Nat. Chem. Biol. 2007, 3, 213
6. Sims, J. W.; Schmidt, E. W. J. Am. Chem. Soc. 2008, 130, 11149
7. Halo, L. M.; Marshall, J. W.; Yakasai, A. A.; Song, Z.; Butts, C. P.; Crump, M. P.; Heneghan, M.; Bailey, A. M.; Simpson, T. J.; Lazarus, C. M.; Cox, R. J. ChemBioChem 2008, 9, 585
8. Seshime, Y.; Juvvadi, P. R.; Tokuoka, M.; Koyama, Y.; Kitamoto, K.; Ebizuka, Y.; Fujii, I. Bioorg. Med. Chem. Lett. 2009, 19, 3288
9. Maiya, S.; Grundmann, A.; Li, X.; Li, S. M.; Turner, G. ChemBioChem 2007, 8, 1736
10. Maiya, S.; Grundmann, A.; Li, S. M.; Turner, G. ChemBioChem 2006, 7, 1062
11. Balibar, C. J.; Walsh, C. T. Biochemistry 2006, 45, 15029
12. Zocher, R.; Nihira, T.; Paul, E.; Madry, N.; Peeters, H.; Kleinkauf, H.; Keller, U. Biochemistry 1986, 25, 550
13. Daniel, J. F.; Filho, E. R. Nat. Prod. Rep. 2007, 24, 1128
14. Yin, W. B.; Grundmann, A.; Cheng, J.; Li, S. M. J. Biol. Chem. 2009, 284, 100
15. Ames, B. D.; Walsh, C. T. Biochemistry 2010, 49, 3351
16. Gao, X.; Chooi, Y.; Ames, B. D.; Wang, P.; Walsh, C. T.; Tang, Y. J. Am. Chem. Soc. 2011, 133 (8) 2729-2741
17. Xu, W.; Cai, X.; Jung, M. E.; Tang, Y. J. Am. Chem. Soc. 2010, 132, 13604
18. Liu, X.; Walsh, C. T. Biochemistry 2009, 48, 8746
19. Gressler, M.; Zaehle, C.; Scherlach, K.; Hertweck, C.; Brock, M. Chem. Biol. 2011, 18, 198.
20. Pfeifer, B. A.; Admiraal, S. J.; Gramajo, H.; Cane, D. E.; Khosla, C. Science 2001, 291, 1790
21. Duerfahrt, T.; Eppelmann, K.; Muller, R.; Marahiel, M. A. Chem. Biol. 2004, 11, 261
22. Kelly, W. L.; Hillson, N. J.; Walsh, C. T. Biochemistry 2005, 44, 13385
23. Samel, S. A.; Schoenafinger, G.; Knappe, T. A.; Marahiel, M. A.; Essen, L. O. Structure 2007, 15, 781
24. Bergendahl, V.; Linne, U.; Marahiel, M. A. Eur. J. Biochem. 2002, 269, 620
25. Marshall, C. G.; Hillson, N. J.; Walsh, C. T. Biochemistry 2002, 41, 244
26. Keating, T. A.; Marshall, C. G.; Walsh, C. T.; Keating, A. E. Nat. Struct. Biol. 2002, 9, 522
27. Dickschat, J. S.; Reichenbach, H.; Wagner-Dobler, I.; Schulz, S. Eur. J. Org. Chem. 2005, 4141