Alkyl isocyanides serve as transition state analogues for ligand entry and exit in myoglobin

Biochemistry

Volumn 49, Issue 24, 2010, Pages 4987-4997

  Blouin, George C ^a   Schweers, Rachel L ^a   Olson, John S ^a  

^a RICE UNIVERSITY   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

ALKYL GROUPS; BINDING POCKETS; DISTAL POCKET; ENTRY AND EXIT; FTIR SPECTROSCOPY; GEMINATE RECOMBINATION; HYDROPHOBIC EFFECT; ISOCYANIDES; LIGAND MOVEMENT; POLAR INTERACTIONS; SIDE CHAINS; SOLVENT PHASE; SPERM WHALES; STERIC INTERACTIONS; STRONG CORRELATION; TERMINAL CARBON ATOMS; TRANSITION-STATE ANALOGUES;

ALKYLATION; ATOMIC SPECTROSCOPY; COMPLEXATION; FOURIER TRANSFORM INFRARED SPECTROSCOPY; HYDROCARBONS; HYDROGEN BONDS; HYDROPHOBICITY; LIGANDS;

CYANIDES;

HISTIDINE; ISONITRILE DERIVATIVE; MYOGLOBIN; OXYGEN;

ARTICLE; HYDROGEN BOND; HYDROPHOBICITY; INFRARED SPECTROSCOPY; LIGAND BINDING; MOLECULAR DYNAMICS; NONHUMAN; PRIORITY JOURNAL; PROTEIN CONFORMATION; SPERM WHALE;

BINDING SITES; CYANIDES; HISTIDINE; KINETICS; LIGANDS; MODELS, MOLECULAR; MOLECULAR CONFORMATION; MUTATION; MYOGLOBIN; NITRIC OXIDE; OXYGEN; PROTEIN BINDING; SPECTROSCOPY, FOURIER TRANSFORM INFRARED;

PHYSETERIDAE;

EID: 77953655671     PISSN: 00062960     EISSN: 15204995     Source Type: Journal    
DOI: 10.1021/bi1001745     Document Type: Article

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