Granulysin delivered by cytotoxic cells damages endoplasmic reticulum and activates caspase-7 in target cells

Journal of Immunology

Volumn 186, Issue 6, 2011, Pages 3497-3504

  Saini, Reena V ^a   Wilson, Christine ^a   Finn, Michael W ^a   Wang, Tianhong ^a   Krensky, Alan M ^a   Clayberger, Carol ^a  

^a NATIONAL CANCER INSTITUTE   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

CASPASE 3; CASPASE 7; CASPASE 9; GRANULYSIN; GRANZYME B; INTERLEUKIN 15; PERFORIN;

ANIMAL CELL; APOPTOSIS; ARTICLE; CELL DEATH; CONTROLLED STUDY; CYTOLYSIS; CYTOTOXIC T LYMPHOCYTE; DISORDERS OF MITOCHONDRIAL FUNCTIONS; ENDOPLASMIC RETICULUM STRESS; ENZYME ACTIVATION; IN VITRO STUDY; MITOCHONDRION; MOUSE; NATURAL KILLER CELL; NONHUMAN; PRIORITY JOURNAL; SPLEEN CELL; WHOLE CELL;

ANIMALS; ANTIGENS, DIFFERENTIATION, T-LYMPHOCYTE; APOPTOSIS; CASPASE 7; CELL LINE, TUMOR; CELLS, CULTURED; CYTOTOXICITY TESTS, IMMUNOLOGIC; ENDOPLASMIC RETICULUM; ENZYME ACTIVATION; HUMANS; K562 CELLS; KILLER CELLS, NATURAL; MICE; MICE, INBRED C57BL; MICE, KNOCKOUT; MICE, TRANSGENIC; SIGNAL TRANSDUCTION; T-LYMPHOCYTES, CYTOTOXIC;

EID: 79953192506     PISSN: 00221767     EISSN: 15506606     Source Type: Journal    
DOI: 10.4049/jimmunol.1003409     Document Type: Article

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