Blocking the gate to ligand entry in human hemoglobin

Journal of Biological Chemistry

Volumn 286, Issue 12, 2011, Pages 10515-10529

  Birukou, Ivan ^a   Soman, Jayashree ^a   Olson, John S ^a  

^a RICE UNIVERSITY   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

BIMOLECULAR RATE CONSTANTS; BIPHASIC; CONFORMATIONAL RELAXATION; DISTAL POCKET; INDOLE RINGS; ISOLATED MUTANTS; LASER PHOTOLYSIS; OPEN CONFORMATION; SIDE CHAINS; TRANSIENT INTERMEDIATE;

HEMOGLOBIN; LIGANDS; PHOTOLYSIS; RATE CONSTANTS;

CONFORMATIONS;

HEMOGLOBIN; HEMOGLOBIN A; TRYPTOPHAN;

AMINO ACID SEQUENCE; ARTICLE; BINDING AFFINITY; BINDING COMPETITION; BINDING KINETICS; BINDING SITE; CONTROLLED STUDY; CRYSTAL STRUCTURE; CRYSTALLIZATION; HUMAN; LIGAND BINDING; PHOTOLYSIS; PRIORITY JOURNAL; PROTEIN ANALYSIS; PROTEIN CONFORMATION; PROTEIN EXPRESSION; PROTEIN PURIFICATION; SEQUENCE ANALYSIS;

AMINO ACID SUBSTITUTION; BINDING SITES; CARBOXYHEMOGLOBIN; HEMOGLOBIN A; HUMANS; KINETICS; LIGANDS; MUTATION, MISSENSE;

EID: 79953185359     PISSN: 00219258     EISSN: 1083351X     Source Type: Journal    
DOI: 10.1074/jbc.M110.176271     Document Type: Article

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