Design, synthesis and biological activity of thiazolidine-4-carboxylic acid derivatives as novel influenza neuraminidase inhibitors

Bioorganic and Medicinal Chemistry

Volumn 19, Issue 7, 2011, Pages 2342-2348

  Liu, Yu ^a   Jing, Fanbo ^b   Xu, Yingying ^a   Xie, Yuanchao ^a   Shi, Fangyuan ^a   Fang, Hao ^a   Li, Minyong ^a   Xu, Wenfang ^a  

^a SHANDONG UNIVERSITY   (China)

^b QINGDAO UNIVERSITY   (China)

Author keywords

Biological activity; Influenza; Neuraminidase inhibitor; Thiazolidine

Indexed keywords

2 (2 CARBOXYPHENYL)THIAZOLIDINE 4 CARBOXYLIC ACID; 2 (2 HYDROXY 3 METHOXYPHENYL)THIAZOLIDINE 4 CARBOXYLIC ACID; 2 (2 HYDROXYPHENYL)THIAZOLIDINE 4 CARBOXYLIC ACID; 2 (2 NITROPHENYL)THIAZOLIDINE 4 CARBOXYLIC ACID; 2 (4 CYANOPHENYL)THIAZOLIDINE 4 CARBOXYLIC ACID; 2 PHENYL 4 THIAZOLIDINECARBOXYLIC ACID; 3 (2 AMINOACETYL) 2 (2 CARBOXYPHENYL)THIAZOLIDINE 4 CARBOXYLIC ACID; 3 (2 AMINOACETYL) 2 (2 HYDROXY 3 METHOXYPHENYL)THIAZOLIDINE 4 CARBOXYLIC ACID; 3 (2 AMINOACETYL) 2 (2 HYDROXYPHENYL)THIAZOLIDINE 4 CARBOXYLIC ACID; 3 (2 AMINOACETYL) 2 (2 NITROHPHENYL)THIAZOLIDINE 4 CARBOXYLIC ACID; 3 (2 AMINOACETYL) 2 (4 CYANOPHENYL)THIAZOLIDINE 4 CARBOXYLIC ACID; 3 (2 AMINOACETYL) 2 FURAN 2 YL THIAZOLIDINE 4 CARBOXYLIC ACID; 3 (2 AMINOACETYL) 2 PHENYLTHIAZOLIDINE 4 CARBOXYLIC ACID; 3 (2 CHLOROACETYL) 2 (2 CARBOXYPHENYL)THIAZOLIDINE 4 CARBOXYLIC ACID; 3 (2 CHLOROACETYL) 2 (2 HYDROXYPHENYL)THIAZOLIDINE 4 CARBOXYLIC ACID; 3 (2 CHLOROACETYL) 2 (2 NITROHPHENYL)THIAZOLIDINE 4 CARBOXYLIC ACID; 3 (2 CHLOROACETYL) 2 (4 CYANOPHENYL)THIAZOLIDINE 4 CARBOXYLIC ACID; 3 (2 CHLOROACETYL) 2 PHENYLTHIAZOLIDINE 4 CARBOXYLIC ACID; 3 PHENYLACETYL 2 (2 HYDROXY 3 METHOXYPHENYL)THIAZOLIDINE 4 CARBOXYLIC ACID; 3 PHENYLACETYL 2 FURAN 2 YL THIAZOLIDINE 4 CARBOXYLIC ACID; FURAN 2 YL THIAZOLIDINE 4 CARBOXYLIC ACID; OSELTAMIVIR; SIALIDASE INHIBITOR; TIMONACIC DERIVATIVE; UNCLASSIFIED DRUG; VIRUS SIALIDASE;

ARTICLE; CONTROLLED STUDY; DRUG DESIGN; DRUG POTENCY; DRUG SCREENING; DRUG STRUCTURE; DRUG SYNTHESIS; ENZYME INHIBITION; IC 50; INFLUENZA VIRUS A;

ANTIVIRAL AGENTS; DRUG DESIGN; INFLUENZA A VIRUS, H3N2 SUBTYPE; MODELS, MOLECULAR; NEURAMINIDASE; OSELTAMIVIR; THIAZOLIDINES;

INFLUENZA A VIRUS;

EID: 79953181243     PISSN: 09680896     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.bmc.2011.02.019     Document Type: Article

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