Distal histidine stabilizes bound O2 and acts as a gate for ligand entry in both subunits of adult human hemoglobin

Journal of Biological Chemistry

Volumn 285, Issue 12, 2010, Pages 8840-8854

  Birukou, Ivan ^a   Schweers, Rachel L ^a,b   Olson, John S ^a  

^a RICE UNIVERSITY   (United States)

^b Katten Muchin Rosenman LLP   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

BIPHASIC; DISTAL HISTIDINE; LASER PHOTOLYSIS; LIGAND BINDING; LIGAND CONCENTRATION; LIGAND REBINDING; NO BINDING; RAPID MIXING; SIDE CHAINS;

AMINO ACIDS; HEMOGLOBIN; HYDROGEN BONDS; LIGANDS; ORGANIC ACIDS; PHOSPHATASES; PHOTOLYSIS;

RATE CONSTANTS;

ALANINE; CARBON MONOXIDE; GLUTAMINE; GLYCINE; HEMOGLOBIN; HISTIDINE; IMIDAZOLE; LEUCINE; LIGAND; MUTANT PROTEIN; NITRIC OXIDE; OXYGEN; PHENYLALANINE; PROTEIN SUBUNIT; TRYPTOPHAN; IMIDAZOLE DERIVATIVE;

ALPHA CHAIN; ARTICLE; AUTOOXIDATION; BETA CHAIN; CONTROLLED STUDY; HYDROGEN BOND; LIGAND BINDING; OXYGEN DISSOCIATION CURVE; PHOTOLYSIS; PRIORITY JOURNAL; PROTEIN CONFORMATION; CHEMISTRY; HUMAN; KINETICS; MUTATION; PROTEIN BINDING; THERMODYNAMICS;

CARBON MONOXIDE; HEMOGLOBINS; HISTIDINE; HUMANS; HYDROGEN BONDING; IMIDAZOLES; KINETICS; LIGANDS; MUTATION; NITRIC OXIDE; OXYGEN; PHENYLALANINE; PROTEIN BINDING; PROTEIN CONFORMATION; THERMODYNAMICS;

EID: 77950548846     PISSN: 00219258     EISSN: 1083351X     Source Type: Journal    
DOI: 10.1074/jbc.M109.053934     Document Type: Article

References (64)

1. Perutz, M. F. (1970) Nature 228, 726-739
2. Pauling, L. (1964) Nature 203, 182-183
3. Perutz, M. F., and Mathews, F. S. (1966) J. Mol. Biol. 21, 199-202
4. Jameson, G. B., Molinaro, F. S., Ibers, J. A., Collman, J. P., Brauman, J. I., Rose, E., and Suslick, K. S. (1980) J. Am. Chem. Soc. 102, 3224-3237
5. Slebodnick, C., and Ibers, J. A. (1997) J. Biol. Inorg. Chem. 2, 521-525
6. Traylor, T. G., Deardurff, L. A., Coletta, M., Ascenzi, P., Antonini, E., and Brunori, M. (1983) J. Biol. Chem. 258, 12147-12148
7. Springer, B. A., Egeberg, K. D., Sligar, S. G., Rohlfs, R. J., Mathews, A. J., and Olson, J. S. (1989) J. Biol. Chem. 264, 3057-3060
8. Springer, B. A., Sligar, S. G., Olson, J. S., and Phillips, G. N., Jr. (1994) Chem. Rev. 94, 699-714
9. Momenteau, M., and Reed, C. A. (1994) Chem. Rev. 94, 659-698
10. Olson, J. S., Mathews, A. J., Rohlfs, R. J., Springer, B. A., Egeberg, K. D., Sligar, S. G., Tame, J., Renaud, J. P., and Nagai, K. (1988) Nature 336, 265-266
11. Mathews, A. J., Rohlfs, R. J., Olson, J. S., Tame, J., Renaud, J. P., and Nagai, K. (1989) J. Biol. Chem. 264, 16573-16583
12. Shaanan, B. (1983) J. Mol. Biol. 171, 31-59
13. Olson, J. S., and Phillips, G. N. (1997) J. Biol. Inorg. Chem. 2, 544-552
14. Phillips, G. N., Jr., Teodoro, M., Li, T., Smith, B., Gilson, M. M., and Olson, J. S. (1999) J. Phys. Chem. B 103, 8817-8829
15. Spiro, T. G., and Kozlowski, P. M. (2001) Acc. Chem. Res. 34, 137-144
16. Park, E. S., and Boxer, S. G. (2002) J. Phys. Chem. B 106, 5800-5806
17. Scott, E. E., Gibson, Q. H., and Olson, J. S. (2001) J. Biol. Chem. 276, 5177-5188
18. Olson, J. S., Soman, J., and Phillips, G. N., Jr. (2007) IUBMB Life 59, 552-562
19. Tian, W. D., Sage, J. T., and Champion, P. M. (1993) J. Mol. Biol. 233, 155-166
20. Tian, W. D., Sage, J. T., Champion, P. M., Chien, E., and Sligar, S. G. (1996) Biochemistry 35, 3487-3502
21. Morikis, D., Champion, P. M., Springer, B. A., and Sligar, S. G. (1989) Biochemistry 28, 4791-4800
22. Yang, F., and Phillips, G. N., Jr. (1996) J. Mol. Biol. 256, 762-774
23. Mathews, A. J., and Olson, J. S. (1994) Methods Enzymol. 232, 363-386
24. Unzai, S., Eich, R., Shibayama, N., Olson, J. S., and Morimoto, H. (1998) J. Biol. Chem. 273, 23150-23159
25. Lukin, J. A., Simplaceanu, V., Zou, M., Ho, N. T., and Ho, C. (2000) Proc. Natl. Acad. Sci. U.S.A. 97, 10354-10358
26. Park, S. Y., Yokoyama, T., Shibayama, N., Shiro, Y., and Tame, J. R. (2006) J. Mol. Biol. 360, 690-701
27. Olson, J. S., Rohlfs, R. J., and Gibson, Q. H. (1987) J. Biol. Chem. 262, 12930-12938
28. Looker, D., Mathews, A. J., Neway, J. O., and Stetler, G. L. (1994) Methods Enzymol. 231, 364-374
29. Shen, T. J., Ho, N. T., Simplaceanu, V., Zou, M., Green, B. N., Tam, M. F., and Ho, C. (1993) Proc. Natl. Acad. Sci. U.S.A. 90, 8108-8112
30. Shen, T. J., Ho, N. T., Zou, M., Sun, D. P., Cottam, P. F., Simplaceanu, V., Tam, M. F., Bell, D. A., Jr., and Ho, C. (1997) Protein Eng. 10, 1085-1097
31. Parkhurst, K. M., and Parkhurst, L. J. (1992) Int. J. Biochem. 24, 993-998
32. Salter, M. D., Nienhaus, K., Nienhaus, G. U., Dewilde, S., Moens, L., Pesce, A., Nardini, M., Bolognesi, M., and Olson, J. S. (2008) J. Biol. Chem. 283, 35689-35702
33. Olson, J. S., Foley, E. W., Maillett, D. H., and Paster, E. V. (2003) Methods Mol. Med. 82, 65-91
34. Mathews, A. J., Olson, J. S., Renaud, J. P., Tame, J., and Nagai, K. (1991) J. Biol. Chem. 266, 21631-21639
35. Cassoly, R., and Gibson, Q. (1975) J. Mol. Biol. 91, 301-313
36. Olson, J. S., and Phillips, G. N., Jr. (1996) J. Biol. Chem. 271, 17596
37. Maillett, D. H., Simplaceanu, V., Shen, T. J., Ho, N. T., Olson, J. S., and Ho, C. (2008) Biochemistry 47, 10551-10563
38. Smagghe, B. J., Hoy, J. A., Percifield, R., Kundu, S., Hargrove, M. S., Sarath, G., Hilbert, J. L., Watts, R. A., Dennis, E. S., Peacock, W. J., Dewilde, S., Moens, L., Blouin, G. C., Olson, J. S., and Appleby, C. A. (2009) Biopolymers 91, 1083-1096
39. Trent, J. T., 3rd, Hvitved, A. N., and Hargrove, M. S. (2001) Biochemistry 40, 6155-6163
40. Trent, J. T., 3rd, Watts, R. A., and Hargrove, M. S. (2001) J. Biol. Chem. 276, 30106-30110
41. Hvitved, A. N., Trent, J. T., 3rd, Premer, S. A., and Hargrove, M. S. (2001) J. Biol. Chem. 276, 34714-34721
42. Ikeda-Saito, M., Dou, Y., Yonetani, T., Olson, J. S., Li, T., Regan, R., and Gibson, Q. H. (1993) J. Biol. Chem. 268, 6855-6857
43. Gibson, Q. H., Olson, J. S., McKinnie, R. E., and Rohlfs, R. J. (1986) J. Biol. Chem. 261, 10228-10239
44. Franzen, S. (2002) J. Am. Chem. Soc. 124, 13271-13281
45. Carver, T. E., Rohlfs, R. J., Olson, J. S., Gibson, Q. H., Blackmore, R. S., Springer, B. A., and Sligar, S. G. (1990) J. Biol. Chem. 265, 20007-20020
46. Quillin, M. L., Arduini, R. M., Olson, J. S., and Phillips, G. N., Jr. (1993) J. Mol. Biol. 234, 140-155
47. Jongeward, K. A., Magde, D., Taube, D. J., Marsters, J. C., Traylor, T. G., and Sharma, V. S. (1988) J. Am. Chem. Soc. 110, 380-387
48. Carlson, M. L., Regan, R., Elber, R., Li, H., Phillips, G. N., Jr., Olson, J. S., and Gibson, Q. H. (1994) Biochemistry 33, 10597-10606
49. Nienhaus, K., Olson, J. S., Franzen, S., and Nienhaus, G. U. (2005) J. Am. Chem. Soc. 127, 40-41
50. McKinnie, R. E., and Olson, J. S. (1981) J. Biol. Chem. 256, 8928-8932
51. Olson, J. S., McKinnie, R. E., Mims, M. P., and White, D. K. (1983) J. Am. Chem. Soc. 105, 1522-1527
52. Hargrove, M. S., Barry, J. K., Brucker, E. A., Berry, M. B., Phillips, G. N., Jr., Olson, J. S., Arredondo-Peter, R., Dean, J. M., Klucas, R. V., and Sarath, G. (1997) J. Mol. Biol. 266, 1032-1042
53. Friedman, J. M., Scott, T. W., Fisanick, G. J., Simon, S. R., Findsen, E. W., Ondrias, M. R., and Macdonald, V. W. (1985) Science 229, 187-190
54. Li, T., Quillin, M. L., Phillips, G. N., Jr., and Olson, J. S. (1994) Biochemistry 33, 1433-1446
55. Ray, G. B., Li, X. Y., Ibers, J. A., Sessler, J. L., and Spiro, T. G. (1994) J. Am. Chem. Soc. 116, 162-176
56. Park, E. S., Andrews, S. S., Hu, R. B., and Boxer, S. G. (1999) J. Phys. Chem. B 103, 9813-9817
57. Unno, M., Christian, J. F., Olson, J. S., Sage, J. T., and Champion, P. M. (1998) J. Am. Chem. Soc. 120, 2670-2671
58. Lin, S. H., Yu, N. T., Tame, J., Shih, D., Renaud, J. P., Pagnier, J., and Nagai, K. (1990) Biochemistry 29, 5562-5566
59. Vojtechovský, J., Chu, K., Berendzen, J., Sweet, R. M., and Schlichting, I. (1999) Biophys. J. 77, 2153-2174
60. Rohlfs, R. J., Mathews, A. J., Carver, T. E., Olson, J. S., Springer, B. A., Egeberg, K. D., and Sligar, S. G. (1990) J. Biol. Chem. 265, 3168-3176
61. Thorsteinsson, M. V., Bevan, D. R., Potts, M., Dou, Y., Eich, R. F., Hargrove, M. S., Gibson, Q. H., and Olson, J. S. (1999) Biochemistry 38, 2117-2126
62. Cohen, J., Arkhipov, A., Braun, R., and Schulten, K. (2006) Biophys. J. 91, 1844-1857
63. Elber, R., and Gibson, Q. H. (2008) J. Phys. Chem. B 112, 6147-6154
64. Scherlis, D. A., and Estrin, D. A. (2001) J. Am. Chem. Soc. 123, 8436-8437